PH14378A - Anti-inflammatory 4,5-diaryl-2-(substituted-thio)pyrroles and their correpondence sulfoxides and sulfones - Google Patents

Anti-inflammatory 4,5-diaryl-2-(substituted-thio)pyrroles and their correpondence sulfoxides and sulfones

Info

Publication number
PH14378A
PH14378A PH22271A PH22271A PH14378A PH 14378 A PH14378 A PH 14378A PH 22271 A PH22271 A PH 22271A PH 22271 A PH22271 A PH 22271A PH 14378 A PH14378 A PH 14378A
Authority
PH
Philippines
Prior art keywords
correpondence
pyrroles
sulfoxides
sulfones
diaryl
Prior art date
Application number
PH22271A
Other languages
English (en)
Inventor
S Cherkopsky
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of PH14378A publication Critical patent/PH14378A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/323Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72Hydrazones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333Radicals substituted by oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
PH22271A 1978-03-13 1979-03-09 Anti-inflammatory 4,5-diaryl-2-(substituted-thio)pyrroles and their correpondence sulfoxides and sulfones PH14378A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88633778A 1978-03-13 1978-03-13
US97220178A 1978-12-28 1978-12-28
US1025979A 1979-02-08 1979-02-08

Publications (1)

Publication Number Publication Date
PH14378A true PH14378A (en) 1981-06-17

Family

ID=27359191

Family Applications (1)

Application Number Title Priority Date Filing Date
PH22271A PH14378A (en) 1978-03-13 1979-03-09 Anti-inflammatory 4,5-diaryl-2-(substituted-thio)pyrroles and their correpondence sulfoxides and sulfones

Country Status (17)

Country Link
EP (1) EP0005156B1 (de)
JP (1) JPS54141766A (de)
AR (2) AR225739A1 (de)
AU (1) AU527243B2 (de)
CA (1) CA1126275A (de)
DE (1) DE2963707D1 (de)
DK (1) DK75779A (de)
ES (2) ES478556A1 (de)
FI (1) FI790852A (de)
GR (1) GR66513B (de)
IL (1) IL56856A (de)
MX (1) MX5685E (de)
NO (1) NO790821L (de)
NZ (1) NZ189881A (de)
PH (1) PH14378A (de)
PT (1) PT69336A (de)
YU (1) YU58979A (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4267184A (en) * 1979-02-08 1981-05-12 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-2-(substituted-thio)pyrroles and their corresponding sulfoxides and sulfones
DK350280A (da) * 1979-08-27 1981-02-28 Du Pont Fremgangsmaade til fremstilling af 4,5-diaryl-alfapolyfluoralkyl-1h-pyrrol-2-methanoler og 1-(4,5-diaryl-1h-pyrrol-2-yl)-polyfluoralkanoner
US4267190A (en) * 1980-04-18 1981-05-12 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-α,α-bis(polyfluoromethyl)-1H-pyrrole-2-methanethiols
EP0044485A1 (de) * 1980-07-21 1982-01-27 E.I. Du Pont De Nemours And Company Entzündungshemmende 2,3-Diaryl-5-(2,2,2-trifluor-1-(trifluormethyl)ethyl)-1H-pyrrole
DE3317653A1 (de) * 1983-05-14 1984-11-15 Gödecke AG, 1000 Berlin 2-alkylthio-1-aminoalkyl-2-pyrrolin-3-carbonitrile, verfahren zu deren herstellung sowie deren verwendung bei der prophylaxe und therapie thrombotischer zustaende
US5306827A (en) * 1991-12-04 1994-04-26 American Cyanamid Company Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents
US5492925A (en) * 1993-08-31 1996-02-20 American Cyanamid Company Thienyl-and furylpyrrole insecticidal and acaricidal agents
FR2874012B1 (fr) * 2004-08-09 2008-08-22 Sanofi Synthelabo Derives de pyrrole, leur preparation et leur utlisation en therapeutique
ES2770027T3 (es) 2009-02-25 2020-06-30 Takeda Pharmaceuticals Co Procedimiento para producir compuesto de pirrol

Also Published As

Publication number Publication date
AR224276A1 (es) 1981-11-13
DK75779A (da) 1979-09-14
GR66513B (de) 1981-03-24
NZ189881A (en) 1981-02-11
JPS54141766A (en) 1979-11-05
EP0005156A1 (de) 1979-11-14
NO790821L (no) 1979-09-14
EP0005156B1 (de) 1982-09-22
IL56856A0 (en) 1979-05-31
DE2963707D1 (en) 1982-11-04
IL56856A (en) 1982-09-30
YU58979A (en) 1983-04-30
MX5685E (es) 1983-12-09
PT69336A (en) 1979-04-01
FI790852A (fi) 1979-09-14
ES484196A1 (es) 1980-05-16
AR225739A1 (es) 1982-04-30
AU4504079A (en) 1979-09-20
AU527243B2 (en) 1983-02-24
ES478556A1 (es) 1979-12-16
CA1126275A (en) 1982-06-22

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