PE8898A1 - Procedimiento de obtencion de derivados 1,3-propanodiamina y compuestos intermedios - Google Patents
Procedimiento de obtencion de derivados 1,3-propanodiamina y compuestos intermediosInfo
- Publication number
- PE8898A1 PE8898A1 PE1996000516A PE00051696A PE8898A1 PE 8898 A1 PE8898 A1 PE 8898A1 PE 1996000516 A PE1996000516 A PE 1996000516A PE 00051696 A PE00051696 A PE 00051696A PE 8898 A1 PE8898 A1 PE 8898A1
- Authority
- PE
- Peru
- Prior art keywords
- procedure
- propanodiamine
- alkyl
- intermediate compounds
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
- C07C217/82—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring
- C07C217/84—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE REFIERE AL PROCEDIMIENTO DE PREPARACION DEL COMPUESTO DE FORMULA (B), QUE COMPRENDE: 1) HACER REACCIONAR Ra-NH2 CON (VII); 2) REDUCIR LA IMINA OBTENIDA EN (1); OPCIONALMENTE, 3) FORMAR UNA SAL DE ADICION DE ACIDO Y/O UN SOLVATO; EN LOS CUALES: "Ra" Y "Rd" SON INDEPENDIENTEMENTE, FENILO OPCIONALMENTE SUSTITUIDO CON 1; 2 o 3 RADICALES SELECCIONADOS DE: HALOGENO, -CF3, ALCOXI C1-C4, ALQUILO C1-C4, CN, OH, NITRO, NReRf o O2S-NReRf, EN DONDE: "Re" Y "Rf" SON INDEPENDIENTEMENTE, HIDROGENO O ALQUILO C1-C6, ENTRE OTROS; "Rc" ES H O ALQUILO C1-C4; "A" ES ALQUILENO C3; "B" ES ALQUILENO C1-C4; SIENDO EL COMPUESTO PREFERIBLEMENTE OBTENIDO EN TAL PROCEDIMIENTO EL HIDROCLORURO DE N-[2-(3,4 DIMETOXIFENIL) ETIL]-N-METIL-N`-(3,4 DIMETOXIFENIL) 1,3 PROPANODIAMINA. ADEMAS SE REFIERE A COMPUESTOS INTERMEDIOS EN LA OBTENCION DE (B), QUE COMPRENDEN: i) EL COMPUESTO DE FORMULA (VII), Y ii) LA IMINA OBTENIDA EN (1). LOS COMPUESTOS (B) POSEEN ACTIVIDAD CARDIOVASCULAR, EN PARTICULAR ACTIVIDAD ANTI-ANGINOSA
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9513756.8A GB9513756D0 (en) | 1995-07-06 | 1995-07-06 | Novel process & compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
PE8898A1 true PE8898A1 (es) | 1998-03-22 |
Family
ID=10777207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE1996000516A PE8898A1 (es) | 1995-07-06 | 1996-07-05 | Procedimiento de obtencion de derivados 1,3-propanodiamina y compuestos intermedios |
Country Status (11)
Country | Link |
---|---|
US (1) | US5973205A (es) |
EP (1) | EP0836589A1 (es) |
JP (1) | JPH11510482A (es) |
AU (1) | AU6656096A (es) |
CA (1) | CA2225672A1 (es) |
DZ (1) | DZ2064A1 (es) |
GB (1) | GB9513756D0 (es) |
MA (1) | MA23932A1 (es) |
PE (1) | PE8898A1 (es) |
WO (1) | WO1997002231A1 (es) |
ZA (1) | ZA965721B (es) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3707563A (en) * | 1970-09-14 | 1972-12-26 | Du Pont | Process for preparing n-alkylated aliphatic diamines |
GB8603765D0 (en) * | 1986-02-15 | 1986-03-19 | Beecham Wuelfung Gmbh & Co Kg | Compounds |
FR2702480B1 (fr) * | 1993-03-09 | 1995-04-28 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
ATE155125T1 (de) * | 1993-04-13 | 1997-07-15 | Duphar Int Res | Herstellung von dobutamin verbindungen |
-
1995
- 1995-07-06 GB GBGB9513756.8A patent/GB9513756D0/en active Pending
-
1996
- 1996-07-03 DZ DZ960108A patent/DZ2064A1/fr active
- 1996-07-04 MA MA24306A patent/MA23932A1/fr unknown
- 1996-07-05 PE PE1996000516A patent/PE8898A1/es not_active Application Discontinuation
- 1996-07-05 ZA ZA9605721A patent/ZA965721B/xx unknown
- 1996-07-08 US US08/981,812 patent/US5973205A/en not_active Expired - Fee Related
- 1996-07-08 JP JP9504839A patent/JPH11510482A/ja not_active Ceased
- 1996-07-08 EP EP96926333A patent/EP0836589A1/en not_active Withdrawn
- 1996-07-08 AU AU66560/96A patent/AU6656096A/en not_active Abandoned
- 1996-07-08 WO PCT/EP1996/002998 patent/WO1997002231A1/en not_active Application Discontinuation
- 1996-07-08 CA CA002225672A patent/CA2225672A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU6656096A (en) | 1997-02-05 |
MA23932A1 (fr) | 1997-04-01 |
JPH11510482A (ja) | 1999-09-14 |
CA2225672A1 (en) | 1997-01-23 |
US5973205A (en) | 1999-10-26 |
EP0836589A1 (en) | 1998-04-22 |
ZA965721B (en) | 1998-02-05 |
WO1997002231A1 (en) | 1997-01-23 |
GB9513756D0 (en) | 1995-09-06 |
DZ2064A1 (fr) | 2002-07-22 |
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Legal Events
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