OA04406A - Procédé de préparation de dérivés de 14-hydroxy-morphinane. - Google Patents
Procédé de préparation de dérivés de 14-hydroxy-morphinane.Info
- Publication number
- OA04406A OA04406A OA54906A OA54906A OA04406A OA 04406 A OA04406 A OA 04406A OA 54906 A OA54906 A OA 54906A OA 54906 A OA54906 A OA 54906A OA 04406 A OA04406 A OA 04406A
- Authority
- OA
- OAPI
- Prior art keywords
- hydroxy
- preparation
- morphinan derivatives
- morphinan
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
- C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25187972A | 1972-05-10 | 1972-05-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA04406A true OA04406A (fr) | 1980-02-29 |
Family
ID=22953785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA54906A OA04406A (fr) | 1972-05-10 | 1973-05-09 | Procédé de préparation de dérivés de 14-hydroxy-morphinane. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3775414A (xx) |
| JP (1) | JPS535672B2 (xx) |
| CA (1) | CA989827A (xx) |
| CH (1) | CH590238A5 (xx) |
| CS (3) | CS178425B2 (xx) |
| DD (1) | DD106841A5 (xx) |
| DK (1) | DK138492B (xx) |
| HU (2) | HU168597B (xx) |
| IL (1) | IL42219A (xx) |
| NL (1) | NL155256B (xx) |
| OA (1) | OA04406A (xx) |
| SE (2) | SE403106B (xx) |
| YU (1) | YU36505B (xx) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3910920A (en) * | 1973-11-07 | 1975-10-07 | Bristol Myers Co | 3,14,17-Substituted-6,7-tetramethylenemorphinans |
| US3980641A (en) * | 1975-07-31 | 1976-09-14 | Bristol-Myers Company | Process for the preparation of 14-hydroxymorphinans |
| US4017497A (en) * | 1975-11-18 | 1977-04-12 | Bristol-Myers Company | Process for the preparation of 14-hydroxymorphinan derivatives |
| US4139534A (en) * | 1977-02-17 | 1979-02-13 | Bristol-Myers Company | Process for the preparation of 14-hydroxymorphinan derivatives |
| JPS52136176A (en) * | 1976-03-23 | 1977-11-14 | Bristol Myers Co | Method of improving 144hydroxymorphinan derivatives |
| US4052389A (en) * | 1976-03-23 | 1977-10-04 | Bristol-Myers Company | Derivatives of 9,10-dihydroxy-1-(p-alkoxybenzyl)-perhydroisoquinoline oxazine-3-one |
| US4115389A (en) * | 1977-05-02 | 1978-09-19 | Bristol-Myers Company | Process of N-demethylating (-)-1-(p-methoxybenzyl)-2-methyl-1,2,3,4,5,6,7,8-octahydroisoquinoline |
| NO793297L (no) * | 1978-10-19 | 1980-04-22 | Mallinckrodt Inc | Fremgangsmaate til fremstilling av oksymorfon |
| US4272540A (en) * | 1979-04-24 | 1981-06-09 | Sisa, Incorporated | 14-Methoxymorphinan-6-one compounds and therapeutic methods of treating pain and drug dependence with them |
| NO802139L (no) * | 1979-08-09 | 1981-02-10 | Mallinckrodt Inc | Utgangsforbindelser for fremstilling av morfinderivater, samt fremgangsmaate til fremstilling av utgangsforbindelsene |
| US5109136A (en) * | 1990-08-09 | 1992-04-28 | Warner-Lambert Company | Tetracyclic amines useful as cerebrovascular agents |
| ES2750853T3 (es) | 2014-10-14 | 2020-03-27 | Hisamitsu Pharmaceutical Co | Parche adhesivo |
| MX2018011877A (es) * | 2016-03-29 | 2019-03-06 | Hikal Ltd | Proceso mejorado para la preparacion de tartrato de butorfanol. |
| WO2018123822A1 (ja) | 2016-12-28 | 2018-07-05 | 久光製薬株式会社 | ブトルファノール含有貼付剤 |
| EP3616698B1 (en) | 2017-04-25 | 2021-01-27 | Hisamitsu Pharmaceutical Co., Inc. | Adhesive patch |
| WO2018198925A1 (ja) | 2017-04-25 | 2018-11-01 | 久光製薬株式会社 | 貼付剤 |
| CN112592342B (zh) * | 2021-01-15 | 2022-02-22 | 福安药业集团重庆礼邦药物开发有限公司 | 一种布托啡诺脱环丁基杂质化合物的制备方法 |
-
1972
- 1972-05-10 US US00251879A patent/US3775414A/en not_active Expired - Lifetime
-
1973
- 1973-05-01 CA CA170,185A patent/CA989827A/en not_active Expired
- 1973-05-07 YU YU01197/73A patent/YU36505B/xx unknown
- 1973-05-07 NL NL737306344A patent/NL155256B/xx unknown
- 1973-05-08 SE SE7306479A patent/SE403106B/xx unknown
- 1973-05-08 DD DD170682A patent/DD106841A5/xx unknown
- 1973-05-08 CH CH652673A patent/CH590238A5/xx not_active IP Right Cessation
- 1973-05-08 IL IL42219A patent/IL42219A/en unknown
- 1973-05-09 JP JP5080073A patent/JPS535672B2/ja not_active Expired
- 1973-05-09 OA OA54906A patent/OA04406A/xx unknown
- 1973-05-10 HU HUBI470A patent/HU168597B/hu unknown
- 1973-05-10 CS CS3317A patent/CS178425B2/cs unknown
- 1973-05-10 CS CS7423A patent/CS178446B2/cs unknown
- 1973-05-10 CS CS7424A patent/CS178447B2/cs unknown
- 1973-05-10 DK DK259373AA patent/DK138492B/da unknown
- 1973-05-10 HU HUBI513A patent/HU169023B/hu unknown
-
1976
- 1976-04-08 SE SE7604162A patent/SE411042B/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK138492C (xx) | 1979-02-19 |
| CA989827A (en) | 1976-05-25 |
| SE7604162L (sv) | 1976-04-08 |
| DD106841A5 (xx) | 1974-07-05 |
| NL155256B (nl) | 1977-12-15 |
| JPS4961169A (xx) | 1974-06-13 |
| JPS535672B2 (xx) | 1978-03-01 |
| SE411042B (sv) | 1979-11-26 |
| IL42219A0 (en) | 1973-07-30 |
| YU36505B (en) | 1984-02-29 |
| CS178447B2 (xx) | 1977-09-15 |
| CH590238A5 (xx) | 1977-07-29 |
| CS178425B2 (xx) | 1977-09-15 |
| NL7306344A (xx) | 1973-11-13 |
| YU119773A (en) | 1982-02-25 |
| SE403106B (sv) | 1978-07-31 |
| HU169023B (xx) | 1976-09-28 |
| IL42219A (en) | 1977-06-30 |
| US3775414A (en) | 1973-11-27 |
| DK138492B (da) | 1978-09-18 |
| CS178446B2 (xx) | 1977-09-15 |
| HU168597B (xx) | 1976-06-28 |
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