PH19376A - Antimicrobial aqueous opthalmic solutions - Google Patents

Antimicrobial aqueous opthalmic solutions

Info

Publication number
PH19376A
PH19376A PH27917A PH27917A PH19376A PH 19376 A PH19376 A PH 19376A PH 27917 A PH27917 A PH 27917A PH 27917 A PH27917 A PH 27917A PH 19376 A PH19376 A PH 19376A
Authority
PH
Philippines
Prior art keywords
solutions
ammonium chloride
antimicrobial aqueous
butenyl
hydroxyethyl
Prior art date
Application number
PH27917A
Inventor
Raymond Lloyd Stark
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Publication of PH19376A publication Critical patent/PH19376A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/143—Quaternary ammonium compounds
    • A61L12/145—Polymeric quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Eyeglasses (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

This invention relates to the quaternary ammonium salt, α-4-[1-tris (2-hydroxyethyl) ammonium chloride-2-butenyl] poly [1-dimethyl ammonium chloride-2-butenyl]-w-tris (2-hydroxyethyl) ammonium chloride, providing aqueous disinfecting solutions for contact lenses as well as a preservative for ocular solutions including contact lens treating solutions.
PH27917A 1981-09-28 1982-09-27 Antimicrobial aqueous opthalmic solutions PH19376A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/306,317 US4407791A (en) 1981-09-28 1981-09-28 Ophthalmic solutions

Publications (1)

Publication Number Publication Date
PH19376A true PH19376A (en) 1986-04-02

Family

ID=23184759

Family Applications (1)

Application Number Title Priority Date Filing Date
PH27917A PH19376A (en) 1981-09-28 1982-09-27 Antimicrobial aqueous opthalmic solutions

Country Status (16)

Country Link
US (1) US4407791A (en)
EP (1) EP0076136B1 (en)
JP (1) JPS58501515A (en)
AT (1) ATE46441T1 (en)
AU (1) AU557817B2 (en)
CA (1) CA1194421A (en)
DE (1) DE3279945D1 (en)
DK (1) DK163265C (en)
FI (1) FI78789C (en)
GR (1) GR77661B (en)
IE (1) IE55742B1 (en)
MX (1) MX160782A (en)
NZ (1) NZ201967A (en)
PH (1) PH19376A (en)
WO (1) WO1983001003A1 (en)
ZA (1) ZA826966B (en)

Families Citing this family (128)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1259542A (en) * 1984-09-28 1989-09-19 Francis X. Smith Disinfecting and preserving solutions for contact lenses and methods of use
US5672575A (en) * 1984-12-28 1997-09-30 Alcon Laboratories, Inc. Use of pluronic surfactant to enhance the cleaning effect of pancreatin on contact lenses
US5318717A (en) * 1984-12-28 1994-06-07 Alcon Laboratories, Inc. Use of nonionic surfactant to enhance the cleaning effect of pancreatin on contact lenses
US4609493A (en) * 1984-12-28 1986-09-02 Alcon Laboratories, Inc. Solution and method for removing inorganic and organic deposits from contact lenses
US4599195A (en) * 1984-12-28 1986-07-08 Alcon Laboratories, Inc. Solution and method for removing protein, lipid, and calcium deposits from contact lenses
PH21406A (en) * 1985-04-19 1987-10-15 Ciba Geigy Ag Ophthalmic solution and methods for improving the comfort and safety of contact lenses
US4748189A (en) * 1985-04-19 1988-05-31 Ciba-Geigy Corporation Ophthalmic solutions and methods for improving the comfort and safety of contact lenses
EP0339120A1 (en) * 1988-04-29 1989-11-02 Sterling Drug Inc. Isotropic laundry detergents
US4904698A (en) * 1988-02-11 1990-02-27 Ocusoft Inc. Eyelid cleansing composition
US5165918A (en) * 1988-06-28 1992-11-24 Ciba-Geigy Corporation Antimicrobial ophthalmic solutions containing dodecyl-dimethyl-(2 phenoxyethyl)-ammonium bromide and methods of using the same
US5037647A (en) * 1988-09-15 1991-08-06 Alcon Laboratories, Inc. Aqueous antimicrobial opthalmic solutions comprised of quaternary ammonium compound, citric acid, citrate and sodium chloride
US5300296A (en) * 1989-11-06 1994-04-05 Frank J. Holly Antimicrobial agent for opthalmic formulations
JP3188448B2 (en) * 1989-12-15 2001-07-16 ノバルティス アクチエンゲゼル シャフト pH adjusted protein removal detergent
US5124154A (en) * 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use
US6051611A (en) * 1991-11-08 2000-04-18 Alcon Laboratories, Inc. Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobias
US5547663A (en) * 1991-11-08 1996-08-20 Alcon Laboratories, Inc. Absolute molecular weight polymers and methods for their use
US5512597A (en) * 1991-11-08 1996-04-30 Alcon Laboratories, Inc. Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobials
US5256420A (en) * 1991-12-23 1993-10-26 Ciba-Geigy Corporation Method of imparting antimicrobial acitivity to an ophthalmic composition
US5252246A (en) * 1992-01-10 1993-10-12 Allergan, Inc. Nonirritating nonionic surfactant compositions
US5830508A (en) * 1992-08-06 1998-11-03 Deo Corporation Composition for treating dry eye
US5290572A (en) * 1992-08-06 1994-03-01 Deo Corporation Opthalmic composition for treating dry eye
US5356555A (en) * 1992-09-14 1994-10-18 Allergan, Inc. Non-oxidative method and composition for simultaneously cleaning and disinfecting contact lenses using a protease with a disinfectant
ATE241389T1 (en) * 1992-12-17 2003-06-15 Advanced Medical Optics Inc CONTACT LENS DISINFECTANT SOLUTION CONTAINING OXIDANT AND POLYVINYLPYRROLIDONE
US5340572A (en) * 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
AU6667894A (en) * 1993-04-28 1994-11-21 Alcon Laboratories, Inc. Diamines as antimicrobial agents and use thereof in ophthalmic composition
US5370744B1 (en) * 1993-08-27 1999-11-09 Alcon Lab Inc Process for cleaning and disinfecting contact lenses
US5573726A (en) * 1993-09-22 1996-11-12 Alcon Laboratories, Inc. Use of amidoamines in ophthalmic compositions
US5393491A (en) * 1993-09-22 1995-02-28 Alcon Laboratories, Inc. Use of amidoamines in ophthalmic compositions
US5631005A (en) * 1994-09-21 1997-05-20 Alcon Laboratories, Inc. Use of amidoamines in ophthalmic compositions
US5415837A (en) * 1993-10-25 1995-05-16 Alcon Laboratories, Inc. Use of diamines to disinfect and clean contact lenses
US5532224A (en) * 1993-12-22 1996-07-02 Alcon Laboratories, Inc. Contact lens cleaning composition containing polyalklene oxide modified siloxanes
US5549894A (en) * 1994-01-18 1996-08-27 Allergan, Inc. Disinfecton formulations and methods using D-enantiomeric anti-microbial peptides
AU2553995A (en) * 1994-06-15 1996-01-05 Alcon Laboratories, Inc. Improved method for storing contact lenses
WO1996003158A1 (en) * 1994-07-22 1996-02-08 Alcon Laboratories, Inc. Use of low molecular weight amino acids in ophthalmic compositions
US5536494A (en) * 1994-10-04 1996-07-16 Alcon Laboratories, Inc. Polyethylene oxide-containing quaternary ammunium polymers and pharmaceutical compositions containing an antimicrobial amount of same
US5603929A (en) * 1994-11-16 1997-02-18 Alcon Laboratories, Inc. Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds
US5604190A (en) * 1995-06-07 1997-02-18 Alcon Laboratories, Inc. Stable liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems
US5576278A (en) * 1995-06-07 1996-11-19 Alcon Laboratories, Inc. Stable liquid enzyme compositions and methods of use
US5723421A (en) * 1995-06-07 1998-03-03 Alcon Laboratories, Inc. Stable liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems
US6184189B1 (en) 1995-06-07 2001-02-06 Alcon Laboratories, Inc. Liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems
US5868868A (en) * 1995-06-19 1999-02-09 Alcon Laboratories, Inc. Peg-modified proteases and methods of use in contact lens cleaning
US5605661A (en) * 1995-08-18 1997-02-25 Alcon Laboratories, Inc. Methods of using liquid enzyme compositions containing mixed polyols
US5672213A (en) * 1995-08-18 1997-09-30 Alcon Laboratories, Inc. Liquid enzyme compositions containing aromatic acid derivatives
US5718895A (en) * 1995-11-16 1998-02-17 Alcon Laboratories, Inc. Enzymes with low isoelectric points for use in contact lens cleaning
JP2000505486A (en) * 1996-02-14 2000-05-09 アルコン ラボラトリーズ，インコーポレイテッド Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobial agents
US6358897B1 (en) * 1996-06-07 2002-03-19 Alcon Laboratories, Inc. Alkyl trypsin compositions and methods of use in contact lens cleaning and disinfecting systems
US6034129A (en) * 1996-06-24 2000-03-07 Geltex Pharmaceuticals, Inc. Ionic polymers as anti-infective agents
ES2207748T3 (en) * 1996-08-09 2004-06-01 Alcon Manufacturing Ltd. PRESERVING SYSTEMS FOR PHARMACEUTICAL COMPOSITIONS CONTAINING CYCLODEXTRINES.
CA2266599C (en) * 1996-09-20 2002-03-26 Bausch & Lomb Incorporated Method and composition for rewetting contact lenses and relieving eye dryness
DK0948357T3 (en) * 1996-12-13 2002-07-15 Alcon Lab Inc Use of low molecular weight amino alcohols in ophthalmic compositions
US6228323B1 (en) 1996-12-13 2001-05-08 Alcon Laboratories, Inc. Multi-purpose compositions containing an alkyl-trypsin and methods of use in contact lens cleaning and disinfecting
US6214596B1 (en) 1996-12-18 2001-04-10 Alcon Laboratories, Inc. Liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems
US5788852A (en) * 1997-04-18 1998-08-04 Mescon; Howard Michael Process for preventing accumulation of contaminants in dental suction systems
DK0970175T3 (en) * 1997-07-29 2002-11-04 Alcon Lab Inc Conditioning solutions for the care of hard contact lenses
US6290947B1 (en) 1997-09-19 2001-09-18 Geltex Pharmaceuticals, Inc. Ionic polymers as toxin-binding agents
US6007803A (en) * 1997-09-19 1999-12-28 Geltex Pharmaceuticals, Inc. Ionic polymers as toxin binding agents
US20030129083A1 (en) * 1997-11-26 2003-07-10 Advanced Medical Optics, Inc. Multi purpose contact lens care compositions including propylene glycol or glycerin
ZA9811445B (en) * 1997-12-19 1999-08-16 Alcon Lab Inc Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions.
JP3883739B2 (en) * 1998-05-22 2007-02-21 株式会社メニコン Contact lens bactericidal solution
US20030086986A1 (en) 1998-08-06 2003-05-08 Bruijn Chris De Ophthalmic, pharmaceutical and other healthcare preparations with naturally occurring plant compounds, extracts and derivatives
AU1180300A (en) * 1998-11-16 2000-06-05 Rohto Pharmaceutical Co., Ltd. Liquid ophthalmic preparations
US6482402B1 (en) 1999-05-13 2002-11-19 Geltex Pharmaceuticals, Inc. Antimicrobial compositions and methods
WO2001054687A1 (en) * 2000-01-25 2001-08-02 Alcon Universal Ltd. Ophthalmic anti-allergy compositions suitable for use with contact lenses
US8858961B2 (en) 2000-07-14 2014-10-14 Allergan, Inc. Compositions containing alpha-2-adrenergic agonist components
US20050026924A1 (en) * 2000-07-14 2005-02-03 Allergan, Inc. Compositions containing alpha-2-adrenergic agonist components
US7977376B2 (en) 2001-06-27 2011-07-12 Novartis Ag Olopatadine formulations for topical nasal administration
TWI231759B (en) * 2001-06-27 2005-05-01 Alcon Inc Olopatadine formulations for topical administration
US7402318B2 (en) * 2001-11-14 2008-07-22 Novartis Ag Medical devices having antimicrobial coatings thereon
US20040198828A1 (en) * 2003-01-17 2004-10-07 Abelson Mark B. Combinational use of long-acting and short-acting anti-histamines for ocular allergies
US20050042712A1 (en) * 2003-08-22 2005-02-24 Advanced Medical Optics, Inc. Methods, compositions and instruments to predict antimicrobial or preservative activity
US20050239745A1 (en) * 2004-03-03 2005-10-27 Ophthalmic Research Associates, Inc. Novel topical ophthalmic formulations
US20060270592A1 (en) * 2004-03-19 2006-11-30 Ophthalmic Research Associates, Inc. Use of neurotransmitters and neuropeptides for the treatment of dry eye diseases and related conditions
CA2505836C (en) * 2004-05-06 2013-08-27 Alcon Inc. Topical brimonidine tartrate formulations that lack chlorine dioxide
JP5108234B2 (en) * 2005-02-07 2012-12-26 日本特殊陶業株式会社 Micro heater and sensor
CN103933614B (en) 2005-02-14 2016-03-02 庄臣及庄臣视力保护公司 Comfortable ophthalmic device and manufacture method thereof
US20070254841A1 (en) * 2006-01-25 2007-11-01 Ophthalmic Research Associates, Inc. Formulations and methods for treating dry eye
US20100130580A1 (en) * 2006-01-25 2010-05-27 Aciex Therapeutics, Inc. Formulations and Methods for Treating Dry Eye
DE102006004111B4 (en) * 2006-01-28 2015-11-19 Wöhlk-Contact-Linsen GmbH Contact lens material
US9052529B2 (en) 2006-02-10 2015-06-09 Johnson & Johnson Vision Care, Inc. Comfortable ophthalmic device and methods of its production
JP2009535342A (en) * 2006-04-26 2009-10-01 アーシエックス， インコーポレイテッド Composition for prevention and treatment of eyelid swelling
US20090136598A1 (en) * 2006-04-26 2009-05-28 Aciex, Inc. Compositions for the Treatment and Prevention of Eyelid Swelling
CN101668511A (en) * 2007-02-28 2010-03-10 阿西克斯医疗公司 methods and compositions for normalizing meibomian gland secretions
TW200904485A (en) * 2007-05-18 2009-02-01 Alcon Res Ltd Phospholipid compositions for contact lens care and preservation of pharmaceutical compositions
CA2687717A1 (en) * 2007-05-24 2008-12-18 Aciex Therapeutics, Inc. Formulations and methods for treating dry eye
TWI544927B (en) 2008-03-17 2016-08-11 愛爾康研究有限公司 Pharmaceutical compositions having low concentration of surfactants for promoting bioavailability of therapeutic agents
KR101541303B1 (en) 2008-03-17 2015-08-03 알콘 리서치, 리미티드 Aqueous pharmaceutical compositions containing borate-polyol complexes
TWI454289B (en) * 2008-04-03 2014-10-01 Alcon Res Ltd Use of cis-diol-containing polymer to inhibit the uptake of cationic biocides into hydrogel biomaterials
KR20110025760A (en) * 2008-05-19 2011-03-11 알콘 리서치, 리미티드 Pharmaceutical compositions having carboxyvinyl polymer and povidone polymer
CA2725523C (en) * 2008-05-28 2017-01-10 Alcon Research, Ltd. Self-preserved emulsions
US8093352B2 (en) * 2008-08-05 2012-01-10 Alcon Research, Ltd. Polyalkylene oxide polyquaternary ammonium biocides
TW201010727A (en) * 2008-09-03 2010-03-16 Alcon Res Ltd Pharmaceutical composition having relatively low ionic strength
TW201023912A (en) * 2008-12-05 2010-07-01 Alcon Res Ltd Pharmaceutical suspension
RU2011130552A (en) * 2008-12-22 2013-01-27 Алькон Рисерч, Лтд. COMPOSITIONS OF LOCAL EYE-SOLUTIONS FOR DELIVERY OF EFFECTIVE CONCENTRATIONS OF AN ACTIVE AGENT TO THE REAR SEGMENT OF THE EYE
US8431751B1 (en) 2008-12-24 2013-04-30 Alcon Research, Ltd. Polymeric quaternary ammonium compounds with vicinal hydroxy groups
US20100197702A1 (en) * 2009-02-04 2010-08-05 Hellberg Mark R Ophthalmic composition with nitric oxide donor compound and method of forming and using same
US8912236B2 (en) * 2009-03-03 2014-12-16 Alcon Research, Ltd. Pharmaceutical composition for delivery of receptor tyrosine kinase inhibiting (RTKi) compounds to the eye
CA2753837A1 (en) * 2009-03-03 2010-09-10 Alcon Research, Ltd. Pharmaceutical composition for delivery of receptor tyrosine kinase inhibiting (rtki) compounds to the eye
US9254286B2 (en) 2009-03-17 2016-02-09 Aciex Therapeutics, Inc. Ophthalmic formulations of cetirizine and methods of use
US8569273B2 (en) 2009-03-17 2013-10-29 Aciex Therapeutics, Inc. Ophthalmic formulations of cetirizine and methods of use
CA2754996A1 (en) * 2009-03-17 2010-09-23 Aciex Therapeutics, Inc. Ophthalmic formulations of ketotifen and methods of use
TW201038295A (en) * 2009-04-17 2010-11-01 Alcon Res Ltd Aqueous ophthalmic compositions containing anionic therapeutic agents
US8349303B1 (en) 2009-04-29 2013-01-08 Bausch & Lomb Incorporated Polymeric quaternium compounds
WO2010141834A1 (en) * 2009-06-05 2010-12-09 Aciex Therapeutics, Inc. Ophthalmic formulations of fluticasone and methods of use
TWI489997B (en) * 2009-06-19 2015-07-01 Alcon Res Ltd Aqueous pharmaceutical compositions containing borate-polyol complexes
TWI478730B (en) 2009-12-03 2015-04-01 Alcon Res Ltd Ophthalmic emulsion
MX2012008110A (en) * 2010-01-11 2012-10-03 Gtx Inc Methods of treating meibomian gland dysfunction.
EP2359690A1 (en) 2010-02-23 2011-08-24 East Coast Pharmaceutical Research LLC Multiplication of the effectiveness of anti-infective agents by a composition including both a dispersant agent and a metal reversal agent
JP2014501748A (en) 2010-12-21 2014-01-23 リコファーマ アーベー Substitute for tears
US20120225918A1 (en) 2011-03-03 2012-09-06 Voom, Llc Compositions and Methods for Non-Surgical Treatment of Ptosis
CA2833596A1 (en) 2011-04-22 2012-10-26 Alcon Research, Ltd. Ophthalmic composition with a viscosity enhancement system having two different viscosity enhancing agents
RU2013152013A (en) 2011-04-22 2015-05-27 Алькон Рисерч, Лтд. OPHTHALMIC COMPOSITION WITH A VISCOSITY INCREASING SYSTEM HAVING TWO DIFFERENT AGENCY INCREASING VISCOSITY
TWI544922B (en) 2011-05-19 2016-08-11 愛爾康研究有限公司 High concentration olopatadine ophthalmic composition
TW201336527A (en) 2012-02-10 2013-09-16 Alcon Res Ltd Aqueous pharmaceutical composition with enhanced stability
US8765725B2 (en) 2012-05-08 2014-07-01 Aciex Therapeutics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
MX361886B (en) 2012-05-08 2018-12-18 Nicox Ophthalmics Inc Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof.
US9815865B2 (en) 2013-01-07 2017-11-14 Nicox Ophthalmics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
WO2014135984A2 (en) 2013-03-07 2014-09-12 Recopharma Ab Glycosylated mucin-immunoglobulin fusion protein coated device
US10174006B2 (en) 2013-06-06 2019-01-08 Novartis Ag Topical aqueous ophthalmic compositions containing a 1H-indole-1-carboxamide derivative and use thereof for treatment of ophthalmic disease
HUE038809T2 (en) 2013-12-17 2018-11-28 Novartis Ag A silicone hydrogel lens with a crosslinked hydrophilic coating
EP3842047B1 (en) 2015-09-24 2024-08-07 Matrix Biology Institute High elasticity hyaluronan compositions and methods of use thereof
EP3436467A4 (en) 2016-03-30 2020-03-18 Ayuvis Research, Inc. Novel compositions and therapeutic methods
TW201938141A (en) 2018-02-21 2019-10-01 瑞士商諾華公司 Lipid- based ophthalmic emulsion
WO2020010090A1 (en) 2018-07-02 2020-01-09 Ayuvis Research, Inc. Novel immunodulating small molecules
JP6994061B2 (en) 2019-02-15 2022-01-14 ノバルティス アーゲー Preparation of 4- (7-hydroxy-2-isopropyl-4-oxo-4H-quinazoline-3-yl) -benzonitrile
EP4431497A1 (en) 2019-02-15 2024-09-18 Bausch + Lomb Ireland Limited Crystalline forms of 4-(7-hydroxy-2-isopropyl-4-oxo-4h-quinazolin-3-yl)-benzonitrile and formulations thereof
JP2023536938A (en) 2020-08-06 2023-08-30 ノバルティス アーゲー Crystal forms of 4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile and formulations thereof
US20240156786A1 (en) 2021-03-03 2024-05-16 Voom, Llc Compositions and methods for treatment of blepharitis
WO2024062389A1 (en) 2022-09-21 2024-03-28 Bausch + Lomb Ireland Limited Crystalline polymorph forms of a trpv1 antagonist and formulations thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USB724600I5 (en) * 1968-04-26
US3639576A (en) * 1968-06-19 1972-02-01 Barnes Hind Pharm Inc Resterilizing contact lens solution
US4005193A (en) * 1974-08-07 1977-01-25 Millmaster Onyx Corporation Microbiocidal polymeric quaternary ammonium compounds
US4026945A (en) * 1974-10-03 1977-05-31 Millmaster Onyx Corporation Anti-microbial quaternary ammonium co-polymers
US3966904A (en) * 1974-10-03 1976-06-29 Millmaster Onyx Corporation Quaternary ammonium co-polymers for controlling the proliferation of bacteria
US3961042A (en) * 1974-10-03 1976-06-01 Millmaster Onyx Corporation Quaternary ammonium co-polymers for controlling the proliferation of bacteria
US4012446A (en) * 1974-10-29 1977-03-15 Millmaster Onyx Corporation Capped polymers
US4027020A (en) * 1974-10-29 1977-05-31 Millmaster Onyx Corporation Randomly terminated capped polymers
US4025945A (en) * 1975-07-25 1977-05-24 Rca Corporation Color function display system
GB2027040B (en) * 1978-04-26 1982-09-29 Smith & Nephew Pharma Polymers of diallylamine quarternary salts sterilizing agents
CA1138341A (en) * 1980-01-23 1982-12-28 Leszek J. Wolfram Waving composition from a reducing agent and cationic polymer

Also Published As

Publication number Publication date
DK163265B (en) 1992-02-10
IE55742B1 (en) 1991-01-02
EP0076136A2 (en) 1983-04-06
JPH0254804B2 (en) 1990-11-22
GR77661B (en) 1984-09-25
CA1194421A (en) 1985-10-01
DK223883D0 (en) 1983-05-19
NZ201967A (en) 1985-03-20
FI78789C (en) 1989-09-11
AU9050382A (en) 1983-04-08
FI831770A0 (en) 1983-05-19
EP0076136B1 (en) 1989-09-20
WO1983001003A1 (en) 1983-03-31
EP0076136A3 (en) 1985-04-17
AU557817B2 (en) 1987-01-08
IE822338L (en) 1983-03-28
US4407791A (en) 1983-10-04
DK163265C (en) 1992-07-06
DK223883A (en) 1983-05-19
JPS58501515A (en) 1983-09-08
ZA826966B (en) 1983-07-27
MX160782A (en) 1990-05-16
FI78789B (en) 1989-05-31
ATE46441T1 (en) 1989-10-15
DE3279945D1 (en) 1989-10-26
FI831770L (en) 1983-05-19

Similar Documents

Publication Publication Date Title
PH19376A (en) Antimicrobial aqueous opthalmic solutions
DE3270469D1 (en) Contact lens rejuvenating solution
AU557730B2 (en) Lens sterilizing solution using chlorhexidine
CA2165161A1 (en) Contact Lens Solution Containing Cationic Glycoside
CA2098299A1 (en) Method and Composition for Disinfecting Contact Lenses
ATE375174T1 (en) COMPOSITION AND METHOD FOR CARE OF CONTACT LENSES
MY118228A (en) Treatment of contact lenses with aqueous solution comprising a biguanide disinfectant stabilized by tyloxapol
RU93048171A (en) METHOD AND COMPOSITION FOR CONTACT LENS DISINFECTION
EP0076857A4 (en) Spectacle frame for multi-focus spectacles.
AR031417A1 (en) WATER DISINFECTANT SYSTEMS
DE3269093D1 (en) Cleaning solution
AU591484B2 (en) Ophthalmic solutions and methods for improving the comfort and safety of contact lenses
EP0349487A3 (en) Antimicrobial ophthalmic solutions containing dodecyl-dimethyl-(2-phenoxyethyl)-ammonium bromide and methods of using the same
IE872087L (en) Treating contact lenses
FR2395034A1 (en)
JPS574920A (en) Prescription of 5-fluoro-2-methyl-1- (p-methylthiobenzylidene)-3-indenylacetic acid