PE62299A1 - THERAPEUTIC DERIVATIVES OF NAFTALENE - Google Patents

THERAPEUTIC DERIVATIVES OF NAFTALENE

Info

Publication number
PE62299A1
PE62299A1 PE00023098A PE00023098A PE62299A1 PE 62299 A1 PE62299 A1 PE 62299A1 PE 00023098 A PE00023098 A PE 00023098A PE 00023098 A PE00023098 A PE 00023098A PE 62299 A1 PE62299 A1 PE 62299A1
Authority
PE
Peru
Prior art keywords
6alkyl
hydrogen
6alkoxy
4alkyl
trifluoromethyl
Prior art date
Application number
PE00023098A
Other languages
Spanish (es)
Inventor
David Norman Deaton
Robert Blount Mcfadyen
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of PE62299A1 publication Critical patent/PE62299A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/68—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C229/70—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/47—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton having at least one of the sulfo groups bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system

Abstract

The invention relates to a compound of formula (I) wherein the groups N(R<3>) and R<4> are separated by at least 4 ring carbon atoms; R<1> represents a phenyl, naphthyl, phenoxymethyl, thiazolyl, pyridyl or pyrimidyl group, optionally substituted by one or more substituents selected from halogen, hydroxy, C1-6alkoxy, C1-6alkyl, nitro, cyano, hydroxymethyl, trifluoromethyl, NR<6>R<7>, and NHSO2R<6>; R<2> represents hydrogen or C1-6alkyl; R<3> represents hydrogen or C1-4alkyl; R<4> represents CO2R<6> or SO3H; R<5> represents one or more groups independently selected from hydrogen, C1-6alkyl, halogen, trifluoromethyl and C1-6alkoxy; n represents an integer from 1-6; R<6> and R<7> independently represent hydrogen or C1-4alkyl; or pharmaceutically acceptable derivatives thereof, to processes for their preparation and their use in the treatment of conditions susceptible of amelioration by an atypical beta-adrenoceptor agonist.
PE00023098A 1997-04-02 1998-03-27 THERAPEUTIC DERIVATIVES OF NAFTALENE PE62299A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9706707.8A GB9706707D0 (en) 1997-04-02 1997-04-02 Chemical compounds

Publications (1)

Publication Number Publication Date
PE62299A1 true PE62299A1 (en) 1999-07-07

Family

ID=10810177

Family Applications (1)

Application Number Title Priority Date Filing Date
PE00023098A PE62299A1 (en) 1997-04-02 1998-03-27 THERAPEUTIC DERIVATIVES OF NAFTALENE

Country Status (7)

Country Link
AR (1) AR012209A1 (en)
AU (1) AU7212598A (en)
GB (1) GB9706707D0 (en)
HR (1) HRP980171A2 (en)
MA (1) MA26478A1 (en)
PE (1) PE62299A1 (en)
WO (1) WO1998043953A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10326631A1 (en) * 2003-06-11 2005-01-05 Basf Ag Use of quinaldine and naphthalene derivatives as crystallization modifiers
EP1962838B1 (en) 2005-12-19 2011-09-28 GlaxoSmithKline LLC Farnesoid x receptor agonists
FR3041358B1 (en) * 2015-09-21 2017-11-24 Commissariat Energie Atomique ELECTROLYTE FOR ELECTROCHEMICAL GENERATOR

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO179246C (en) * 1991-11-20 1996-09-04 Sankyo Co Aromatic amino-alcohol derivatives and intermediates for their preparation
GB9313574D0 (en) * 1993-07-01 1993-08-18 Glaxo Group Ltd Medicaments
AU2737295A (en) * 1994-06-09 1996-01-04 Glaxo Group Limited Phenethanolamine derivatives and their use as atypical beta-adrenoceptor agonists

Also Published As

Publication number Publication date
WO1998043953A1 (en) 1998-10-08
AR012209A1 (en) 2000-09-27
AU7212598A (en) 1998-10-22
GB9706707D0 (en) 1997-05-21
MA26478A1 (en) 2004-12-20
HRP980171A2 (en) 1998-12-31

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