PE20040557A1 - 2-HETEROARYLCARBOXYL ACIDS AMIDES - Google Patents
2-HETEROARYLCARBOXYL ACIDS AMIDESInfo
- Publication number
- PE20040557A1 PE20040557A1 PE2003000576A PE2003000576A PE20040557A1 PE 20040557 A1 PE20040557 A1 PE 20040557A1 PE 2003000576 A PE2003000576 A PE 2003000576A PE 2003000576 A PE2003000576 A PE 2003000576A PE 20040557 A1 PE20040557 A1 PE 20040557A1
- Authority
- PE
- Peru
- Prior art keywords
- oct
- benzofuran
- carboxamide
- halogen
- phenyl
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
SE REFIERE A UN COMPUESTO DE FORMULA I DONDE R1 ES 1-AZA-BICICLO[2.2.2]OCT-3-ILO SUSTITUIDO A TRAVES DEL NITROGENO POR ALQUILO C1-C4, BENCILO Y OXI; R2 ES H, ALQUILO C1-C6; R3 ES H, HALOGENO, ALQUILO C1-C6; R4 ES H, HALOGENO, CIANO, AMINO, ENTRE OTROS; A ES O, S; B ES ANILLO BENZO O PIRIDO SUSTITUIDOS POR HALOGENO, CIANO, FORMILO, ENTRE OTROS; E ES ETINILO, ARILO, HETEROARILO, ENTRE OTROS. SON COMPUESTOS PREFERIDOS: N-[(3R)-1-AZABICICLO[2.2.2]OCT-3-IL]-6-[2-(HIDROXIMETIL)FENIL]-1-BENZOFURAN-2-CARBOXAMIDA; N-[(3R)-1-AZABICICLO[2.2.2]OCT-3-IL]-6-[3-(HIDROXIMETIL)FENIL]-1-BENZOFURAN-2-CARBOXAMIDA Y N-[(3R)-1-AZABICICLO[2.2.2]OCT-3-IL]-6-[4-(4-MORFOLINIL)FENIL]-1-BENZOFURAN-2-CARBOXAMIDA. SE REFIERE TAMBIEN A UN PROCEDIMIENTODE PREPARACION DE DICHOS COMPUESTOS, LOS QUE SON UTILES EN EL TRATAMIENTO Y/O PROFILAXIS DE TRASTORNOS DE LA CAPACIDAD PERCEPTIVA, LA CAPACIDAD DE CONCENTRACION, APRENDIZAJE Y/O MEMORIAIT REFERS TO A COMPOUND OF FORMULA I WHERE R1 IS 1-AZA-BICYCLE [2.2.2] OCT-3-ILO SUBSTITUTED THROUGH NITROGEN BY C1-C4 ALKYL, BENZYL AND OXY; R2 IS H, C1-C6 ALKYL; R3 IS H, HALOGEN, C1-C6 ALKYL; R4 IS H, HALOGEN, CYANE, AMINO, AMONG OTHERS; A IS O, S; B IS BENZO OR PIRIDO RING REPLACED BY HALOGEN, CYANE, FORMIL, AMONG OTHERS; E IS ETHINYL, ARYL, HETEROARYL, AMONG OTHERS. PREFERRED COMPOUNDS ARE: N - [(3R) -1-AZABICYCLE [2.2.2] OCT-3-IL] -6- [2- (HYDROXIMETHYL) PHENYL] -1-BENZOFURAN-2-CARBOXAMIDE; N - [(3R) -1-AZABICYCLO [2.2.2] OCT-3-IL] -6- [3- (HYDROXIMETHYL) PHENYL] -1-BENZOFURAN-2-CARBOXAMIDE AND N - [(3R) -1- AZABICYCLO [2.2.2] OCT-3-IL] -6- [4- (4-MORPHOLINYL) PHENYL] -1-BENZOFURAN-2-CARBOXAMIDE. IT ALSO REFERS TO A PROCEDURE FOR THE PREPARATION OF SUCH COMPOUNDS, THOSE THAT ARE USEFUL IN THE TREATMENT AND / OR PROPHYLAXIS OF DISORDERS OF PERCEPTIVE ABILITY, THE ABILITY TO CONCENTRATION, LEARNING AND / OR MEMORY
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10225536 | 2002-06-10 | ||
DE10257078A DE10257078A1 (en) | 2002-12-06 | 2002-12-06 | New N-azabicyclooctyl bicyclic heteroaryl carboxamides, are alpha 7-nicotinic acetylcholine receptor ligands useful for improving attention, concentration, learning and/or memory performance |
DE2002157537 DE10257537A1 (en) | 2002-12-10 | 2002-12-10 | New N-azabicyclooctyl bicyclic heteroaryl carboxamides, are alpha 7-nicotinic acetylcholine receptor ligands useful for improving attention, concentration, learning and/or memory performance |
DE10305922A DE10305922A1 (en) | 2002-06-10 | 2003-02-13 | New N-azabicyclooctyl bicyclic heteroaryl carboxamides, are alpha 7-nicotinic acetylcholine receptor ligands useful for improving attention, concentration, learning and/or memory performance |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20040557A1 true PE20040557A1 (en) | 2004-10-01 |
Family
ID=41259016
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2003000576A PE20040557A1 (en) | 2002-06-10 | 2003-06-10 | 2-HETEROARYLCARBOXYL ACIDS AMIDES |
Country Status (6)
Country | Link |
---|---|
AR (1) | AR040261A1 (en) |
DO (1) | DOP2003000657A (en) |
HN (1) | HN2003000166A (en) |
HR (1) | HRP20050012A2 (en) |
PE (1) | PE20040557A1 (en) |
TW (1) | TW200410967A (en) |
-
2003
- 2003-06-09 TW TW92115481A patent/TW200410967A/en unknown
- 2003-06-09 DO DO2003000657A patent/DOP2003000657A/en unknown
- 2003-06-09 HN HN2003000166A patent/HN2003000166A/en unknown
- 2003-06-10 AR ARP030102069 patent/AR040261A1/en unknown
- 2003-06-10 PE PE2003000576A patent/PE20040557A1/en not_active Application Discontinuation
-
2005
- 2005-01-07 HR HR20050012A patent/HRP20050012A2/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AR040261A1 (en) | 2005-03-23 |
HRP20050012A2 (en) | 2006-04-30 |
HN2003000166A (en) | 2004-07-27 |
TW200410967A (en) | 2004-07-01 |
DOP2003000657A (en) | 2004-01-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PE20060777A1 (en) | INDOLINONE DERIVATIVES FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES | |
PE20070218A1 (en) | AMINO-HYDANTOIN CYCLOALKYL COMPOUNDS AND USE OF THESE FOR THE MODULATION OF ß-SECRETASE | |
CO4960641A1 (en) | DERIVATIVES OF PIPERIDINE 1,4-DISSTITUTED CONTAINING FLUORINE | |
PE20050132A1 (en) | SUBSTITUTED HETEROCYCLIC PIPERAZINES | |
PE20060243A1 (en) | DERIVATIVES OF 4-AMINO INSUSTITUTED-5- (4-UREA-PHENYL) -PYRROLOTRIAZINE | |
PE20040155A1 (en) | AMINOINAZOLE DERIVATIVES, PREPARATION PROCEDURE AND INTERMEDIATES OF THIS PROCEDURE AS A DRUGS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | |
PE20061106A1 (en) | DERIVATIVES OF 2- (4-OXO-4H-QUINAZOLIN-3-IL) ACETAMIDE | |
CR8505A (en) | DERIVATIVES OF (3-OXO-3,4-DIHIDROQUINOXALIN-2-IL-AMINO) -BENZAMIDE AND RELATED COMPOUND, AS INHIBITORS OF GLUCOGENO FOSFORILASA FOR THE TREATMENT OF DIABETES AND OBESITY | |
AR006720A1 (en) | A COMPOUND DERIVED FROM HETERO-CYCLIC AZAHEXANE, ITS USE FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION, PROCEDURE FOR PREPARING IT AND A PHARMACEUTICAL COMPOSITION THAT INCLUDES IT | |
PE20050131A1 (en) | BENZOIMIDAZOLE DERIVATIVES AS ANTIPROLIFERATIVE AGENTS | |
FI943247A (en) | Piperazine derivatives as 5-HT receptor antagonists | |
DK526188A (en) | BENZIMIDAZOLINE-2-OXO-1-CARBOXYLIC ACID DERIVATIVES FOR USE AS 5-HT RECEPTOR ANTAGONISTS IN PHARMACEUTICAL PREPARATIONS | |
PE20040667A1 (en) | CINAMIDE DERIVATIVES | |
ATE540928T1 (en) | ISOQUINOLINE COMPOUNDS AND THEIR MEDICAL USES | |
PE20020103A1 (en) | DERIVATIVES OF 1-SULFONYL-PYRROLIDINE | |
NO20025641D0 (en) | Substituted 1-aminoalkyl lactams and their use as muscarinic receptor antagonists | |
DE3868301D1 (en) | 2- (METHYL (4-PIPERIDINYL)) - 1,2,3,4-TETRAHYDRO-9H-PYRIDO (3,4-B) INDOLE DERIVATIVES, THEIR PRODUCTION AND THERAPEUTIC USE. | |
MA30756B1 (en) | CINNAMOYL-PIPERAZINE DERIVATIVES AND THEIR USE AS ANTAGONISTS BY-1 | |
NO941884L (en) | 1,3-substituted cycloalkenes and cycloalkanes as central nervous system agents | |
HK1076107A1 (en) | Pyrrolidine derivatives as oxytocin antagonists | |
PE20030761A1 (en) | DERIVATIVES OF 7-AMINO-BENZOTHIAZOLE | |
PE20040531A1 (en) | DERIVATIVES OF ISOINDOLONE, PREPARATION PROCESS, INTERMEDIATE COMPOUNDS OF THIS PROCESS AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM | |
PE20030763A1 (en) | HIV INTEGRASE INHIBITORS | |
PA8575001A1 (en) | FLUOROBENZAMIDS AS MAOB INHIBITORS | |
AR039122A1 (en) | FTALIMIDE DERIVATIVES AS INHIBITORS OF MONOAMINO OXIDASA B |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant, registration | ||
FD | Application declared void or lapsed |