PH30494A - A process for preparing antitumor and anti-bacterial substituted disulfide derivatives from compounds possessing a methyltrithio group - Google Patents

A process for preparing antitumor and anti-bacterial substituted disulfide derivatives from compounds possessing a methyltrithio group

Info

Publication number
PH30494A
PH30494A PH44225A PH44225A PH30494A PH 30494 A PH30494 A PH 30494A PH 44225 A PH44225 A PH 44225A PH 44225 A PH44225 A PH 44225A PH 30494 A PH30494 A PH 30494A
Authority
PH
Philippines
Prior art keywords
methyltrithio
bacterial
group
compounds possessing
preparing antitumor
Prior art date
Application number
PH44225A
Inventor
Mcgahren William James
Sassiver Martin Leon
George A Ellestad
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of PH30494A publication Critical patent/PH30494A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
    • A61K47/6809—Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PH44225A 1989-04-14 1992-04-20 A process for preparing antitumor and anti-bacterial substituted disulfide derivatives from compounds possessing a methyltrithio group PH30494A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33932389A 1989-04-14 1989-04-14
PH4036890 1990-04-11

Publications (1)

Publication Number Publication Date
PH30494A true PH30494A (en) 1997-05-28

Family

ID=23328476

Family Applications (1)

Application Number Title Priority Date Filing Date
PH44225A PH30494A (en) 1989-04-14 1992-04-20 A process for preparing antitumor and anti-bacterial substituted disulfide derivatives from compounds possessing a methyltrithio group

Country Status (5)

Country Link
KR (1) KR0159767B1 (en)
CA (1) CA2014486C (en)
PH (1) PH30494A (en)
SG (1) SG47848A1 (en)
ZA (1) ZA902840B (en)

Also Published As

Publication number Publication date
ZA902840B (en) 1991-12-24
KR0159767B1 (en) 1998-11-16
CA2014486C (en) 2002-10-29
CA2014486A1 (en) 1990-10-14
SG47848A1 (en) 1998-04-17
KR900016243A (en) 1990-11-13

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