PE20091345A1 - Arilindenopirimidinas como antagonistas del receptor a2a de adenosina - Google Patents
Arilindenopirimidinas como antagonistas del receptor a2a de adenosinaInfo
- Publication number
- PE20091345A1 PE20091345A1 PE2008001825A PE2008001825A PE20091345A1 PE 20091345 A1 PE20091345 A1 PE 20091345A1 PE 2008001825 A PE2008001825 A PE 2008001825A PE 2008001825 A PE2008001825 A PE 2008001825A PE 20091345 A1 PE20091345 A1 PE 20091345A1
- Authority
- PE
- Peru
- Prior art keywords
- disease
- adenosine
- antagonists
- arylindenopyrimidines
- receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
REFERIDO A UN COMPUESTO DE FORMULAS A, B O C, SOLVATOS, HIDRATOS, TAUTOMEROS Y SALES FARMACEUTICAS ACEPTABLES DE ESTOS. SE REFIERE TAMBIEN A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON ANTAGONISTAS DE LOS RECEPTORES DE ADENOSINA A2A, SIENDO UTILES PARA EL TRATAMIENTO DE ENFERMEDAD DE PARKINSON, MAL DE HUNTINGTON, ATROFIA SISTEMICA MULTIPLE, DEGENERACION CORTICOBASAL, ENFERMEDAD DE ALZHEIMER Y DEMENCIA SENIL, ENTRE OTROS
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98245607P | 2007-10-25 | 2007-10-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20091345A1 true PE20091345A1 (es) | 2009-09-24 |
Family
ID=40225283
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2008001825A PE20091345A1 (es) | 2007-10-25 | 2008-10-24 | Arilindenopirimidinas como antagonistas del receptor a2a de adenosina |
Country Status (13)
Country | Link |
---|---|
US (1) | US20090111804A1 (es) |
EP (1) | EP2220053B1 (es) |
JP (1) | JP2011500833A (es) |
CN (1) | CN101835760A (es) |
AR (1) | AR069026A1 (es) |
AT (1) | ATE509012T1 (es) |
AU (1) | AU2008316821A1 (es) |
CL (1) | CL2008003184A1 (es) |
PA (1) | PA8801401A1 (es) |
PE (1) | PE20091345A1 (es) |
TW (1) | TW200934496A (es) |
UY (1) | UY31421A1 (es) |
WO (1) | WO2009055548A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110105540A1 (en) * | 2009-10-29 | 2011-05-05 | Jackson Paul F | 2-AMINO-9-[4-(4-METHOXY-PHENOXY)-PIPERIDIN-1-YL]-4-PHENYL-INDENO[1,2-D]PYRIMIDIN-5-ONE AND ITS USE AS A HIGHLY SELECTIVE ADENOSINE A2a RECEPTOR ANTAGONIST |
WO2011101861A1 (en) | 2010-01-29 | 2011-08-25 | Msn Laboratories Limited | Process for preparation of dpp-iv inhibitors |
WO2023201267A1 (en) | 2022-04-13 | 2023-10-19 | Gilead Sciences, Inc. | Combination therapy for treating trop-2 expressing cancers |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19627430A1 (de) * | 1996-07-08 | 1998-01-15 | Bayer Ag | Bicyclisch kondensierte Pyridine |
US5939432A (en) * | 1997-10-29 | 1999-08-17 | Medco Research, Inc. | Thiophenes useful for modulating the adenosine receptor |
ES2170446T3 (es) * | 1997-12-05 | 2002-08-01 | Hoffmann La Roche | Derivados de 1,3,8-triaza-espiro(4,5)decan-4-ona. |
US20040127510A1 (en) * | 2002-04-16 | 2004-07-01 | Heintzelman Geoffrey R. | Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods |
RS20060237A (en) * | 2003-10-03 | 2008-11-28 | Ortho-Mcneil Pharmaceutical Inc., | Arylindenopyridines and arylindenopyridines and their use as adenosine a2a receptor antagonist |
-
2008
- 2008-10-22 PA PA20088801401A patent/PA8801401A1/es unknown
- 2008-10-23 JP JP2010531235A patent/JP2011500833A/ja not_active Withdrawn
- 2008-10-23 WO PCT/US2008/080923 patent/WO2009055548A1/en active Application Filing
- 2008-10-23 AU AU2008316821A patent/AU2008316821A1/en not_active Abandoned
- 2008-10-23 EP EP08841729A patent/EP2220053B1/en not_active Not-in-force
- 2008-10-23 US US12/256,898 patent/US20090111804A1/en not_active Abandoned
- 2008-10-23 AT AT08841729T patent/ATE509012T1/de not_active IP Right Cessation
- 2008-10-23 CN CN200880113362A patent/CN101835760A/zh active Pending
- 2008-10-24 TW TW097140753A patent/TW200934496A/zh unknown
- 2008-10-24 CL CL2008003184A patent/CL2008003184A1/es unknown
- 2008-10-24 UY UY31421A patent/UY31421A1/es unknown
- 2008-10-24 PE PE2008001825A patent/PE20091345A1/es not_active Application Discontinuation
- 2008-10-24 AR ARP080104647A patent/AR069026A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
JP2011500833A (ja) | 2011-01-06 |
AU2008316821A1 (en) | 2009-04-30 |
AR069026A1 (es) | 2009-12-23 |
TW200934496A (en) | 2009-08-16 |
PA8801401A1 (es) | 2009-05-15 |
UY31421A1 (es) | 2009-04-30 |
CN101835760A (zh) | 2010-09-15 |
WO2009055548A1 (en) | 2009-04-30 |
EP2220053B1 (en) | 2011-05-11 |
ATE509012T1 (de) | 2011-05-15 |
EP2220053A1 (en) | 2010-08-25 |
CL2008003184A1 (es) | 2009-10-16 |
US20090111804A1 (en) | 2009-04-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application declared void or lapsed |