PH12019500671A1 - Granular preparation - Google Patents

Granular preparation

Info

Publication number
PH12019500671A1
PH12019500671A1 PH12019500671A PH12019500671A PH12019500671A1 PH 12019500671 A1 PH12019500671 A1 PH 12019500671A1 PH 12019500671 A PH12019500671 A PH 12019500671A PH 12019500671 A PH12019500671 A PH 12019500671A PH 12019500671 A1 PH12019500671 A1 PH 12019500671A1
Authority
PH
Philippines
Prior art keywords
granular preparation
valine
leucine
present
isoleucine
Prior art date
Application number
PH12019500671A
Inventor
Yasushi Tanikawa
Chisato Makino
Nobutaka Ninomiya
Jun Kosaka
Original Assignee
Ea Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ea Pharma Co Ltd filed Critical Ea Pharma Co Ltd
Publication of PH12019500671A1 publication Critical patent/PH12019500671A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Abstract

The present invention provides a granular preparation which has an improved feel of ingestion and comprises isoleucine, leucine and valine. The present invention relates to a granular preparation comprising isoleucine, leucine and valine as active component, the granular preparation containing a gelling agent.
PH12019500671A 2017-02-21 2019-03-28 Granular preparation PH12019500671A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017030368 2017-02-21
PCT/JP2018/005990 WO2018155435A1 (en) 2017-02-21 2018-02-20 Granular preparation

Publications (1)

Publication Number Publication Date
PH12019500671A1 true PH12019500671A1 (en) 2019-07-24

Family

ID=63253165

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12019500671A PH12019500671A1 (en) 2017-02-21 2019-03-28 Granular preparation

Country Status (6)

Country Link
JP (1) JP7080215B2 (en)
KR (1) KR102555664B1 (en)
CN (1) CN109789120A (en)
PH (1) PH12019500671A1 (en)
SG (1) SG10202109130WA (en)
WO (1) WO2018155435A1 (en)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL342710A1 (en) * 1997-12-20 2001-07-02 Genencor Int Matrix granule
BR9912533A (en) * 1998-07-31 2002-02-13 Otsuka Pharma Co Ltd Pharmaceutical composition having improved taste
JP3211824B1 (en) * 2000-10-26 2001-09-25 味の素株式会社 Pharmaceutical granule preparation containing branched-chain amino acid and method for producing the same
KR101168189B1 (en) * 2003-10-29 2012-07-25 시오노기세이야쿠가부시키가이샤 Process for producing coated preparation having relieved unpleasantness
TWI503128B (en) * 2007-07-31 2015-10-11 Ajinomoto Kk A granule preparation containing an amino acid with excellent taste
PE20141034A1 (en) * 2008-03-11 2014-09-10 Takeda Pharmaceutical SOLID ORAL DISINTEGRATION PREPARATION
JP5360368B2 (en) * 2008-09-05 2013-12-04 味の素株式会社 Amino acid preparation for oral use with improved dosage
JP5515943B2 (en) * 2009-10-02 2014-06-11 味の素株式会社 Granules containing branched chain amino acids and method for producing the same
JP2013014590A (en) * 2012-08-02 2013-01-24 Otsuka Pharmaceut Co Ltd Atrophy inhibitor of alimentary canal and kidney

Also Published As

Publication number Publication date
JP7080215B2 (en) 2022-06-03
WO2018155435A1 (en) 2018-08-30
SG10202109130WA (en) 2021-09-29
JPWO2018155435A1 (en) 2019-12-12
KR102555664B1 (en) 2023-07-18
KR20190117469A (en) 2019-10-16
CN109789120A (en) 2019-05-21

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