PE20001370A1 - Proceso para recuperar antibioticos oligosacaridos lipofilicos - Google Patents
Proceso para recuperar antibioticos oligosacaridos lipofilicosInfo
- Publication number
- PE20001370A1 PE20001370A1 PE1999001277A PE00127799A PE20001370A1 PE 20001370 A1 PE20001370 A1 PE 20001370A1 PE 1999001277 A PE1999001277 A PE 1999001277A PE 00127799 A PE00127799 A PE 00127799A PE 20001370 A1 PE20001370 A1 PE 20001370A1
- Authority
- PE
- Peru
- Prior art keywords
- antibiotic
- broth
- adsorbent
- alkyl
- recover
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
SE REFIERE A UN PROCESO PARA RECUPERAR UN ANTIBIOTICO OLIGOSACARIDO LIPOFILICO (ORTOSOMICINAS) A PARTIR DE UN CALDO DE FERMENTACION ACUOSA QUE CONTIENE EL ANTIBIOTICO MEZCLADO CON IMPUREZAS, DERIVADOS O SOLIDOS SUSPENDIDOS; QUE COMPRENDE a)COMBINAR EL CALDO DE FERMENTACION CON UN ADSORBENTE, SIENDO EL CALDO PRETRATADO POR SEPARACION DE LOS SOLIDOS SUSPENDIDOS, SIENDO EL ADSORBENTE UN MATERIAL INSOLUBLE COMO UN POLIMERO QUE COMPRENDE UNA MATRIZ POLIMERICA NO IONICA; b)AJUSTAR EL pH DEL CALDO A ALCALINO ENTRE 9 Y 11, A FIN DE SOLUBILIZAR EL ANTIBIOTICO EN EL CALDO; c)DAR TIEMPO SUFICIENTE PARA QUE EL ANTIBIOTICO SOLUBILIZADO EN EL CALDO ALCALINO SEA ABSORBIDO POR EL ABSORBENTE REALIZADO POR AGITACION O MEZCLA; d)AJUSTAR EL pH DEL CALDO A CASI NEUTRAL ENTRE 6 Y 8 A FIN DE ESTABILIZAR EL ANTIBIOTICO ADSORBIDO EN EL ADSORBENTE; e)SEPARAR EL ADSORBENTE EN EL CUAL EL ANTIBIOTICO ES ADSORBIDO A PARTIR DEL CALDO, f)SEPARAR EL ANTIBIOTICO DEL ADSORBENTE POR ELUCION CON ACETATO DE ETILO; SIENDO EL ANTIBIOTICO OLIGOSACARIDO DE FORMULA I, DONDE X1 Y X2 SON H, Cl; UNO DE X1 Y X2 ES Cl; R ES NO2, NO, NHOH, NH2; R1 ES H, OH; R2 ES OH, OR12; R12 ES ALQUILO, COR13; R13 ES ALQUILO; R3 ES H, OH, CH(CH3)OCH3, COR14, ENTRE OTROS; R14 ES H, ALQUILO; R4 ES H, OH; R5 ES H, METILO; R20 Y R21 SON OH, OCH3; R22 ES H, CH3, CH3OH
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21568998A | 1998-12-18 | 1998-12-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20001370A1 true PE20001370A1 (es) | 2000-12-09 |
Family
ID=22803963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1999001277A PE20001370A1 (es) | 1998-12-18 | 1999-12-16 | Proceso para recuperar antibioticos oligosacaridos lipofilicos |
Country Status (5)
| Country | Link |
|---|---|
| AR (1) | AR021717A1 (es) |
| AU (1) | AU2157200A (es) |
| CO (1) | CO5231233A1 (es) |
| PE (1) | PE20001370A1 (es) |
| WO (1) | WO2000037670A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200812687A (en) * | 2006-07-10 | 2008-03-16 | Sicor Inc | Apparatus for the separation of a resin from a reaction mixture |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1173368B (it) * | 1984-02-24 | 1987-06-24 | Zambon Spa | Processo per la preparazione di acidi alfa-arilalcanoici otticamente attivi |
| US4735903A (en) * | 1984-06-21 | 1988-04-05 | Schering Corporation | Micromonospora carbonacea var africana |
| EP0610295A1 (en) * | 1991-10-16 | 1994-08-17 | Schering Corporation | Lipophilic oligosaccharide antibiotic salt compositions |
| US5763600A (en) * | 1997-04-18 | 1998-06-09 | Schering Corporation | Oligosaccharide antibiotics and process for preparation thereof |
-
1999
- 1999-12-16 PE PE1999001277A patent/PE20001370A1/es not_active Application Discontinuation
- 1999-12-16 CO CO99078839A patent/CO5231233A1/es not_active Application Discontinuation
- 1999-12-16 AU AU21572/00A patent/AU2157200A/en not_active Abandoned
- 1999-12-16 WO PCT/US1999/027937 patent/WO2000037670A1/en active Application Filing
- 1999-12-16 AR ARP990106460A patent/AR021717A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CO5231233A1 (es) | 2002-12-27 |
| WO2000037670A1 (en) | 2000-06-29 |
| AU2157200A (en) | 2000-07-12 |
| AR021717A1 (es) | 2002-07-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application declared void or lapsed |