PH27229A - Tenidap as an inhibitor of the release of elastase by neutrophils - Google Patents

Tenidap as an inhibitor of the release of elastase by neutrophils

Info

Publication number
PH27229A
PH27229A PH42109A PH42109A PH27229A PH 27229 A PH27229 A PH 27229A PH 42109 A PH42109 A PH 42109A PH 42109 A PH42109 A PH 42109A PH 27229 A PH27229 A PH 27229A
Authority
PH
Philippines
Prior art keywords
tenidap
elastase
neutrophils
release
salts
Prior art date
Application number
PH42109A
Other languages
English (en)
Inventor
Leland David Loose
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PH27229A publication Critical patent/PH27229A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PH42109A 1990-03-19 1991-03-08 Tenidap as an inhibitor of the release of elastase by neutrophils PH27229A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/495,888 US5006547A (en) 1990-03-19 1990-03-19 Tenidap as an inhibitor of the release of elastase by neutrophils

Publications (1)

Publication Number Publication Date
PH27229A true PH27229A (en) 1993-05-04

Family

ID=23970396

Family Applications (1)

Application Number Title Priority Date Filing Date
PH42109A PH27229A (en) 1990-03-19 1991-03-08 Tenidap as an inhibitor of the release of elastase by neutrophils

Country Status (17)

Country Link
US (1) US5006547A (pt)
EP (1) EP0448261B1 (pt)
JP (1) JPH0678230B2 (pt)
KR (1) KR960016511B1 (pt)
AT (1) ATE133071T1 (pt)
AU (1) AU629109B2 (pt)
CA (1) CA2038410C (pt)
DE (1) DE69116404T2 (pt)
DK (1) DK0448261T3 (pt)
HU (1) HU212492B (pt)
IE (1) IE70732B1 (pt)
IL (1) IL97520A (pt)
MY (1) MY107227A (pt)
NZ (1) NZ237450A (pt)
PH (1) PH27229A (pt)
PT (1) PT97062B (pt)
ZA (1) ZA911980B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5008283A (en) * 1990-03-19 1991-04-16 Pfizer Inc. Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase
US5122534A (en) * 1991-02-08 1992-06-16 Pfizer Inc. Use of tenidap to reduce total serum cholesterol, ldl cholesterol and triglycerides
US5545656A (en) * 1995-04-05 1996-08-13 Pfizer Inc. 2-Oxidole-1-carboxamide pharmaceutical agents for the treatment of alzheimer's disease
US6544556B1 (en) 2000-09-11 2003-04-08 Andrx Corporation Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor
EP1390062A4 (en) * 2001-05-02 2005-09-14 Blood Res Center MODULATORS OF ELASTASE INHIBITOR SECRETION
WO2007103540A2 (en) 2006-03-08 2007-09-13 Pharmena North America Inc. Combination therapy with non-selective cox inhibitors to prevent cox-related gastric injuries
EP2886541A1 (en) * 2013-12-19 2015-06-24 Sanofi Oxindole derivatives, preparation thereof and therapeutic use in the treatment of AMPK-related diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4678802A (en) * 1985-07-09 1987-07-07 Pfizer Inc. 1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents
US5036099A (en) * 1987-02-02 1991-07-30 Pfizer Inc. Anhydrous, crystalline sodium salt of 5-chloro-3-(2-thenoyl)-2-oxindole-1-carboxamide
EP0287196B1 (en) * 1987-02-18 1994-11-23 Beecham Group Plc Indole derivatives, process for their preparation and pharmaceutical compositions containing them
US4861794A (en) * 1988-04-13 1989-08-29 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides as inhibitors of interleukin-1 biosynthesis
US4853409A (en) * 1988-04-13 1989-08-01 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides for suppressing T-cell function
DE3814504A1 (de) * 1988-04-29 1989-11-09 Bayer Ag (alpha)-substituierte 4-(chinolin-2-yl-methoxy)phenylessigsaeuren und -ester, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
DE69116404D1 (de) 1996-02-29
HUT60622A (en) 1992-10-28
EP0448261A3 (en) 1992-04-08
NZ237450A (en) 1997-02-24
ZA911980B (en) 1992-10-28
EP0448261A2 (en) 1991-09-25
KR910016327A (ko) 1991-11-05
EP0448261B1 (en) 1996-01-17
DK0448261T3 (da) 1996-02-12
IE70732B1 (en) 1996-12-11
HU212492B (en) 1996-07-29
IL97520A0 (en) 1992-06-21
KR960016511B1 (ko) 1996-12-14
DE69116404T2 (de) 1996-05-30
AU7358691A (en) 1992-08-06
ATE133071T1 (de) 1996-02-15
MY107227A (en) 1995-10-31
JPH0678230B2 (ja) 1994-10-05
JPH04234814A (ja) 1992-08-24
HU910871D0 (en) 1991-09-30
PT97062B (pt) 1998-07-31
IL97520A (en) 1995-12-31
CA2038410C (en) 1995-01-24
IE910861A1 (en) 1991-09-25
PT97062A (pt) 1991-10-31
AU629109B2 (en) 1992-09-24
US5006547A (en) 1991-04-09

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