PA8564301A1 - Comprimido de nelfinavir de dosis incrementada y metodo para fabricarlo - Google Patents
Comprimido de nelfinavir de dosis incrementada y metodo para fabricarloInfo
- Publication number
- PA8564301A1 PA8564301A1 PA20038564301A PA8564301A PA8564301A1 PA 8564301 A1 PA8564301 A1 PA 8564301A1 PA 20038564301 A PA20038564301 A PA 20038564301A PA 8564301 A PA8564301 A PA 8564301A PA 8564301 A1 PA8564301 A1 PA 8564301A1
- Authority
- PA
- Panama
- Prior art keywords
- nelfinavir
- compressed
- manufacture
- increased dose
- mixture
- Prior art date
Links
- QAGYKUNXZHXKMR-UHFFFAOYSA-N CPD000469186 Natural products CC1=C(O)C=CC=C1C(=O)NC(C(O)CN1C(CC2CCCCC2C1)C(=O)NC(C)(C)C)CSC1=CC=CC=C1 QAGYKUNXZHXKMR-UHFFFAOYSA-N 0.000 title abstract 5
- 229960000884 nelfinavir Drugs 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- QAGYKUNXZHXKMR-HKWSIXNMSA-N nelfinavir Chemical compound CC1=C(O)C=CC=C1C(=O)N[C@H]([C@H](O)CN1[C@@H](C[C@@H]2CCCC[C@@H]2C1)C(=O)NC(C)(C)C)CSC1=CC=CC=C1 QAGYKUNXZHXKMR-HKWSIXNMSA-N 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 238000005469 granulation Methods 0.000 abstract 2
- 230000003179 granulation Effects 0.000 abstract 2
- -1 NELFINAVIR COMPOUND Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Glanulating (AREA)
Abstract
UN COMPRIMIDO DE NELFINAVIR DE DOSIS ELEVADA QUE TIENE UNA RELACION EN PESO DE NELFINAVIR A AGLUTINANTE DE APROXIMADAMENTE 3:1 A APROXIMADAMENTE 5:1. LOS COMPRIMIDOS DE NELFINAVIR DE DOSIS ELEVADA SE FABRICAN EN UN PROCEDIMIENTO EN EL QUE SE FORMA UNA MEZCLA GRANULADA DE UN COMPUESTO DE NELFINAVIR Y UN AGLUTINANTE, EN UN PROCEDIMIENTO DE GRANULACION, Y A CONTINUACION SE ELABORA PARA FORMAR LOS COMPRIMIDOS. EN EL PROCEDIMIENTO DE GRANULACION SE ANADE HUMEDAD Y SE APLICA ENERGIA MECANICA A LA MEZCLA, Y LA MEZCLA SE CURA SIN ADICION DE HUMEDAD O APLICACION DE ENERGIA MECANICA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35142002P | 2002-01-28 | 2002-01-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PA8564301A1 true PA8564301A1 (es) | 2003-09-05 |
Family
ID=27663002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PA20038564301A PA8564301A1 (es) | 2002-01-28 | 2003-01-28 | Comprimido de nelfinavir de dosis incrementada y metodo para fabricarlo |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1469836A1 (es) |
| JP (1) | JP2005521661A (es) |
| KR (1) | KR20040079952A (es) |
| CN (1) | CN1713895A (es) |
| AR (1) | AR038236A1 (es) |
| BR (1) | BR0307190A (es) |
| CA (1) | CA2398226A1 (es) |
| GT (1) | GT200300016A (es) |
| HN (1) | HN2003000048A (es) |
| HU (1) | HUP0500512A2 (es) |
| IL (1) | IL162724A0 (es) |
| MX (1) | MXPA04007237A (es) |
| NI (1) | NI200300001A (es) |
| NO (1) | NO20043238L (es) |
| NZ (1) | NZ533283A (es) |
| PA (1) | PA8564301A1 (es) |
| PE (1) | PE20030730A1 (es) |
| PL (1) | PL373882A1 (es) |
| RU (1) | RU2004123206A (es) |
| SV (1) | SV2004001467A (es) |
| TW (1) | TW200302111A (es) |
| WO (1) | WO2003063837A1 (es) |
| ZA (1) | ZA200404367B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008053276A1 (en) * | 2006-10-30 | 2008-05-08 | Collette Nv | Transition piece for the transfer of powder or granular material from a discharge opening to a conveying line and method of transferring powder or granular material |
| KR20100057885A (ko) * | 2007-09-03 | 2010-06-01 | 알카텔-루센트 유에스에이 인코포레이티드 | Ｉｐ 네트워크 상의 ｉｐ 링크의 접속 상태를 자동으로 확인하는 방법 및 시스템 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6499984B1 (en) * | 2000-05-22 | 2002-12-31 | Warner-Lambert Company | Continuous production of pharmaceutical granulation |
| CZ20033211A3 (cs) * | 2001-05-03 | 2004-09-15 | F. Hoffmann-La Roche Ag | Farmaceutická léková forma amorfního nelfinavir mesylátu |
-
2002
- 2002-08-15 CA CA002398226A patent/CA2398226A1/en not_active Abandoned
-
2003
- 2003-01-07 NI NI200300001A patent/NI200300001A/es unknown
- 2003-01-16 BR BR0307190-1A patent/BR0307190A/pt not_active IP Right Cessation
- 2003-01-16 IL IL16272403A patent/IL162724A0/xx unknown
- 2003-01-16 PL PL03373882A patent/PL373882A1/xx not_active Application Discontinuation
- 2003-01-16 KR KR10-2004-7011562A patent/KR20040079952A/ko not_active Ceased
- 2003-01-16 NZ NZ533283A patent/NZ533283A/en unknown
- 2003-01-16 HU HU0500512A patent/HUP0500512A2/hu unknown
- 2003-01-16 JP JP2003563531A patent/JP2005521661A/ja active Pending
- 2003-01-16 EP EP03700070A patent/EP1469836A1/en not_active Withdrawn
- 2003-01-16 CN CNA038028360A patent/CN1713895A/zh active Pending
- 2003-01-16 MX MXPA04007237A patent/MXPA04007237A/es unknown
- 2003-01-16 RU RU2004123206/15A patent/RU2004123206A/ru not_active Application Discontinuation
- 2003-01-16 WO PCT/IB2003/000117 patent/WO2003063837A1/en not_active Ceased
- 2003-01-24 PE PE2003000074A patent/PE20030730A1/es not_active Application Discontinuation
- 2003-01-27 SV SV2003001467A patent/SV2004001467A/es not_active Application Discontinuation
- 2003-01-27 AR ARP030100228A patent/AR038236A1/es unknown
- 2003-01-27 HN HN2003000048A patent/HN2003000048A/es unknown
- 2003-01-27 TW TW092101739A patent/TW200302111A/zh unknown
- 2003-01-28 PA PA20038564301A patent/PA8564301A1/es unknown
- 2003-01-28 GT GT200300016A patent/GT200300016A/es unknown
-
2004
- 2004-06-03 ZA ZA200404367A patent/ZA200404367B/en unknown
- 2004-08-02 NO NO20043238A patent/NO20043238L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GT200300016A (es) | 2003-09-11 |
| KR20040079952A (ko) | 2004-09-16 |
| CN1713895A (zh) | 2005-12-28 |
| CA2398226A1 (en) | 2003-07-28 |
| SV2004001467A (es) | 2004-05-07 |
| HN2003000048A (es) | 2003-10-28 |
| WO2003063837A1 (en) | 2003-08-07 |
| TW200302111A (en) | 2003-08-01 |
| NI200300001A (es) | 2004-12-21 |
| NO20043238L (no) | 2004-08-02 |
| RU2004123206A (ru) | 2005-04-20 |
| MXPA04007237A (es) | 2004-10-29 |
| PE20030730A1 (es) | 2003-08-28 |
| JP2005521661A (ja) | 2005-07-21 |
| NZ533283A (en) | 2006-12-22 |
| IL162724A0 (en) | 2005-11-20 |
| ZA200404367B (en) | 2006-05-31 |
| BR0307190A (pt) | 2004-11-03 |
| EP1469836A1 (en) | 2004-10-27 |
| PL373882A1 (en) | 2005-09-19 |
| HUP0500512A2 (hu) | 2005-09-28 |
| AR038236A1 (es) | 2005-01-05 |
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