PE47399A1 - Cefalosporinas de vinil-pirrolidinona con sustituyentes basicos - Google Patents

Cefalosporinas de vinil-pirrolidinona con sustituyentes basicos

Info

Publication number
PE47399A1
PE47399A1 PE1997001116A PE00111697A PE47399A1 PE 47399 A1 PE47399 A1 PE 47399A1 PE 1997001116 A PE1997001116 A PE 1997001116A PE 00111697 A PE00111697 A PE 00111697A PE 47399 A1 PE47399 A1 PE 47399A1
Authority
PE
Peru
Prior art keywords
methyl
amino
omega
formula
alkyl
Prior art date
Application number
PE1997001116A
Other languages
English (en)
Inventor
Paul Hebeisen
Ingrid Heinze-Krauss
Malcolm Page
Peter Angehrn
Valerie Runtz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PE47399A1 publication Critical patent/PE47399A1/es

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Cephalosporin Compounds (AREA)

Abstract

SE REFIEREN A COMPUESTOS DE FORMULA (I), EN DONDE: "X" ES CH o N; R1 ES H o CICLOPENTILO; R2 ES HETEROCICLO DE 4 A 6 MIEMBROS QUE CONTIENE 1 o 2 NITROGENOS COMO LOS RADICALES DE FORMULA (a) Y (b) Y ESTAN OPCIONALMENTE SUSTITUIDOS POR GRUPOS R4, R5 Y R6, CH2-C(=NH)NHR4, CH2-CH2-NR4R7, EN DONDE: R3 ES H, UN METAL ALCALINO o UN GRUPO AMINO TERCIARIO; R4 ES H, UN GRUPO PROTECTOR AMINO, PIRROLIDIN-2-IL-METILO, AZETIDIN-3-IL-METILO, IMINOMETILO, 1-CARBAMIMIDOILO; R5 ES H, DIALQUILCARBAMOILO, OMEGA-HIDROXIALQUILO, OMEGA-AMINOALQUILO, PIRIDINIO-1-ILMETILO, 1-HIDROXI-3-AMINOMETIL-PROPILO o HIDROXI-(PIRROLIDIN-2-IL)-METILO; R6 ES H, CF3 o OH; R7 ES ALQUILO, OMEGA-HIDROXI-ALQUILO, CICLOALQUILO, 3-PIRROLIDINILO, 3-AZETIDINILO, IMINOMETILO o 1-CARBAMIMIDOILO. TAMBIEN SE REFIERE AL PROCEDIMIENTO DE PREPARACION DE (I) Y A LOS COMPUESTOS INTERMEDIOS EN SU PREPARACION, SIENDO UN COMPUESTO INTERMEDIO PREFERIDO EL ESTER DE S-BENZOTIAZOL-2-ILO DEL ACIDO (Z)-(5-AMINO-[1,2,4]TIADIAZOL-3-IL)-TRITILOXIIMINO-TIOACETICO. LOS COMPUESTOS DE FORMULA (I) PUEDEN SER UTILES COMO ANTIBIOTICOS QUE TIENEN ACTIVIDAD ANTIBACTERIANA POTENTE Y AMPLIA ESPECIALMENTE CONTRA STAPHYLOCOCCUS AUREUS RESISTENTES A METICILINA (MRSA) Y PSEUDOMONAS AERUGINOSA RESISTENTES A METICILINA
PE1997001116A 1996-12-19 1997-12-12 Cefalosporinas de vinil-pirrolidinona con sustituyentes basicos PE47399A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96120472 1996-12-19

Publications (1)

Publication Number Publication Date
PE47399A1 true PE47399A1 (es) 1999-05-14

Family

ID=8223516

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1997001116A PE47399A1 (es) 1996-12-19 1997-12-12 Cefalosporinas de vinil-pirrolidinona con sustituyentes basicos

Country Status (11)

Country Link
AR (1) AR009669A1 (es)
BR (1) BRPI9705650B8 (es)
CO (1) CO4930271A1 (es)
HR (1) HRP970691A2 (es)
ID (1) ID19269A (es)
PE (1) PE47399A1 (es)
PL (1) PL323854A1 (es)
TR (1) TR199701643A3 (es)
UY (1) UY24814A1 (es)
YU (1) YU48197A (es)
ZA (1) ZA9711214B (es)

Also Published As

Publication number Publication date
TR199701643A2 (xx) 1998-07-21
ID19269A (id) 1998-06-28
BRPI9705650B1 (pt) 2011-06-28
PL323854A1 (en) 1998-06-22
MX9710004A (es) 1998-09-30
TR199701643A3 (tr) 1998-07-21
BRPI9705650A (pt) 1999-05-25
UY24814A1 (es) 2000-12-29
ZA9711214B (en) 1998-06-19
HRP970691A2 (en) 1998-10-31
CO4930271A1 (es) 2000-06-27
AR009669A1 (es) 2000-04-26
BRPI9705650B8 (pt) 2021-07-06
YU48197A (sh) 2000-10-30

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Legal Events

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