PH10519A - 4-hydroxymethyl-1-phthalazone derivatives and pharmaceutical compositions thereof - Google Patents
4-hydroxymethyl-1-phthalazone derivatives and pharmaceutical compositions thereofInfo
- Publication number
- PH10519A PH10519A PH16465A PH16465A PH10519A PH 10519 A PH10519 A PH 10519A PH 16465 A PH16465 A PH 16465A PH 16465 A PH16465 A PH 16465A PH 10519 A PH10519 A PH 10519A
- Authority
- PH
- Philippines
- Prior art keywords
- hydroxymethyl
- pharmaceutical compositions
- phthalazone derivatives
- phthalazone
- derivatives
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/89—Benzo [c] furans; Hydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12126073A JPS5732065B2 (cs) | 1973-10-30 | 1973-10-30 | |
| JP12175773A JPS5724786B2 (cs) | 1973-10-31 | 1973-10-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH10519A true PH10519A (en) | 1977-05-26 |
Family
ID=26458679
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH16465A PH10519A (en) | 1973-10-30 | 1974-10-30 | 4-hydroxymethyl-1-phthalazone derivatives and pharmaceutical compositions thereof |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US3963716A (cs) |
| AR (1) | AR205004A1 (cs) |
| CA (1) | CA1029377A (cs) |
| CH (2) | CH610892A5 (cs) |
| DD (1) | DD119231A5 (cs) |
| DE (1) | DE2451417C3 (cs) |
| DK (1) | DK134345B (cs) |
| ES (1) | ES431454A1 (cs) |
| FI (1) | FI59402C (cs) |
| FR (1) | FR2248841B1 (cs) |
| GB (1) | GB1459606A (cs) |
| HU (1) | HU168797B (cs) |
| IE (1) | IE39831B1 (cs) |
| IL (1) | IL45675A (cs) |
| IN (1) | IN139552B (cs) |
| LU (1) | LU71191A1 (cs) |
| NL (1) | NL7414186A (cs) |
| PH (1) | PH10519A (cs) |
| SE (1) | SE412389B (cs) |
| YU (1) | YU289774A (cs) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4120960A (en) * | 1973-10-31 | 1978-10-17 | The Boots Company Limited | Therapeutic agents |
| NL7702763A (nl) * | 1976-03-18 | 1977-09-20 | Takio Shimamoto En Masayuki Is | Werkwijze voor de bereiding van thromboxaan- -antagonisten en van preparaten die deze stof- fen bevatten. |
| IE47592B1 (en) * | 1977-12-29 | 1984-05-02 | Ici Ltd | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture |
| US4293553A (en) * | 1978-08-11 | 1981-10-06 | Masayuki Ishikawa | 1-Phthalazone derivatives, and use thereof |
| US4464532A (en) * | 1979-07-31 | 1984-08-07 | Nippon Kayaku Kabushiki Kaisha | Intermediates of 7-alkoxycarbonyl-6,8-dimethyl-4-hydroxymethyl-1-phthalazone |
| JPS5668609A (en) * | 1979-11-07 | 1981-06-09 | Nippon Kayaku Co Ltd | Phthalazinol preparation |
| JPS58116471A (ja) * | 1981-12-29 | 1983-07-11 | Nippon Kayaku Co Ltd | ４−ヒドロキシメチル−１−フタラゾンエステル誘導体およびその塩 |
| GB2127805A (en) * | 1982-09-13 | 1984-04-18 | Showa Denko Kk | Phthalazones |
| US4861778A (en) * | 1986-06-16 | 1989-08-29 | Research Corporation | 2,3-dihydrophthalazine-1,4-diones |
| US5177075A (en) * | 1988-08-19 | 1993-01-05 | Warner-Lambert Company | Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process |
| DE68920798T2 (de) * | 1988-08-19 | 1995-05-18 | Warner Lambert Co | Substituierte Dihydroisochinolinone und verwandte Verbindungen als Verstärker der letalen Effekte von Bestrahlung und bestimmten Chemotherapeutika; ausgewählte Verbindungen, Analoga und Verfahren. |
| DE4345266C2 (de) * | 1993-10-04 | 1996-12-19 | Luitpold Pharma Gmbh | Heterocyclische Carbamate, Verfahren zu ihrer Herstellung und Arzneimittel |
| RU2169139C1 (ru) * | 2000-08-02 | 2001-06-20 | Закрытое акционерное общество "Центр современной медицины "Медикор" | Способ получения щелочных и щелочноземельных солей 5-амино-2,3-дигидро-1,4-фталазиндиона |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| AU2008261102B2 (en) | 2007-06-04 | 2013-11-28 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| JP2011522828A (ja) | 2008-06-04 | 2011-08-04 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
| WO2010009319A2 (en) | 2008-07-16 | 2010-01-21 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| ES2525748T3 (es) | 2009-11-13 | 2014-12-29 | Toray Industries, Inc. | Agente terapéutico o profiláctico para la diabetes |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| KR102034748B1 (ko) | 2011-03-01 | 2019-10-21 | 시너지 파마슈티컬즈 인코포레이티드 | 구아닐레이트 사이클라제 c 작용제의 제조 방법 |
| HK1218629A1 (zh) | 2013-02-25 | 2017-03-03 | Bausch Health Ireland Limited | 用於结肠清洁的鸟苷酸环化酶受体激动剂 |
| HK1220611A1 (zh) | 2013-03-15 | 2017-05-12 | Bausch Health Ireland Limited | 用於治療胃腸道病症的組成物 |
| EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| CN113388007A (zh) | 2013-06-05 | 2021-09-14 | 博士医疗爱尔兰有限公司 | 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法 |
| WO2015021358A2 (en) | 2013-08-09 | 2015-02-12 | Dominique Charmot | Compounds and methods for inhibiting phosphate transport |
| WO2020237096A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5116430B2 (cs) * | 1971-08-05 | 1976-05-24 | ||
| US3870792A (en) * | 1972-07-24 | 1975-03-11 | Michiro Inoue | Certain dihydrophthalizines for treating hemorrhage and thrombosis |
-
1974
- 1974-01-01 AR AR256326A patent/AR205004A1/es active
- 1974-09-03 IE IE1825/74A patent/IE39831B1/en unknown
- 1974-09-04 GB GB3870874A patent/GB1459606A/en not_active Expired
- 1974-09-10 US US05/504,745 patent/US3963716A/en not_active Expired - Lifetime
- 1974-09-16 IL IL45675A patent/IL45675A/xx unknown
- 1974-10-23 FR FR7435550A patent/FR2248841B1/fr not_active Expired
- 1974-10-24 CA CA212,163A patent/CA1029377A/en not_active Expired
- 1974-10-28 LU LU71191A patent/LU71191A1/xx unknown
- 1974-10-28 DK DK561874AA patent/DK134345B/da not_active IP Right Cessation
- 1974-10-28 SE SE7413530A patent/SE412389B/xx not_active IP Right Cessation
- 1974-10-29 YU YU02897/74A patent/YU289774A/xx unknown
- 1974-10-29 DE DE2451417A patent/DE2451417C3/de not_active Expired
- 1974-10-29 FI FI3157/74A patent/FI59402C/fi active
- 1974-10-29 ES ES431454A patent/ES431454A1/es not_active Expired
- 1974-10-29 HU HUIO218A patent/HU168797B/hu unknown
- 1974-10-30 NL NL7414186A patent/NL7414186A/xx not_active Application Discontinuation
- 1974-10-30 CH CH1454674A patent/CH610892A5/xx not_active IP Right Cessation
- 1974-10-30 PH PH16465A patent/PH10519A/en unknown
- 1974-10-30 DD DD182046A patent/DD119231A5/xx unknown
- 1974-10-30 CH CH497878A patent/CH611282A5/xx not_active IP Right Cessation
-
1976
- 1976-02-25 IN IN330/CAL/76A patent/IN139552B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2248841B1 (cs) | 1978-07-28 |
| ES431454A1 (es) | 1976-10-16 |
| IL45675A0 (en) | 1974-11-29 |
| AU7295474A (en) | 1976-03-11 |
| CA1029377A (en) | 1978-04-11 |
| DE2451417A1 (de) | 1975-05-07 |
| NL7414186A (nl) | 1975-05-02 |
| DK561874A (cs) | 1975-07-07 |
| SE7413530L (cs) | 1975-05-02 |
| IN139552B (cs) | 1976-07-03 |
| IE39831B1 (en) | 1979-01-03 |
| HU168797B (cs) | 1976-07-28 |
| DD119231A5 (cs) | 1976-04-12 |
| DE2451417C3 (de) | 1981-01-29 |
| YU289774A (en) | 1983-01-21 |
| DK134345B (da) | 1976-10-25 |
| DK134345C (cs) | 1977-03-21 |
| FI59402C (fi) | 1981-08-10 |
| LU71191A1 (cs) | 1975-04-17 |
| IE39831L (en) | 1975-04-30 |
| CH611282A5 (cs) | 1979-05-31 |
| SE412389B (sv) | 1980-03-03 |
| DE2451417B2 (de) | 1980-05-14 |
| IL45675A (en) | 1978-10-31 |
| AR205004A1 (es) | 1976-03-31 |
| US3963716A (en) | 1976-06-15 |
| FI315774A7 (cs) | 1975-05-01 |
| FR2248841A1 (cs) | 1975-05-23 |
| GB1459606A (en) | 1976-12-22 |
| FI59402B (fi) | 1981-04-30 |
| CH610892A5 (cs) | 1979-05-15 |
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