PH12019500020A1 - In vitro release testing method and evaluation method of polymer micelle preparation containing poorly water-soluble drug - Google Patents

In vitro release testing method and evaluation method of polymer micelle preparation containing poorly water-soluble drug

Info

Publication number
PH12019500020A1
PH12019500020A1 PH12019500020A PH12019500020A PH12019500020A1 PH 12019500020 A1 PH12019500020 A1 PH 12019500020A1 PH 12019500020 A PH12019500020 A PH 12019500020A PH 12019500020 A PH12019500020 A PH 12019500020A PH 12019500020 A1 PH12019500020 A1 PH 12019500020A1
Authority
PH
Philippines
Prior art keywords
poorly water
soluble drug
polymer micelle
preparation containing
vitro release
Prior art date
Application number
PH12019500020A
Inventor
Gyeong Hae Kim
Sa Won Lee
Hye Jin Jang
Original Assignee
Samyang Biopharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Samyang Biopharmaceuticals filed Critical Samyang Biopharmaceuticals
Publication of PH12019500020A1 publication Critical patent/PH12019500020A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention relates to: a method for testing the in vitro release of a polymer micelle preparation containing a poorly water-soluble drug; a method for evaluating a polymer micelle preparation containing a poorly water-soluble drug; and a polymer micelle composition containing a poorly water-soluble drug.
PH12019500020A 2016-07-06 2019-01-03 In vitro release testing method and evaluation method of polymer micelle preparation containing poorly water-soluble drug PH12019500020A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20160085450 2016-07-06
PCT/KR2017/007198 WO2018008986A1 (en) 2016-07-06 2017-07-05 In vitro release testing method and evaluation method of polymer micelle preparation containing poorly water-soluble drug

Publications (1)

Publication Number Publication Date
PH12019500020A1 true PH12019500020A1 (en) 2019-10-28

Family

ID=60901364

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12019500020A PH12019500020A1 (en) 2016-07-06 2019-01-03 In vitro release testing method and evaluation method of polymer micelle preparation containing poorly water-soluble drug

Country Status (5)

Country Link
JP (1) JP6810239B2 (en)
KR (1) KR101906321B1 (en)
CN (1) CN109475498B (en)
PH (1) PH12019500020A1 (en)
WO (1) WO2018008986A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114712312B (en) * 2020-12-18 2023-10-24 浙江圣兆药物科技股份有限公司 Method for controlling release of microsphere active ingredients
CN114088901B (en) * 2021-11-19 2023-12-22 江苏科技大学 General degradable drug-carrying film in-vitro release data optimization analysis method
CN115308320B (en) * 2022-06-29 2024-03-26 昆明理工大学 Method for quantifying hydrophobic organic pollutants in soil and forming residual combined state through action of hydrophobic organic pollutants and humic acid

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0914102T3 (en) * 1996-05-24 2006-01-09 Angiotech Pharm Inc Preparations and methods for treating or preventing diseases of the body canals
JPH11344485A (en) * 1998-03-30 1999-12-14 Eisai Co Ltd Elution test method for fat-soluble drug
AU2001258872C1 (en) * 2000-05-12 2005-05-26 Samyang Biopharmaceuticals Corporation Method for the preparation of polymeric micelle via phase separation of block copolymer
CN100471886C (en) * 2003-10-10 2009-03-25 株式会社三养社 Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery
CA2523987C (en) * 2003-10-10 2009-08-04 Samyang Corporation Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery
KR101312417B1 (en) * 2005-05-11 2013-09-27 니폰 가야꾸 가부시끼가이샤 Polymeric derivative of cytidine metabolic antagonist
KR100664558B1 (en) * 2005-05-23 2007-01-03 박기동 Amphiphilic copolymer having multi functional group and preparation method thereof
WO2008143127A1 (en) 2007-05-17 2008-11-27 Ajinomoto Co., Inc. Method of measuring the activity of lipid-modified enzyme
KR101024742B1 (en) * 2007-12-31 2011-03-24 주식회사 삼양사 Amphiphilic Block Copolymer Micelle Composition Containing Taxane and Manufacturing Process of The Same
JPWO2010058840A1 (en) * 2008-11-20 2012-04-19 テルモ株式会社 Drug release means from liposome and evaluation method for release
EP2480207B1 (en) * 2009-09-25 2016-11-09 Wisconsin Alumni Research Foundation Micelle encapsulation of therapeutic agents
ES2737800T3 (en) * 2013-03-01 2020-01-16 California Inst Of Techn Nanoparticles stabilized with nitrophenylboronic acid compositions
CN104856974A (en) * 2015-05-15 2015-08-26 海南圣欣医药科技有限公司 Poorly soluble antineoplastic drug micelle preparation and preparation method thereof

Also Published As

Publication number Publication date
WO2018008986A1 (en) 2018-01-11
CN109475498A (en) 2019-03-15
JP2019527351A (en) 2019-09-26
JP6810239B2 (en) 2021-01-06
KR20180005615A (en) 2018-01-16
KR101906321B1 (en) 2018-10-10
CN109475498B (en) 2021-04-02

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