PH12019502629A1 - Liquid composition including alginic acid or pharmaceutically acceptable salt thereof and colloidal polysaccharide - Google Patents

Liquid composition including alginic acid or pharmaceutically acceptable salt thereof and colloidal polysaccharide

Info

Publication number
PH12019502629A1
PH12019502629A1 PH12019502629A PH12019502629A PH12019502629A1 PH 12019502629 A1 PH12019502629 A1 PH 12019502629A1 PH 12019502629 A PH12019502629 A PH 12019502629A PH 12019502629 A PH12019502629 A PH 12019502629A PH 12019502629 A1 PH12019502629 A1 PH 12019502629A1
Authority
PH
Philippines
Prior art keywords
endoscopic
liquid
pharmaceutically acceptable
acceptable salt
alginic acid
Prior art date
Application number
PH12019502629A
Inventor
Eun Jung Lee
Cheol Woo Lee
Original Assignee
Korea Mcnultys Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Mcnultys Co Ltd filed Critical Korea Mcnultys Co Ltd
Publication of PH12019502629A1 publication Critical patent/PH12019502629A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/042Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/145Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/06Flowable or injectable implant compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/34Materials or treatment for tissue regeneration for soft tissue reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The present invention relates to a liquid-phase composition containing alginic acid or a pharmaceutically acceptable salt thereof and a colloidal polysaccharide, the composition being suitable as a medical biomaterial for tissue restoration used to elevate mucosal tissue of stomach, bowels, or the like when the mucosal tissue is subjected to endoscopic excision, and more specifically, to a liquid-phase composition, which is a medical pharmaceutical composition to be injected into the submucosal layer in endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD), wherein the liquid-phase composition contains alginic acid having a weight average molecular weight of 100,000 to less than 200,000 or a pharmaceutically acceptable salt thereof, and a colloidal polysaccharide. According to the present invention, the liquid-phase composition can be effectively used as a local submucosal injection agent which superbly sustains injection-induced elevation of mucous membranes during endoscopic mucosal resection or endoscopic submucosal dissection.
PH12019502629A 2017-06-12 2019-11-22 Liquid composition including alginic acid or pharmaceutically acceptable salt thereof and colloidal polysaccharide PH12019502629A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020170073128A KR101884467B1 (en) 2017-06-12 2017-06-12 Liquid composition comprising alginate or a pharmaceutically acceptable salt thereof, and polysaccharide colloids
PCT/KR2018/006617 WO2018230915A1 (en) 2017-06-12 2018-06-11 Liquid-phase composition containing alginic acid or pharmaceutically acceptable salt thereof and colloidal polysaccharide

Publications (1)

Publication Number Publication Date
PH12019502629A1 true PH12019502629A1 (en) 2020-06-08

Family

ID=63251399

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12019502629A PH12019502629A1 (en) 2017-06-12 2019-11-22 Liquid composition including alginic acid or pharmaceutically acceptable salt thereof and colloidal polysaccharide

Country Status (7)

Country Link
US (1) US11071807B2 (en)
EP (1) EP3639862A4 (en)
JP (1) JP6901657B2 (en)
KR (1) KR101884467B1 (en)
CN (1) CN110740761B (en)
PH (1) PH12019502629A1 (en)
WO (1) WO2018230915A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11679076B2 (en) * 2020-08-06 2023-06-20 T-ACE Medical Co., Ltd. Composition for submucosal injection and preparation method thereof
CN114377214A (en) * 2022-03-01 2022-04-22 南京工业大学 Injectable sodium alginate hydrogel for assisting EMR or ESD operation
WO2023201575A1 (en) * 2022-04-20 2023-10-26 江苏扬子江医疗科技股份有限公司 Injection type hydrogel, preparation method therefor, and use of injection type hydrogel as submucosal injection for endoscope adjuvant treatment

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2005039672A1 (en) * 2003-10-23 2007-02-22 株式会社信州Tlo Method of thickening thickening composition and needle device
US20050208134A1 (en) * 2004-02-25 2005-09-22 Shlomo Magdassi Biocompatible polymeric beads and use thereof
MX2009001608A (en) * 2006-08-24 2009-02-23 Unilever Nv Liquid satiety enhancing composition.
JP5613567B2 (en) * 2007-11-29 2014-10-22 ジェンザイム・コーポレーション Endoscopic mucosal resection using purified reverse thermosensitive polymer
WO2013077357A1 (en) 2011-11-25 2013-05-30 日本製薬株式会社 Submucosal cushioning agent
KR101436406B1 (en) 2011-12-29 2014-09-02 주식회사 안랩 Client, server, system and method for updating data based on peer to peer
CN103071181B (en) * 2013-02-01 2015-04-29 刘昌桂 Hydrogel as well as preparation method and purpose of hydrogel
JP6099044B2 (en) * 2013-03-26 2017-03-22 国立大学法人 大分大学 Medical composition
EP3013270A4 (en) * 2013-06-26 2017-02-22 Vicut Medical Devices Ltd. Device, kit and method for prolonged lifting of a tissue during endoscopic procedure
KR102077158B1 (en) 2013-07-10 2020-02-13 삼성전자 주식회사 Apparatus and method for operating message function which is associated memo function
KR101531091B1 (en) 2013-07-19 2015-06-24 유재원 Injectable agent for tissue repair treatment comprising the substance polymerizing hydrophobic biocompatible polymer and hydrophilic biocompatible polymer
US20150099928A1 (en) * 2013-10-07 2015-04-09 Boston Scientific Scimed, Inc. Injectable compositions
ITMI20131927A1 (en) * 2013-11-20 2015-05-21 Cosmo Technologies Ltd EMULSIONS OR MICROEMULSIONS FOR USE IN ENDOSCOPIC MUCOSAL RESECTIONING AND / OR ENDOSCOPIC SUBMUCOSAL DISSECTION. EMULSIONS OR MICROEMULSIONS FOR USE IN ENDOSCOPIC MUCOSAL RESECTION AND / OR ENDOSCOPIC SUBMUCOSAL DISSECTION
ITMI20131924A1 (en) * 2013-11-20 2015-05-21 Cosmo Technologies Ltd EMULSIONS OR MICROEMULSIONS FOR USE IN ENDOSCOPIC AND MUCOSAL RESECTIONING AND / OR
KR20160033897A (en) * 2014-09-19 2016-03-29 주식회사 덱스레보 Composition for tissue repair treatment and methods of manufacturing the same
KR20160043547A (en) 2014-10-13 2016-04-22 (주)에코팜 Natural disinfection for horticultural crops produced thereby and method of manufacturing pesticides and natural disinfection and pesticides
US10179190B2 (en) * 2015-05-29 2019-01-15 Boston Scientific Scimed, Inc. Compositions and methods for treatment of tissue
CN105251048A (en) * 2015-10-16 2016-01-20 山东福瑞达医药集团公司 Injectable cartilage tissue protection and repair material containing xanthan gum

Also Published As

Publication number Publication date
JP2020523059A (en) 2020-08-06
JP6901657B2 (en) 2021-07-14
KR101884467B1 (en) 2018-08-02
EP3639862A1 (en) 2020-04-22
US11071807B2 (en) 2021-07-27
CN110740761B (en) 2022-10-25
US20200114047A1 (en) 2020-04-16
CN110740761A (en) 2020-01-31
EP3639862A4 (en) 2021-04-07
WO2018230915A1 (en) 2018-12-20

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