PE20161173A1 - Formulaciones topicas de la heparina - Google Patents
Formulaciones topicas de la heparinaInfo
- Publication number
- PE20161173A1 PE20161173A1 PE2016001445A PE2016001445A PE20161173A1 PE 20161173 A1 PE20161173 A1 PE 20161173A1 PE 2016001445 A PE2016001445 A PE 2016001445A PE 2016001445 A PE2016001445 A PE 2016001445A PE 20161173 A1 PE20161173 A1 PE 20161173A1
- Authority
- PE
- Peru
- Prior art keywords
- heparin
- pharmaceutically acceptable
- formulation
- water
- acceptable salts
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se refiere a una formulacion topica de sales farmaceuticamente aceptables de la heparina que comprende: a) 50 a 2500 UI/mL de sales farmaceuticamente aceptables de la heparina; b) menos de o equivalente a 30 % v/v de agua, c) 10 % a 30 % v/v de una cadena de alcohol inferior; y d) un vehiculo miscible en agua tal como propilenglicol, glicerol, glicofurol, polietilenglicoles u otras mezclas del mismo. Asimismo, dicha formulacion contiene excipientes farmaceuticamente aceptables tales como preservantes, antioxidantes, estabilizantes, entre otros. Dicha formulacion se caracteriza por una excelente penetracion transdermica y efectividad terapeutica mejorada cuando se aplica de manera topica en condiciones tal como tromboflebitis venosa superficial
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN475MU2014 | 2014-02-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20161173A1 true PE20161173A1 (es) | 2016-10-27 |
Family
ID=52684592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2016001445A PE20161173A1 (es) | 2014-02-10 | 2015-02-10 | Formulaciones topicas de la heparina |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US9861655B2 (es) |
| EP (1) | EP3104839B1 (es) |
| JP (1) | JP6275877B2 (es) |
| KR (1) | KR101822133B1 (es) |
| CN (1) | CN106163498A (es) |
| AP (1) | AP2016009350A0 (es) |
| AR (1) | AR099333A1 (es) |
| AU (1) | AU2015213569B2 (es) |
| CA (1) | CA2938388C (es) |
| CL (1) | CL2016001952A1 (es) |
| CU (1) | CU24444B1 (es) |
| DK (1) | DK3104839T3 (es) |
| DO (1) | DOP2016000198A (es) |
| EA (1) | EA032200B1 (es) |
| EC (1) | ECSP16069947A (es) |
| IL (1) | IL246974B (es) |
| MA (1) | MA39304B1 (es) |
| MX (1) | MX357765B (es) |
| MY (1) | MY182620A (es) |
| NZ (1) | NZ722830A (es) |
| PE (1) | PE20161173A1 (es) |
| PH (1) | PH12016501500A1 (es) |
| TW (1) | TWI538697B (es) |
| UA (1) | UA118279C2 (es) |
| WO (1) | WO2015118512A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103491778B (zh) * | 2010-04-13 | 2017-05-31 | 雷尔玛达治疗股份有限公司 | 1‑甲基‑n‑(2，6‑二甲苯基)‑2‑哌啶甲酰胺的皮肤用药物组合物及其使用方法 |
| CN112546061B (zh) * | 2021-02-25 | 2021-06-11 | 中南大学湘雅医院 | 一种肝素类药物组合物、喷鼻剂及其制备方法及应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3323389A1 (de) * | 1983-06-29 | 1985-01-10 | B. Braun Melsungen Ag, 3508 Melsungen | Auf schleimhaeute des mundes, der nase und/oder des rachens wirkende arzneimittel auf der basis von heparin und tensiden |
| JPH02207018A (ja) * | 1989-02-07 | 1990-08-16 | Kao Corp | 皮膚外用剤 |
| ES2180599T3 (es) | 1994-09-30 | 2003-02-16 | Mika Pharma Ges Fur Die Entwic | Composicion farmaceutica. |
| IT1275955B1 (it) | 1995-03-22 | 1997-10-24 | Dompe Spa | Formulazioni farmaceutiche in forma di gel tissotropico |
| JPH10279466A (ja) * | 1997-04-07 | 1998-10-20 | Kose Corp | 外用剤 |
| US6761903B2 (en) | 1999-06-30 | 2004-07-13 | Lipocine, Inc. | Clear oil-containing pharmaceutical compositions containing a therapeutic agent |
| BRPI0101486B1 (pt) | 2001-04-17 | 2017-09-19 | Cristália Produtos Químicos Farmacêuticos Ltda. | Pharmaceutical composition for topic use containing heparin for the treatment of skin or mucosal injuries caused by burns |
| RU2467759C2 (ru) * | 2006-11-15 | 2012-11-27 | Артрайтис Рилиф Плас Лтд | Состав для местного использования и его применения |
| IT1400232B1 (it) * | 2010-05-07 | 2013-05-24 | Advance Holdings Ltd | Composizione farmaceutica topica comprendente eparina |
| RU2013147883A (ru) * | 2011-04-01 | 2015-05-10 | Юниверсити Оф Флорида Рисеч Фаундэйшн, Инк. | Термочувствительные, мукоадгезивные или кожно-адгезивные и усиливающие проникновение композиции для местной доставки терапевтических средств |
-
2015
- 2015-02-10 EA EA201691596A patent/EA032200B1/ru unknown
- 2015-02-10 JP JP2016568157A patent/JP6275877B2/ja active Active
- 2015-02-10 UA UAA201608842A patent/UA118279C2/uk unknown
- 2015-02-10 CA CA2938388A patent/CA2938388C/en active Active
- 2015-02-10 AP AP2016009350A patent/AP2016009350A0/en unknown
- 2015-02-10 CN CN201580007796.6A patent/CN106163498A/zh active Pending
- 2015-02-10 AU AU2015213569A patent/AU2015213569B2/en active Active
- 2015-02-10 WO PCT/IB2015/050986 patent/WO2015118512A1/en active Application Filing
- 2015-02-10 TW TW104104460A patent/TWI538697B/zh not_active IP Right Cessation
- 2015-02-10 EP EP15710252.6A patent/EP3104839B1/en active Active
- 2015-02-10 DK DK15710252.6T patent/DK3104839T3/da active
- 2015-02-10 MY MYPI2016702732A patent/MY182620A/en unknown
- 2015-02-10 NZ NZ722830A patent/NZ722830A/en unknown
- 2015-02-10 MA MA39304A patent/MA39304B1/fr unknown
- 2015-02-10 AR ARP150100384A patent/AR099333A1/es unknown
- 2015-02-10 KR KR1020167023895A patent/KR101822133B1/ko active IP Right Grant
- 2015-02-10 MX MX2016010399A patent/MX357765B/es active IP Right Grant
- 2015-02-10 US US15/116,060 patent/US9861655B2/en not_active Expired - Fee Related
- 2015-02-10 CU CU2016000119A patent/CU24444B1/es unknown
- 2015-02-10 PE PE2016001445A patent/PE20161173A1/es unknown
-
2016
- 2016-07-27 IL IL246974A patent/IL246974B/en active IP Right Grant
- 2016-07-28 PH PH12016501500A patent/PH12016501500A1/en unknown
- 2016-08-02 CL CL2016001952A patent/CL2016001952A1/es unknown
- 2016-08-03 DO DO2016000198A patent/DOP2016000198A/es unknown
- 2016-08-26 EC ECIEPI201669947A patent/ECSP16069947A/es unknown
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