PE20010331A1 - Una combinacion sinergetica: gabapentina y pregabalina - Google Patents

Una combinacion sinergetica: gabapentina y pregabalina

Info

Publication number
PE20010331A1
PE20010331A1 PE2000000651A PE0006512000A PE20010331A1 PE 20010331 A1 PE20010331 A1 PE 20010331A1 PE 2000000651 A PE2000000651 A PE 2000000651A PE 0006512000 A PE0006512000 A PE 0006512000A PE 20010331 A1 PE20010331 A1 PE 20010331A1
Authority
PE
Peru
Prior art keywords
pregabalin
gabapentin
synergy combination
ratio
pharmaceutical composition
Prior art date
Application number
PE2000000651A
Other languages
English (en)
Inventor
Roger N Brummel
Lakhbir Singh
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of PE20010331A1 publication Critical patent/PE20010331A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA DE EFECTO SINERGICO QUE COMPRENDE a) GABAPENTINA (ACIDO 1-(AMINOMETIL)-CICLOHEXANACETICO) EN FORMA DE ACIDO LIBRE EN UNA PROPORCION DE 1:1000, UTILIZANDOSE 5 mg A 250 mg; b)PREGABALINA ((S)-3-(AMINOMETIL)-5-METILHEXANOICO) EN FORMA DE ACIDO LIBRE EN UNA PROPORCION DE 1:1000, UTILIZANDOSE 5 mg A 25 mg. LA COMPOSICION FARMACEUTICA PUEDE SER UTIL PARA EL TRATAMIENTO DEL DOLOR AGUDO Y CRONICO
PE2000000651A 1999-07-02 2000-06-28 Una combinacion sinergetica: gabapentina y pregabalina PE20010331A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14221599P 1999-07-02 1999-07-02

Publications (1)

Publication Number Publication Date
PE20010331A1 true PE20010331A1 (es) 2001-03-22

Family

ID=22499016

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2000000651A PE20010331A1 (es) 1999-07-02 2000-06-28 Una combinacion sinergetica: gabapentina y pregabalina

Country Status (14)

Country Link
EP (1) EP1196160B1 (es)
JP (1) JP2003503453A (es)
AR (1) AR030024A1 (es)
AT (1) ATE313322T1 (es)
AU (1) AU5753900A (es)
BR (1) BR0012058A (es)
CA (1) CA2373953A1 (es)
CO (1) CO5210869A1 (es)
DE (1) DE60024995T2 (es)
ES (1) ES2255500T3 (es)
MX (1) MXPA02000170A (es)
PE (1) PE20010331A1 (es)
UY (1) UY26230A1 (es)
WO (1) WO2001001983A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998003167A1 (en) 1996-07-24 1998-01-29 Warner-Lambert Company Isobutylgaba and its derivatives for the treatment of pain
JP4428053B2 (ja) * 2002-02-05 2010-03-10 味の素株式会社 ガバペンチン若しくはプレガバリンおよびｎ型カルシウムチャンネル拮抗剤を含有する医薬組成物
US7687080B2 (en) * 2002-11-25 2010-03-30 Taraxos Inc. Treatment of neuropathy
WO2004084881A1 (en) * 2003-03-21 2004-10-07 Dynogen Pharmaceuticals, Inc. METHODS FOR TREATING FUNCTIONAL BOWEL DISORDERS USING α2δ SUBUNIT CALCIUM CHANNEL MODULATORS WITH SMOOTH MUSCLE MODULATORS
WO2004084880A1 (en) * 2003-03-21 2004-10-07 Dynogen Pharmaceuticals, Inc. METHODS FOR TREATING PAIN USING SMOOTH MUSCLE MODULATORS AND α2δ SUBUNIT CALCIUM CHANNEL MODULATORS
ATE345120T1 (de) * 2003-03-21 2006-12-15 Dynogen Pharmaceuticals Inc Verfahren zur behandlung von erkrankungen der unteren harnwege mit antimuskarinika und mit modulatoren der alpha-2-delta untereinheit des kalziumkanals
JP2005060311A (ja) * 2003-08-13 2005-03-10 Mochida Pharmaceut Co Ltd Ｎ−（ベンゾイル）アミノ酸誘導体を有効成分とするニューロパシー性疼痛治療剤
DE102007019071A1 (de) * 2007-04-23 2008-10-30 Ratiopharm Gmbh Stabilisierte pharmazeutische Zusammensetzung enthaltend Pregabalin
AU2009296457A1 (en) 2008-09-27 2010-04-01 Taraxos Inc. Topical formulations for treatment of neuropathy
WO2010115612A2 (en) * 2009-04-10 2010-10-14 Synthon B.V. Pregabalin compositions
AU2010325925B2 (en) 2009-12-04 2016-02-25 Pgi Drug Discovery Llc. Multicyclic compounds and methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU9019198A (en) * 1997-08-19 1999-03-08 Warner-Lambert Company Methods for treating physiological conditions associated with the use, or sequelae of use, of cocaine or other psychomotor stimulants
DE19802327A1 (de) * 1998-01-23 1999-07-29 Goedecke Ag Synergistische Arzneimittelzubereitung mit analgetischer Wirkung
WO2000053225A1 (en) * 1999-03-10 2000-09-14 Warner-Lambert Company Analgesic compositions comprising anti-epileptic compounds and methods of using same

Also Published As

Publication number Publication date
DE60024995T2 (de) 2006-06-22
ATE313322T1 (de) 2006-01-15
JP2003503453A (ja) 2003-01-28
MXPA02000170A (es) 2002-07-02
AR030024A1 (es) 2003-08-13
EP1196160A1 (en) 2002-04-17
UY26230A1 (es) 2001-03-16
WO2001001983A1 (en) 2001-01-11
EP1196160B1 (en) 2005-12-21
DE60024995D1 (de) 2006-01-26
BR0012058A (pt) 2002-05-14
CA2373953A1 (en) 2001-01-11
AU5753900A (en) 2001-01-22
ES2255500T3 (es) 2006-07-01
CO5210869A1 (es) 2002-10-30

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Legal Events

Date Code Title Description
FG Grant, registration
FD Application declared void or lapsed