OA10707A - Terapeutic compounds. - Google Patents

Terapeutic compounds. Download PDF

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Publication number
OA10707A
OA10707A OA9800098A OA9800098A OA10707A OA 10707 A OA10707 A OA 10707A OA 9800098 A OA9800098 A OA 9800098A OA 9800098 A OA9800098 A OA 9800098A OA 10707 A OA10707 A OA 10707A
Authority
OA
OAPI
Prior art keywords
alkyl
mmol
benzimidazole
beta
formula
Prior art date
Application number
OA9800098A
Other languages
English (en)
Inventor
Stanley Chamberlain
George Walter Koszalka
Jeffrey H Tidwell
Nanine Van Draanen
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of OA10707A publication Critical patent/OA10707A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
OA9800098A 1996-01-05 1998-06-30 Terapeutic compounds. OA10707A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9600143.3A GB9600143D0 (en) 1996-01-05 1996-01-05 Therapeutic compounds

Publications (1)

Publication Number Publication Date
OA10707A true OA10707A (en) 2001-05-09

Family

ID=10786611

Family Applications (1)

Application Number Title Priority Date Filing Date
OA9800098A OA10707A (en) 1996-01-05 1998-06-30 Terapeutic compounds.

Country Status (21)

Country Link
US (2) US6204249B1 (hu)
EP (1) EP0876389A1 (hu)
JP (1) JP2000515119A (hu)
KR (1) KR19990077041A (hu)
CN (1) CN1214049A (hu)
AP (1) AP9801286A0 (hu)
AU (1) AU729541B2 (hu)
BR (1) BR9612413A (hu)
CA (1) CA2241993A1 (hu)
CZ (1) CZ212698A3 (hu)
EA (1) EA001770B1 (hu)
GB (1) GB9600143D0 (hu)
HU (1) HUP9904301A3 (hu)
IS (1) IS4789A (hu)
MX (1) MX9805441A (hu)
NO (1) NO983090L (hu)
NZ (1) NZ324380A (hu)
OA (1) OA10707A (hu)
PL (1) PL327732A1 (hu)
TR (1) TR199801289T2 (hu)
WO (1) WO1997025337A1 (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0845001B1 (en) * 1995-08-18 2002-11-13 The Regents of The University of Michigan 5'-substituted-ribofuranosyl benzimidazoles as antiviral agents
GB9600143D0 (en) * 1996-01-05 1996-03-06 Wellcome Found Therapeutic compounds
US6413938B1 (en) 1997-02-13 2002-07-02 The Regents Of The University Of Michigan Benzimidazole derivatives for the treatment of viral infections
CA2281927C (en) 1997-02-25 2004-01-27 Christopher J. Michejda Substituted benzimidazoles as non-nucleoside inhibitors of reverse transcriptase
US6455506B1 (en) 1997-07-30 2002-09-24 Smithkline Beecham Corporation Lyxofuranosyl benzimidazoles as antiviral agents
GB9807354D0 (en) 1998-04-07 1998-06-03 Glaxo Group Ltd Antiviral compound
GB9807355D0 (en) * 1998-04-07 1998-06-03 Glaxo Group Ltd Antiviral compound
GB0008939D0 (en) 2000-04-11 2000-05-31 Glaxo Group Ltd Process for preparing substituted benzimidazole compounds
EP1698635B1 (en) 2003-12-26 2011-12-14 Kissei Pharmaceutical Co., Ltd. Benzimidazole derivatives and medical uses thereof
CN101918422A (zh) 2007-10-05 2010-12-15 株式会社Api 呋喃核糖衍生物的制备方法
JP7376108B2 (ja) * 2020-06-23 2023-11-08 バイオメトリックス テクノロジーズ インコーポレイテッド 新規なベンズイミダゾール誘導体、その製造方法及びその抗癌剤または抗ウイルス剤としての用途
WO2024081308A1 (en) 2022-10-12 2024-04-18 Takeda Pharmaceutical Company Limited Method of preparing maribavir
WO2024103979A1 (zh) * 2022-11-17 2024-05-23 北京凯因科技股份有限公司 一种抑制疱疹病毒的化合物

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE130030C (hu)
US3399987A (en) 1965-08-02 1968-09-03 United States Borax Chem 2-alkylaminobenzimidazoles as herbicides
CH443777A (de) 1965-08-06 1968-02-15 Agripat Sa Verfahren zum Schützen textiler Keratinfasern vor Insektenfrass und Mittel zur Durchführung dieses Verfahrens
US3655901A (en) 1970-07-30 1972-04-11 Merck & Co Inc Method of inhibiting the formation of phenylethanalamine-n-methyl transferase with 2-aminobenzimidazoles
US4002623A (en) 1974-08-07 1977-01-11 Pfizer Inc. Anti-inflammatory 1-[3-(dialkylamino)propyl]-2-acylaminobenzimidazoles and 2-acylamino-3-[3-(dialkylamino)-propyl]imidazo[4,5-b]pyridines
FR2551442B1 (fr) 1983-09-05 1987-04-30 Centre Nat Rech Scient Nouveaux derives furaniques, leur preparation et leur application
EP0304624A3 (de) 1987-07-29 1989-03-22 F. Hoffmann-La Roche Ag Benzimidazol-2-yl-pyridiniumverbindungen
IT1226100B (it) 1988-07-07 1990-12-10 Dompe Farmaceutici Spa Derivati benzimidazolici farmacologicamente attivi.
SE9003151D0 (sv) 1990-10-02 1990-10-02 Medivir Ab Nucleoside derivatives
US5248672A (en) 1990-11-01 1993-09-28 The Regents Of The University Of Michigan Polysubstituted benzimidazole nucleosides as antiviral agents
WO1992018517A1 (en) 1991-04-17 1992-10-29 Yale University Method of treating or preventing hepatitis b virus
ZA923641B (en) 1991-05-21 1993-02-24 Iaf Biochem Int Processes for the diastereoselective synthesis of nucleosides
GB9205071D0 (en) 1992-03-09 1992-04-22 Wellcome Found Therapeutic nucleosides
AU5447094A (en) * 1992-10-21 1994-05-09 Regents Of The University Of Michigan, The Polysubstituted benzimidazoles as antiviral agents
GB9226879D0 (en) 1992-12-23 1993-02-17 Iaf Biochem Int Anti-viral compounds
US5399580A (en) 1993-03-08 1995-03-21 Burroughs Wellcome Co. Therapeutic nucleosides-uses
GB9413724D0 (en) * 1994-07-07 1994-08-24 Wellcome Found Therapeutic nucleosides
EP0845001B1 (en) 1995-08-18 2002-11-13 The Regents of The University of Michigan 5'-substituted-ribofuranosyl benzimidazoles as antiviral agents
GB9600143D0 (en) * 1996-01-05 1996-03-06 Wellcome Found Therapeutic compounds
US5995610A (en) * 1997-05-06 1999-11-30 Telefonaktiebolaget Lm Ericsson Cooperative call processing across public and private intelligent networks

Also Published As

Publication number Publication date
PL327732A1 (en) 1998-12-21
GB9600143D0 (en) 1996-03-06
EA001770B1 (ru) 2001-08-27
WO1997025337A1 (en) 1997-07-17
TR199801289T2 (en) 1998-10-21
HUP9904301A3 (en) 2001-07-30
CN1214049A (zh) 1999-04-14
NO983090D0 (no) 1998-07-03
EA199800526A1 (ru) 1999-04-29
EP0876389A1 (en) 1998-11-11
JP2000515119A (ja) 2000-11-14
AU729541B2 (en) 2001-02-01
CZ212698A3 (cs) 1998-12-16
HUP9904301A2 (hu) 2000-05-28
BR9612413A (pt) 1999-07-13
NZ324380A (en) 2000-01-28
NO983090L (no) 1998-09-01
US6204249B1 (en) 2001-03-20
MX9805441A (es) 1998-11-30
AU1164097A (en) 1997-08-01
AP9801286A0 (en) 1998-09-30
IS4789A (is) 1998-06-30
CA2241993A1 (en) 1997-07-17
KR19990077041A (ko) 1999-10-25
US6617315B1 (en) 2003-09-09

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