NZ771810B2 - An agrochemical composition - Google Patents
An agrochemical composition Download PDFInfo
- Publication number
- NZ771810B2 NZ771810B2 NZ771810A NZ77181019A NZ771810B2 NZ 771810 B2 NZ771810 B2 NZ 771810B2 NZ 771810 A NZ771810 A NZ 771810A NZ 77181019 A NZ77181019 A NZ 77181019A NZ 771810 B2 NZ771810 B2 NZ 771810B2
- Authority
- NZ
- New Zealand
- Prior art keywords
- composition
- agrochemical composition
- agrochemical
- zinc
- present
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 460
- 239000003905 agrochemical Substances 0.000 title claims abstract description 181
- -1 suspoemulsions Substances 0.000 claims abstract description 120
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 76
- RRAFCDWBNXTKKO-UHFFFAOYSA-N Eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 claims abstract description 72
- 239000011780 sodium chloride Substances 0.000 claims abstract description 70
- 150000003839 salts Chemical class 0.000 claims abstract description 66
- 239000008187 granular material Substances 0.000 claims abstract description 55
- 239000005770 Eugenol Substances 0.000 claims abstract description 36
- 229960002217 Eugenol Drugs 0.000 claims abstract description 36
- 239000002245 particle Substances 0.000 claims abstract description 26
- HCHKCACWOHOZIP-UHFFFAOYSA-N zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 24
- 239000011701 zinc Substances 0.000 claims abstract description 24
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 24
- 239000004562 water dispersible granule Substances 0.000 claims abstract description 23
- 239000004546 suspension concentrate Substances 0.000 claims abstract description 22
- 239000000839 emulsion Substances 0.000 claims abstract description 21
- 239000006194 liquid suspension Substances 0.000 claims abstract description 19
- 239000002689 soil Substances 0.000 claims abstract description 14
- 239000007900 aqueous suspension Substances 0.000 claims abstract description 13
- 239000000463 material Substances 0.000 claims abstract description 12
- 239000004495 emulsifiable concentrate Substances 0.000 claims abstract description 10
- 239000003795 chemical substances by application Substances 0.000 claims description 63
- 241000196324 Embryophyta Species 0.000 claims description 48
- 239000007788 liquid Substances 0.000 claims description 31
- 239000003337 fertilizer Substances 0.000 claims description 26
- 229940091251 Zinc Supplements Drugs 0.000 claims description 23
- 239000000725 suspension Substances 0.000 claims description 22
- XLOMVQKBTHCTTD-UHFFFAOYSA-N zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims description 22
- 239000007787 solid Substances 0.000 claims description 19
- 239000000969 carrier Substances 0.000 claims description 18
- UIIMBOGNXHQVGW-UHFFFAOYSA-M buffer Substances [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 16
- 235000015097 nutrients Nutrition 0.000 claims description 14
- 150000003751 zinc Chemical class 0.000 claims description 14
- 239000003906 humectant Substances 0.000 claims description 13
- 239000004533 oil dispersion Substances 0.000 claims description 13
- 239000002904 solvent Substances 0.000 claims description 13
- 239000004094 surface-active agent Substances 0.000 claims description 13
- 239000004548 suspo-emulsion Substances 0.000 claims description 12
- 239000011787 zinc oxide Substances 0.000 claims description 11
- 239000011230 binding agent Substances 0.000 claims description 10
- 230000012010 growth Effects 0.000 claims description 10
- 239000002518 antifoaming agent Substances 0.000 claims description 9
- 239000000575 pesticide Substances 0.000 claims description 9
- 230000002335 preservative Effects 0.000 claims description 9
- 239000003755 preservative agent Substances 0.000 claims description 9
- 239000003899 bactericide agent Substances 0.000 claims description 8
- 230000000361 pesticidal Effects 0.000 claims description 8
- 238000003892 spreading Methods 0.000 claims description 8
- 239000004563 wettable powder Substances 0.000 claims description 8
- 239000005648 plant growth regulator Substances 0.000 claims description 7
- 239000003381 stabilizer Substances 0.000 claims description 7
- 241000195493 Cryptophyta Species 0.000 claims description 6
- 244000052616 bacterial pathogens Species 0.000 claims description 6
- 230000002708 enhancing Effects 0.000 claims description 6
- 230000003472 neutralizing Effects 0.000 claims description 6
- 239000000419 plant extract Substances 0.000 claims description 6
- 239000000341 volatile oil Substances 0.000 claims description 6
- 230000000844 anti-bacterial Effects 0.000 claims description 5
- 238000007710 freezing Methods 0.000 claims description 5
- ONDPHDOFVYQSGI-UHFFFAOYSA-N Zinc nitrate Chemical compound [Zn+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O ONDPHDOFVYQSGI-UHFFFAOYSA-N 0.000 claims description 4
- 239000002250 absorbent Substances 0.000 claims description 4
- 230000002745 absorbent Effects 0.000 claims description 4
- LILHXQCLSOZSRO-UHFFFAOYSA-J dizinc;oxozinc;dicarbonate;tetrahydrate Chemical compound O.O.O.O.[Zn+2].[Zn+2].[Zn]=O.[Zn]=O.[Zn]=O.[O-]C([O-])=O.[O-]C([O-])=O LILHXQCLSOZSRO-UHFFFAOYSA-J 0.000 claims description 4
- 239000003995 emulsifying agent Substances 0.000 claims description 4
- 239000006254 rheological additive Substances 0.000 claims description 4
- 239000004034 viscosity adjusting agent Substances 0.000 claims description 4
- 239000011667 zinc carbonate Substances 0.000 claims description 4
- 235000004416 zinc carbonate Nutrition 0.000 claims description 4
- 229910000010 zinc carbonate Inorganic materials 0.000 claims description 4
- 235000016639 Syzygium aromaticum Nutrition 0.000 claims description 3
- 240000005147 Syzygium aromaticum Species 0.000 claims description 3
- DJWUNCQRNNEAKC-UHFFFAOYSA-L Zinc acetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O DJWUNCQRNNEAKC-UHFFFAOYSA-L 0.000 claims description 3
- 239000003085 diluting agent Substances 0.000 claims description 3
- 239000002270 dispersing agent Substances 0.000 claims description 3
- 239000000945 filler Substances 0.000 claims description 3
- 230000000855 fungicidal Effects 0.000 claims description 3
- 239000000417 fungicide Substances 0.000 claims description 3
- KREXGRSOTUKPLX-UHFFFAOYSA-N octadecanoic acid;zinc Chemical compound [Zn].CCCCCCCCCCCCCCCCCC(O)=O.CCCCCCCCCCCCCCCCCC(O)=O KREXGRSOTUKPLX-UHFFFAOYSA-N 0.000 claims description 3
- 239000003352 sequestering agent Substances 0.000 claims description 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 3
- 239000011593 sulfur Substances 0.000 claims description 3
- 229910052717 sulfur Inorganic materials 0.000 claims description 3
- 239000002562 thickening agent Substances 0.000 claims description 3
- 239000000080 wetting agent Substances 0.000 claims description 3
- 239000004246 zinc acetate Substances 0.000 claims description 3
- 240000000662 Anethum graveolens Species 0.000 claims description 2
- 240000007087 Apium graveolens Species 0.000 claims description 2
- 235000015849 Apium graveolens Dulce Group Nutrition 0.000 claims description 2
- 235000010591 Appio Nutrition 0.000 claims description 2
- 235000003097 Artemisia absinthium Nutrition 0.000 claims description 2
- 240000001851 Artemisia dracunculus Species 0.000 claims description 2
- 235000003261 Artemisia vulgaris Nutrition 0.000 claims description 2
- 241000723347 Cinnamomum Species 0.000 claims description 2
- 244000223760 Cinnamomum zeylanicum Species 0.000 claims description 2
- 235000004310 Cinnamomum zeylanicum Nutrition 0.000 claims description 2
- 235000010654 Melissa officinalis Nutrition 0.000 claims description 2
- 240000004119 Melissa officinalis Species 0.000 claims description 2
- 235000009421 Myristica fragrans Nutrition 0.000 claims description 2
- 240000006984 Myristica fragrans Species 0.000 claims description 2
- 235000010676 Ocimum basilicum Nutrition 0.000 claims description 2
- 240000003982 Ocimum basilicum Species 0.000 claims description 2
- HVTHJRMZXBWFNE-UHFFFAOYSA-J Sodium zincate Chemical compound [OH-].[OH-].[OH-].[OH-].[Na+].[Na+].[Zn+2] HVTHJRMZXBWFNE-UHFFFAOYSA-J 0.000 claims description 2
- 235000009499 Vanilla fragrans Nutrition 0.000 claims description 2
- 235000012036 Vanilla tahitensis Nutrition 0.000 claims description 2
- VNDYJBBGRKZCSX-UHFFFAOYSA-L Zinc bromide Chemical compound Br[Zn]Br VNDYJBBGRKZCSX-UHFFFAOYSA-L 0.000 claims description 2
- JIAARYAFYJHUJI-UHFFFAOYSA-L Zinc chloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 claims description 2
- UGZADUVQMDAIAO-UHFFFAOYSA-L Zinc hydroxide Chemical class [OH-].[OH-].[Zn+2] UGZADUVQMDAIAO-UHFFFAOYSA-L 0.000 claims description 2
- UAYWVJHJZHQCIE-UHFFFAOYSA-L Zinc iodide Chemical compound I[Zn]I UAYWVJHJZHQCIE-UHFFFAOYSA-L 0.000 claims description 2
- NWONKYPBYAMBJT-UHFFFAOYSA-L Zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 claims description 2
- 235000006886 Zingiber officinale Nutrition 0.000 claims description 2
- 240000007329 Zingiber officinale Species 0.000 claims description 2
- 239000001264 anethum graveolens Substances 0.000 claims description 2
- 239000001138 artemisia absinthium Substances 0.000 claims description 2
- 235000017803 cinnamon Nutrition 0.000 claims description 2
- 239000003086 colorant Substances 0.000 claims description 2
- 235000008397 ginger Nutrition 0.000 claims description 2
- 230000003050 macronutrient Effects 0.000 claims description 2
- 235000021073 macronutrients Nutrition 0.000 claims description 2
- 239000011785 micronutrient Substances 0.000 claims description 2
- 235000013369 micronutrients Nutrition 0.000 claims description 2
- 239000001702 nutmeg Substances 0.000 claims description 2
- ABLZXFCXXLZCGV-UHFFFAOYSA-N phosphorous acid Chemical compound OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 claims description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 2
- 239000011591 potassium Substances 0.000 claims description 2
- 229910052700 potassium Inorganic materials 0.000 claims description 2
- 235000013619 trace mineral Nutrition 0.000 claims description 2
- 235000009051 wormwood Nutrition 0.000 claims description 2
- 235000017731 wormwood Nutrition 0.000 claims description 2
- 229940102001 zinc bromide Drugs 0.000 claims description 2
- 239000011592 zinc chloride Substances 0.000 claims description 2
- 235000005074 zinc chloride Nutrition 0.000 claims description 2
- 229960001763 zinc sulfate Drugs 0.000 claims description 2
- 229910000368 zinc sulfate Inorganic materials 0.000 claims description 2
- 240000007232 Illicium verum Species 0.000 claims 1
- 235000008227 Illicium verum Nutrition 0.000 claims 1
- 244000290333 Vanilla fragrans Species 0.000 claims 1
- 239000008139 complexing agent Substances 0.000 claims 1
- 239000000618 nitrogen fertilizer Substances 0.000 claims 1
- 239000008247 solid mixture Substances 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 35
- 239000000843 powder Substances 0.000 abstract description 13
- 239000006185 dispersion Substances 0.000 abstract description 9
- 235000002639 sodium chloride Nutrition 0.000 description 67
- RTZKZFJDLAIYFH-UHFFFAOYSA-N diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 26
- 235000019441 ethanol Nutrition 0.000 description 25
- 201000010099 disease Diseases 0.000 description 24
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 21
- 239000002253 acid Substances 0.000 description 20
- 235000014113 dietary fatty acids Nutrition 0.000 description 20
- 239000000194 fatty acid Substances 0.000 description 20
- LYCAIKOWRPUZTN-UHFFFAOYSA-N glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 20
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 17
- 239000003921 oil Substances 0.000 description 17
- 235000019198 oils Nutrition 0.000 description 17
- 150000002148 esters Chemical class 0.000 description 16
- 239000004480 active ingredient Substances 0.000 description 14
- 125000000217 alkyl group Chemical group 0.000 description 14
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 14
- DNIAPMSPPWPWGF-UHFFFAOYSA-N propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 14
- 229920002472 Starch Polymers 0.000 description 13
- 235000019698 starch Nutrition 0.000 description 13
- 150000001298 alcohols Chemical class 0.000 description 12
- 150000001412 amines Chemical class 0.000 description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 12
- 235000013399 edible fruits Nutrition 0.000 description 11
- 239000011734 sodium Substances 0.000 description 11
- 229910052708 sodium Inorganic materials 0.000 description 11
- 238000003860 storage Methods 0.000 description 11
- 229940083542 Sodium Drugs 0.000 description 10
- 239000003963 antioxidant agent Substances 0.000 description 10
- 235000006708 antioxidants Nutrition 0.000 description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 10
- 235000015424 sodium Nutrition 0.000 description 10
- MTHSVFCYNBDYFN-UHFFFAOYSA-N Diethylene glycol Chemical class OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 9
- 150000004665 fatty acids Chemical class 0.000 description 9
- 235000021317 phosphate Nutrition 0.000 description 9
- KEAYESYHFKHZAL-UHFFFAOYSA-N sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 description 9
- 239000007921 spray Substances 0.000 description 9
- 235000015112 vegetable and seed oil Nutrition 0.000 description 9
- 235000010980 cellulose Nutrition 0.000 description 8
- 229920002678 cellulose Polymers 0.000 description 8
- 229920001577 copolymer Polymers 0.000 description 8
- 230000014759 maintenance of location Effects 0.000 description 8
- 239000008158 vegetable oil Substances 0.000 description 8
- 229960004063 Propylene glycol Drugs 0.000 description 7
- 241000607479 Yersinia pestis Species 0.000 description 7
- 239000001913 cellulose Substances 0.000 description 7
- WSFSSNUMVMOOMR-UHFFFAOYSA-N formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 7
- 235000013772 propylene glycol Nutrition 0.000 description 7
- 239000008107 starch Substances 0.000 description 7
- VZCYOOQTPOCHFL-OWOJBTEDSA-N (E)-but-2-enedioate;hydron Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 6
- PZZYQPZGQPZBDN-UHFFFAOYSA-N Aluminium silicate Chemical compound O=[Al]O[Si](=O)O[Al]=O PZZYQPZGQPZBDN-UHFFFAOYSA-N 0.000 description 6
- 241000233866 Fungi Species 0.000 description 6
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 6
- 150000007513 acids Chemical class 0.000 description 6
- 239000003139 biocide Substances 0.000 description 6
- 238000009826 distribution Methods 0.000 description 6
- 238000009472 formulation Methods 0.000 description 6
- 230000001965 increased Effects 0.000 description 6
- 230000001717 pathogenic Effects 0.000 description 6
- 229920001223 polyethylene glycol Polymers 0.000 description 6
- 229920000151 polyglycol Polymers 0.000 description 6
- 239000010695 polyglycol Substances 0.000 description 6
- XSQUKJJJFZCRTK-UHFFFAOYSA-N urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 6
- 239000005995 Aluminium silicate Substances 0.000 description 5
- 229920001451 Polypropylene glycol Polymers 0.000 description 5
- JNYAEWCLZODPBN-CTQIIAAMSA-N Sorbitan Chemical compound OCC(O)C1OCC(O)[C@@H]1O JNYAEWCLZODPBN-CTQIIAAMSA-N 0.000 description 5
- KWIUHFFTVRNATP-UHFFFAOYSA-N Trimethylglycine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 5
- 150000005215 alkyl ethers Chemical class 0.000 description 5
- 235000012211 aluminium silicate Nutrition 0.000 description 5
- 230000000111 anti-oxidant Effects 0.000 description 5
- 239000003429 antifungal agent Substances 0.000 description 5
- 239000004599 antimicrobial Substances 0.000 description 5
- 230000003078 antioxidant Effects 0.000 description 5
- 150000004945 aromatic hydrocarbons Chemical class 0.000 description 5
- 125000003118 aryl group Chemical group 0.000 description 5
- 239000000499 gel Substances 0.000 description 5
- 150000004676 glycans Polymers 0.000 description 5
- 238000003973 irrigation Methods 0.000 description 5
- 230000002262 irrigation Effects 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- PSZYNBSKGUBXEH-UHFFFAOYSA-M naphthalene-1-sulfonate Chemical class C1=CC=C2C(S(=O)(=O)[O-])=CC=CC2=C1 PSZYNBSKGUBXEH-UHFFFAOYSA-M 0.000 description 5
- 239000003208 petroleum Substances 0.000 description 5
- 239000010452 phosphate Substances 0.000 description 5
- 229920000058 polyacrylate Polymers 0.000 description 5
- 229920000570 polyether Polymers 0.000 description 5
- 229920000642 polymer Polymers 0.000 description 5
- 229920001282 polysaccharide Polymers 0.000 description 5
- 239000005017 polysaccharide Substances 0.000 description 5
- 150000004804 polysaccharides Polymers 0.000 description 5
- 239000000377 silicon dioxide Substances 0.000 description 5
- 238000003756 stirring Methods 0.000 description 5
- 235000019801 trisodium phosphate Nutrition 0.000 description 5
- 235000005979 Citrus limon Nutrition 0.000 description 4
- 240000002268 Citrus limon Species 0.000 description 4
- 229920001353 Dextrin Polymers 0.000 description 4
- 239000004375 Dextrin Substances 0.000 description 4
- KWGKDLIKAYFUFQ-UHFFFAOYSA-M Lithium chloride Chemical compound [Li+].[Cl-] KWGKDLIKAYFUFQ-UHFFFAOYSA-M 0.000 description 4
- 239000004698 Polyethylene (PE) Substances 0.000 description 4
- 239000002202 Polyethylene glycol Substances 0.000 description 4
- FGIUAXJPYTZDNR-UHFFFAOYSA-N Potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 description 4
- YGSDEFSMJLZEOE-UHFFFAOYSA-N Salicylic acid Chemical class OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 4
- VWDWKYIASSYTQR-UHFFFAOYSA-N Sodium nitrate Chemical compound [Na+].[O-][N+]([O-])=O VWDWKYIASSYTQR-UHFFFAOYSA-N 0.000 description 4
- LSNNMFCWUKXFEE-UHFFFAOYSA-L Sulphite Chemical compound [O-]S([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-L 0.000 description 4
- 229940046282 Zinc Drugs 0.000 description 4
- NBIIXXVUZAFLBC-UHFFFAOYSA-K [O-]P([O-])([O-])=O Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 4
- 230000036579 abiotic stress Effects 0.000 description 4
- 229910052783 alkali metal Inorganic materials 0.000 description 4
- 230000004790 biotic stress Effects 0.000 description 4
- 229920001400 block copolymer Polymers 0.000 description 4
- 239000004359 castor oil Substances 0.000 description 4
- 235000019438 castor oil Nutrition 0.000 description 4
- 235000019425 dextrin Nutrition 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- VZCYOOQTPOCHFL-UHFFFAOYSA-N fumaric acid Chemical compound OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 4
- 239000001530 fumaric acid Substances 0.000 description 4
- 235000011187 glycerol Nutrition 0.000 description 4
- 239000007952 growth promoter Substances 0.000 description 4
- 238000000265 homogenisation Methods 0.000 description 4
- 229910052500 inorganic mineral Inorganic materials 0.000 description 4
- 235000010755 mineral Nutrition 0.000 description 4
- 239000011707 mineral Substances 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 244000052769 pathogens Species 0.000 description 4
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 4
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 4
- KWYUFKZDYYNOTN-UHFFFAOYSA-M potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 239000002002 slurry Substances 0.000 description 4
- 235000017557 sodium bicarbonate Nutrition 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 239000001488 sodium phosphate Substances 0.000 description 4
- 159000000000 sodium salts Chemical class 0.000 description 4
- QAOWNCQODCNURD-UHFFFAOYSA-L sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 4
- 239000006273 synthetic pesticide Substances 0.000 description 4
- 239000003760 tallow Substances 0.000 description 4
- LNAZSHAWQACDHT-XIYTZBAFSA-N (2R,3R,4S,5R,6S)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2S,3R,4S,5R,6R)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2R,3R,4S,5R,6R)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical compound CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 description 3
- 244000215068 Acacia senegal Species 0.000 description 3
- 229960000686 Benzalkonium Chloride Drugs 0.000 description 3
- DMSMPAJRVJJAGA-UHFFFAOYSA-N Benzisothiazolinone Chemical compound C1=CC=C2C(=O)NSC2=C1 DMSMPAJRVJJAGA-UHFFFAOYSA-N 0.000 description 3
- WPYMKLBDIGXBTP-UHFFFAOYSA-N Benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 3
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 3
- 229960001927 Cetylpyridinium Chloride Drugs 0.000 description 3
- YMKDRGPMQRFJGP-UHFFFAOYSA-M Cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 description 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 3
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 3
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 description 3
- 229940113120 Dipropylene Glycol Drugs 0.000 description 3
- SZXQTJUDPRGNJN-UHFFFAOYSA-N Dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 3
- 108010010803 Gelatin Proteins 0.000 description 3
- 229920000084 Gum arabic Polymers 0.000 description 3
- BJEPYKJPYRNKOW-UHFFFAOYSA-N Malic acid Chemical compound OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 3
- LXCFILQKKLGQFO-UHFFFAOYSA-N Methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 3
- 239000004721 Polyphenylene oxide Substances 0.000 description 3
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 3
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 3
- 241000068898 Xanthomonas citri pv. citri Species 0.000 description 3
- 235000010489 acacia gum Nutrition 0.000 description 3
- 239000000205 acacia gum Substances 0.000 description 3
- PNEYBMLMFCGWSK-UHFFFAOYSA-N al2o3 Chemical compound [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 3
- 235000010443 alginic acid Nutrition 0.000 description 3
- 229920000615 alginic acid Polymers 0.000 description 3
- 150000001340 alkali metals Chemical class 0.000 description 3
- 150000001408 amides Chemical class 0.000 description 3
- 239000010775 animal oil Substances 0.000 description 3
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 3
- 239000004202 carbamide Substances 0.000 description 3
- 150000001720 carbohydrates Chemical class 0.000 description 3
- 235000014633 carbohydrates Nutrition 0.000 description 3
- 239000001768 carboxy methyl cellulose Substances 0.000 description 3
- 235000015165 citric acid Nutrition 0.000 description 3
- 229960004106 citric acid Drugs 0.000 description 3
- 239000004927 clay Substances 0.000 description 3
- 229910052570 clay Inorganic materials 0.000 description 3
- 239000010634 clove oil Substances 0.000 description 3
- 230000000536 complexating Effects 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 235000012343 cottonseed oil Nutrition 0.000 description 3
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 3
- 150000002170 ethers Chemical class 0.000 description 3
- 125000004494 ethyl ester group Chemical group 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 235000013312 flour Nutrition 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- BDAGIHXWWSANSR-UHFFFAOYSA-N formic acid Chemical compound OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 3
- 235000011087 fumaric acid Nutrition 0.000 description 3
- 229910021485 fumed silica Inorganic materials 0.000 description 3
- 239000008273 gelatin Substances 0.000 description 3
- 229920000159 gelatin Polymers 0.000 description 3
- 235000019322 gelatine Nutrition 0.000 description 3
- 235000011852 gelatine desserts Nutrition 0.000 description 3
- 239000004021 humic acid Substances 0.000 description 3
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 3
- 235000014655 lactic acid Nutrition 0.000 description 3
- 239000004310 lactic acid Substances 0.000 description 3
- 239000011976 maleic acid Substances 0.000 description 3
- 239000001630 malic acid Substances 0.000 description 3
- 229920000609 methyl cellulose Polymers 0.000 description 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 3
- 235000010981 methylcellulose Nutrition 0.000 description 3
- 239000001923 methylcellulose Substances 0.000 description 3
- PMZURENOXWZQFD-UHFFFAOYSA-L na2so4 Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 150000007524 organic acids Chemical class 0.000 description 3
- 235000005985 organic acids Nutrition 0.000 description 3
- MUBZPKHOEPUJKR-UHFFFAOYSA-N oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 description 3
- IAYPIBMASNFSPL-UHFFFAOYSA-N oxane Chemical class C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 3
- 239000003002 pH adjusting agent Substances 0.000 description 3
- HWGNBUXHKFFFIH-UHFFFAOYSA-I pentasodium;[oxido(phosphonatooxy)phosphoryl] phosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O HWGNBUXHKFFFIH-UHFFFAOYSA-I 0.000 description 3
- 150000003904 phospholipids Chemical class 0.000 description 3
- 229920001983 poloxamer Polymers 0.000 description 3
- 229920001888 polyacrylic acid Polymers 0.000 description 3
- 229920000573 polyethylene Polymers 0.000 description 3
- 229920005862 polyol Polymers 0.000 description 3
- 229920000136 polysorbate Polymers 0.000 description 3
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 3
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 3
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Substances [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- XBDQKXXYIPTUBI-UHFFFAOYSA-N propionic acid Chemical compound CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 3
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 3
- 238000003044 randomized block design Methods 0.000 description 3
- 239000000344 soap Substances 0.000 description 3
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 235000019832 sodium triphosphate Nutrition 0.000 description 3
- 239000000600 sorbitol Substances 0.000 description 3
- 239000000021 stimulant Substances 0.000 description 3
- 238000009736 wetting Methods 0.000 description 3
- KANAPVJGZDNSCZ-UHFFFAOYSA-N 1,2-benzothiazole 1-oxide Chemical class C1=CC=C2S(=O)N=CC2=C1 KANAPVJGZDNSCZ-UHFFFAOYSA-N 0.000 description 2
- YPFDHNVEDLHUCE-UHFFFAOYSA-N 1,3-Propanediol Chemical compound OCCCO YPFDHNVEDLHUCE-UHFFFAOYSA-N 0.000 description 2
- WERYXYBDKMZEQL-UHFFFAOYSA-N 1,4-Butanediol Chemical compound OCCCCO WERYXYBDKMZEQL-UHFFFAOYSA-N 0.000 description 2
- FCKYPQBAHLOOJQ-UHFFFAOYSA-N 2-[[2-[bis(carboxymethyl)amino]cyclohexyl]-(carboxymethyl)amino]acetic acid Chemical compound OC(=O)CN(CC(O)=O)C1CCCCC1N(CC(O)=O)CC(O)=O FCKYPQBAHLOOJQ-UHFFFAOYSA-N 0.000 description 2
- SAXQBSJDTDGBHS-UHFFFAOYSA-N 2-azaniumylethylazanium;diacetate Chemical compound CC([O-])=O.CC([O-])=O.[NH3+]CC[NH3+] SAXQBSJDTDGBHS-UHFFFAOYSA-N 0.000 description 2
- JVKUCNQGESRUCL-UHFFFAOYSA-N 2-hydroxyethyl 12-hydroxyoctadecanoate Chemical compound CCCCCCC(O)CCCCCCCCCCC(=O)OCCO JVKUCNQGESRUCL-UHFFFAOYSA-N 0.000 description 2
- ULUAUXLGCMPNKK-UHFFFAOYSA-L 2-sulfobutanedioate Chemical class OS(=O)(=O)C(C([O-])=O)CC([O-])=O ULUAUXLGCMPNKK-UHFFFAOYSA-L 0.000 description 2
- FCYKAQOGGFGCMD-UHFFFAOYSA-N 3,7,8-trihydroxy-3-methyl-10-oxo-1,4-dihydropyrano[4,3-b]chromene-9-carboxylic acid Chemical compound O1C2=CC(O)=C(O)C(C(O)=O)=C2C(=O)C2=C1CC(C)(O)OC2 FCYKAQOGGFGCMD-UHFFFAOYSA-N 0.000 description 2
- GHNRTXCRBJQVGN-UHFFFAOYSA-N 4-dodecan-6-ylbenzenesulfonic acid Chemical compound CCCCCCC(CCCCC)C1=CC=C(S(O)(=O)=O)C=C1 GHNRTXCRBJQVGN-UHFFFAOYSA-N 0.000 description 2
- BJRNKVDFDLYUGJ-RMPHRYRLSA-N ARBUTIN Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=C(O)C=C1 BJRNKVDFDLYUGJ-RMPHRYRLSA-N 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 2
- XJKJWTWGDGIQRH-BFIDDRIFSA-N Alginic acid Chemical compound O1[C@@H](C(O)=O)[C@@H](OC)[C@H](O)[C@H](O)[C@@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](C)[C@@H](O)[C@H]1O XJKJWTWGDGIQRH-BFIDDRIFSA-N 0.000 description 2
- 229940061720 Alpha Hydroxy Acids Drugs 0.000 description 2
- 241000416162 Astragalus gummifer Species 0.000 description 2
- UREZNYTWGJKWBI-UHFFFAOYSA-M Benzethonium chloride Chemical compound [Cl-].C1=CC(C(C)(C)CC(C)(C)C)=CC=C1OCCOCC[N+](C)(C)CC1=CC=CC=C1 UREZNYTWGJKWBI-UHFFFAOYSA-M 0.000 description 2
- 239000005711 Benzoic acid Substances 0.000 description 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N Caprylic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 2
- 229940105329 Carboxymethylcellulose Drugs 0.000 description 2
- LZZYPRNAOMGNLH-UHFFFAOYSA-M Cetrimonium bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C LZZYPRNAOMGNLH-UHFFFAOYSA-M 0.000 description 2
- 229920002261 Corn starch Polymers 0.000 description 2
- 229920002785 Croscarmellose sodium Polymers 0.000 description 2
- HPXRVTGHNJAIIH-UHFFFAOYSA-N Cyclohexanol Chemical compound OC1CCCCC1 HPXRVTGHNJAIIH-UHFFFAOYSA-N 0.000 description 2
- GZCGUPFRVQAUEE-KCDKBNATSA-N D-(+)-Galactose Natural products OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C=O GZCGUPFRVQAUEE-KCDKBNATSA-N 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N D-sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- DIOQZVSQGTUSAI-UHFFFAOYSA-N Decane Chemical compound CCCCCCCCCC DIOQZVSQGTUSAI-UHFFFAOYSA-N 0.000 description 2
- GHVNFZFCNZKVNT-UHFFFAOYSA-N Decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 2
- 229960003887 Dichlorophen Drugs 0.000 description 2
- MDNWOSOZYLHTCG-UHFFFAOYSA-N Dichlorophene Chemical compound OC1=CC=C(Cl)C=C1CC1=CC(Cl)=CC=C1O MDNWOSOZYLHTCG-UHFFFAOYSA-N 0.000 description 2
- SNRUBQQJIBEYMU-UHFFFAOYSA-N Dodecane Chemical compound CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 description 2
- 239000001692 EU approved anti-caking agent Substances 0.000 description 2
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Exidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 2
- BJHIKXHVCXFQLS-UYFOZJQFSA-N Fructose Natural products OC[C@@H](O)[C@@H](O)[C@H](O)C(=O)CO BJHIKXHVCXFQLS-UYFOZJQFSA-N 0.000 description 2
- 241000223221 Fusarium oxysporum Species 0.000 description 2
- RGHNJXZEOKUKBD-SQOUGZDYSA-N Gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 2
- JFCQEDHGNNZCLN-UHFFFAOYSA-N Glutaric acid Chemical compound OC(=O)CCCC(O)=O JFCQEDHGNNZCLN-UHFFFAOYSA-N 0.000 description 2
- FUZZWVXGSFPDMH-UHFFFAOYSA-N Hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 description 2
- 241000238631 Hexapoda Species 0.000 description 2
- FUWUEFKEXZQKKA-UHFFFAOYSA-N Hinokitiol Chemical compound CC(C)C=1C=CC=C(O)C(=O)C=1 FUWUEFKEXZQKKA-UHFFFAOYSA-N 0.000 description 2
- CBFCDTFDPHXCNY-UHFFFAOYSA-N Icosane Chemical compound CCCCCCCCCCCCCCCCCCCC CBFCDTFDPHXCNY-UHFFFAOYSA-N 0.000 description 2
- RAXXELZNTBOGNW-UHFFFAOYSA-N Imidazole Chemical compound C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 description 2
- WYVVKGNFXHOCQV-UHFFFAOYSA-N Iodopropynyl butylcarbamate Chemical compound CCCCNC(=O)OCC#CI WYVVKGNFXHOCQV-UHFFFAOYSA-N 0.000 description 2
- 229920000126 Latex Polymers 0.000 description 2
- PYIDGJJWBIBVIA-UYTYNIKBSA-N Lauryl glucoside Chemical compound CCCCCCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O PYIDGJJWBIBVIA-UYTYNIKBSA-N 0.000 description 2
- 229920001732 Lignosulfonate Polymers 0.000 description 2
- IIPYXGDZVMZOAP-UHFFFAOYSA-N Lithium nitrate Chemical compound [Li+].[O-][N+]([O-])=O IIPYXGDZVMZOAP-UHFFFAOYSA-N 0.000 description 2
- OAIJSZIZWZSQBC-LWRKPGOESA-N Lycopene Natural products CC(C)=CCC\C(C)=C/C=C/C(/C)=C\C=C\C(\C)=C/C=C/C=C(/C)\C=C\C=C(\C)/C=C/C=C(/C)CCC=C(C)C OAIJSZIZWZSQBC-LWRKPGOESA-N 0.000 description 2
- GUBGYTABKSRVRQ-YOLKTULGSA-N Maltose Natural products O([C@@H]1[C@H](O)[C@@H](O)[C@H](O)O[C@H]1CO)[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 GUBGYTABKSRVRQ-YOLKTULGSA-N 0.000 description 2
- HCZKYJDFEPMADG-TXEJJXNPSA-N Masoprocol Chemical compound C([C@H](C)[C@H](C)CC=1C=C(O)C(O)=CC=1)C1=CC=C(O)C(O)=C1 HCZKYJDFEPMADG-TXEJJXNPSA-N 0.000 description 2
- FEWJPZIEWOKRBE-XIXRPRMCSA-N Mesotartaric acid Chemical compound OC(=O)[C@@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-XIXRPRMCSA-N 0.000 description 2
- ARIWANIATODDMH-UHFFFAOYSA-N Monolaurin Chemical compound CCCCCCCCCCCC(=O)OCC(O)CO ARIWANIATODDMH-UHFFFAOYSA-N 0.000 description 2
- QPCDCPDFJACHGM-UHFFFAOYSA-N N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(=O)O)CCN(CC(O)=O)CC(O)=O QPCDCPDFJACHGM-UHFFFAOYSA-N 0.000 description 2
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Natural products C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 description 2
- LQERIDTXQFOHKA-UHFFFAOYSA-N Nonadecane Chemical compound CCCCCCCCCCCCCCCCCCC LQERIDTXQFOHKA-UHFFFAOYSA-N 0.000 description 2
- BKIMMITUMNQMOS-UHFFFAOYSA-N Nonane Chemical compound CCCCCCCCC BKIMMITUMNQMOS-UHFFFAOYSA-N 0.000 description 2
- 229940116542 OTHER NUTRIENTS in ATC Drugs 0.000 description 2
- YCOZIPAWZNQLMR-UHFFFAOYSA-N Pentadecane Chemical compound CCCCCCCCCCCCCCC YCOZIPAWZNQLMR-UHFFFAOYSA-N 0.000 description 2
- 229960003330 Pentetic Acid Drugs 0.000 description 2
- XNGIFLGASWRNHJ-UHFFFAOYSA-N Phthalic acid Chemical compound OC(=O)C1=CC=CC=C1C(O)=O XNGIFLGASWRNHJ-UHFFFAOYSA-N 0.000 description 2
- 239000004952 Polyamide Substances 0.000 description 2
- 229920001213 Polysorbate 20 Polymers 0.000 description 2
- 229920001214 Polysorbate 60 Polymers 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- 229940069338 Potassium Sorbate Drugs 0.000 description 2
- CHHHXKFHOYLYRE-STWYSWDKSA-M Potassium sorbate Chemical compound [K+].C\C=C\C=C\C([O-])=O CHHHXKFHOYLYRE-STWYSWDKSA-M 0.000 description 2
- OTYBMLCTZGSZBG-UHFFFAOYSA-L Potassium sulfate Chemical compound [K+].[K+].[O-]S([O-])(=O)=O OTYBMLCTZGSZBG-UHFFFAOYSA-L 0.000 description 2
- QELSKZZBTMNZEB-UHFFFAOYSA-N Propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 2
- WYTGDNHDOZPMIW-UHOFOFEASA-O Serpentine Natural products O=C(OC)C=1[C@@H]2[C@@H]([C@@H](C)OC=1)C[n+]1c(c3[nH]c4c(c3cc1)cccc4)C2 WYTGDNHDOZPMIW-UHOFOFEASA-O 0.000 description 2
- GCLGEJMYGQKIIW-UHFFFAOYSA-H Sodium hexametaphosphate Chemical compound [Na]OP1(=O)OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])O1 GCLGEJMYGQKIIW-UHFFFAOYSA-H 0.000 description 2
- RYYKJJJTJZKILX-UHFFFAOYSA-M Sodium stearate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC([O-])=O RYYKJJJTJZKILX-UHFFFAOYSA-M 0.000 description 2
- 229920001304 Solutol HS 15 Polymers 0.000 description 2
- SFVFIFLLYFPGHH-UHFFFAOYSA-M Stearalkonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 SFVFIFLLYFPGHH-UHFFFAOYSA-M 0.000 description 2
- PJANXHGTPQOBST-VAWYXSNFSA-N Stilbene Natural products C=1C=CC=CC=1/C=C/C1=CC=CC=C1 PJANXHGTPQOBST-VAWYXSNFSA-N 0.000 description 2
- CZMRCDWAGMRECN-GDQSFJPYSA-N Sucrose Natural products O([C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O1)[C@@]1(CO)[C@H](O)[C@@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-GDQSFJPYSA-N 0.000 description 2
- POOSGDOYLQNASK-UHFFFAOYSA-N Tetracosane Chemical compound CCCCCCCCCCCCCCCCCCCCCCCC POOSGDOYLQNASK-UHFFFAOYSA-N 0.000 description 2
- BGHCVCJVXZWKCC-UHFFFAOYSA-N Tetradecane Chemical compound CCCCCCCCCCCCCC BGHCVCJVXZWKCC-UHFFFAOYSA-N 0.000 description 2
- WGTYBPLFGIVFAS-UHFFFAOYSA-M Tetramethylammonium hydroxide Chemical compound [OH-].C[N+](C)(C)C WGTYBPLFGIVFAS-UHFFFAOYSA-M 0.000 description 2
- 229920001615 Tragacanth Polymers 0.000 description 2
- FPKOPBFLPLFWAD-UHFFFAOYSA-N Trinitrotoluene Chemical compound CC1=CC=C([N+]([O-])=O)C([N+]([O-])=O)=C1[N+]([O-])=O FPKOPBFLPLFWAD-UHFFFAOYSA-N 0.000 description 2
- RSJKGSCJYJTIGS-UHFFFAOYSA-N Undecane Chemical compound CCCCCCCCCCC RSJKGSCJYJTIGS-UHFFFAOYSA-N 0.000 description 2
- SRBFZHDQGSBBOR-SQOUGZDYSA-N Xylose Natural products O[C@@H]1CO[C@@H](O)[C@@H](O)[C@@H]1O SRBFZHDQGSBBOR-SQOUGZDYSA-N 0.000 description 2
- NWGKJDSIEKMTRX-BFWOXRRGSA-N [(2R)-2-[(3R,4S)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] (Z)-octadec-9-enoate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)C1OC[C@H](O)[C@H]1O NWGKJDSIEKMTRX-BFWOXRRGSA-N 0.000 description 2
- 239000000642 acaricide Substances 0.000 description 2
- 150000001242 acetic acid derivatives Chemical class 0.000 description 2
- 238000007792 addition Methods 0.000 description 2
- 239000008272 agar Substances 0.000 description 2
- 235000010419 agar Nutrition 0.000 description 2
- 239000000783 alginic acid Substances 0.000 description 2
- 229960001126 alginic acid Drugs 0.000 description 2
- 125000001931 aliphatic group Chemical group 0.000 description 2
- 150000001338 aliphatic hydrocarbons Chemical class 0.000 description 2
- 150000001339 alkali metal compounds Chemical class 0.000 description 2
- 150000003973 alkyl amines Chemical class 0.000 description 2
- 150000001280 alpha hydroxy acids Chemical class 0.000 description 2
- ANVAOWXLWRTKGA-HLLMEWEMSA-N alpha-Carotene Natural products C(=C\C=C\C=C(/C=C/C=C(\C=C\C=1C(C)(C)CCCC=1C)/C)\C)(\C=C\C=C(/C=C/[C@H]1C(C)=CCCC1(C)C)\C)/C ANVAOWXLWRTKGA-HLLMEWEMSA-N 0.000 description 2
- 230000000845 anti-microbial Effects 0.000 description 2
- 239000003125 aqueous solvent Substances 0.000 description 2
- 125000003289 ascorbyl group Chemical class [H]O[C@@]([H])(C([H])([H])O*)[C@@]1([H])OC(=O)C(O*)=C1O* 0.000 description 2
- 230000001580 bacterial Effects 0.000 description 2
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N benzohydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 description 2
- 235000010233 benzoic acid Nutrition 0.000 description 2
- 150000008366 benzophenones Chemical class 0.000 description 2
- 230000003115 biocidal Effects 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N butylene glycol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 2
- YYRMJZQKEFZXMX-UHFFFAOYSA-N calcium;phosphoric acid Chemical class [Ca+2].OP(O)(O)=O.OP(O)(O)=O YYRMJZQKEFZXMX-UHFFFAOYSA-N 0.000 description 2
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 2
- 150000001735 carboxylic acids Chemical class 0.000 description 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 2
- 239000005018 casein Substances 0.000 description 2
- 235000021240 caseins Nutrition 0.000 description 2
- 239000000460 chlorine Substances 0.000 description 2
- 229910052801 chlorine Inorganic materials 0.000 description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 230000003750 conditioning Effects 0.000 description 2
- 239000008120 corn starch Substances 0.000 description 2
- 230000000994 depressed Effects 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- KARVSHNNUWMXFO-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane;hydrate Chemical compound O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Al]O[Al]=O KARVSHNNUWMXFO-UHFFFAOYSA-N 0.000 description 2
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N edta Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 2
- 238000001125 extrusion Methods 0.000 description 2
- 150000002191 fatty alcohols Chemical class 0.000 description 2
- 239000002509 fulvic acid Substances 0.000 description 2
- 229940095100 fulvic acid Drugs 0.000 description 2
- 244000053095 fungal pathogens Species 0.000 description 2
- 150000002314 glycerols Chemical class 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- FNAZRRHPUDJQCJ-UHFFFAOYSA-N henicosane Chemical compound CCCCCCCCCCCCCCCCCCCCC FNAZRRHPUDJQCJ-UHFFFAOYSA-N 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 239000004816 latex Substances 0.000 description 2
- 229940048848 lauryl glucoside Drugs 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- INHCSSUBVCNVSK-UHFFFAOYSA-L lithium sulfate Chemical compound [Li+].[Li+].[O-]S([O-])(=O)=O INHCSSUBVCNVSK-UHFFFAOYSA-L 0.000 description 2
- 239000011777 magnesium Substances 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 229940099690 malic acid Drugs 0.000 description 2
- 235000011090 malic acid Nutrition 0.000 description 2
- 229910052618 mica group Inorganic materials 0.000 description 2
- 238000003801 milling Methods 0.000 description 2
- 239000002480 mineral oil Substances 0.000 description 2
- 235000010446 mineral oil Nutrition 0.000 description 2
- 150000007522 mineralic acids Chemical class 0.000 description 2
- 229910000403 monosodium phosphate Inorganic materials 0.000 description 2
- 235000019799 monosodium phosphate Nutrition 0.000 description 2
- 229910052901 montmorillonite Inorganic materials 0.000 description 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N n-butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
- SECXISVLQFMRJM-UHFFFAOYSA-N n-methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 description 2
- PSZYNBSKGUBXEH-UHFFFAOYSA-N naphthalene-1-sulfonic acid Chemical compound C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 PSZYNBSKGUBXEH-UHFFFAOYSA-N 0.000 description 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- MGFYIUFZLHCRTH-UHFFFAOYSA-N nitrilotriacetic acid Chemical compound OC(=O)CN(CC(O)=O)CC(O)=O MGFYIUFZLHCRTH-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 239000002736 nonionic surfactant Substances 0.000 description 2
- KBPLFHHGFOOTCA-UHFFFAOYSA-N octanol Chemical compound CCCCCCCCO KBPLFHHGFOOTCA-UHFFFAOYSA-N 0.000 description 2
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid group Chemical group C(CCCCCCC\C=C/CCCCCCCC)(=O)O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 2
- 150000002894 organic compounds Chemical class 0.000 description 2
- 238000010422 painting Methods 0.000 description 2
- 235000010987 pectin Nutrition 0.000 description 2
- 239000001814 pectin Substances 0.000 description 2
- 229920001277 pectin Polymers 0.000 description 2
- YKNWIILGEFFOPE-UHFFFAOYSA-N pentacosane Chemical compound CCCCCCCCCCCCCCCCCCCCCCCCC YKNWIILGEFFOPE-UHFFFAOYSA-N 0.000 description 2
- 239000010451 perlite Substances 0.000 description 2
- 235000019362 perlite Nutrition 0.000 description 2
- 239000003209 petroleum derivative Substances 0.000 description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 2
- 229920002647 polyamide Polymers 0.000 description 2
- 229920005646 polycarboxylate Polymers 0.000 description 2
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 2
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 2
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 2
- 229920000053 polysorbate 80 Polymers 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 2
- 235000015320 potassium carbonate Nutrition 0.000 description 2
- 239000001103 potassium chloride Substances 0.000 description 2
- 235000011164 potassium chloride Nutrition 0.000 description 2
- 235000010333 potassium nitrate Nutrition 0.000 description 2
- 239000004323 potassium nitrate Substances 0.000 description 2
- 235000010241 potassium sorbate Nutrition 0.000 description 2
- 239000004302 potassium sorbate Substances 0.000 description 2
- 229910052939 potassium sulfate Inorganic materials 0.000 description 2
- 235000011151 potassium sulphates Nutrition 0.000 description 2
- 230000002035 prolonged Effects 0.000 description 2
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 2
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 description 2
- 229960003415 propylparaben Drugs 0.000 description 2
- 239000005871 repellent Substances 0.000 description 2
- 230000002940 repellent Effects 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 230000000717 retained Effects 0.000 description 2
- IKGXIBQEEMLURG-NVPNHPEKSA-N rutin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-NVPNHPEKSA-N 0.000 description 2
- 229960004555 rutoside Drugs 0.000 description 2
- 229960004889 salicylic acid Drugs 0.000 description 2
- BUGBHKTXTAQXES-UHFFFAOYSA-N selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 2
- 229910052711 selenium Inorganic materials 0.000 description 2
- 239000011669 selenium Substances 0.000 description 2
- 150000004760 silicates Chemical class 0.000 description 2
- 235000012239 silicon dioxide Nutrition 0.000 description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L sodium carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 2
- 235000019982 sodium hexametaphosphate Nutrition 0.000 description 2
- 229940045885 sodium lauroyl sarcosinate Drugs 0.000 description 2
- 235000010344 sodium nitrate Nutrition 0.000 description 2
- 239000004317 sodium nitrate Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000000638 solvent extraction Methods 0.000 description 2
- 235000012424 soybean oil Nutrition 0.000 description 2
- 239000003549 soybean oil Substances 0.000 description 2
- QIQXTHQIDYTFRH-UHFFFAOYSA-M stearate Chemical class CCCCCCCCCCCCCCCCCC([O-])=O QIQXTHQIDYTFRH-UHFFFAOYSA-M 0.000 description 2
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 239000001384 succinic acid Substances 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 125000001273 sulfonato group Chemical group [O-]S(*)(=O)=O 0.000 description 2
- 239000002426 superphosphate Substances 0.000 description 2
- 239000011975 tartaric acid Substances 0.000 description 2
- 229960001367 tartaric acid Drugs 0.000 description 2
- 235000002906 tartaric acid Nutrition 0.000 description 2
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 description 2
- PIZNQHDTOZMVBH-UHFFFAOYSA-N thionylimide Chemical class N=S=O PIZNQHDTOZMVBH-UHFFFAOYSA-N 0.000 description 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 2
- 238000005809 transesterification reaction Methods 0.000 description 2
- FIGVVZUWCLSUEI-UHFFFAOYSA-N tricosane Chemical compound CCCCCCCCCCCCCCCCCCCCCCC FIGVVZUWCLSUEI-UHFFFAOYSA-N 0.000 description 2
- SZYJELPVAFJOGJ-UHFFFAOYSA-N trimethylamine hydrochloride Chemical compound Cl.CN(C)C SZYJELPVAFJOGJ-UHFFFAOYSA-N 0.000 description 2
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 2
- 235000019354 vermiculite Nutrition 0.000 description 2
- 229920001285 xanthan gum Polymers 0.000 description 2
- 235000010493 xanthan gum Nutrition 0.000 description 2
- 239000000230 xanthan gum Substances 0.000 description 2
- 229940082509 xanthan gum Drugs 0.000 description 2
- 239000010457 zeolite Substances 0.000 description 2
- WQZGKKKJIJFFOK-PHYPRBDBSA-N α-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 2
- 239000004711 α-olefin Substances 0.000 description 2
- 229930007845 β-thujaplicin Natural products 0.000 description 2
- NJGIRBISCGPRPF-KXQOOQHDSA-N (2-aminoethoxy)[(2R)-2-(icosanoyloxy)-3-(pentadecanoyloxy)propoxy]phosphinic acid Chemical compound CCCCCCCCCCCCCCCCCCCC(=O)O[C@@H](COP(O)(=O)OCCN)COC(=O)CCCCCCCCCCCCCC NJGIRBISCGPRPF-KXQOOQHDSA-N 0.000 description 1
- TYQCGQRIZGCHNB-DUZGATOHSA-N (2R)-2-[(1R)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one Chemical compound OC[C@@H](O)[C@H]1OC(O)=C(O)C1=O TYQCGQRIZGCHNB-DUZGATOHSA-N 0.000 description 1
- DYIOSHGVFJTOAR-JGWLITMVSA-N (2R,3R,4S,5R)-6-sulfanylhexane-1,2,3,4,5-pentol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CS DYIOSHGVFJTOAR-JGWLITMVSA-N 0.000 description 1
- HEGSGKPQLMEBJL-RQICVUQASA-N (2R,3S,4S,5R)-2-(hydroxymethyl)-6-octoxyoxane-3,4,5-triol Chemical compound CCCCCCCCOC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HEGSGKPQLMEBJL-RQICVUQASA-N 0.000 description 1
- JDRSMPFHFNXQRB-CMTNHCDUSA-N (2R,4S,6R)-2-decoxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound CCCCCCCCCCO[C@@H]1O[C@H](CO)C(O)[C@H](O)C1O JDRSMPFHFNXQRB-CMTNHCDUSA-N 0.000 description 1
- IZFHEQBZOYJLPK-SSDOTTSWSA-N (R)-dihydrolipoic acid Chemical compound OC(=O)CCCC[C@@H](S)CCS IZFHEQBZOYJLPK-SSDOTTSWSA-N 0.000 description 1
- BMRWNKZVCUKKSR-UHFFFAOYSA-N 1,2-Butanediol Chemical compound CCC(O)CO BMRWNKZVCUKKSR-UHFFFAOYSA-N 0.000 description 1
- JLHMJWHSBYZWJJ-UHFFFAOYSA-N 1,2-thiazole 1-oxide Chemical class O=S1C=CC=N1 JLHMJWHSBYZWJJ-UHFFFAOYSA-N 0.000 description 1
- TUBQDCKAWGHZPF-UHFFFAOYSA-N 1,3-benzothiazol-2-ylsulfanylmethyl thiocyanate Chemical compound C1=CC=C2SC(SCSC#N)=NC2=C1 TUBQDCKAWGHZPF-UHFFFAOYSA-N 0.000 description 1
- LEYHLVOBHJAXIC-UHFFFAOYSA-N 1,3-bis(2-ethylhexyl)-2-methyl-1,3-diazinan-5-amine Chemical compound CCCCC(CC)CN1CC(N)CN(CC(CC)CCCC)C1C LEYHLVOBHJAXIC-UHFFFAOYSA-N 0.000 description 1
- OXLXSOPFNVKUMU-UHFFFAOYSA-N 1,4-dioctoxy-1,4-dioxobutane-2-sulfonic acid Chemical compound CCCCCCCCOC(=O)CC(S(O)(=O)=O)C(=O)OCCCCCCCC OXLXSOPFNVKUMU-UHFFFAOYSA-N 0.000 description 1
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 1
- ALQSHHUCVQOPAS-UHFFFAOYSA-N 1,5-Pentanediol Chemical compound OCCCCCO ALQSHHUCVQOPAS-UHFFFAOYSA-N 0.000 description 1
- IQXJCCZJOIKIAD-UHFFFAOYSA-N 1-(2-methoxyethoxy)hexadecane Chemical compound CCCCCCCCCCCCCCCCOCCOC IQXJCCZJOIKIAD-UHFFFAOYSA-N 0.000 description 1
- DDTTVGRQFBNYJD-UHFFFAOYSA-N 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-5-ylmethyl)pentan-3-ol Chemical compound N=1C=NNC=1CC(O)(C(C)(C)C)CCC1=CC=C(Cl)C=C1 DDTTVGRQFBNYJD-UHFFFAOYSA-N 0.000 description 1
- VETPHHXZEJAYOB-UHFFFAOYSA-N 1-N,4-N-dinaphthalen-2-ylbenzene-1,4-diamine Chemical compound C1=CC=CC2=CC(NC=3C=CC(NC=4C=C5C=CC=CC5=CC=4)=CC=3)=CC=C21 VETPHHXZEJAYOB-UHFFFAOYSA-N 0.000 description 1
- HPFDGTFXAVIVTH-UHFFFAOYSA-N 1-[1-(1-methoxypropan-2-yloxy)propan-2-yloxy]propan-2-ol Chemical compound COCC(C)OCC(C)OCC(C)O HPFDGTFXAVIVTH-UHFFFAOYSA-N 0.000 description 1
- DURPTKYDGMDSBL-UHFFFAOYSA-N 1-butoxybutane Chemical compound CCCCOCCCC DURPTKYDGMDSBL-UHFFFAOYSA-N 0.000 description 1
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 description 1
- ARXJGSRGQADJSQ-UHFFFAOYSA-N 1-methoxypropan-2-ol Chemical compound COCC(C)O ARXJGSRGQADJSQ-UHFFFAOYSA-N 0.000 description 1
- HBXWUCXDUUJDRB-UHFFFAOYSA-N 1-octadecoxyoctadecane Chemical compound CCCCCCCCCCCCCCCCCCOCCCCCCCCCCCCCCCCCC HBXWUCXDUUJDRB-UHFFFAOYSA-N 0.000 description 1
- OAAZUWWNSYWWHG-UHFFFAOYSA-N 1-phenoxypropan-1-ol Chemical compound CCC(O)OC1=CC=CC=C1 OAAZUWWNSYWWHG-UHFFFAOYSA-N 0.000 description 1
- HDQXEDYPJZYWPY-UHFFFAOYSA-N 2,2,3-trihydroxy-1-phenylbutan-1-one Chemical compound CC(O)C(O)(O)C(=O)C1=CC=CC=C1 HDQXEDYPJZYWPY-UHFFFAOYSA-N 0.000 description 1
- RKMGAJGJIURJSJ-UHFFFAOYSA-N 2,2,6,6-Tetramethylpiperidine Substances CC1(C)CCCC(C)(C)N1 RKMGAJGJIURJSJ-UHFFFAOYSA-N 0.000 description 1
- WAZOXQOFCQKLFT-QXMHVHEDSA-N 2,2-bis(hydroxymethyl)butyl (Z)-octadec-9-enoate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(CC)(CO)CO WAZOXQOFCQKLFT-QXMHVHEDSA-N 0.000 description 1
- VCVWNAWLJLMCBE-UHFFFAOYSA-N 2,2-dimethyldecanamide Chemical compound CCCCCCCCC(C)(C)C(N)=O VCVWNAWLJLMCBE-UHFFFAOYSA-N 0.000 description 1
- FITYLPBGJXBNCW-UHFFFAOYSA-N 2,2-dimethyloctanamide Chemical compound CCCCCCC(C)(C)C(N)=O FITYLPBGJXBNCW-UHFFFAOYSA-N 0.000 description 1
- SQRDRPSVGROPHX-UHFFFAOYSA-N 2,3,3-triiodoprop-2-en-1-ol Chemical compound OCC(I)=C(I)I SQRDRPSVGROPHX-UHFFFAOYSA-N 0.000 description 1
- YABHQQLSFUHFHD-UHFFFAOYSA-N 2,3-dihydro-1,2-thiazole 1-oxide Chemical class O=S1NCC=C1 YABHQQLSFUHFHD-UHFFFAOYSA-N 0.000 description 1
- DBHODFSFBXJZNY-UHFFFAOYSA-N 2,4-Dichlorobenzyl alcohol Chemical compound OCC1=CC=C(Cl)C=C1Cl DBHODFSFBXJZNY-UHFFFAOYSA-N 0.000 description 1
- OVSKIKFHRZPJSS-UHFFFAOYSA-N 2,4-Dichlorophenoxyacetic acid Chemical compound OC(=O)COC1=CC=C(Cl)C=C1Cl OVSKIKFHRZPJSS-UHFFFAOYSA-N 0.000 description 1
- MCPKSFINULVDNX-UHFFFAOYSA-N 2-(benzotriazol-2-yl)-4-methylphenol Chemical compound CC1=CC=C(O)C(N2N=C3C=CC=CC3=N2)=C1 MCPKSFINULVDNX-UHFFFAOYSA-N 0.000 description 1
- ITLDHFORLZTRJI-UHFFFAOYSA-N 2-(benzotriazol-2-yl)-5-octoxyphenol Chemical compound OC1=CC(OCCCCCCCC)=CC=C1N1N=C2C=CC=CC2=N1 ITLDHFORLZTRJI-UHFFFAOYSA-N 0.000 description 1
- RTCKBXOBRZWQNY-UHFFFAOYSA-N 2-(chloromethyl)-1,2-thiazol-3-one Chemical compound ClCN1SC=CC1=O RTCKBXOBRZWQNY-UHFFFAOYSA-N 0.000 description 1
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-Methyl-2,4-pentanediol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 description 1
- LLEMOWNGBBNAJR-UHFFFAOYSA-N 2-Phenylphenol Chemical compound OC1=CC=CC=C1C1=CC=CC=C1 LLEMOWNGBBNAJR-UHFFFAOYSA-N 0.000 description 1
- UCYLROVJSUACAD-UHFFFAOYSA-N 2-[2,3-bis(2-hydroxyethoxy)propoxy]ethanol Chemical compound OCCOCC(OCCO)COCCO UCYLROVJSUACAD-UHFFFAOYSA-N 0.000 description 1
- GCSJOZFHZGHGTJ-UHFFFAOYSA-N 2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl formate Chemical compound O=COCCOCC(OCCO)C1OCC(OCCO)C1OCCO GCSJOZFHZGHGTJ-UHFFFAOYSA-N 0.000 description 1
- LBCZOTMMGHGTPH-UHFFFAOYSA-N 2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethanol Chemical compound CC(C)(C)CC(C)(C)C1=CC=C(OCCOCCO)C=C1 LBCZOTMMGHGTPH-UHFFFAOYSA-N 0.000 description 1
- URDCARMUOSMFFI-UHFFFAOYSA-N 2-[2-[bis(carboxymethyl)amino]ethyl-(2-hydroxyethyl)amino]acetic acid Chemical compound OCCN(CC(O)=O)CCN(CC(O)=O)CC(O)=O URDCARMUOSMFFI-UHFFFAOYSA-N 0.000 description 1
- JYCQQPHGFMYQCF-UHFFFAOYSA-N 2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethanol Chemical compound CC(C)(C)CC(C)(C)C1=CC=C(OCCO)C=C1 JYCQQPHGFMYQCF-UHFFFAOYSA-N 0.000 description 1
- VUKAUDKDFVSVFT-UHFFFAOYSA-N 2-[6-[4,5-bis(2-hydroxypropoxy)-2-(2-hydroxypropoxymethyl)-6-methoxyoxan-3-yl]oxy-4,5-dimethoxy-2-(methoxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)-5-methoxyoxane-3,4-diol Chemical compound COC1C(OC)C(OC2C(C(O)C(OC)C(CO)O2)O)C(COC)OC1OC1C(COCC(C)O)OC(OC)C(OCC(C)O)C1OCC(C)O VUKAUDKDFVSVFT-UHFFFAOYSA-N 0.000 description 1
- WJLVQTJZDCGNJN-UHFFFAOYSA-N 2-[6-[[amino-[[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine;hydron;dichloride Chemical compound Cl.Cl.C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 WJLVQTJZDCGNJN-UHFFFAOYSA-N 0.000 description 1
- LRYZPFWEZHSTHD-HEFFAWAOSA-O 2-[[(E,2S,3R)-2-formamido-3-hydroxyoctadec-4-enoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium Chemical class CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](NC=O)COP(O)(=O)OCC[N+](C)(C)C LRYZPFWEZHSTHD-HEFFAWAOSA-O 0.000 description 1
- JYXGIOKAKDAARW-UHFFFAOYSA-N 2-[carboxymethyl(2-hydroxyethyl)amino]acetic acid Chemical compound OCCN(CC(O)=O)CC(O)=O JYXGIOKAKDAARW-UHFFFAOYSA-N 0.000 description 1
- ZAMOVMHWSVVCQD-UHFFFAOYSA-N 2-benzyl-3-chlorophenol Chemical compound OC1=CC=CC(Cl)=C1CC1=CC=CC=C1 ZAMOVMHWSVVCQD-UHFFFAOYSA-N 0.000 description 1
- AHKRMDMQOAEIKN-UHFFFAOYSA-N 2-benzyl-3-methylphenol Chemical compound CC1=CC=CC(O)=C1CC1=CC=CC=C1 AHKRMDMQOAEIKN-UHFFFAOYSA-N 0.000 description 1
- SRHRIZPRFAUHCX-UHFFFAOYSA-N 2-bromo-1-nitropropane-1,3-diol Chemical compound OCC(Br)C(O)[N+]([O-])=O SRHRIZPRFAUHCX-UHFFFAOYSA-N 0.000 description 1
- TYBHZVUFOINFDV-UHFFFAOYSA-N 2-bromo-6-[(3-bromo-5-chloro-2-hydroxyphenyl)methyl]-4-chlorophenol Chemical compound OC1=C(Br)C=C(Cl)C=C1CC1=CC(Cl)=CC(Br)=C1O TYBHZVUFOINFDV-UHFFFAOYSA-N 0.000 description 1
- DJENHUUHOGXXCB-UHFFFAOYSA-N 2-butyl-6-methoxyphenol Chemical compound CCCCC1=CC=CC(OC)=C1O DJENHUUHOGXXCB-UHFFFAOYSA-N 0.000 description 1
- KIHBGTRZFAVZRV-UHFFFAOYSA-N 2-hydroxystearic acid Chemical compound CCCCCCCCCCCCCCCCC(O)C(O)=O KIHBGTRZFAVZRV-UHFFFAOYSA-N 0.000 description 1
- XCQPQCJWSNLGLM-UHFFFAOYSA-N 2-methoxy-4-prop-1-enylphenol;zinc Chemical compound [Zn].COC1=CC(C=CC)=CC=C1O XCQPQCJWSNLGLM-UHFFFAOYSA-N 0.000 description 1
- ZHCGVAXFRLLEFW-UHFFFAOYSA-N 2-methyl-3-(prop-2-enoylamino)propane-1-sulfonic acid Chemical compound OS(=O)(=O)CC(C)CNC(=O)C=C ZHCGVAXFRLLEFW-UHFFFAOYSA-N 0.000 description 1
- QEYKLZYTRRKMAT-UHFFFAOYSA-N 2-methyl-3H-1,2-thiazole 1-oxide Chemical compound CN1CC=CS1=O QEYKLZYTRRKMAT-UHFFFAOYSA-N 0.000 description 1
- TUUQYMUMWQTNPZ-UHFFFAOYSA-N 2-oxo-1H-quinoline-5-sulfonic acid Chemical compound OS(=O)(=O)C1=CC=CC2=NC(O)=CC=C21 TUUQYMUMWQTNPZ-UHFFFAOYSA-N 0.000 description 1
- TYEYBOSBBBHJIV-UHFFFAOYSA-M 2-oxobutanoate Chemical compound CCC(=O)C([O-])=O TYEYBOSBBBHJIV-UHFFFAOYSA-M 0.000 description 1
- YQEMORVAKMFKLG-UHFFFAOYSA-N 2-stearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC(CO)CO YQEMORVAKMFKLG-UHFFFAOYSA-N 0.000 description 1
- CAPNUXMLPONECZ-UHFFFAOYSA-M 3-(3,5-ditert-butyl-2-hydroxyphenyl)propanoate Chemical compound CC(C)(C)C1=CC(CCC([O-])=O)=C(O)C(C(C)(C)C)=C1 CAPNUXMLPONECZ-UHFFFAOYSA-M 0.000 description 1
- PJUIMOJAAPLTRJ-UHFFFAOYSA-N 3-Mercaptopropane-1,2-diol Chemical compound OCC(O)CS PJUIMOJAAPLTRJ-UHFFFAOYSA-N 0.000 description 1
- WXTBYSIPOKXCPM-UHFFFAOYSA-N 3-acetyl-1,3-thiazolidine-4-carboxylic acid Chemical compound CC(=O)N1CSCC1C(O)=O WXTBYSIPOKXCPM-UHFFFAOYSA-N 0.000 description 1
- ZSMKZRXHCAOERY-UHFFFAOYSA-N 3-bromo-4-[6-(2-bromo-4-carbamimidoylphenoxy)hexoxy]benzenecarboximidamide Chemical compound BrC1=CC(C(=N)N)=CC=C1OCCCCCCOC1=CC=C(C(N)=N)C=C1Br ZSMKZRXHCAOERY-UHFFFAOYSA-N 0.000 description 1
- AYKYXWQEBUNJCN-UHFFFAOYSA-N 3-methylfuran-2,5-dione Chemical compound CC1=CC(=O)OC1=O AYKYXWQEBUNJCN-UHFFFAOYSA-N 0.000 description 1
- GUQMDNQYMMRJPY-UHFFFAOYSA-N 4,4-dimethyl-1,3-oxazolidine Chemical compound CC1(C)COCN1 GUQMDNQYMMRJPY-UHFFFAOYSA-N 0.000 description 1
- XXAXVMUWHZHZMJ-UHFFFAOYSA-N 4,5-dihydroxybenzene-1,3-disulfonic acid Chemical compound OC1=CC(S(O)(=O)=O)=CC(S(O)(=O)=O)=C1O XXAXVMUWHZHZMJ-UHFFFAOYSA-N 0.000 description 1
- NTDQQZYCCIDJRK-UHFFFAOYSA-N 4-octylphenol Chemical compound CCCCCCCCC1=CC=C(O)C=C1 NTDQQZYCCIDJRK-UHFFFAOYSA-N 0.000 description 1
- DBOSBRHMHBENLP-UHFFFAOYSA-N 4-tert-Butylphenyl salicylate Chemical compound C1=CC(C(C)(C)C)=CC=C1OC(=O)C1=CC=CC=C1O DBOSBRHMHBENLP-UHFFFAOYSA-N 0.000 description 1
- YJISHJVIRFPGGN-UHFFFAOYSA-N 5-[5-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxy-6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol Chemical compound O1C(CO)C(OC)C(O)C(O)C1OCC1C(OC2C(C(O)C(OC)C(CO)O2)O)C(O)C(O)C(OC2C(OC(C)C(O)C2O)CO)O1 YJISHJVIRFPGGN-UHFFFAOYSA-N 0.000 description 1
- CWSZBVAUYPTXTG-UHFFFAOYSA-N 5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol Chemical compound O1C(CO)C(OC)C(O)C(O)C1OCC1C(OC2C(C(O)C(OC)C(CO)O2)OCCO)C(O)C(O)C(OC2C(OC(C)C(O)C2O)CO)O1 CWSZBVAUYPTXTG-UHFFFAOYSA-N 0.000 description 1
- HQUNRTKPVPUNTG-UHFFFAOYSA-N 5-bromo-2-nitro-1,3-dioxane Chemical compound [O-][N+](=O)C1OCC(Br)CO1 HQUNRTKPVPUNTG-UHFFFAOYSA-N 0.000 description 1
- GCEASLRXAYXWRR-UHFFFAOYSA-N 6-bromo-2-[(3-bromo-6-chloro-2-hydroxyphenyl)methyl]-3-chlorophenol Chemical compound OC1=C(Br)C=CC(Cl)=C1CC1=C(O)C(Br)=CC=C1Cl GCEASLRXAYXWRR-UHFFFAOYSA-N 0.000 description 1
- KNAHARQHSZJURB-UHFFFAOYSA-N 6-propyl-2-thio-Uracil Chemical compound CCCC1=CC(=O)NC(=S)N1 KNAHARQHSZJURB-UHFFFAOYSA-N 0.000 description 1
- ZRCMGIXRGFOXNT-UHFFFAOYSA-N 7a-ethyl-1,3,5,7-tetrahydro-[1,3]oxazolo[3,4-c][1,3]oxazole Chemical compound C1OCN2COCC21CC ZRCMGIXRGFOXNT-UHFFFAOYSA-N 0.000 description 1
- 229940063953 AMMONIUM LAURYL SULFATE Drugs 0.000 description 1
- 229940022663 Acetate Drugs 0.000 description 1
- 229920002126 Acrylic acid copolymer Polymers 0.000 description 1
- WNLRTRBMVRJNCN-UHFFFAOYSA-N Adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 description 1
- 229910002012 Aerosil® Inorganic materials 0.000 description 1
- 235000002961 Aloe barbadensis Nutrition 0.000 description 1
- 240000005513 Aloe vera Species 0.000 description 1
- LFVGISIMTYGQHF-UHFFFAOYSA-N Ammonium dihydrogen phosphate Chemical compound [NH4+].OP(O)([O-])=O LFVGISIMTYGQHF-UHFFFAOYSA-N 0.000 description 1
- BTBJBAZGXNKLQC-UHFFFAOYSA-N Ammonium lauryl sulfate Chemical compound [NH4+].CCCCCCCCCCCCOS([O-])(=O)=O BTBJBAZGXNKLQC-UHFFFAOYSA-N 0.000 description 1
- DVARTQFDIMZBAA-UHFFFAOYSA-O Ammonium nitrate Chemical compound [NH4+].[O-][N+]([O-])=O DVARTQFDIMZBAA-UHFFFAOYSA-O 0.000 description 1
- ORBBVPFDROYXQS-UHFFFAOYSA-N Ammonium perfluorononanoate Chemical compound N.OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F ORBBVPFDROYXQS-UHFFFAOYSA-N 0.000 description 1
- 229920000945 Amylopectin Polymers 0.000 description 1
- WMGFVAGNIYUEEP-WUYNJSITSA-N Amylopectin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)O[C@H](OC[C@@H]2[C@H]([C@H](O)[C@@H](O)[C@@H](O[C@@H]3[C@H](O[C@H](O)[C@H](O)[C@H]3O)CO)O2)O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@H]1O WMGFVAGNIYUEEP-WUYNJSITSA-N 0.000 description 1
- 229920000856 Amylose Polymers 0.000 description 1
- 229960000271 Arbutin Drugs 0.000 description 1
- 241000228212 Aspergillus Species 0.000 description 1
- 241000228245 Aspergillus niger Species 0.000 description 1
- 241001530056 Athelia rolfsii Species 0.000 description 1
- XHVAWZZCDCWGBK-WYRLRVFGSA-M Aurothioglucose Chemical compound OC[C@H]1O[C@H](S[Au])[C@H](O)[C@@H](O)[C@@H]1O XHVAWZZCDCWGBK-WYRLRVFGSA-M 0.000 description 1
- 229940073464 BENZODODECINIUM BROMIDE Drugs 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- YSJGOMATDFSEED-UHFFFAOYSA-M Behentrimonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCCCCCCCC[N+](C)(C)C YSJGOMATDFSEED-UHFFFAOYSA-M 0.000 description 1
- 229940075506 Behentrimonium chloride Drugs 0.000 description 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N Bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 1
- 229960001950 Benzethonium Chloride Drugs 0.000 description 1
- 229940050390 Benzoate Drugs 0.000 description 1
- KHSLHYAUZSPBIU-UHFFFAOYSA-M Benzododecinium bromide Chemical compound [Br-].CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 KHSLHYAUZSPBIU-UHFFFAOYSA-M 0.000 description 1
- IOJUPLGTWVMSFF-UHFFFAOYSA-N Benzothiazole Chemical class C1=CC=C2SC=NC2=C1 IOJUPLGTWVMSFF-UHFFFAOYSA-N 0.000 description 1
- 229960002747 Betacarotene Drugs 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical class OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- XVBRCOKDZVQYAY-UHFFFAOYSA-N Bronidox Chemical compound [O-][N+](=O)C1(Br)COCOC1 XVBRCOKDZVQYAY-UHFFFAOYSA-N 0.000 description 1
- CZBZUDVBLSSABA-UHFFFAOYSA-N Butylated hydroxyanisole Chemical compound COC1=CC=C(O)C(C(C)(C)C)=C1.COC1=CC=C(O)C=C1C(C)(C)C CZBZUDVBLSSABA-UHFFFAOYSA-N 0.000 description 1
- QFOHBWFCKVYLES-UHFFFAOYSA-N Butylparaben Chemical compound CCCCOC(=O)C1=CC=C(O)C=C1 QFOHBWFCKVYLES-UHFFFAOYSA-N 0.000 description 1
- 229940084030 CARBOXYMETHYLCELLULOSE CALCIUM Drugs 0.000 description 1
- SWBRTXAKRKRGPH-STWYSWDKSA-N CC=CC=CC(O)=O.C\C=C\C=C\C(O)=O Chemical compound CC=CC=CC(O)=O.C\C=C\C=C\C(O)=O SWBRTXAKRKRGPH-STWYSWDKSA-N 0.000 description 1
- 229960000800 CETRIMONIUM BROMIDE Drugs 0.000 description 1
- 229960002788 CETRIMONIUM CHLORIDE Drugs 0.000 description 1
- AXCZMVOFGPJBDE-UHFFFAOYSA-L Calcium hydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 1
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 description 1
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 description 1
- 235000002566 Capsicum Nutrition 0.000 description 1
- 235000009467 Carica papaya Nutrition 0.000 description 1
- 240000006432 Carica papaya Species 0.000 description 1
- 235000003301 Ceiba pentandra Nutrition 0.000 description 1
- 240000008159 Ceiba pentandra Species 0.000 description 1
- SXPWTBGAZSPLHA-UHFFFAOYSA-M Cetalkonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 SXPWTBGAZSPLHA-UHFFFAOYSA-M 0.000 description 1
- 229950009789 Cetomacrogol 1000 Drugs 0.000 description 1
- WOWHHFRSBJGXCM-UHFFFAOYSA-M Cetrimonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+](C)(C)C WOWHHFRSBJGXCM-UHFFFAOYSA-M 0.000 description 1
- BXWNKGSJHAJOGX-UHFFFAOYSA-N Cetyl alcohol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 1
- 229920002101 Chitin Polymers 0.000 description 1
- DJHJJVWPFGHIPH-OODMECLYSA-N Chitin Chemical compound O[C@@H]1C(NC(=O)C)[C@H](O)OC(CO)[C@H]1COC[C@H]1C(NC(C)=O)[C@@H](O)[C@H](COC[C@H]2C([C@@H](O)[C@H](O)C(CO)O2)NC(C)=O)C(CO)O1 DJHJJVWPFGHIPH-OODMECLYSA-N 0.000 description 1
- 229960003260 Chlorhexidine Drugs 0.000 description 1
- 229960002152 Chlorhexidine Acetate Drugs 0.000 description 1
- 229960004504 Chlorhexidine Hydrochloride Drugs 0.000 description 1
- VXIVSQZSERGHQP-UHFFFAOYSA-N Chloroacetamide Chemical compound NC(=O)CCl VXIVSQZSERGHQP-UHFFFAOYSA-N 0.000 description 1
- OSASVXMJTNOKOY-UHFFFAOYSA-N Chlorobutanol Chemical compound CC(C)(O)C(Cl)(Cl)Cl OSASVXMJTNOKOY-UHFFFAOYSA-N 0.000 description 1
- 229960004926 Chlorobutanol Drugs 0.000 description 1
- OSDLLIBGSJNGJE-UHFFFAOYSA-N Chloroxylenol Chemical compound CC1=CC(O)=CC(C)=C1Cl OSDLLIBGSJNGJE-UHFFFAOYSA-N 0.000 description 1
- 241000207199 Citrus Species 0.000 description 1
- ACTIUHUUMQJHFO-UPTCCGCDSA-N Coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 241000222237 Colletotrichum trifolii Species 0.000 description 1
- 229920000858 Cyclodextrin Polymers 0.000 description 1
- XCIXKGXIYUWCLL-UHFFFAOYSA-N Cyclopentanol Chemical compound OC1CCCC1 XCIXKGXIYUWCLL-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N D-Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- FBPFZTCFMRRESA-KAZBKCHUSA-N D-Mannitol Natural products OC[C@@H](O)[C@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KAZBKCHUSA-N 0.000 description 1
- FXHOOIRPVKKKFG-UHFFFAOYSA-N DMA Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 description 1
- WSDISUOETYTPRL-UHFFFAOYSA-N DMDM hydantoin Chemical compound CC1(C)N(CO)C(=O)N(CO)C1=O WSDISUOETYTPRL-UHFFFAOYSA-N 0.000 description 1
- 229920000727 Decyl polyglucose Polymers 0.000 description 1
- 229920002085 Dialdehyde starch Polymers 0.000 description 1
- 239000005696 Diammonium phosphate Substances 0.000 description 1
- SOROIESOUPGGFO-UHFFFAOYSA-N Diazolidinyl urea Chemical compound OCNC(=O)N(CO)C1N(CO)C(=O)N(CO)C1=O SOROIESOUPGGFO-UHFFFAOYSA-N 0.000 description 1
- RUPBZQFQVRMKDG-UHFFFAOYSA-M Didecyldimethylammonium chloride Chemical compound [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC RUPBZQFQVRMKDG-UHFFFAOYSA-M 0.000 description 1
- GHKOFFNLGXMVNJ-UHFFFAOYSA-N Dilauryl thiodipropionate Chemical compound CCCCCCCCCCCCOC(=O)CCSCCC(=O)OCCCCCCCCCCCC GHKOFFNLGXMVNJ-UHFFFAOYSA-N 0.000 description 1
- 239000003508 Dilauryl thiodipropionate Substances 0.000 description 1
- NIQCNGHVCWTJSM-UHFFFAOYSA-N Dimethyl phthalate Chemical compound COC(=O)C1=CC=CC=C1C(=O)OC NIQCNGHVCWTJSM-UHFFFAOYSA-N 0.000 description 1
- REZZEXDLIUJMMS-UHFFFAOYSA-M Dimethyldioctadecylammonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC REZZEXDLIUJMMS-UHFFFAOYSA-M 0.000 description 1
- ZPWVASYFFYYZEW-UHFFFAOYSA-L Dipotassium phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 description 1
- POLCUAVZOMRGSN-UHFFFAOYSA-N Dipropyl ether Chemical group CCCOCCC POLCUAVZOMRGSN-UHFFFAOYSA-N 0.000 description 1
- 229940047642 Disodium Cocoamphodiacetate Drugs 0.000 description 1
- PWWSSIYVTQUJQQ-UHFFFAOYSA-N Distearyl thiodipropionate Chemical compound CCCCCCCCCCCCCCCCCCOC(=O)CCSCCC(=O)OCCCCCCCCCCCCCCCCCC PWWSSIYVTQUJQQ-UHFFFAOYSA-N 0.000 description 1
- 239000002656 Distearyl thiodipropionate Substances 0.000 description 1
- 229940018602 Docusate Drugs 0.000 description 1
- RPWFJAMTCNSJKK-UHFFFAOYSA-N Dodecyl gallate Chemical compound CCCCCCCCCCCCOC(=O)C1=CC(O)=C(O)C(O)=C1 RPWFJAMTCNSJKK-UHFFFAOYSA-N 0.000 description 1
- OJIYIVCMRYCWSE-UHFFFAOYSA-M Domiphen bromide Chemical compound [Br-].CCCCCCCCCCCC[N+](C)(C)CCOC1=CC=CC=C1 OJIYIVCMRYCWSE-UHFFFAOYSA-M 0.000 description 1
- 229960001859 Domiphen bromide Drugs 0.000 description 1
- 239000001856 Ethyl cellulose Substances 0.000 description 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 description 1
- QQZWEECEMNQSTG-UHFFFAOYSA-N Ethyl nitrite Chemical compound CCON=O QQZWEECEMNQSTG-UHFFFAOYSA-N 0.000 description 1
- NUVBSKCKDOMJSU-UHFFFAOYSA-N Ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 description 1
- 240000002989 Euphorbia neriifolia Species 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- 229960002598 Fumaric acid Drugs 0.000 description 1
- 229950002499 Fytic acid Drugs 0.000 description 1
- 239000005980 Gibberellic acid Substances 0.000 description 1
- 108010068370 Glutens Proteins 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 240000007842 Glycine max Species 0.000 description 1
- 229920002527 Glycogen Polymers 0.000 description 1
- 229940096919 Glycogen Drugs 0.000 description 1
- BYSGBSNPRWKUQH-UJDJLXLFSA-N Glycogen Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@@H](O)[C@@H](O[C@@H]2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)O1 BYSGBSNPRWKUQH-UJDJLXLFSA-N 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 229920002907 Guar gum Polymers 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N HCl Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- 240000006669 Helianthus annuus Species 0.000 description 1
- 235000003222 Helianthus annuus Nutrition 0.000 description 1
- 229920002488 Hemicellulose Polymers 0.000 description 1
- DCAYPVUWAIABOU-UHFFFAOYSA-N Hexadecane Chemical compound CCCCCCCCCCCCCCCC DCAYPVUWAIABOU-UHFFFAOYSA-N 0.000 description 1
- VKYKSIONXSXAKP-UHFFFAOYSA-N Hexamethylenetetramine Chemical compound C1N(C2)CN3CN1CN2C3 VKYKSIONXSXAKP-UHFFFAOYSA-N 0.000 description 1
- OQLKNTOKMBVBKV-UHFFFAOYSA-N Hexamidine Chemical compound C1=CC(C(=N)N)=CC=C1OCCCCCCOC1=CC=C(C(N)=N)C=C1 OQLKNTOKMBVBKV-UHFFFAOYSA-N 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
- 229920001479 Hydroxyethyl methyl cellulose Polymers 0.000 description 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 1
- 241000558610 Illicium anisatum Species 0.000 description 1
- IMQLKJBTEOYOSI-GPIVLXJGSA-N Inositol-hexakisphosphate Chemical compound OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O IMQLKJBTEOYOSI-GPIVLXJGSA-N 0.000 description 1
- 239000005909 Kieselgur Substances 0.000 description 1
- QAQJMLQRFWZOBN-LAUBAEHRSA-N L-ascorbyl-6-palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O QAQJMLQRFWZOBN-LAUBAEHRSA-N 0.000 description 1
- 239000011786 L-ascorbyl-6-palmitate Substances 0.000 description 1
- FFFHZYDWPBMWHY-VKHMYHEASA-N L-homocysteine Chemical compound OC(=O)[C@@H](N)CCS FFFHZYDWPBMWHY-VKHMYHEASA-N 0.000 description 1
- 229960000448 Lactic acid Drugs 0.000 description 1
- GUBGYTABKSRVRQ-UUNJERMWSA-N Lactose Natural products O([C@@H]1[C@H](O)[C@H](O)[C@H](O)O[C@@H]1CO)[C@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@H](CO)O1 GUBGYTABKSRVRQ-UUNJERMWSA-N 0.000 description 1
- 229920002011 Lauryl methyl gluceth-10 hydroxypropyl dimonium chloride Polymers 0.000 description 1
- SYELZBGXAIXKHU-UHFFFAOYSA-N Lauryldimethylamine oxide Chemical compound CCCCCCCCCCCC[N+](C)(C)[O-] SYELZBGXAIXKHU-UHFFFAOYSA-N 0.000 description 1
- 229940067606 Lecithin Drugs 0.000 description 1
- 235000019738 Limestone Nutrition 0.000 description 1
- 102000004895 Lipoproteins Human genes 0.000 description 1
- 108090001030 Lipoproteins Proteins 0.000 description 1
- 229920000161 Locust bean gum Polymers 0.000 description 1
- 239000005913 Maltodextrin Substances 0.000 description 1
- 229920002774 Maltodextrin Polymers 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 229960003951 Masoprocol Drugs 0.000 description 1
- 241000539716 Mea Species 0.000 description 1
- 229960004011 Methenamine Drugs 0.000 description 1
- XJRBAMWJDBPFIM-UHFFFAOYSA-N Methyl vinyl ether Chemical compound COC=C XJRBAMWJDBPFIM-UHFFFAOYSA-N 0.000 description 1
- DHVLDKHFGIVEIP-UHFFFAOYSA-N Methyldibromo glutaronitrile Chemical compound BrCC(Br)(C#N)CCC#N DHVLDKHFGIVEIP-UHFFFAOYSA-N 0.000 description 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 1
- 229920000881 Modified starch Polymers 0.000 description 1
- 239000004368 Modified starch Substances 0.000 description 1
- GNSKLFRGEWLPPA-UHFFFAOYSA-M Monopotassium phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 1
- TUFJPPAQOXUHRI-KTKRTIGZSA-N N'-[(Z)-octadec-9-enyl]propane-1,3-diamine Chemical compound CCCCCCCC\C=C/CCCCCCCCNCCCN TUFJPPAQOXUHRI-KTKRTIGZSA-N 0.000 description 1
- CGVLVOOFCGWBCS-RGDJUOJXSA-N N-Octyl β-D-thioglucopyranoside Chemical compound CCCCCCCCS[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O CGVLVOOFCGWBCS-RGDJUOJXSA-N 0.000 description 1
- 125000003047 N-acetyl group Chemical group 0.000 description 1
- 241000244206 Nematoda Species 0.000 description 1
- 241000772415 Neovison vison Species 0.000 description 1
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 1
- 240000008962 Nicotiana tabacum Species 0.000 description 1
- FBWNMEQMRUMQSO-UHFFFAOYSA-N Nonoxynol-9 Chemical compound CCCCCCCCCC1=CC=C(OCCOCCOCCOCCOCCOCCOCCOCCOCCO)C=C1 FBWNMEQMRUMQSO-UHFFFAOYSA-N 0.000 description 1
- 229940087419 Nonoxynol-9 Drugs 0.000 description 1
- SNQQPOLDUKLAAF-UHFFFAOYSA-N Nonylphenol Chemical compound CCCCCCCCCC1=CC=CC=C1O SNQQPOLDUKLAAF-UHFFFAOYSA-N 0.000 description 1
- ZWLPBLYKEWSWPD-UHFFFAOYSA-N O-Toluic acid Chemical compound CC1=CC=CC=C1C(O)=O ZWLPBLYKEWSWPD-UHFFFAOYSA-N 0.000 description 1
- YYELLDKEOUKVIQ-UHFFFAOYSA-N Octaethylene glycol monododecyl ether Chemical compound CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCO YYELLDKEOUKVIQ-UHFFFAOYSA-N 0.000 description 1
- TVMXDCGIABBOFY-UHFFFAOYSA-N Octane Chemical compound CCCCCCCC TVMXDCGIABBOFY-UHFFFAOYSA-N 0.000 description 1
- SMGTYJPMKXNQFY-UHFFFAOYSA-N Octenidine dihydrochloride Chemical compound Cl.Cl.C1=CC(=NCCCCCCCC)C=CN1CCCCCCCCCCN1C=CC(=NCCCCCCCC)C=C1 SMGTYJPMKXNQFY-UHFFFAOYSA-N 0.000 description 1
- FMJSMJQBSVNSBF-UHFFFAOYSA-N Octocrylene Chemical compound C=1C=CC=CC=1C(=C(C#N)C(=O)OCC(CC)CCCC)C1=CC=CC=C1 FMJSMJQBSVNSBF-UHFFFAOYSA-N 0.000 description 1
- ZVVSSOQAYNYNPP-UHFFFAOYSA-N Olaflur Chemical compound F.F.CCCCCCCCCCCCCCCCCCN(CCO)CCCN(CCO)CCO ZVVSSOQAYNYNPP-UHFFFAOYSA-N 0.000 description 1
- ALSTYHKOOCGGFT-KTKRTIGZSA-N Oleyl alcohol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 description 1
- 241000118205 Ovicides Species 0.000 description 1
- 229940116315 Oxalic Acid Drugs 0.000 description 1
- XAPRFLSJBSXESP-UHFFFAOYSA-N Oxycinchophen Chemical compound N=1C2=CC=CC=C2C(C(=O)O)=C(O)C=1C1=CC=CC=C1 XAPRFLSJBSXESP-UHFFFAOYSA-N 0.000 description 1
- CFKMVGJGLGKFKI-UHFFFAOYSA-N P-Chlorocresol Chemical compound CC1=CC(O)=CC=C1Cl CFKMVGJGLGKFKI-UHFFFAOYSA-N 0.000 description 1
- 229940116985 POTASSIUM LAURYL SULFATE Drugs 0.000 description 1
- 229940098424 POTASSIUM PYROPHOSPHATE Drugs 0.000 description 1
- 239000005985 Paclobutrazol Substances 0.000 description 1
- RMOGWMIKYWRTKW-UONOGXRCSA-N Paclobutrazol Chemical compound C([C@@H]([C@@H](O)C(C)(C)C)N1N=CN=C1)C1=CC=C(Cl)C=C1 RMOGWMIKYWRTKW-UONOGXRCSA-N 0.000 description 1
- NJEOXMPQOCEVAI-FTBISJDPSA-M Pahutoxin Chemical compound [Cl-].CCCCCCCCCCCCC[C@H](OC(C)=O)CC(=O)OCC[N+](C)(C)C NJEOXMPQOCEVAI-FTBISJDPSA-M 0.000 description 1
- 235000019482 Palm oil Nutrition 0.000 description 1
- 235000019483 Peanut oil Nutrition 0.000 description 1
- LAPRIVJANDLWOK-UHFFFAOYSA-N Pentaethylene glycol monododecyl ether Chemical compound CCCCCCCCCCCCOCCOCCOCCOCCOCCO LAPRIVJANDLWOK-UHFFFAOYSA-N 0.000 description 1
- 239000006002 Pepper Substances 0.000 description 1
- JGTNAGYHADQMCM-UHFFFAOYSA-N Perfluorobutanesulfonic acid Chemical compound OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F JGTNAGYHADQMCM-UHFFFAOYSA-N 0.000 description 1
- UZUFPBIDKMEQEQ-UHFFFAOYSA-N Perfluorononanoic acid Chemical compound OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F UZUFPBIDKMEQEQ-UHFFFAOYSA-N 0.000 description 1
- YFSUTJLHUFNCNZ-UHFFFAOYSA-N Perfluorooctanesulfonic acid Chemical compound OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F YFSUTJLHUFNCNZ-UHFFFAOYSA-N 0.000 description 1
- SNGREZUHAYWORS-UHFFFAOYSA-N Perfluorooctanoic acid Chemical compound OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F SNGREZUHAYWORS-UHFFFAOYSA-N 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Natural products OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- QCDWFXQBSFUVSP-UHFFFAOYSA-N Phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 1
- 229960005323 Phenoxyethanol Drugs 0.000 description 1
- ZQBAKBUEJOMQEX-UHFFFAOYSA-N Phenyl salicylate Chemical compound OC1=CC=CC=C1C(=O)OC1=CC=CC=C1 ZQBAKBUEJOMQEX-UHFFFAOYSA-N 0.000 description 1
- 229960002553 Phenylmercuric nitrate Drugs 0.000 description 1
- XMIIGOLPHOKFCH-UHFFFAOYSA-N Phenylpropanoic acid Chemical compound OC(=O)CCC1=CC=CC=C1 XMIIGOLPHOKFCH-UHFFFAOYSA-N 0.000 description 1
- UNJJBGNPUUVVFQ-ZJUUUORDSA-N Phosphatidylserine Chemical compound CCCC(=O)O[C@H](COC(=O)CC)COP(O)(=O)OC[C@H](N)C(O)=O UNJJBGNPUUVVFQ-ZJUUUORDSA-N 0.000 description 1
- 229940067631 Phospholipids Drugs 0.000 description 1
- 229940068041 Phytic Acid Drugs 0.000 description 1
- 235000016761 Piper aduncum Nutrition 0.000 description 1
- 235000017804 Piper guineense Nutrition 0.000 description 1
- 240000000129 Piper nigrum Species 0.000 description 1
- 235000008184 Piper nigrum Nutrition 0.000 description 1
- BTSZTGGZJQFALU-UHFFFAOYSA-N Piroctone olamine Chemical compound NCCO.CC(C)(C)CC(C)CC1=CC(C)=CC(=O)N1O BTSZTGGZJQFALU-UHFFFAOYSA-N 0.000 description 1
- 229920001363 Polidocanol Polymers 0.000 description 1
- 229960000502 Poloxamer Drugs 0.000 description 1
- 229940044476 Poloxamer 407 Drugs 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 229950008882 Polysorbate Drugs 0.000 description 1
- 229940068977 Polysorbate 20 Drugs 0.000 description 1
- 229940068968 Polysorbate 80 Drugs 0.000 description 1
- 229940068965 Polysorbates Drugs 0.000 description 1
- 229920001328 Polyvinylidene chloride Polymers 0.000 description 1
- 229940103091 Potassium Benzoate Drugs 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M Potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- TYJJADVDDVDEDZ-UHFFFAOYSA-M Potassium bicarbonate Chemical class [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 1
- ONQDVAFWWYYXHM-UHFFFAOYSA-M Potassium lauryl sulfate Chemical compound [K+].CCCCCCCCCCCCOS([O-])(=O)=O ONQDVAFWWYYXHM-UHFFFAOYSA-M 0.000 description 1
- HDSBZMRLPLPFLQ-UHFFFAOYSA-N Propylene glycol alginate Chemical compound OC1C(O)C(OC)OC(C(O)=O)C1OC1C(O)C(O)C(C)C(C(=O)OCC(C)O)O1 HDSBZMRLPLPFLQ-UHFFFAOYSA-N 0.000 description 1
- 239000005869 Pyraclostrobin Substances 0.000 description 1
- XPPKVPWEQAFLFU-UHFFFAOYSA-J Pyrophosphate Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 description 1
- 229940048084 Pyrophosphate Drugs 0.000 description 1
- ARCJQKUWGAZPFX-ZIAGYGMSSA-N R-trans-stilbene oxide Chemical compound C1([C@@H]2[C@H](O2)C=2C=CC=CC=2)=CC=CC=C1 ARCJQKUWGAZPFX-ZIAGYGMSSA-N 0.000 description 1
- 229940100486 RICE STARCH Drugs 0.000 description 1
- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N Raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 description 1
- MUPFEKGTMRGPLJ-RMMQSMQOSA-N Raffinose Natural products O(C[C@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O[C@@]2(CO)[C@H](O)[C@@H](O)[C@@H](CO)O2)O1)[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 MUPFEKGTMRGPLJ-RMMQSMQOSA-N 0.000 description 1
- 235000019484 Rapeseed oil Nutrition 0.000 description 1
- 241001361634 Rhizoctonia Species 0.000 description 1
- 241000813090 Rhizoctonia solani Species 0.000 description 1
- 235000019774 Rice Bran oil Nutrition 0.000 description 1
- 241001638069 Rigidoporus microporus Species 0.000 description 1
- 229940081967 Rutin Drugs 0.000 description 1
- 229940045905 SODIUM TALLOWATE Drugs 0.000 description 1
- 229940100515 SORBITAN Drugs 0.000 description 1
- 229940057981 STEARALKONIUM CHLORIDE Drugs 0.000 description 1
- 241000221696 Sclerotinia sclerotiorum Species 0.000 description 1
- 241001558929 Sclerotium <basidiomycota> Species 0.000 description 1
- RJFAYQIBOAGBLC-BYPYZUCNSA-N Selenium-L-methionine Chemical compound C[Se]CC[C@H](N)C(O)=O RJFAYQIBOAGBLC-BYPYZUCNSA-N 0.000 description 1
- 229960002718 Selenomethionine Drugs 0.000 description 1
- 239000004113 Sepiolite Substances 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N Silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 229960003885 Sodium Benzoate Drugs 0.000 description 1
- 229940083575 Sodium Dodecyl Sulfate Drugs 0.000 description 1
- 239000004115 Sodium Silicate Substances 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M Sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- WTCBONOLBHEDIL-UHFFFAOYSA-M Sodium iodate Chemical compound [Na+].[O-]I(=O)=O WTCBONOLBHEDIL-UHFFFAOYSA-M 0.000 description 1
- BTURAGWYSMTVOW-UHFFFAOYSA-M Sodium laurate Chemical compound [Na+].CCCCCCCCCCCC([O-])=O BTURAGWYSMTVOW-UHFFFAOYSA-M 0.000 description 1
- 229940082004 Sodium laurate Drugs 0.000 description 1
- KSAVQLQVUXSOCR-UHFFFAOYSA-M Sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- MDSQKJDNWUMBQQ-UHFFFAOYSA-M Sodium myreth sulfate Chemical compound [Na+].CCCCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O MDSQKJDNWUMBQQ-UHFFFAOYSA-M 0.000 description 1
- QSKQNALVHFTOQX-UHFFFAOYSA-M Sodium nonanoyloxybenzenesulfonate Chemical compound [Na+].CCCCCCCCC(=O)OC1=CC=CC=C1S([O-])(=O)=O QSKQNALVHFTOQX-UHFFFAOYSA-M 0.000 description 1
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M Sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 description 1
- NTHWMYGWWRZVTN-UHFFFAOYSA-N Sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 description 1
- 229940091252 Sodium supplements Drugs 0.000 description 1
- HVUMOYIDDBPOLL-XWVZOOPGSA-N Sorbitan monostearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O HVUMOYIDDBPOLL-XWVZOOPGSA-N 0.000 description 1
- IJCWFDPJFXGQBN-BIFNRIDTSA-N Sorbitan tristearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCC)[C@H]1OC[C@@H](O)[C@@H]1OC(=O)CCCCCCCCCCCCCCCCC IJCWFDPJFXGQBN-BIFNRIDTSA-N 0.000 description 1
- UQZIYBXSHAGNOE-XNSRJBNMSA-N Stachyose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO[C@@H]3[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O3)O)O2)O)O1 UQZIYBXSHAGNOE-XNSRJBNMSA-N 0.000 description 1
- UQZIYBXSHAGNOE-USOSMYMVSA-N Stachyose Natural products O(C[C@H]1[C@@H](O)[C@H](O)[C@H](O)[C@@H](O[C@@]2(CO)[C@H](O)[C@@H](O)[C@@H](CO)O2)O1)[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@H](CO[C@@H]2[C@@H](O)[C@@H](O)[C@@H](O)[C@H](CO)O2)O1 UQZIYBXSHAGNOE-USOSMYMVSA-N 0.000 description 1
- GLDOVTGHNKAZLK-UHFFFAOYSA-N Stearyl alcohol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 1
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Natural products C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 1
- NJGWOFRZMQRKHT-WGVNQGGSSA-N Surfactin Chemical compound CC(C)CCCCCCCCC[C@@H]1CC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O1 NJGWOFRZMQRKHT-WGVNQGGSSA-N 0.000 description 1
- 229940051002 THONZONIUM BROMIDE Drugs 0.000 description 1
- FQENQNTWSFEDLI-UHFFFAOYSA-J Tetrasodium pyrophosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 description 1
- 235000009470 Theobroma cacao Nutrition 0.000 description 1
- 240000000280 Theobroma cacao Species 0.000 description 1
- 229940033663 Thimerosal Drugs 0.000 description 1
- ODJQKYXPKWQWNK-UHFFFAOYSA-N Thiodipropionic acid Chemical compound OC(=O)CCSCCC(O)=O ODJQKYXPKWQWNK-UHFFFAOYSA-N 0.000 description 1
- 239000003490 Thiodipropionic acid Substances 0.000 description 1
- CWERGRDVMFNCDR-UHFFFAOYSA-N Thioglycolic acid Chemical compound OC(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-N 0.000 description 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L Thiomersal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
- 229940094937 Thioredoxin Drugs 0.000 description 1
- WBWDWFZTSDZAIG-UHFFFAOYSA-M Thonzonium bromide Chemical compound [Br-].N=1C=CC=NC=1N(CC[N+](C)(C)CCCCCCCCCCCCCCCC)CC1=CC=C(OC)C=C1 WBWDWFZTSDZAIG-UHFFFAOYSA-M 0.000 description 1
- WJCNZQLZVWNLKY-UHFFFAOYSA-N Tiabendazole Chemical compound S1C=NC(C=2NC3=CC=CC=C3N=2)=C1 WJCNZQLZVWNLKY-UHFFFAOYSA-N 0.000 description 1
- 229940116362 Tragacanth Drugs 0.000 description 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N Trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 description 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 description 1
- URAYPUMNDPQOKB-UHFFFAOYSA-N Triacetin Chemical compound CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 description 1
- 229960002622 Triacetin Drugs 0.000 description 1
- REZQBEBOWJAQKS-UHFFFAOYSA-N Triacontanol Chemical compound CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO REZQBEBOWJAQKS-UHFFFAOYSA-N 0.000 description 1
- ICUTUKXCWQYESQ-UHFFFAOYSA-N Triclocarban Chemical compound C1=CC(Cl)=CC=C1NC(=O)NC1=CC=C(Cl)C(Cl)=C1 ICUTUKXCWQYESQ-UHFFFAOYSA-N 0.000 description 1
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 description 1
- ZIBGPFATKBEMQZ-UHFFFAOYSA-N Triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 description 1
- LEHOTFFKMJEONL-UHFFFAOYSA-N Trioxopurine Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
- XZZNDPSIHUTMOC-UHFFFAOYSA-N Triphenyl phosphate Chemical compound C=1C=CC=CC=1OP(OC=1C=CC=CC=1)(=O)OC1=CC=CC=C1 XZZNDPSIHUTMOC-UHFFFAOYSA-N 0.000 description 1
- LWIHDJKSTIGBAC-UHFFFAOYSA-K Tripotassium phosphate Chemical class [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 description 1
- 240000008529 Triticum aestivum Species 0.000 description 1
- HWKQNAWCHQMZHK-UHFFFAOYSA-N Trolnitrate Chemical compound [O-][N+](=O)OCCN(CCO[N+]([O-])=O)CCO[N+]([O-])=O HWKQNAWCHQMZHK-UHFFFAOYSA-N 0.000 description 1
- 229940035936 Ubiquinone Drugs 0.000 description 1
- 229940116269 Uric Acid Drugs 0.000 description 1
- LOIYMIARKYCTBW-OWOJBTEDSA-N Urocanic acid Chemical compound OC(=O)\C=C\C1=CNC=N1 LOIYMIARKYCTBW-OWOJBTEDSA-N 0.000 description 1
- 229940029983 VITAMINS Drugs 0.000 description 1
- 240000006722 Vanilla planifolia Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 229940021016 Vitamin IV solution additives Drugs 0.000 description 1
- 229920004482 WACKER® Polymers 0.000 description 1
- 229920002310 Welan gum Polymers 0.000 description 1
- 229960003487 Xylose Drugs 0.000 description 1
- LWZFANDGMFTDAV-BURFUSLBSA-N [(2R)-2-[(2R,3R,4S)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] dodecanoate Chemical compound CCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O LWZFANDGMFTDAV-BURFUSLBSA-N 0.000 description 1
- PZIVNMZOHNTMKE-UHFFFAOYSA-N [2-(2-hydroxyoctoxy)phenyl]-phenylmethanone Chemical compound CCCCCCC(O)COC1=CC=CC=C1C(=O)C1=CC=CC=C1 PZIVNMZOHNTMKE-UHFFFAOYSA-N 0.000 description 1
- YRXGUZPUZBCGST-UHFFFAOYSA-N [2-(hydroxymethoxy)phenyl]-phenylmethanone Chemical compound OCOC1=CC=CC=C1C(=O)C1=CC=CC=C1 YRXGUZPUZBCGST-UHFFFAOYSA-N 0.000 description 1
- LWZFANDGMFTDAV-IOVMHBDKSA-N [2-[(2R,3S,4R)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] dodecanoate Chemical compound CCCCCCCCCCCC(=O)OCC(O)[C@H]1OC[C@@H](O)[C@@H]1O LWZFANDGMFTDAV-IOVMHBDKSA-N 0.000 description 1
- 239000006096 absorbing agent Substances 0.000 description 1
- 230000000895 acaricidal Effects 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive Effects 0.000 description 1
- 239000001361 adipic acid Substances 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 238000005054 agglomeration Methods 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 239000003619 algicide Substances 0.000 description 1
- 125000002723 alicyclic group Chemical group 0.000 description 1
- 229910000318 alkali metal phosphate Inorganic materials 0.000 description 1
- 150000001447 alkali salts Chemical class 0.000 description 1
- 229910052915 alkaline earth metal silicate Inorganic materials 0.000 description 1
- 125000002877 alkyl aryl group Chemical group 0.000 description 1
- 125000005599 alkyl carboxylate group Chemical group 0.000 description 1
- 125000005907 alkyl ester group Chemical class 0.000 description 1
- 150000008051 alkyl sulfates Chemical class 0.000 description 1
- 150000008052 alkyl sulfonates Chemical class 0.000 description 1
- 235000011399 aloe vera Nutrition 0.000 description 1
- 239000011795 alpha-carotene Substances 0.000 description 1
- 235000003903 alpha-carotene Nutrition 0.000 description 1
- 229910001884 aluminium oxide Inorganic materials 0.000 description 1
- WMGSQTMJHBYJMQ-UHFFFAOYSA-N aluminum;magnesium;silicate Chemical compound [Mg+2].[Al+3].[O-][Si]([O-])([O-])[O-] WMGSQTMJHBYJMQ-UHFFFAOYSA-N 0.000 description 1
- 229910001588 amesite Inorganic materials 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 1
- 229910000387 ammonium dihydrogen phosphate Inorganic materials 0.000 description 1
- 229920005550 ammonium lignosulfonate Polymers 0.000 description 1
- 150000003863 ammonium salts Chemical class 0.000 description 1
- 239000002280 amphoteric surfactant Substances 0.000 description 1
- 230000003444 anaesthetic Effects 0.000 description 1
- 150000008064 anhydrides Chemical class 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 230000001887 anti-feedant Effects 0.000 description 1
- 230000000843 anti-fungal Effects 0.000 description 1
- 229940041158 antibacterial for systemic use Imidazole derivatives Drugs 0.000 description 1
- 239000002519 antifouling agent Substances 0.000 description 1
- 229910052898 antigorite Inorganic materials 0.000 description 1
- 229940042051 antimycotic for systemic use Imidazole derivatives Drugs 0.000 description 1
- 239000003699 antiulcer agent Substances 0.000 description 1
- 239000003443 antiviral agent Substances 0.000 description 1
- 150000001479 arabinose derivatives Chemical class 0.000 description 1
- 239000003849 aromatic solvent Substances 0.000 description 1
- 150000008378 aryl ethers Chemical class 0.000 description 1
- 125000005228 aryl sulfonate group Chemical group 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 235000010385 ascorbyl palmitate Nutrition 0.000 description 1
- 238000003556 assay method Methods 0.000 description 1
- 229960000892 attapulgite Drugs 0.000 description 1
- 229960001799 aurothioglucose Drugs 0.000 description 1
- 239000002363 auxin Substances 0.000 description 1
- NGLMYMJASOJOJY-UHFFFAOYSA-O azanium;calcium;nitrate Chemical compound [NH4+].[Ca].[O-][N+]([O-])=O NGLMYMJASOJOJY-UHFFFAOYSA-O 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 239000003637 basic solution Substances 0.000 description 1
- 229910001570 bauxite Inorganic materials 0.000 description 1
- 125000002511 behenyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000000440 bentonite Substances 0.000 description 1
- 229910000278 bentonite Inorganic materials 0.000 description 1
- 150000001555 benzenes Chemical class 0.000 description 1
- 150000001556 benzimidazoles Chemical class 0.000 description 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-M benzoate Chemical compound [O-]C(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-M 0.000 description 1
- QRUDEWIWKLJBPS-UHFFFAOYSA-N benzotriazole Chemical compound C1=CC=C2N[N][N]C2=C1 QRUDEWIWKLJBPS-UHFFFAOYSA-N 0.000 description 1
- 150000001565 benzotriazoles Chemical class 0.000 description 1
- 229940007550 benzyl acetate Drugs 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 1
- OENHQHLEOONYIE-VYAWBVGESA-N beta-Carotene Natural products CC=1CCCC(C)(C)C=1\C=C\C(\C)=C/C=C/C(/C)=C\C=C\C=C(\C)/C=C/C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-VYAWBVGESA-N 0.000 description 1
- 235000013734 beta-carotene Nutrition 0.000 description 1
- 239000011648 beta-carotene Substances 0.000 description 1
- 229960003237 betaine Drugs 0.000 description 1
- 230000000853 biopesticidal Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229960002836 biphenylol Drugs 0.000 description 1
- CMPOVQUVPYXEBN-UHFFFAOYSA-N bis(2-hydroxyethyl)-methylazanium;chloride Chemical compound Cl.OCCN(C)CCO CMPOVQUVPYXEBN-UHFFFAOYSA-N 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M bisulfite Chemical class OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 description 1
- 229910052796 boron Inorganic materials 0.000 description 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 1
- 235000019437 butane-1,3-diol Nutrition 0.000 description 1
- 235000010354 butylated hydroxytoluene Nutrition 0.000 description 1
- 229940067596 butylparaben Drugs 0.000 description 1
- 235000012970 cakes Nutrition 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000000920 calcium hydroxide Substances 0.000 description 1
- 235000011116 calcium hydroxide Nutrition 0.000 description 1
- 229910001861 calcium hydroxide Inorganic materials 0.000 description 1
- PASHVRUKOFIRIK-UHFFFAOYSA-L calcium sulfate dihydrate Chemical compound O.O.[Ca+2].[O-]S([O-])(=O)=O PASHVRUKOFIRIK-UHFFFAOYSA-L 0.000 description 1
- 239000010495 camellia oil Substances 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 235000013877 carbamide Nutrition 0.000 description 1
- ABDBNWQRPYOPDF-UHFFFAOYSA-M carbonofluoridate Chemical compound [O-]C(F)=O ABDBNWQRPYOPDF-UHFFFAOYSA-M 0.000 description 1
- 150000007942 carboxylates Chemical class 0.000 description 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 description 1
- 235000002354 carica papaya Nutrition 0.000 description 1
- 150000001746 carotenes Chemical class 0.000 description 1
- 235000005473 carotenes Nutrition 0.000 description 1
- 150000001747 carotenoids Chemical class 0.000 description 1
- 229920001525 carrageenan Polymers 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 239000003093 cationic surfactant Substances 0.000 description 1
- 239000004568 cement Substances 0.000 description 1
- 229960000228 cetalkonium chloride Drugs 0.000 description 1
- 229940082500 cetostearyl alcohol Drugs 0.000 description 1
- 229960000541 cetyl alcohol Drugs 0.000 description 1
- 239000003610 charcoal Substances 0.000 description 1
- 230000003559 chemosterilant Effects 0.000 description 1
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 description 1
- 229960003333 chlorhexidine gluconate Drugs 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- MXOAEAUPQDYUQM-UHFFFAOYSA-N chlorphenesin Chemical compound OCC(O)COC1=CC=C(Cl)C=C1 MXOAEAUPQDYUQM-UHFFFAOYSA-N 0.000 description 1
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol group Chemical group [C@@H]1(CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)[C@H](C)CCCC(C)C HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- 239000011651 chromium Substances 0.000 description 1
- 229910052620 chrysotile Inorganic materials 0.000 description 1
- 239000010630 cinnamon oil Substances 0.000 description 1
- 235000020971 citrus fruits Nutrition 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 1
- 229910052803 cobalt Inorganic materials 0.000 description 1
- 239000010941 cobalt Substances 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 235000012716 cod liver oil Nutrition 0.000 description 1
- 239000003026 cod liver oil Substances 0.000 description 1
- 235000017471 coenzyme Q10 Nutrition 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 229960005188 collagen Drugs 0.000 description 1
- 238000005056 compaction Methods 0.000 description 1
- 239000007859 condensation product Substances 0.000 description 1
- LAAPRQODJPXAHC-AATRIKPKSA-N coniferyl benzoate Chemical compound C1=C(O)C(OC)=CC(\C=C\COC(=O)C=2C=CC=CC=2)=C1 LAAPRQODJPXAHC-AATRIKPKSA-N 0.000 description 1
- 230000023298 conjugation with cellular fusion Effects 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
- 239000002385 cottonseed oil Substances 0.000 description 1
- 229910052906 cristobalite Inorganic materials 0.000 description 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 description 1
- 239000001767 crosslinked sodium carboxy methyl cellulose Substances 0.000 description 1
- FHADSMKORVFYOS-UHFFFAOYSA-N cyclooctanol Chemical compound OC1CCCCCCC1 FHADSMKORVFYOS-UHFFFAOYSA-N 0.000 description 1
- DTPCFIHYWYONMD-UHFFFAOYSA-N decaethylene glycol Chemical compound OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO DTPCFIHYWYONMD-UHFFFAOYSA-N 0.000 description 1
- 229940073499 decyl glucoside Drugs 0.000 description 1
- 239000002837 defoliant Substances 0.000 description 1
- 239000003479 dental cement Substances 0.000 description 1
- 239000002781 deodorant agent Substances 0.000 description 1
- 230000000249 desinfective Effects 0.000 description 1
- MNNHAPBLZZVQHP-UHFFFAOYSA-N diammonium hydrogen phosphate Chemical compound [NH4+].[NH4+].OP([O-])([O-])=O MNNHAPBLZZVQHP-UHFFFAOYSA-N 0.000 description 1
- 235000019838 diammonium phosphate Nutrition 0.000 description 1
- 229910000388 diammonium phosphate Inorganic materials 0.000 description 1
- 229960004698 dichlorobenzyl alcohol Drugs 0.000 description 1
- 229910001649 dickite Inorganic materials 0.000 description 1
- UMGXUWVIJIQANV-UHFFFAOYSA-M didecyl(dimethyl)azanium;bromide Chemical compound [Br-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC UMGXUWVIJIQANV-UHFFFAOYSA-M 0.000 description 1
- 229960004670 didecyldimethylammonium chloride Drugs 0.000 description 1
- 235000019304 dilauryl thiodipropionate Nutrition 0.000 description 1
- TUKQLEWOUPCTOS-UHFFFAOYSA-N dimagnesium;dioxido(oxo)silane;hydroxy-oxido-oxosilane;hydrate Chemical compound O.[Mg+2].[Mg+2].O[Si]([O-])=O.O[Si]([O-])=O.[O-][Si]([O-])=O TUKQLEWOUPCTOS-UHFFFAOYSA-N 0.000 description 1
- XTHFKEDIFFGKHM-UHFFFAOYSA-N dimethoxyethane Chemical compound COCCOC XTHFKEDIFFGKHM-UHFFFAOYSA-N 0.000 description 1
- MUXOBHXGJLMRAB-UHFFFAOYSA-N dimethyl butanedioate Chemical compound COC(=O)CCC(=O)OC MUXOBHXGJLMRAB-UHFFFAOYSA-N 0.000 description 1
- LCGLNKUTAGEVQW-UHFFFAOYSA-N dimethyl ether Chemical group COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 description 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 239000004205 dimethyl polysiloxane Substances 0.000 description 1
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 1
- PSLWZOIUBRXAQW-UHFFFAOYSA-M dimethyl(dioctadecyl)azanium;bromide Chemical compound [Br-].CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC PSLWZOIUBRXAQW-UHFFFAOYSA-M 0.000 description 1
- IQDGSYLLQPDQDV-UHFFFAOYSA-N dimethylazanium;chloride Chemical class Cl.CNC IQDGSYLLQPDQDV-UHFFFAOYSA-N 0.000 description 1
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 1
- 235000019329 dioctyl sodium sulphosuccinate Nutrition 0.000 description 1
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 1
- 235000011180 diphosphates Nutrition 0.000 description 1
- 235000019797 dipotassium phosphate Nutrition 0.000 description 1
- 229910000396 dipotassium phosphate Inorganic materials 0.000 description 1
- 150000002016 disaccharides Chemical class 0.000 description 1
- 229910000397 disodium phosphate Inorganic materials 0.000 description 1
- 235000019800 disodium phosphate Nutrition 0.000 description 1
- AEPKFYPUICCNAG-VBXOIZFTSA-L disodium;[2-(3,4-dihydroxyphenyl)-4-oxo-5-sulfonatooxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-7-yl] sulfate Chemical compound [Na+].[Na+].O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(OS([O-])(=O)=O)C=C(OS([O-])(=O)=O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 AEPKFYPUICCNAG-VBXOIZFTSA-L 0.000 description 1
- 235000019305 distearyl thiodipropionate Nutrition 0.000 description 1
- HOWGUJZVBDQJKV-UHFFFAOYSA-N docosane Chemical compound CCCCCCCCCCCCCCCCCCCCCC HOWGUJZVBDQJKV-UHFFFAOYSA-N 0.000 description 1
- GVGUFUZHNYFZLC-UHFFFAOYSA-N dodecyl benzenesulfonate;sodium Chemical compound [Na].CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 GVGUFUZHNYFZLC-UHFFFAOYSA-N 0.000 description 1
- 239000000555 dodecyl gallate Substances 0.000 description 1
- 235000010386 dodecyl gallate Nutrition 0.000 description 1
- 229940080643 dodecyl gallate Drugs 0.000 description 1
- 238000009507 drug disintegration testing Methods 0.000 description 1
- 238000009837 dry grinding Methods 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 235000010350 erythorbic acid Nutrition 0.000 description 1
- 235000019325 ethyl cellulose Nutrition 0.000 description 1
- 229920001249 ethyl cellulose Polymers 0.000 description 1
- SHZIWNPUGXLXDT-UHFFFAOYSA-N ethyl hexanoate Chemical compound CCCCCC(=O)OCC SHZIWNPUGXLXDT-UHFFFAOYSA-N 0.000 description 1
- 229960001617 ethyl hydroxybenzoate Drugs 0.000 description 1
- 235000010228 ethyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000004403 ethyl p-hydroxybenzoate Substances 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- CSRCNKZJIYKJOT-UHFFFAOYSA-N formaldehyde;naphthalene;sodium Chemical compound [Na].O=C.C1=CC=CC2=CC=CC=C21 CSRCNKZJIYKJOT-UHFFFAOYSA-N 0.000 description 1
- 238000005755 formation reaction Methods 0.000 description 1
- 235000019253 formic acid Nutrition 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 150000003045 fructo oligosaccharides Chemical class 0.000 description 1
- 239000002316 fumigant Substances 0.000 description 1
- IXORZMNAPKEEDV-OBDJNFEBSA-N gibberellin A3 Chemical compound C([C@@]1(O)C(=C)C[C@@]2(C1)[C@H]1C(O)=O)C[C@H]2[C@]2(C=C[C@@H]3O)[C@H]1[C@]3(C)C(=O)O2 IXORZMNAPKEEDV-OBDJNFEBSA-N 0.000 description 1
- 239000000174 gluconic acid Substances 0.000 description 1
- 229950006191 gluconic acid Drugs 0.000 description 1
- 235000012208 gluconic acid Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 1
- 235000021312 gluten Nutrition 0.000 description 1
- 125000005456 glyceride group Chemical group 0.000 description 1
- 235000010985 glycerol esters of wood rosin Nutrition 0.000 description 1
- 125000005908 glyceryl ester group Chemical group 0.000 description 1
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 description 1
- 239000001087 glyceryl triacetate Substances 0.000 description 1
- 235000013773 glyceryl triacetate Nutrition 0.000 description 1
- 229920000578 graft polymer Polymers 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 239000003630 growth substance Substances 0.000 description 1
- 235000010417 guar gum Nutrition 0.000 description 1
- 239000000665 guar gum Substances 0.000 description 1
- 229960002154 guar gum Drugs 0.000 description 1
- 229920000591 gum Polymers 0.000 description 1
- 239000003722 gum benzoin Substances 0.000 description 1
- 229940093910 gyncological antiinfectives Imidazole derivatives Drugs 0.000 description 1
- 229910052621 halloysite Inorganic materials 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229910000271 hectorite Inorganic materials 0.000 description 1
- 230000002363 herbicidal Effects 0.000 description 1
- 239000004009 herbicide Substances 0.000 description 1
- 235000010299 hexamethylene tetramine Nutrition 0.000 description 1
- 239000004312 hexamethylene tetramine Substances 0.000 description 1
- TVHALOSDPLTTSR-UHFFFAOYSA-H hexasodium;[oxido-[oxido(phosphonatooxy)phosphoryl]oxyphosphoryl] phosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O TVHALOSDPLTTSR-UHFFFAOYSA-H 0.000 description 1
- 229940051250 hexylene glycol Drugs 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 239000000416 hydrocolloid Substances 0.000 description 1
- 150000004679 hydroxides Chemical class 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 239000001341 hydroxy propyl starch Substances 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 1
- 235000013828 hydroxypropyl starch Nutrition 0.000 description 1
- 229910052900 illite Inorganic materials 0.000 description 1
- 150000002460 imidazoles Chemical class 0.000 description 1
- 150000002462 imidazolines Chemical class 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000002418 insect attractant Substances 0.000 description 1
- 239000000077 insect repellent Substances 0.000 description 1
- 230000000749 insecticidal Effects 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 229940079865 intestinal antiinfectives Imidazole derivatives Drugs 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- KFZMGEQAYNKOFK-UHFFFAOYSA-N iso-propanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 1
- 229940026239 isoascorbic acid Drugs 0.000 description 1
- 229940113096 isoceteth 20 Drugs 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 229910052622 kaolinite Inorganic materials 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 229940094522 laponite Drugs 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 239000006028 limestone Substances 0.000 description 1
- 230000000670 limiting Effects 0.000 description 1
- 239000000944 linseed oil Substances 0.000 description 1
- 235000021388 linseed oil Nutrition 0.000 description 1
- 235000019136 lipoic acid Nutrition 0.000 description 1
- AGBQKNBQESQNJD-UHFFFAOYSA-N lipoic acid Chemical compound OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 229940087748 lithium sulfate Drugs 0.000 description 1
- 229910052899 lizardite Inorganic materials 0.000 description 1
- 235000010420 locust bean gum Nutrition 0.000 description 1
- 239000000711 locust bean gum Substances 0.000 description 1
- 229960004999 lycopene Drugs 0.000 description 1
- 235000012661 lycopene Nutrition 0.000 description 1
- 239000001751 lycopene Substances 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- OAIQHKWDTQYGOK-UHFFFAOYSA-L magnesium;2-[2-(2-dodecoxyethoxy)ethoxy]ethyl sulfate Chemical compound [Mg+2].CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O.CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O OAIQHKWDTQYGOK-UHFFFAOYSA-L 0.000 description 1
- 229940035034 maltodextrin Drugs 0.000 description 1
- PWHULOQIROXLJO-UHFFFAOYSA-N manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 description 1
- 229910052748 manganese Inorganic materials 0.000 description 1
- 239000011572 manganese Substances 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 150000002734 metacrylic acid derivatives Chemical class 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 description 1
- 229920003087 methylethyl cellulose Polymers 0.000 description 1
- 229960002216 methylparaben Drugs 0.000 description 1
- 239000010445 mica Substances 0.000 description 1
- 230000000813 microbial Effects 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 239000004005 microsphere Substances 0.000 description 1
- 239000010446 mirabilite Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000006011 modification reaction Methods 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- 239000003750 molluscacide Substances 0.000 description 1
- 230000002013 molluscicidal Effects 0.000 description 1
- ZOKXTWBITQBERF-UHFFFAOYSA-N molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 description 1
- 229910052750 molybdenum Inorganic materials 0.000 description 1
- 239000011733 molybdenum Substances 0.000 description 1
- 235000019837 monoammonium phosphate Nutrition 0.000 description 1
- 239000006012 monoammonium phosphate Substances 0.000 description 1
- 235000019796 monopotassium phosphate Nutrition 0.000 description 1
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 1
- 150000002772 monosaccharides Chemical class 0.000 description 1
- 229910052627 muscovite Inorganic materials 0.000 description 1
- 125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 150000002790 naphthalenes Chemical class 0.000 description 1
- 229920001206 natural gum Polymers 0.000 description 1
- 239000005645 nematicide Substances 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 150000002823 nitrates Chemical class 0.000 description 1
- PDTFCHSETJBPTR-UHFFFAOYSA-N nitrooxy(phenyl)mercury Chemical compound [O-][N+](=O)O[Hg]C1=CC=CC=C1 PDTFCHSETJBPTR-UHFFFAOYSA-N 0.000 description 1
- VGIBGUSAECPPNB-UHFFFAOYSA-L nonaaluminum;magnesium;tripotassium;1,3-dioxido-2,4,5-trioxa-1,3-disilabicyclo[1.1.1]pentane;iron(2+);oxygen(2-);fluoride;hydroxide Chemical compound [OH-].[O-2].[O-2].[O-2].[O-2].[O-2].[F-].[Mg+2].[Al+3].[Al+3].[Al+3].[Al+3].[Al+3].[Al+3].[Al+3].[Al+3].[Al+3].[K+].[K+].[K+].[Fe+2].O1[Si]2([O-])O[Si]1([O-])O2.O1[Si]2([O-])O[Si]1([O-])O2.O1[Si]2([O-])O[Si]1([O-])O2.O1[Si]2([O-])O[Si]1([O-])O2.O1[Si]2([O-])O[Si]1([O-])O2.O1[Si]2([O-])O[Si]1([O-])O2.O1[Si]2([O-])O[Si]1([O-])O2 VGIBGUSAECPPNB-UHFFFAOYSA-L 0.000 description 1
- 229920000847 nonoxynol Polymers 0.000 description 1
- 229920004918 nonoxynol-9 Polymers 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 239000002777 nucleoside Substances 0.000 description 1
- 125000003835 nucleoside group Chemical group 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- 235000021231 nutrient uptake Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 229960002446 octanoic acid Drugs 0.000 description 1
- 239000000574 octyl gallate Substances 0.000 description 1
- 235000010387 octyl gallate Nutrition 0.000 description 1
- NRPKURNSADTHLJ-UHFFFAOYSA-N octyl gallate Chemical group CCCCCCCCOC(=O)C1=CC(O)=C(O)C(O)=C1 NRPKURNSADTHLJ-UHFFFAOYSA-N 0.000 description 1
- 239000012053 oil suspension Substances 0.000 description 1
- 229960001245 olaflur Drugs 0.000 description 1
- 229940055577 oleyl alcohol Drugs 0.000 description 1
- 125000001117 oleyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Polymers 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 150000001451 organic peroxides Chemical class 0.000 description 1
- 235000010292 orthophenyl phenol Nutrition 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 125000005702 oxyalkylene group Chemical group 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 239000002540 palm oil Substances 0.000 description 1
- 125000001312 palmitoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229910052625 palygorskite Inorganic materials 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 239000010690 paraffinic oil Substances 0.000 description 1
- 229920002866 paraformaldehyde Polymers 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 238000005453 pelletization Methods 0.000 description 1
- 239000000447 pesticide residue Substances 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 229960000969 phenyl salicylate Drugs 0.000 description 1
- PETXWIMJICIQTQ-UHFFFAOYSA-N phenylmethoxymethanol Chemical compound OCOCC1=CC=CC=C1 PETXWIMJICIQTQ-UHFFFAOYSA-N 0.000 description 1
- 239000003016 pheromone Substances 0.000 description 1
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 description 1
- 150000008104 phosphatidylethanolamines Chemical class 0.000 description 1
- XYFCBTPGUUZFHI-UHFFFAOYSA-N phosphine Chemical compound P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 description 1
- 150000003014 phosphoric acid esters Chemical class 0.000 description 1
- 150000003016 phosphoric acids Chemical class 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000000467 phytic acid Substances 0.000 description 1
- 235000002949 phytic acid Nutrition 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 229950001046 piroctone Drugs 0.000 description 1
- 239000005962 plant activator Substances 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- ONJQDTZCDSESIW-UHFFFAOYSA-N polidocanol Chemical compound CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO ONJQDTZCDSESIW-UHFFFAOYSA-N 0.000 description 1
- 229960002226 polidocanol Drugs 0.000 description 1
- 229920001992 poloxamer 407 Polymers 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 description 1
- 229920001467 poly(styrenesulfonates) Polymers 0.000 description 1
- 229920000172 poly(styrenesulfonic acid) Polymers 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 239000004584 polyacrylic acid Substances 0.000 description 1
- 229920002239 polyacrylonitrile Polymers 0.000 description 1
- 229920001521 polyalkylene glycol ether Polymers 0.000 description 1
- 239000011528 polyamide (building material) Substances 0.000 description 1
- 229920000223 polyglycerol Polymers 0.000 description 1
- 235000010958 polyglycerol polyricinoleate Nutrition 0.000 description 1
- 239000003996 polyglycerol polyricinoleate Substances 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229960002796 polystyrene sulfonate Drugs 0.000 description 1
- 239000011970 polystyrene sulfonate Substances 0.000 description 1
- 229940005642 polystyrene sulfonic acid Drugs 0.000 description 1
- 229920000166 polytrimethylene carbonate Polymers 0.000 description 1
- 229920002689 polyvinyl acetate Polymers 0.000 description 1
- 239000011118 polyvinyl acetate Substances 0.000 description 1
- 229940072033 potash Drugs 0.000 description 1
- 229940116905 potassium ascorbyl tocopheryl phosphate Drugs 0.000 description 1
- 235000010235 potassium benzoate Nutrition 0.000 description 1
- 239000004300 potassium benzoate Substances 0.000 description 1
- 235000015497 potassium bicarbonate Nutrition 0.000 description 1
- 239000001184 potassium carbonate Substances 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 229920001592 potato starch Polymers 0.000 description 1
- 230000001737 promoting Effects 0.000 description 1
- 235000010409 propane-1,2-diol alginate Nutrition 0.000 description 1
- 239000000770 propane-1,2-diol alginate Substances 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-M propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- ZTHYODDOHIVTJV-UHFFFAOYSA-N propyl 3,4,5-trihydroxybenzoate Chemical group CCCOC(=O)C1=CC(O)=C(O)C(O)=C1 ZTHYODDOHIVTJV-UHFFFAOYSA-N 0.000 description 1
- 239000000473 propyl gallate Substances 0.000 description 1
- 235000010388 propyl gallate Nutrition 0.000 description 1
- GOOHAUXETOMSMM-UHFFFAOYSA-N propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 description 1
- 229960002662 propylthiouracil Drugs 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 239000008262 pumice Substances 0.000 description 1
- HZRSNVGNWUDEFX-UHFFFAOYSA-N pyraclostrobin Chemical compound COC(=O)N(OC)C1=CC=CC=C1COC1=NN(C=2C=CC(Cl)=CC=2)C=C1 HZRSNVGNWUDEFX-UHFFFAOYSA-N 0.000 description 1
- 229910052903 pyrophyllite Inorganic materials 0.000 description 1
- 229910052904 quartz Inorganic materials 0.000 description 1
- 239000010453 quartz Substances 0.000 description 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 1
- 239000011369 resultant mixture Substances 0.000 description 1
- 239000008165 rice bran oil Substances 0.000 description 1
- 239000003128 rodenticide Substances 0.000 description 1
- 229930002876 rutin Natural products 0.000 description 1
- 235000005493 rutin Nutrition 0.000 description 1
- 229910000275 saponite Inorganic materials 0.000 description 1
- 229910000276 sauconite Inorganic materials 0.000 description 1
- 230000001624 sedative Effects 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 150000003342 selenium Chemical class 0.000 description 1
- 229910052624 sepiolite Inorganic materials 0.000 description 1
- 235000019355 sepiolite Nutrition 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 125000005373 siloxane group Chemical group [SiH2](O*)* 0.000 description 1
- VMHLLURERBWHNL-UHFFFAOYSA-M sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 239000001187 sodium carbonate Substances 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 description 1
- 239000011697 sodium iodate Substances 0.000 description 1
- 235000015281 sodium iodate Nutrition 0.000 description 1
- 229940032753 sodium iodate Drugs 0.000 description 1
- 229940057950 sodium laureth sulfate Drugs 0.000 description 1
- 235000019795 sodium metasilicate Nutrition 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 235000011008 sodium phosphates Nutrition 0.000 description 1
- 229910052911 sodium silicate Inorganic materials 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- CITBNDNUEPMTFC-UHFFFAOYSA-M sodium;2-(hydroxymethylamino)acetate Chemical compound [Na+].OCNCC([O-])=O CITBNDNUEPMTFC-UHFFFAOYSA-M 0.000 description 1
- VQOIVBPFDDLTSX-UHFFFAOYSA-M sodium;3-dodecylbenzenesulfonate Chemical compound [Na+].CCCCCCCCCCCCC1=CC=CC(S([O-])(=O)=O)=C1 VQOIVBPFDDLTSX-UHFFFAOYSA-M 0.000 description 1
- POECFFCNUXZPJT-UHFFFAOYSA-M sodium;carbonic acid;hydrogen carbonate Chemical compound [Na+].OC(O)=O.OC([O-])=O POECFFCNUXZPJT-UHFFFAOYSA-M 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 229940035044 sorbitan monolaurate Drugs 0.000 description 1
- 235000011067 sorbitan monolaureate Nutrition 0.000 description 1
- 235000011076 sorbitan monostearate Nutrition 0.000 description 1
- 239000001587 sorbitan monostearate Substances 0.000 description 1
- 229940035048 sorbitan monostearate Drugs 0.000 description 1
- 235000011078 sorbitan tristearate Nutrition 0.000 description 1
- 239000001589 sorbitan tristearate Substances 0.000 description 1
- 229960004129 sorbitan tristearate Drugs 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 229940012831 stearyl alcohol Drugs 0.000 description 1
- 239000003206 sterilizing agent Substances 0.000 description 1
- ARCJQKUWGAZPFX-UHFFFAOYSA-N stilbene oxide Chemical compound O1C(C=2C=CC=CC=2)C1C1=CC=CC=C1 ARCJQKUWGAZPFX-UHFFFAOYSA-N 0.000 description 1
- 150000001629 stilbenes Chemical class 0.000 description 1
- 235000021286 stilbenes Nutrition 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 235000010965 sucrose esters of fatty acids Nutrition 0.000 description 1
- 239000001959 sucrose esters of fatty acids Substances 0.000 description 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-N sulfonic acid Chemical compound OS(O)=O LSNNMFCWUKXFEE-UHFFFAOYSA-N 0.000 description 1
- 150000003462 sulfoxides Chemical class 0.000 description 1
- 235000020238 sunflower seed Nutrition 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 229920005613 synthetic organic polymer Polymers 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 239000003784 tall oil Substances 0.000 description 1
- RYCLIXPGLDDLTM-UHFFFAOYSA-J tetrapotassium;phosphonato phosphate Chemical compound [K+].[K+].[K+].[K+].[O-]P([O-])(=O)OP([O-])([O-])=O RYCLIXPGLDDLTM-UHFFFAOYSA-J 0.000 description 1
- 235000019818 tetrasodium diphosphate Nutrition 0.000 description 1
- 235000019529 tetraterpenoid Nutrition 0.000 description 1
- 229960002663 thioctic acid Drugs 0.000 description 1
- 235000019303 thiodipropionic acid Nutrition 0.000 description 1
- 229940035024 thioglycerol Drugs 0.000 description 1
- 102000002933 thioredoxin family Human genes 0.000 description 1
- 108060008226 thioredoxin family Proteins 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 229950006144 tonzonium Drugs 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 229920000428 triblock copolymer Polymers 0.000 description 1
- IIYFAKIEWZDVMP-UHFFFAOYSA-N tridecane Chemical compound CCCCCCCCCCCCC IIYFAKIEWZDVMP-UHFFFAOYSA-N 0.000 description 1
- FAGMGMRSURYROS-UHFFFAOYSA-M trihexadecyl(methyl)azanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+](C)(CCCCCCCCCCCCCCCC)CCCCCCCCCCCCCCCC FAGMGMRSURYROS-UHFFFAOYSA-M 0.000 description 1
- IBPRKWGSNXMCOI-UHFFFAOYSA-N trimagnesium;disilicate;hydrate Chemical compound O.[Mg+2].[Mg+2].[Mg+2].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-] IBPRKWGSNXMCOI-UHFFFAOYSA-N 0.000 description 1
- CWBIFDGMOSWLRQ-UHFFFAOYSA-N trimagnesium;hydroxy(trioxido)silane;hydrate Chemical compound O.[Mg+2].[Mg+2].[Mg+2].O[Si]([O-])([O-])[O-].O[Si]([O-])([O-])[O-] CWBIFDGMOSWLRQ-UHFFFAOYSA-N 0.000 description 1
- AISMNBXOJRHCIA-UHFFFAOYSA-N trimethylazanium;bromide Chemical compound Br.CN(C)C AISMNBXOJRHCIA-UHFFFAOYSA-N 0.000 description 1
- 229910000406 trisodium phosphate Inorganic materials 0.000 description 1
- 239000002383 tung oil Substances 0.000 description 1
- 229940040064 ubiquinol Drugs 0.000 description 1
- QNTNKSLOFHEFPK-UPTCCGCDSA-N ubiquinol-10 Chemical compound COC1=C(O)C(C)=C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)C(O)=C1OC QNTNKSLOFHEFPK-UPTCCGCDSA-N 0.000 description 1
- 230000021037 unidirectional conjugation Effects 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 229910052720 vanadium Inorganic materials 0.000 description 1
- LEONUFNNVUYDNQ-UHFFFAOYSA-N vanadium(0) Chemical compound [V] LEONUFNNVUYDNQ-UHFFFAOYSA-N 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 229910052902 vermiculite Inorganic materials 0.000 description 1
- 239000010455 vermiculite Substances 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229930003231 vitamins Natural products 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 238000001238 wet grinding Methods 0.000 description 1
- 239000010698 whale oil Substances 0.000 description 1
- 235000021307 wheat Nutrition 0.000 description 1
- 235000015099 wheat brans Nutrition 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 229920001221 xylan Polymers 0.000 description 1
- 150000004823 xylans Chemical class 0.000 description 1
- YBTQRZBBLJRNOC-UHFFFAOYSA-N zinc;2-methoxy-4-prop-2-enylphenol;oxygen(2-) Chemical compound [O-2].[Zn+2].COC1=CC(CC=C)=CC=C1O YBTQRZBBLJRNOC-UHFFFAOYSA-N 0.000 description 1
- 239000002888 zwitterionic surfactant Substances 0.000 description 1
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N β-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- YEJRWHAVMIAJKC-UHFFFAOYSA-N γ-lactone 4-hydroxy-butyric acid Chemical compound O=C1CCCO1 YEJRWHAVMIAJKC-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01C—PLANTING; SOWING; FERTILISING
- A01C1/00—Apparatus, or methods of use thereof, for testing or treating seed, roots, or the like, prior to sowing or planting
- A01C1/06—Coating or dressing seed
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01G—HORTICULTURE; CULTIVATION OF VEGETABLES, FLOWERS, RICE, FRUIT, VINES, HOPS OR SEAWEED; FORESTRY; WATERING
- A01G7/00—Botany in general
- A01G7/06—Treatment of growing trees or plants, e.g. for preventing decay of wood, for tingeing flowers or wood, for prolonging the life of plants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/12—Powders or granules
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/12—Powders or granules
- A01N25/14—Powders or granules wettable
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
- A01N31/16—Oxygen or sulfur directly attached to an aromatic ring system with two or more oxygen or sulfur atoms directly attached to the same aromatic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/02—Sulfur; Selenium; Tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/16—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/20—Bacteria; Substances produced thereby or obtained therefrom
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/30—Microbial fungi; Substances produced thereby or obtained therefrom
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/03—Algae
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/10—Apiaceae or Umbelliferae [Carrot family], e.g. parsley, caraway, dill, lovage, fennel or snakebed
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/12—Asteraceae or Compositae [Aster or Sunflower family], e.g. daisy, pyrethrum, artichoke, lettuce, sunflower, wormwood or tarragon
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/22—Lamiaceae or Labiatae [Mint family], e.g. thyme, rosemary, skullcap, selfheal, lavender, perilla, pennyroyal, peppermint or spearmint
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/24—Lauraceae [Laurel family], e.g. laurel, avocado, sassafras, cinnamon or camphor
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/28—Myrtaceae [Myrtle family], e.g. teatree or clove
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/40—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/40—Liliopsida [monocotyledons]
- A01N65/48—Zingiberaceae [Ginger family], e.g. ginger or galangal
-
- C—CHEMISTRY; METALLURGY
- C05—FERTILISERS; MANUFACTURE THEREOF
- C05C—NITROGENOUS FERTILISERS
- C05C9/00—Fertilisers containing urea or urea compounds
-
- C—CHEMISTRY; METALLURGY
- C05—FERTILISERS; MANUFACTURE THEREOF
- C05D—INORGANIC FERTILISERS NOT COVERED BY SUBCLASSES C05B, C05C; FERTILISERS PRODUCING CARBON DIOXIDE
- C05D9/00—Other inorganic fertilisers
-
- C—CHEMISTRY; METALLURGY
- C05—FERTILISERS; MANUFACTURE THEREOF
- C05F—ORGANIC FERTILISERS NOT COVERED BY SUBCLASSES C05B, C05C, e.g. FERTILISERS FROM WASTE OR REFUSE
- C05F11/00—Other organic fertilisers
-
- C—CHEMISTRY; METALLURGY
- C05—FERTILISERS; MANUFACTURE THEREOF
- C05F—ORGANIC FERTILISERS NOT COVERED BY SUBCLASSES C05B, C05C, e.g. FERTILISERS FROM WASTE OR REFUSE
- C05F11/00—Other organic fertilisers
- C05F11/08—Organic fertilisers containing added bacterial cultures, mycelia or the like
-
- C—CHEMISTRY; METALLURGY
- C05—FERTILISERS; MANUFACTURE THEREOF
- C05G—MIXTURES OF FERTILISERS COVERED INDIVIDUALLY BY DIFFERENT SUBCLASSES OF CLASS C05; MIXTURES OF ONE OR MORE FERTILISERS WITH MATERIALS NOT HAVING A SPECIFIC FERTILISING ACTIVITY, e.g. PESTICIDES, SOIL-CONDITIONERS, WETTING AGENTS; FERTILISERS CHARACTERISED BY THEIR FORM
- C05G1/00—Mixtures of fertilisers belonging individually to different subclasses of C05
-
- C—CHEMISTRY; METALLURGY
- C05—FERTILISERS; MANUFACTURE THEREOF
- C05G—MIXTURES OF FERTILISERS COVERED INDIVIDUALLY BY DIFFERENT SUBCLASSES OF CLASS C05; MIXTURES OF ONE OR MORE FERTILISERS WITH MATERIALS NOT HAVING A SPECIFIC FERTILISING ACTIVITY, e.g. PESTICIDES, SOIL-CONDITIONERS, WETTING AGENTS; FERTILISERS CHARACTERISED BY THEIR FORM
- C05G3/00—Mixtures of one or more fertilisers with additives not having a specially fertilising activity
- C05G3/50—Surfactants; Emulsifiers
-
- C—CHEMISTRY; METALLURGY
- C05—FERTILISERS; MANUFACTURE THEREOF
- C05G—MIXTURES OF FERTILISERS COVERED INDIVIDUALLY BY DIFFERENT SUBCLASSES OF CLASS C05; MIXTURES OF ONE OR MORE FERTILISERS WITH MATERIALS NOT HAVING A SPECIFIC FERTILISING ACTIVITY, e.g. PESTICIDES, SOIL-CONDITIONERS, WETTING AGENTS; FERTILISERS CHARACTERISED BY THEIR FORM
- C05G3/00—Mixtures of one or more fertilisers with additives not having a specially fertilising activity
- C05G3/60—Biocides or preservatives, e.g. disinfectants, pesticides or herbicides; Pest repellants or attractants
-
- C—CHEMISTRY; METALLURGY
- C05—FERTILISERS; MANUFACTURE THEREOF
- C05G—MIXTURES OF FERTILISERS COVERED INDIVIDUALLY BY DIFFERENT SUBCLASSES OF CLASS C05; MIXTURES OF ONE OR MORE FERTILISERS WITH MATERIALS NOT HAVING A SPECIFIC FERTILISING ACTIVITY, e.g. PESTICIDES, SOIL-CONDITIONERS, WETTING AGENTS; FERTILISERS CHARACTERISED BY THEIR FORM
- C05G3/00—Mixtures of one or more fertilisers with additives not having a specially fertilising activity
- C05G3/70—Mixtures of one or more fertilisers with additives not having a specially fertilising activity for affecting wettability, e.g. drying agents
-
- C—CHEMISTRY; METALLURGY
- C05—FERTILISERS; MANUFACTURE THEREOF
- C05G—MIXTURES OF FERTILISERS COVERED INDIVIDUALLY BY DIFFERENT SUBCLASSES OF CLASS C05; MIXTURES OF ONE OR MORE FERTILISERS WITH MATERIALS NOT HAVING A SPECIFIC FERTILISING ACTIVITY, e.g. PESTICIDES, SOIL-CONDITIONERS, WETTING AGENTS; FERTILISERS CHARACTERISED BY THEIR FORM
- C05G5/00—Fertilisers characterised by their form
- C05G5/20—Liquid fertilisers
- C05G5/27—Dispersions, e.g. suspensions or emulsions
Abstract
The invention relates to an agrochemical composition comprising a complex formed with at least one of elemental zinc or its salt or derivative or mixtures thereof and at least one of eugenol or source containing eugenol; with at least one agrochemically acceptable excipient. The agrochemical composition is in the form of wettable powders, aqueous suspensions, suspoemulsions, emulsion in water, emulsifiable concentrate, suspension concentrates, liquid suspension, aqueous dispersion, water dispersible granules, broadcast granules, water disintegrable granules, seed dressings or emulsions for seed treatment and combinations thereof. Further, the agrochemical composition comprises particles in the size range of 0.1 micron to 50 microns. Furthermore, the invention relates to a process of preparing the agrochemical composition and to a method of treating plants, seeds, crops, plant propagation material, locus, parts thereof or soil with the agrochemical composition. tion is in the form of wettable powders, aqueous suspensions, suspoemulsions, emulsion in water, emulsifiable concentrate, suspension concentrates, liquid suspension, aqueous dispersion, water dispersible granules, broadcast granules, water disintegrable granules, seed dressings or emulsions for seed treatment and combinations thereof. Further, the agrochemical composition comprises particles in the size range of 0.1 micron to 50 microns. Furthermore, the invention relates to a process of preparing the agrochemical composition and to a method of treating plants, seeds, crops, plant propagation material, locus, parts thereof or soil with the agrochemical composition.
Description
Amended Specification
AN AGROCHEMICAL COMPOSITION
1. FIELD OF THE INVENTION
The invention relates to an agrochemical composition comprising a complex
formed with at least one of elemental zinc or its salt or derivative or mixtures thereof
and at least one of eugenol or a source thereof; with at least one agrochemically
acceptable excipient. The agrochemical composition is in the form of wettable
powder, aqueous suspension, suspoemulsion, emulsion in water, emulsifiable
concentrate, suspension concentrate, water dispersible granules, microgranules,
broadcast granules, water disintegrable granules, oil dispersion or suspension, seed
dressings or emulsions for seed treatment, and combinations thereof. Further, the
agrochemical composition comprises the particles in the size range of from 0.1
micron to 50 microns. Furthermore, the invention relates to a process of preparing
the agrochemical composition and to a method of treating plants, seeds, crops, plant
propagation material, locus, parts thereof or soil with the agrochemical
composition.
The agrochemical composition is suitable for protection of plant, enhance plant
growth, increase plant defense, protection of plants from biotic and abiotic stresses.
2. BACKGROUND OF THE INVENTION
In describing the embodiments of the invention, specific terminology is chosen for
the sake of clarity. However, it is not intended that the invention be limited to the
specific terms so selected and it is to be understood that each specific term includes
all technical equivalents that operate in a similar manner to accomplish a similar
purpose.
Amended Specification
Pesticides are commonly used in agriculture for plant protection; however, the use
of synthetic pesticides is a matter of concern for both the environment and
consumers in the agrochemical sector. Further to this, it has been observed that
prolonged use of synthetic pesticides against certain pests and plant diseases results
in development of pest resistance requiring increased dosages of pesticide for
effective results and thus a major concern of pesticide residue in plant produce.
Further, environmental pollution, impact on biodiversity and operational cost have
created the need for developing an alternative solution which is environmentally
safer and provides a residue free plant protection. It was noticed that plant derived
materials are an excellent alternative to synthetic pesticides so as to reduce
environmental concerns and assure safety to consumers.
The inventors of the present invention found that the agrochemical composition
comprising a complex formed with one of elemental zinc or its salt or derivative
thereof and at least one of eugenol or a source thereof; with at least one
agrochemical excipient, provides an effective control against various pests, diseases
and demonstrate excellent field efficacy in terms of improved yield of crop, plant
physiological parameters such as increased rooting, improved foliage, disease
resistance, increased greenness of the crops thus providing a nutritionally rich crop.
The composition of the present invention can be applied as a foliar spray or to the
soil, seed treatment, seed painting, through broadcasting or through drip or trickle
irrigation.
It was noted by the present inventors that the composition of the present invention
is not only highly effective for plant protection but also has no negative impact of
particular residues generally formed by the application of synthetic pesticides.
Zinc oxide eugenol is commonly used in the field of orthodentistry as dental cement
filling material because of its anesthetic and antibacterial properties. These cements
are also known to have other applications like providing sedative effect in deep
preparations, as antimicrobial additive in paint etc.
Amended Specification
WO/0049996 discloses use of zinc oxide coated microspheres with eugenol as a
deodorant composition. EP58091972 discloses the use of eugenol or isoeugenol
zinc salt as an antiulcer agent.
However, there is no such disclosure or teaching in the art of a complex being
formed with eugenol or its source with elemental zinc, its salts, derivative thereof
and the complex being formulated for agrochemical use namely as a water
dispersible or water disintegrable granules or suspension concentrates or
suspoemulsion etc., with specific granule and particle sizes leading to effective
control against various pests, diseases and improvement in crop yield.
3. SUMMARY OF THE INVENTION:
The inventors have determined that an agrochemical composition comprising a
complex wherein the complex formed with at least one of elemental zinc or its salt
or derivative or mixtures thereof and at least one of eugenol or a source thereof;
with at least one agrochemical excipient demonstrated excellent control over pests
and various plant pathogens infecting crops and exhibits enhanced stability even at
extended storage under higher temperatures.
Further, the agrochemical composition is in the form of solid or liquid or gel and
comprises particles in the size range of 0.1 micron to 50 microns.
Furthermore, the invention relates to a process of preparing the agrochemical
composition comprising a complex formed by at least one of elemental zinc or its
salt or derivative or mixtures thereof and at least one of eugenol or a source thereof.
The invention further relates to a method of protecting the crop, improving the crop
health and growth, enhancing crop yield, strengthening the plant, increasing crop
Amended Specification
defense, protecting the crops from biotic and abiotic stresses or conditioning the
soil; the method comprises treating at least one of seeds, seedling, crops, a plant,
plant propagation material, locus, parts thereof or to the surrounding soil with
effective amount of the agrochemical composition which includes a complex
formed with at least one of elemental zinc or its salt or derivative thereof and at
least one of eugenol or a source thereof; with at least one agrochemical excipient.
It was further observed that the agrochemical composition of the present invention
exhibits superior physical characteristics such as suspensibility, dispersibility,
flowability, wettabilty, viscosity, pourability and stability towards heat, light,
temperature, caking etc. The compositions of the present invention also
demonstrated superior performance under accelerated storage conditions.
4. DESCRIPTION OF THE INVENTION:
In describing the embodiment of the invention, specific terminology has been
chosen for the sake of clarity. However, it is not intended that the invention be
limited to the specific terms so selected and it is to be understood that such specific
terms include all technical equivalents that operate in a similar manner to
accomplish a similar purpose. It is understood that any numerical range recited
herein is intended to include all sub ranges subsumed. Also, unless denoted
otherwise percentage of components in a composition are presented as weight
percent.
According to the invention, the term "complex formed with at least one of elemental
zinc or a salt or a derivative thereof with at least one of eugenol or a source thereof”
encompasses “salt” or chelate” of the same.
Amended Specification
A water dispersible granule is defined as a formulation which disperses or dissolves
rapidly when added to water to give a fine particle suspension. As described herein,
“WG” or “WDG” refer to water dispersible granules.
According to the invention, the term liquid suspension encompasses “aqueous
suspension” or aqueous dispersion” or “suspension concentrates (SC)” or
“suspoemulsion (SE)” composition. Liquid suspension can be defined as
composition wherein solid particles are dispersed or suspended in a liquid. The
liquid as a vehicle can be water and/or a water miscible solvent.
As defined herein, WP refers to a wettable powder, which can be a powder
formulation to be applied as a suspension after dispersion in water.
As defined herein, EC refers to an emulsifiable concentrate, which can be a liquid
homogenous formulation to be applied as an emulsion after dilution in water.
As defined herein, SE refers to a suspoemulsion which is a combination of
suspension concentrate (SC) and concentrated aqueous emulsion (EW)
technologies.
As described herein, ZC refers to a stable suspension of capsules and an active
ingredient in a liquid, normally intended for dilution with water before use.
As defined herein, OD refers to oil dispersion or oil suspension wherein a solid
active ingredient is dispersed in oil. The oil can vary from paraffinic to aromatic
solvent types and vegetable oil or methylated seed oils.
The invention relates to an agrochemical composition comprising a complex
formed with at least one elemental zinc or its salt or derivative thereof and at least
one of eugenol or a source thereof; with at least one agrochemical excipient.
Amended Specification
According to an embodiment, the complex is present in the concentration range of
from 1% to 95% w/w of the total composition. According to further embodiment,
the complex is present in the range of from 5% to 95% w/w of the total composition.
According to further embodiment, the complex is present in the range of from 5%
to 90% w/w of the total composition. According to further embodiment, the
complex is present in the range of from 5% to 85% w/w of the total composition.
According to further embodiment, the complex is present in the range of from 5%
to 80% w/w of the total composition. According to further embodiment, the
complex is present in the range of from 5% to 70% w/w of the total composition.
According to further embodiment, the complex is present in the range of from 5%
to 60% w/w of the total composition. According to further embodiment, the
complex is present in the range of from 5% to 50% w/w of the total composition.
According to an embodiment, the zinc salt or derivative thereof includes one or
more of water soluble and/or water insoluble zinc salts, or derivatives and mixtures
thereof.
According to an embodiment, the zinc salts, derivatives thereof particularly include
water insoluble zinc salts or derivatives and mixtures thereof. According to an
embodiment, the water insoluble zinc salts include one or more of zinc oxide, zinc
carbonate, zinc hydroxides, zinc stearate or derivatives and mixtures thereof.
However, those skilled in the art will appreciate that it is possible to utilize other
water insoluble zinc salts or derivatives without departing from the scope of the
invention.
According to an embodiment, the zinc salts, derivatives thereof particularly include
water soluble zinc salts or derivatives and mixtures thereof. According to an
embodiment, the water soluble salts include one or more of zinc acetate, zinc
chloride, zinc nitrate, zinc sulfate, zinc bromide, sodium zincate, zinc iodide or
derivatives and mixtures thereof. However, those skilled in the art will appreciate
that it is possible to utilize other water soluble zinc salts or derivatives without
departing from the scope of the invention.
Amended Specification
According to an embodiment, the eugenol can be either synthetically prepared or
obtained from natural sources and is commercially available from a wide variety of
suppliers. According to an embodiment, the source of eugenol includes one or more
of essential oil or plant extract or mixtures thereof. According to a further
embodiment, the essential oil or plant extract includes one or more of clove,
nutmeg, cinnamon, basil, bay leaf, ginger, celery, vanilla, lemon balm, dill,
japanese star anise, cinnamomum, wormwood and mixtures thereof. However,
those skilled in the art will appreciate that it is possible to utilize other essential oils
or plant extracts as source of eugenol without departing from the scope of the
invention. The essential oils or plant extracts are commercially manufactured and
easily available through various suppliers in India and abroad. The eugenol
employed for the purposes of preparing the composition of the present invention
has been procured from foreign vendors.
According to an embodiment, the agrochemical composition comprises the
particles in the size range of 0.1 micron to 50 microns, preferably in the size range
of 0.1 micron to 20 microns. The particle size range of 0.1-50 microns of the
agrochemical composition was found to be important not only in terms of ease of
application but also in terms of efficacy.
According to an embodiment, the agrochemical composition is in a solid form or a
liquid form or in gel form. According to an embodiment, the agrochemical
composition may be in the form of wettable powders, aqueous suspensions,
suspoemulsions, suspension concentrates, emulsion in water, oil dispersion, liquid
suspension, water dispersible granules, broadcast granules, water disintegrable
granules, micro granules, seed dressings or emulsions for seed treatment,
emulsifiable concentrate and combinations thereof.
According to an embodiment, the agrochemical composition is in the form of solid.
According to an embodiment, the agrochemical composition is in the form of water
Amended Specification
dispersible granules, broadcast granules, water disintegrable granules,
microgranules and wettable powders.
According to an embodiment, the solid agrochemical composition includes a
complex present in the concentration range of from 1% to 95% w/w of the total
composition. According to an embodiment, the solid agrochemical composition
includes a complex present in the concentration range of from 10% to 95% w/w of
the total composition. According to an embodiment, the solid agrochemical
composition includes a complex present in the concentration range of from 10% to
90% w/w of the total composition. According to an embodiment, the solid
agrochemical composition includes a complex present in the concentration range of
from 10% to 85% w/w of the total composition. According to an embodiment, the
solid agrochemical composition includes a complex present in the concentration
range of from 10% to 80% w/w of the total composition.
According to an embodiment, the solid agrochemical composition comprises
particles in the size range of 0.1 to 50 microns, preferably in the size range of 0.1
to 20 microns.
According to an embodiment, the agrochemical composition is in the form of water
dispersible granules, broadcast granules, water disintegrable granules, wherein the
granules are in the size range of 0.1- 6 mm, preferably in the size range of 0.1-5
mm, preferably in the size range of 0.1-4 mm, preferably in the size range of 0.1-3
mm, preferably in the size range of 0.1-2.5 mm.
According to an embodiment, the agrochemical composition is in the form of micro
granules, wherein the granules are in the size range of 0.1-2.5 mm, preferably in the
size range of 0.1-2 mm, preferably in the size range of 0.1-1.5 mm, preferably in
the size range of 0.1-1 mm, preferably in the size range of 0.1-0.5 mm.
Amended Specification
According to an embodiment, the agrochemical composition is in the form of liquid.
According to an embodiment, the agrochemical composition is in the form of
aqueous suspension, suspoemulsion, suspension concentrate, emulsion in water, oil
dispersion or suspension, liquid suspension, seed dressings or emulsions for seed
treatment, emulsifiable concentrate and combinations thereof.
According to an embodiment, the liquid agrochemical composition includes a
complex present in the concentration range of from 1% to 70% w/w of the total
composition. According to an embodiment, the liquid agrochemical composition
includes a complex present in the concentration range of from 5% to 70% w/w of
the total composition. According to an embodiment, the liquid agrochemical
composition includes a complex present in the concentration range of from 5% to
60% w/w of the total composition. According to an embodiment, the liquid
agrochemical composition includes a complex present in the concentration range of
from 5% to 50% w/w of the total composition.
According to an embodiment, the liquid agrochemical composition comprises
particles in the size range of 0.1 to 50 microns, preferably the liquid agrochemical
composition comprises particles in the size range of 0.1 to 20 microns.
According to an embodiment, the agrochemical composition may optionally
comprise at least one fertilizer. Application of fertilizers not only assists in
increasing yield and promoting healthy crop but also helps in development of
defense against the pest and disease attack.
According to another embodiment, the fertilizers include single nutrient fertilizers,
multi nutrient fertilizers, binary fertilizers, compound fertilizers, organic fertilizers
and mixtures thereof. However, those skilled in the art will appreciate that it is
possible to utilize other fertilizers known in the art without departing from the scope
of the invention.
Amended Specification
According to yet another embodiment, the fertilizer comprises one or more of water
soluble fertilizer or water insoluble fertilizer or salts or complexes or derivatives
and mixtures thereof.
According to further embodiment, the fertilizers include nitrogen, phosphate,
potash, ammonia, ammonium nitrate, urea, sodium nitrate, potassium chloride,
potassium sulfate, potassium carbonate, potassium nitrate, monoammonium
phosphate, diammonium phosphate, calcium ammonium nitrate, super phosphates,
phosphogypsum, triple super phosphates, sulfur fertilizers, NPK fertilizers or salts
or complexes or derivatives and mixtures thereof. However, those skilled in the art
will appreciate that it is possible to use other fertilizers without departing from the
scope of the present invention.
According to an embodiment, the fertilizer is present in the range of 1% to 90%
w/w of the total composition. Preferably, the fertilizer is present in the range of 1%
to 40% w/w of the total composition.
According to an embodiment, the agrochemical composition further optionally
comprises one or more of nutrients, bio stimulants, pesticidal actives, plant growth
regulators, microbes, bacteriospores, algae or salts or complexes or derivatives and
mixtures thereof. According to an embodiment, the nutrients, bio stimulants,
pesticidal actives, plant growth regulators, microbes, bacteriospores, algae or salts
or complexes or derivatives and mixtures may be formulated separately to be
included in the composition of the present invention.
According to another embodiment, the nutrients comprise one or more of
macronutrients, micronutrients, in their elemental form or salts or complexes
derivatives and mixtures thereof.
According to another embodiment, the nutrients comprise one or more of sulfur,
iron, boron, calcium, magnesium, copper, manganese, silicon, cobalt, chlorine,
Amended Specification
sodium, molybdenum, chromium, vanadium, selenium, nickel, iodine, chlorine,
fluorine, phosphorous, potassium, in their elemental form or salts or complexes or
derivatives and mixtures thereof. The composition may further optionally comprise
of other nutrients namely one or more of vitamins, organic acids or salts or
complexes or derivatives and mixtures thereof. However, the above list of nutrients
is exemplary and not meant to limit the scope of the invention.
According to an embodiment, the nutrients are present in the range of from 0.1% to
70% w/w of the total composition. According to an embodiment, the nutrients are
present in the range of from 0.1% to 40% w/w of the total composition.
According to an embodiment, the plant growth promoters include one or more of
humic acid, ascorbic acids, fulvic acid, lactic acid, oxalic acid, phytic acid, fumaric
acid, gibberellic acid, auxins, citric acid, N-acetyl thiazolidine-4 carboxylic acid,
paclobutrazol, triacontanol and mixtures thereof. However, the above list of plant
growth promoter is exemplary and not meant to limit the scope of the invention.
According to an embodiment, the plant growth promoters are present in the range
of from 0.1% to 60% w/w of the total composition. According to an embodiment,
the plant growth promoters are present in the range of from 0.1% to 40% w/w of
the total composition.
According to an embodiment, the pesticidal actives include one or more of an
antifoulant, an insecticide, a fungicide, a herbicide, a nematicide, a pheromone, a
defoliant, an acaricide, a plant growth regulator, an algicide, an antifeedant, an
avicide, a bactericide, a bird repellent, a biopesticide, a biocide, a chemosterilant, a
safener, an insect attractant, an insect repellent, an insect growth regulator, a
mammal repellent, a mating disrupter, a disinfectant, a molluscicide, an
antimicrobial, a miticide, an ovicide, a fumigant, a plant activator, a rodenticide, a
synergist, a virucide, a microbial pesticide, a plant incorporated protectant, other
miscellaneous pesticidal actives or salts or derivatives and mixtures thereof.
Amended Specification
According to an embodiment, pesticide is present in an amount of 0.1% to 80%
w/w of the composition. According to further embodiment, pesticide is present in
an amount of 0.1% to 60% w/w of the composition. According to further
embodiment, pesticide is present in an amount of 0.1% to 40% w/w of the
composition.
According to an embodiment, the agrochemical composition comprises at least one
agrochemically acceptable excipient. According to further embodiment, the
agrochemically acceptable excipient comprises one or more of surfactants,
dispersing agents, emulsifiers, wetting agents, binders or binding agents,
disintegrating agents, fillers or carriers or diluents, spreading agents, coating agents,
buffers or pH adjusters or neutralizing agents, antifoaming agents or defoamers,
penetrants, preservatives, ultraviolet absorbents, UV ray scattering agents,
stabilizers, pigments, colorants, structuring agents, chelating or complexing or
sesquitering sequestering agents, anti-settling agents, thickeners, suspending agents
or suspension aid agents, viscosity modifiers, tackifiers, humectants, rheology
modifiers, sticking agents, anti-freezing agent or freeze point depressants, organic
fluids or oils, solvents including non aqueous solvent, aqueous solvents and
mixtures thereof. However, those skilled in the art will appreciate that it is possible
to utilize additional agrochemically acceptable excipients without departing from
the scope of the present invention.
According to an embodiment, the agrochemical excipients are present in a
concentration range of 1%-95% w/w of the total composition. According to an
embodiment, the agrochemical excipients are present in a concentration range of
1%-90% w/w of the total composition. According to an embodiment, the
agrochemical excipients are present in a concentration range of 1%-80% w/w of the
total composition. According to an embodiment, the agrochemical excipients are
present in a concentration range of 1%-70% w/w of the total composition.
According to an embodiment, the agrochemical excipients are present in a
Amended Specification
concentration range of 1%-60% w/w of the total composition. According to an
embodiment, the agrochemical excipients are present in a concentration range of
1%-50% w/w of the total composition. According to an embodiment, the
agrochemical excipients are present in a concentration range of 1%-40% w/w of the
total composition. According to an embodiment, the agrochemical excipients are
present in a concentration range of 1%-30% w/w of the total composition.
According to an embodiment, the agrochemical excipients are present in a
concentration range of 1%-20% w/w of the total composition. According to an
embodiment, the agrochemical excipients are present in a concentration range of
1%-10% w/w of the total composition.
According to an embodiment, the surfactants which are used in the agrochemical
composition include one or more of anionic, cationic, non-ionic, amphoteric and
polymeric surfactants. According to an embodiment, the surfactants include one or
more of emulsifiers, wetting agents and dispersing agents.
The anionic surfactants include, but not limited to one or more of a salt of fatty acid,
a benzoate, a polycarboxylate, a salt of alkylsulfuric acid ester, alkyl ether sulfates,
an alkyl sulfate, an alkylaryl sulfate, an alkyl diglycol ether sulfate, a salt of alcohol
sulfuric acid ester, an alkyl sulfonate, an alkylaryl sulfonate, an aryl sulfonate, a
lignin sulfonate, an alkyldiphenyletherdisulfonate, a polystyrene sulfonate, a salt of
alkylphosphoric acid ester, an alkylaryl phosphate, a styrylaryl phosphate, sulfonate
docusates, a salt of polyoxyethylene alkyl ether sulfuric acid ester, a
polyoxyethylenealkylaryl ether sulfate, alkyl sarcosinates, alpha olefin sulfonate
sodium salt, alkyl benzene sulfonate or its salts, sodium lauroylsarcosinate,
sulfosuccinates, polyacrylates, polyacrylates – free acid and sodium salt, salt of
polyoxyethylenealkylaryl ether sulfuric acid ester, a polyoxyethylene alkyl ether
phosphate, a salt of polyoxyethylenealkylaryl phosphoric acid ester, sulfosuccinates
-mono and other diesters, phosphate esters, alkyl naphthalene sulfonate-isopropyl
and butyl derivatives, alkyl ether sulfates –sodium and ammonium salts; alkyl aryl
ether phosphates, ethylene oxides and its derivatives, a salt of polyoxyethylene aryl
Amended Specification
ether phosphoric acid ester, mono-alkyl sulphosuccinates, aromatic hydrocarbon
sulphonates, 2-acrylamidomethylpropane sulfonic acid, ammonium lauryl
sulfate, ammonium perfluorononanoate, docusate, disodium cocoamphodiacetate,
magnesium laureth sulfate, perfluorobutanesulfonic acid, perfluorononanoic acid,
carboxylates, perfluorooctanesulfonic acid, perfluorooctanoic acid, phospholipid,
potassium lauryl sulfate, soap, soap substitute, sodium alkyl sulfate, sodium
dodecyl sulfate, sodium dodecylbenzenesulfonate, sodium laurate, sodium laureth
sulfate, sodium lauroylsarcosinate, sodium myreth sulfate, sodium
nonanoyloxybenzenesulfonate, sodium pareth sulfate, alkyl carboxylates, sodium
stearate, alpha olefin sulphonates, naphthalene sulfonate salts, alkyl naphthalene
sulfonate fatty acid salts, naphthalene sulfonate condensates–sodium salt, fluoro
carboxylate, fatty alcohol sulphates, alkyl naphthalene sulfonate condensates–
sodium salt, a naphthalene sulfonic acid condensed with formaldehyde or a salt of
alkylnaphthalene sulfonic acid condensed with formaldehyde; or salts or derivatives
thereof.
Cationic surfactants include, but not limited to one or more of dialkyl dimethyl
ammonium chlorides, alkyl methyl ethoxylated ammonium chlorides or salts,
dodecyl-, coco-, hexadecyl-, octadecyl-, octadecyl/behenyl-, behenyl-,
cocoamidopropyl-,trimethyl ammonium chloride; coco-, stearyl-, bis(2-
hydroxyethyl)methyl ammonium chloride, benzalkonium chloride, alkyl-,
tetradecyl-, octadecyl-dimethyl benzyl ammonium chloride, dioctyl-, di(octyl-
decyl)-, didecyl-, dihexadecyl-distearyl-, di(hydrogenated tallow)-dimethyl
ammonium chloride, di(hydrogenated tallow) benzyl-, trioctyl-, tri(octyl-decyl)-,
tridodecyl-, trihexadecyl-methyl ammonium chloride, dodecyl trimethyl-, dodecyl
dimethyl benzyl-, di-(octyl-decyl) dimethyl, didecyl dimethyl-ammonium bromide,
quaternised amine ethoxylates, behentrimonium chloride, benzalkonium chloride,
benzethonium chloride, benzododecinium bromide, bronidox, quaternary
ammonium salts carbethopendecinium bromide, cetalkonium chloride,
cetrimonium bromide, cetrimonium chloride, cetylpyridinium chloride,
didecyldimethylammonium chloride, dimethyldioctadecylammonium bromide,
Amended Specification
dimethyldioctadecyl ammonium chloride, domiphen bromide, lauryl methyl
gluceth-10 hydroxypropyldimonium chloride, octenidinedihydrochloride, olaflur,
n-oleyl-1, 3-propanediamine, pahutoxin, stearalkonium chloride,
tetramethylammonium hydroxide, thonzonium bromide; salts or derivatives
thereof.
The non-ionic surfactants include, but not limited to one or more of polyol esters,
polyol fatty acid esters, polyethoxylated esters, polyethoxylated alcohols,
ethoxylated and propoxylated fatty alcohols, ethoxylated and propoxylated
alcohols, EO/PO copolymers; EO and PO block copolymers, di, tri-block
copolymers; block copolymers of polyethylene glycol and polypropylene glycol,
poloxamers, polysorbates, alkyl polysaccharides such as alkyl polyglycosides and
blends thereof, amine ethoxylates, sorbitan fatty acid ester, glycol and glycerol
esters, glucosidyl alkyl ethers, sodium tallowate, polyoxyethylene glycol, sorbitan
alkyl esters, sorbitan derivatives, fatty acid esters of sorbitan (Spans) and their
ethoxylated derivatives (Tweens), and sucrose esters of fatty acids, cetostearyl
alcohol, cetyl alcohol, cocamide dea, cocamide mea, decyl glucoside,
decylpolyglucose, glycerol monostearate, lauryl glucoside, maltosides, monolaurin,
narrow-range ethoxylate, nonidet p-40, nonoxynol-9, nonoxynols, octaethylene
glycol monododecyl ether, n-octyl beta-d-thioglucopyranoside, octyl glucoside,
oleyl alcohol, PEG-10 sunflower glycerides, pentaethylene glycol monododecyl
ether, polidocanol, poloxamer, poloxamer 407, polyethoxylated tallow amine,
polyglycerol polyricinoleate, polysorbate, polysorbate 20, polysorbate 80, sorbitan,
sorbitan monolaurate, sorbitanmonostearate, sorbitantristearate, stearyl alcohol,
surfactin, glyceryl laureate, lauryl glucoside, nonylphenolpolyethoxyethanols,
nonyl phenol polyglycol ether, castor oil ethoxylate, polyglycol ethers, polyadducts
of ethylene oxide and propylene oxide, block copolymer of polyalkylene glycol
ether and hydroxystearic acid, tributylphenoxypolyethoxy ethanol,
octylphenoxypolyethoxy ethanol, etho-propoxylatedtristyrlphenols, ethoxylated
alcohols, polyoxy ethylene sorbitan, fatty acid polyglyceride, a fatty acid alcohol
polyglycol ether, acetylene glycol, acetylene alcohol, an oxyalkylene block
Amended Specification
polymer, a polyoxyethylene alkyl ether, a polyoxyethylenealkylaryl ether, a
polyoxyethylenestyrylaryl ether, a polyoxyethylene glycol alkyl ether,
polyethylene glycol, a polyoxyethylene fatty acid ester, a polyoxyethylenesorbitan
fatty acid ester, a polyoxyethylene glycerin fatty acid ester, Alcohol ethoxylates –
C6 to C16/18 alcohols, linear and branched, Alcohol alkoxylates – various
hydrophobes and EO/PO contents and ratios, Fatty acid esters – mono and diesters;
lauric, stearic and oleic; glycerol esters – with and without EO; lauric, stearic, cocoa
and tall oil derived, ethoxylatedglycerine, sorbitan esters – with and without EO;
lauric, stearic and oleic based; mono and trimesters, castor oil ethoxylates – 5 to
200 moles EO; non-hydrogenated and hydrogenated, block polymers, amine
oxides- ethoxylated and non-ethoxylated; alkyl dimethyl, Fatty amine ethoxylates–
coco, tallow, stearyl, oleyl amines, a polyoxyethylene hydrogenated castor oil or a
polyoxypropylene fatty acid ester; salts or derivatives thereof.
Amphoteric or Zwitterionic surfactants include, but not limited one or more of to
betaine, coco and lauryl amidopropyl betaines, coco alkyl dimethyl amine oxides,
alkyl dimethyl betaines; c8 to c18, alkyl dipropionates -sodium
lauriminodipropionate, cocoamidopropylhydroxysulfobetaine, imidazolines,
phospholipids phosphatidylserine, phosphatidylethanolamine,
phosphatidylcholine, and sphingomyelins, lauryl dimethylamine oxide, alkyl
amphoacetates and proprionates, alkyl ampho(di)acetates, and diproprionates,
lecithin and ethanolamine fatty amides; or salts or derivatives thereof.
Surfactants that are commercially available under the trademark but are not limited
to, one or more of Atlas G5000, TERMUL 5429, TERMUL 2510, ECOTERIC®,
EULSOGEN® 118, Genapol®X, Genapol®OX -080, Genapol® C 100,
Emulsogen ® EL 200, Arlacel P135, Hypermer 8261, Hypermer B239, Hypermer
B261, Hypermer B246sf, Solutol HS 15, Promulgen™ D, Soprophor 7961P,
Soprophor TSP/461, Soprophor TSP/724, Croduret 40, Etocas 200, Etocas 29,
Rokacet R26, Cetomacrogol 1000, CHEMONIC OE-20, Triton N-101, Triton X-
100, Tween 20, 40, 60, 65, 80, Span 20, 40, 60, 80, 83, 85, 120, Brij®, Atlox
Amended Specification
4912, Atlas G5000, TERMUL 3512, TERMUL 3015, TERMUL 5429, TERMUL
2510, ECOTERIC®, ECOTERIC® T85, ECOTERIC® T20, TERIC 12A4,
EULSOGEN® 118, Genapol®X, Genapol®OX -080, Genapol® C 100,
Emulsogen ® EL 200, Arlacel P135, Hypermer 8261, Hypermer B239, Hypermer
B261, Hypermer B246sf, Solutol HS 15, Promulgen™ D, Soprophor 7961P,
Soprophor TSP/461, Soprophor TSP/724, Croduret 40, Etocas 200, Etocas 29,
Rokacet R26, CHEMONIC OE-20, Triton™ N-101, IGEPAL CA-630 and
Isoceteth-20. However, those skilled in the art will appreciate that it is possible to
utilize other conventionally known surfactants without departing from the scope of
the present invention.
According to an embodiment, the surfactant is present in an amount of 0.1% to 60%
w/w of the total composition. According to an embodiment, the surfactant is present
in an amount of 0.1% to 40% w/w of the total composition. According to an
embodiment; the surfactant is present in an amount of 0.1% to 30% w/w of the total
composition. According to a further embodiment, the surfactant is present in an
amount of 0.1% to 20% w/w of the total composition. According to an embodiment,
the surfactant is present in an amount of 0.1% to 10% w/w of the total composition.
According to an embodiment, the solvents used in the agrochemical composition
include water miscible solvents. The water miscible solvents include, but not
limited to one or more of 1, 4-dioxane, ethylene glycol, glycerol, n-methyl
pyrrolidone, 1,3-propanediol, 1,5-pentanediol, sorbitol, propylene glycol,
triethylene glycol, 1,2-butanediol, 1,3-butanediol, 1,4-butanediol,
dimethylformamide, dimethoxyethane, dimethyloctanamide, dimethyldecanamide.
However, those skilled in the art will appreciate that it is possible to utilize other
water miscible solvents without departing from the scope of the present invention.
According to an embodiment, the solvent is present in an amount of 0.1-95% w/w
of the total composition. According to an embodiment, the solvent is present in an
amount of 0.1-60% w/w of the total composition. According to an embodiment, the
Amended Specification
solvent is present in an amount of 0.1-40% w/w of the total composition. According
to an embodiment, the solvent is present in an amount of 0.1-30% w/w of the total
composition.
According to an embodiment, the disintegrating agents which are used in the
agrochemical composition include, but not limited to one or more of inorganic
water soluble salts e.g. sodium chloride, nitrate salts; water soluble organic
compounds such as agar, hydroxypropyl starch, carboxymethyl starch ether,
tragacanth, gelatin, casein, microcrystalline cellulose, cross-linked sodium
carboxymethyl cellulose, carboxymethyl cellulose, carboxymethyl cellulose
calcium, sodium tripolyphosphate, sodium hexametaphosphate, metal stearates, a
cellulose powder, dextrin, methacrylate copolymer, Polyplasdone® XL-10
(crosslinked polyvinylpyrrolidone), poly(vinylpyrrolidone), polyaminocarboxylic
acid, sulfonated styrene-isobutylene-maleic anhydride copolymer, salts of
polyacrylates of methacrylates, starch-polyacrylonitrile graft copolymer, sodium or
potassium bicarbonates/ carbonates or their mixtures or salts with acids such as
citric and fumaric acid; or salts or derivatives thereof. However, those skilled in the
art will appreciate that it is possible to utilize different disintegrating agents without
departing from the scope of the present invention.
According to an embodiment, the disintegrating agent is present in an amount of
0.1% to 50% w/w of the composition. According to an embodiment, the
disintegrating agent is present in an amount of 0.1% to 30% w/w of the composition.
According to an embodiment, the disintegrating agent is present in an amount of
0.1% to 20% w/w of the composition. According to an embodiment, the
disintegrating agent is present in an amount of 0.1% to 10% w/w of the composition.
According to an embodiment, the disintegrating agent is present in an amount of
0.1% to 5% w/w of the composition.
According to an embodiment, the binding agents or binders which are used in the
agrochemical composition include, but not limited to one or more of proteins,
Amended Specification
lipoproteins, lipids, glycolipid, glycoprotein, carbohydrates such as
monosaccharides, disaccharides, oligosaccharides and polysaccharides, complex
organic substance, synthetic organic polymers or derivatives and combinations
thereof. However, those skilled in the art will appreciate that it is possible to utilize
different binding agents without departing from the scope of the present invention.
According to an embodiment, the binding agent is present in an amount of 0.1% to
50% w/w of the composition. According to further embodiment, the binding agent
is present in an amount of 0.1% to 30% w/w of the composition. According to
further embodiment, the binding agent is present in an amount of 0.1% to 20% w/w
of the composition. According to further embodiment, the binding agent is present
in an amount of 0.1% to 10% w/w of the composition.
According to an embodiment, the carriers which are used in the agrochemical
composition include, but not limited to one or more of solid carriers or fillers or
diluents. According to another embodiment, the carriers include mineral carriers,
plant carriers, synthetic carriers, water-soluble carriers. However, those skilled in
the art will appreciate that it is possible to utilize different carriers without departing
from the scope of the present invention.
The solid carriers include natural minerals like clay such as china clay, acid clay,
kaolin such as kaolinite, dickite, nacrite, and halloysite, serpentines such as
chrysotile, lizardite, antigorite and amesite, synthetic and diatomaceous silicas,
montmorillonite minerals such as sodium montmorillonite, smectites, such as
saponite, hectorite, sauconite, and hyderite, micas, such as pyrophyllite, talc,
agalmatolite, muscovite, phengite, sericite, and illite, silicas such as cristobalite and
quartz including attapulgite and sepiolite; vermiculite, laponite, pumice, bauxite,
hydrated aluminas, perlite, sodium bicarbonate, volclay, vermiculites, limestone,
natural and synthetic silicates, charcoal, silicas, wet process silicas, dry process
silicas, calcined products of wet process silicas, surface-modified silicas, mica,
zeolite, diatomaceous earth, derivatives thereof; chalks (Omya ®), fuller's earth,
loess, mirabilite, white carbon, slaked lime, synthetic silicic acid, starch, modified
Amended Specification
starch (Pineflow, available from Matsutani Chemical industry Co., Ltd.), cellulose,
plant carriers such as cellulose, chaff, wheat flour, wood flour, starch, rice bran,
wheat bran and soyabean flour, tobacco powder, a vegetable powder polyethylene,
polypropylene, poly(vinylidene chloride), methyl cellulose, hydroxypropyl
cellulose, hydroxypropyl methylcellulose, sodium carboxymethyl cellulose,
propylene glycol alginate, polyvinylpyrrolidone, carboxyvinyl polymer, casein
sodium, sucrose, salt cake, potassium pyrophosphate, sodium tripolyphosphate,
maleic acid, fumaric acid and malic acid or derivatives and mixtures thereof.
Commercially available silicates are Aerosil brands, Sipemat brands as Sipernat ®
50S and CALFLO E, and kaolin 1777. However, those skilled in the art will
appreciate that it is possible to utilize different solid carriers without departing from
the scope of the present invention.
According to an embodiment, the carrier is present in an amount of 0.1% to 98%
w/w of the composition. According to further embodiment, the carrier is present in
an amount of 0.1% to 80% w/w of the composition. According to further
embodiment, the carrier is present in an amount of 0.1% to 60% w/w of the
composition. According to further embodiment, the carrier is present in an amount
of 0.1% to 40% w/w of the composition. According to further embodiment, the
carrier is present in an amount of 0.1% to 20% w/w of the composition.
According to an embodiment, the anti-caking agents which are used in the
agrochemical composition include, but not limited to one or more of
polysaccharides such as starch, alginic acid, mannose, galactose;
poly(vinylpyrrolidone), fumed silica (white carbon), ester gum, a petroleum resin,
Foammaster® Soap L sodium stearate, Brij® 700 polyoxyethylene (100)
stearylether, Aerosol® OT-B sodium dioctyl sulfosuccinate, Silwet® L-77 silicone-
polyether copolymer, sodium acetate, sodium metasilicate, sodium
alkylsulfosuccinates, sodium carbonate or bicarbonate, salts or derivatives thereof.
However, those skilled in the art will appreciate that it is possible to utilize different
anti caking agents without departing from the scope of the present invention.
Amended Specification
According to an embodiment, the anti-caking agent is present in an amount of 0.1%
to 30% w/w of the total composition. According to an embodiment, the anti-caking
agent is present in an amount of 0.1% to 20% w/w of the total composition.
According to an embodiment, the anti-caking agent is present in an amount of 0.1%
to 10% w/w of the total composition. According to an embodiment, the anti-caking
agent is present in an amount of 0.1% to 5% w/w of the total composition.
According to an embodiment, the antifoaming agents or defoamers which are used
in the agrochemical composition include, but not limited to one or more of silica,
siloxane, silicone dioxide, polydimethyl siloxane, alkyl polyacrylates, ethylene
oxide/propylene oxide copolymers, polyethylene glycol, Silicone oils and
magnesium stearate or derivatives thereof. Preferred antifoaming agents include
silicone emulsions (such as, e.g., Silikon® SRE, Wacker or Rhodorsil® from
Rhodia), long-chain alcohols, fatty acids, fluoroorganic compounds. However,
those skilled in the art will appreciate that it is possible to utilize other
conventionally known antifoaming agents without departing from the scope of the
present invention.
According to an embodiment, the anti-foaming agent is present in an amount of
0.01% to 20% w/w of the total composition. According to an embodiment, the anti-
foaming agent is present in an amount of 0.01% to 10% w/w of the total
composition. According to an embodiment, the anti-foaming agent is present in an
amount of 0.01% to 5% w/w of the total composition. According to an embodiment,
the anti-foaming agent is present in an amount of 0.01% to 1% w/w of the total
composition.
According to an embodiment, the pH-adjusters or buffers or neutralizing agents
which are used in the agrochemical composition include both acids and bases of the
organic or inorganic type and mixtures thereof. According to further embodiment,
pH-adjusters or buffers or neutralizing agents include, but not limited to one or more
Amended Specification
of organic acids, inorganic acids and alkali metal compounds or salts or derivatives
thereof. According to an embodiment, the organic acids include, but not limited to
one or more of citric, malic, adipic, fumaric, maleic, succinic, and tartaric acid or
salts or derivatives thereof; and the mono-, di-, or tribasic salts of these acids or
derivatives thereof. Alkali metal compounds include but not limited to, one or more
of hydroxides of alkali metals such as sodium hydroxide and potassium hydroxide,
carbonates of alkali metals such as sodium carbonate, hydrogencarbonates of alkali
metals such as sodium hydrogencarbonate and alkali metal phosphates such as
sodium phosphate and mixtures thereof. According to an embodiment, the salts of
inorganic acids include but not limited to, one or more of alkali metal salts such as
lithium chloride, sodium chloride, potassium chloride, lithium nitrate, sodium
nitrate, potassium nitrate, lithium sulfate, sodium sulfate, potassium sulfate, sodium
monohydrogen phosphate, potassium monohydrogen phosphate, sodium
dihydrogen phosphate, potassium dihydrogen phosphate and the like. Mixtures can
also be used to create a pH-adjusters or buffers or neutralizing agents. However,
those skilled in the art will appreciate that it is possible to utilize other
conventionally known pH-adjusters or buffers or neutralizing agents without
departing from the scope of the present invention.
According to an embodiment, the pH-adjuster or buffer is present in an amount of
0.01% to 20% w/w of the total composition. According to an embodiment, the pH-
adjuster or buffer is present in an amount of 0.01% to 10% w/w of the total
composition. According to an embodiment, the pH-adjuster or buffer is present in
an amount of 0.01% to 5% w/w of the total composition. According to an
embodiment, the pH-adjuster or buffer is present in an amount of 0.01% to 1% w/w
of the total composition.
According to an embodiment, the spreading agents which are used in the
agrochemical composition include, but not limited to one or more of cellulose
powder, dextrin, modified starch, crosslinked poly(vinylpyrrolidone), a copolymer
of maleic acid with a styrene compound, a (meth)acrylic acid copolymer, a half
Amended Specification
ester of a polymer consisting of polyhydric alcohol with dicarboxylic anhydride, a
water-soluble salt of polystyrenesulfonic acid, fatty acids, latex, aliphatic alcohols,
vegetable oils such as cottonseed, or inorganic oils, petroleum distillates, modified
trisiloxanes, polyglycol, polyethers, clatharates or salts or derivatives thereof.
However, those skilled in the art will appreciate that it is possible to utilize other
conventionally known spreading agents without departing from the scope of the
present invention.
According to an embodiment, the spreading agent is present in an amount of 0.1%
to 20% w/w of the total composition. According to an embodiment, the spreading
agent is present in an amount of 0.1% to 10% w/w of the total composition.
According to an embodiment, the spreading agent is present in an amount of 0.1%
to 5% w/w of the total composition. According to an embodiment, the spreading
agent is present in an amount of 0.1% to 1% w/w of the total composition.
According to an embodiment, the sticking agents which are used in the
agrochemical composition include, but not limited to one or more of paraffin, a
polyamide resin, polyacrylate, polyoxyethylene, wax, polyvinyl alkyl ether,
alkylphenol-formalin condensate, fatty acids, latex, aliphatic alcohols, vegetable
oils such as cottonseed, or inorganic oils, petroleum distillates, modified
trisiloxanes, polyglycol, polyethers, clatharates, a synthetic resin emulsion or salts
or derivatives thereof. However, those skilled in the art will appreciate that it is
possible to utilize other conventionally known sticking agents without departing
from the scope of the present invention.
According to an embodiment, the sticking agent is present in an amount of 0.1% to
% w/w of the total composition. According to an embodiment, the sticking agent
is present in an amount of 0.1% to 20% w/w of the total composition. According to
an embodiment, the sticking agent is present in an amount of 0.1% to 10% w/w of
the total composition.
Amended Specification
According to an embodiment, the stabilizers which are used in the agrochemical
composition include, but not limited to one or more of peroxide compounds such
as hydrogen peroxide and organic peroxides, alkyl nitrites such as ethyl nitrite and
alkyl glyoxylates such as ethyl glyoxylate, zeolite, antioxidants such as phenol
compounds, phosphoric acid compounds and the like; ultraviolet absorbers such as
benzophenone compounds or derivatives thereof. However, those skilled in the art
will appreciate that it is possible to utilize other conventionally known stabilizers
without departing from the scope of the present invention. suppliers.
According to an embodiment, the stabilizer is present in an amount of 0.1% to 30%
w/w of the total composition. According to an embodiment, the stabilizer is present
in an amount of 0.1% to 20% w/w of the total composition. According to an
embodiment, the stabilizer is present in an amount of 0.1% to 10% w/w of the total
composition.
According to an embodiment, the preservatives which are used in the agrochemical
composition include, but not limited to one or more of bactericides, anti-fungal
agents, biocides, anti-microbial agents, and antioxidant. Non limiting examples of
preservatives include one or more of paraben, its esters and salts, propionic acid
and its salts, 2,4-hexadienoic acid (sorbic acid) and its salt, formaldehyde and
paraformaldehyde, 2-hydroxybiphenyl ether and its salts, inorganic sulfites and
bisulfites, sodium iodate, chlorobutanol, dehydraacetic acid, formic acid, 1,6-bis(4-
amidinobromophenoxy)-n-hexane and its salts, 5-amino-1,3-bis(2-ethylhexyl)-
-methylhexahydropyrimidine, 5-bromonitro-1,3-dioxane, 2-bromo
nitropropane-1,3-diol, 2,4-dichlorobenzyl alcohol, N-(4-chlorophenyl)-N′-(3,4-
dichlorophenyl) urea, 4-chloro-m-cresol, 2,4,4′-trichloro-2′-hydroxy diphenyl
ether, 4-chloro-3,5-dimethyl phenol, 1,1′-methylene-bis(3-(1-hydroxy methyl-2,4-
dioximidazolidinyl)urea), poly(hexamethylenediguanide) hydrochloride, 2-
phenoxyethanol, hexamethylenetetramine, 1-(3-chloroallyl)-3,5,7-triazaazonia-
adamantane chloride, 1(4-chlorophenoxy)(1H-imidazolyl)-3,3-dimethyl
butanone, 1,3-bis(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione, benzyl
Amended Specification
alcohol, octopirox, 1,2-dibromo-2,4-dicyanobutane, 2,2′-methylenebis(6-bromo
chlorophenol), bromochlorophene, dichlorophene, 2-benzylchlorophenol, 2-
chloroacetamide, chlorhexidine, chlorhexidine acetate, chlorhexidine gluconate,
chlorhexidine hydrochloride, 1-phenoxypropanol, N-alkyl(C12-
C22)trimethylammonium bromide and chloride, 4,4-dimethyl-1,3-oxazolidine, N-
hydroxymethyl-N-(1,3-di(hydroxymethyl)-2,5-dioxoimidazolidinyl)-N′-
hydroxymethylurea, 1,6-bis(4-amidinophenoxy)-n-hexane and its salts,
glutaraldehyde, 5-ethylaza-3,7-dioxabicyclo(3.3.0)octane, 3-(4-
chlorophenoxy)propane-1,2-diol, Hyamine, alkyl(C8-C18)dimethylbenzyl
ammonium chloride, alkyl(C8-C18)dimethylbenzylammonium bromide, alkyl(C8-
C18)dimethylbenzylammonium saccharinate, benzyl hemiformal, 3-iodo
propynyl butylcarbamate, sodium hydroxymethylaminoacetate,
cetyltrimethylammonium bromide, cetylpyridinium chloride, and derivatives of 2H
isothiazolone (so-called isothiazolone derivatives) such as alkylisothiazolones
(for example 2-methyl-2H-isothiazolone, MIT; chloromethyl-2H-isothiazol-
3-one, CIT), benzoisothiazolones (for example 1,2-benzoisothiazol-3(2H)-one,
BIT, commercially available as Proxel® types from ICI) or 2-methyl-4,5-
trimethylene-2H-isothiazolone (MTIT), C1-C4-alkyl para-hydroxybenzoate, an
dichlorophene, Proxel® from ICI or Acticide® RS from Thor Chemie and Kathon®
MK from Rohm & Haas, Bacto-100, thimerosal, Sodium Propinoate, Sodium
Benzoate, Propyl Paraben,Propyl Paraben Sodum, Potassium Sorbate, Potassium
Benzoate, Phenyl Mercuric Nitrate, Phenyl Etehyl Alcohol, Sodium, Ethylparaben,
Methylparaben, Butylparaben, Bezyla Alcohol, Benzothonium Chloride,
Cetylpyridinium Chloride, Benzalkonium Chloride, 1,2-benzothiazolone,
Preventol® (Lanxess®), Butylhydroxytoluene, potassium sorbate, iodine-
containing organic compounds such as 3-bromo-2,3-diiodopropenyl ethyl
carbonate, 3-iodopropynyl butyl carbamate, 2,3,3-triiodo allyl alcohol, and
parachlorophenyliodopropargylformal; benzimidazole compounds and
benzthiazole compounds such as 2-(4-thiazolyl)benzimidazole and 2-
thiocyanomethylthiobenzo-thiazole; triazole compounds such as 1-(2-(2′,4′-
dichlorophenyl)-1,3-dioxolaneylmethyl)-1H-1,2,4-triazole, 1-(2-(2′,4′-dichloro
Amended Specification
phenyl)propyl-1,3-dioxolaneylmethyl)-1H-1,2,4-triazole, and α-(2-(4-
chlorophenyl) ethyl)-α-(1,1-dimethyl ethyl)-1H-1,2,4-triazoleethanol; and
naturally occurring compounds such as 4-isopropyl tropolone (hinokitiol) and
boraxor salts or derivatives thereof. Antioxidants includes but not limited to one or
more of imidazole and imidazole derivatives (e.g. urocanic acid), 4,4′-thiobist-
butylmethylphenol, 2,6-di-t-butyl-p-cresol (BHT), and pentaerythrityltetrakis[3-
(3,5,-di-t-butylhydroxyphenyl)]propionate; amine antioxidants such as N,N′-di-
2-naphthyl-p-phenylenediamine; hydroquinoline antioxidants such as 2,5-di(t-
amyl)hydroquinoline; phosphorus-containing antioxidants such as triphenyl
phosphate, carotenoids, carotenes (e.g. α-carotene, β-carotene, lycopene) and
derivatives thereof, lipoic acid and derivatives thereof (e.g. dihydrolipoic acid),
aurothioglucose, propylthiouracil and further thio compounds (e.g. thioglycerol,
thiosorbitol, thioglycolic acid, thioredoxin, N-acetyl, methyl, ethyl, propyl, amyl,
butyl, lauryl, palmitoyl, oleyl, γ-linoleyl, cholesteryl and glyceryl esters thereof),
and salts thereof, dilaurylthiodipropionate, distearylthiodipropionate,
thiodipropionic acid and derivatives thereof (esters, ethers, lipids, nucleotides,
nucleosides and salts), and sulfoximine compounds (e.g. buthioninesulfoximines,
homocysteine sulfoximine, buthionine sulfones, penta-, hexa-,
heptathioninesulfoximine) in very low tolerated doses (e.g. pmol/kg to pmol/kg),
α-hydroxy acids (e.g. citric acid, lactic acid, malic acid), humic acids, gallic esters
(e.g. propyl, octyl and dodecyl gallate), unsaturated fatty acids and derivatives,
hydroquinone and derivatives thereof (e.g. arbutin), ubiquinone and ubiquinol, and
derivatives thereof, ascorbyl palmitate, stearate, di- palmitate, acetate, Mg ascorbyl
phosphates, diso- diumascorbyl phosphate and sulfate, potassium
ascorbyltocopheryl phosphate, isoascorbic acid and derivatives thereof, the
coniferyl benzoate of benzoin resin, rutin, rutinic acid and derivatives thereof,
disodium rutinyldisulfate, dibutylhydroxytoluene, 4,4-thiobistert-butyl
methylphenol, butylhydroxy anisole, p-octylphenol, mono-(di- or tri-) methyl
benzylphenol, 2,6-tert-butylmethylphenol, pentaerythritol-tetrakis 3-(3,5-di-
tert-butylhydroxyphenyl)propionate, butylhydroxyanisol, nordihydroguaiacic
acid, nordihydroguaiaretic acid, trihydroxybutyrophenone, uric acid and derivatives
Amended Specification
thereof, mannose and derivatives thereof, selenium and selenium derivatives (e.g.
selenomethionine), stilbenes and stilbene derivatives (e.g. stilbene oxide, trans-
stilbene oxide) and mixtures thereof. However, those skilled in the art will
appreciate that it is possible to utilize other conventionally known preservatives
without departing from the scope of the present invention.
According to an embodiment, the preservative or bactericide or anti-fungal agent
or biocide or anti-microbial agent or antioxidant is present in an amount of 0.1% to
% w/w of the total composition. According to further embodiment, the
preservative or bactericide or anti-fungal agent or biocide or anti-microbial agent
or antioxidant is present in an amount of 0.1% to 10% w/w of the total composition.
According to further embodiment, the preservative or bactericide or anti-fungal
agent or biocide or anti-microbial agent or antioxidant is present in an amount of
0.1% to 5% w/w of the total composition. According to further embodiment, the
preservative or bactericide or anti-fungal agent or biocide or anti-microbial agent
or antioxidant is present in an amount of 0.1% to 1% w/w of the total composition.
According to an embodiment, the structuring agents which are used in the liquid
composition include, but not limited to one or more of thickeners, viscosity
modifiers, tackifiers, suspension aids, rheological modifiers or anti-settling agents.
A structuring agent prevents sedimentation of the active ingredient particles after
prolonged storage.
According to an embodiment, the structuring agents which are used in the liquid
composition include, but not limited to one or more polymers such as polyacrylics,
polyacrylamides, polysaccharides, hydrophobically modified cellulose derivatives,
co-polymers of cellulose derivatives, carboxyvinyl or polyvinyl pyrrolidones,
polyethylenes, polyethylene oxide, polyvinyl alcohol and derivatives; clays such as
bentonite clays, kaolin , smectite, attapulgites, attaclays with high surface area silica
and natural gums such as guar gum, xanthan gum, gum Arabic, gum tragacanth,
rhamsan gum, locust bean gum, carageenan, welan gum, veegum, gelatin, collagen;
Amended Specification
polyacrylic acids and their sodium salts; the polyglycol ethers of fatty alcohols and
polyethylene oxide or polypropylene oxide condensation products and mixtures
thereof and include ethoxylated alkyl phenols (also designated in the art as alkylaryl
polyether alcohols); ethoxylated aliphatic alcohols (or alkyl polyether alcohols);
ethoxylated fatty acids (or polyoxyethylene fatty acid esters);
ethoxylatedanhydrosorbitol esters (or polyethylene sorbitan fatty acid esters), long
chain amine and cyclic amine oxides which are nonionic in basic solutions; long
chain tertiary phosphine oxides; and long chain dialkyl sulfoxides, fumed silica,
mixture of fumed silica and fumed aluminium oxide, swellable polymers,
polyamides or its derivatives; polyols such as glycerine, poly(vinyl acetate), sodium
polyacrylate, poly(ethylene glycol), phospholipid (for example, cephalin, and the
like); stachyose, fructo-oligosaccharides, amylose, pectins, alginates, hydrocolloids
and mixtures thereof. Also, celluloses such as hemicellulose,
carboxymethylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxy-methyl
ethyl cellulose, hydroxyl ethyl propyl cellulose, methylhydroxyethylcellulose,
methylcellulose; starches such, starch acetates, starch hydroxyethyl ethers, ionic
starches, long-chain alkyl starches, dextrins, maltodextrin, corn starch, amine
starches, phosphates starches, and dialdehyde starches; plant starches such as corn
starch and potato starch; other carbohydrates such as pectin, dextrin, amylopectin,
xylan, glycogen, agar, gluten, alginic acid, phycocolloids, chitin or derivatives
thereof. However, those skilled in the art will appreciate that it is possible to utilize
other conventionally known structuring agents without departing from the scope of
the present invention.
Preferred structuring agents include one or more of xanthan gum, aluminum
silicate, methylcellulose, polysaccharide, alkaline earth metal silicate, gelatin, and
polyvinyl alcohol.
According to an embodiment, the structuring agent is present in an amount of 0.01%
to 10% w/w of the composition. According to an embodiment, the structuring agent
is present in an amount of 0.01% to 5% w/w of the composition. According to an
Amended Specification
embodiment, the structuring agent is present in an amount of 0.01% to 4% w/w of
the composition. According to an embodiment, the structuring agent is present in
an amount of 0.01% to 3% w/w of the composition. According to an embodiment,
the structuring agent is present in an amount of 0.01% to 2% w/w of the
composition. According to an embodiment, the structuring agent is present in an
amount of 0.01% to 1% w/w of the composition. According to an embodiment, the
structuring agent is present in an amount of 0.01% to 0.1% w/w of the composition.
According to an embodiment, the anti- freezing agents or freezing point depressants
used in the liquid composition include, but not limited to one or more of polyhydric
alcohols such as ethylene glycol, diethylene glycol, dipropylene glycol, propylene
glycol, butyrolactone, N,N-dimethyl-formamide, glycerol, monohydric or
polyhydric alcohols, glycol ethers, glycol ethers, glycol monoethers such as the
methyl, ethyl, propyl and butyl ether of ethylene glycol, diethylene glycol,
propylene glycol and dipropylene glycol, glycol diethers such as methyl and ethyl
diethers of ethylene glycol, diethylene glycol and dipropyleneglycol.or urea,
glycerol, isopropanol, propylene glycol monomethyl ether, di- or tripropylene
glycol monomethyl ether or cyclohexanol, carbohydrates such as glucose, mannose,
fructose, galactose, sucrose, lactose, maltose, xylose, arabinose, sorbitol, mannitol,
trehalose, raffinose or derivatives thereof. However, those skilled in the art will
appreciate that it is possible to utilize different anti-freezing agents without
departing from the scope of the present invention.
According to an embodiment, the chelating or complexing or sesquitering
sequestering agents which are used in the liquid composition include, but not
limited to one or more of polycarboxylic acids such as polyacrylic acid and the
various hydrolyzed poly(methyl vinyl ether/maleic anhydride); N-
hydroxyethyliminodiacetic acid, nitrilotriacetic acid (NTA), N,N,N',N'-
ethylenediaminetetraacetic acid, N-hydroxyethyl-N, N',N'-
ethylenediaminetriacetic acid and N,N,N',N",N"-diethylenetriaminepentaacetic
acid; α-hydroxy acids, such as citric acid, tartaric acid and gluconic acid;
Amended Specification
orthophosphates, such as trisodium phosphate, disodium phosphate, monosodium
phosphate; condensed phosphates, such as sodium tripolyphosphate, tetrasodium
pyrophosphate, sodium hexametaphosphate and sodium tetrapolyphosphate; 5-
sulfohydroxyquinoline; and 3,5-disulfopyrocatechol, polycarboxylates, ethylene
diamine tetraacetic acid (EDTA), diethylenetriaminepentaacetic acid (DTPA), N-
hydroxyethyl-ethylenediamine-triacetic acid (HEDTA), ethylenediaminediacetate
(EDDA), ethylenediaminedi(o-hydroxyphenylacetic) acid (EDDHA), cyclohexane
diamine tetraacetic acid (CDTA), polyethyleneaminepolyacetic acids,
lignosulfonate, Ca-, K-, Na-, and ammonium lignosulfonates, fulvic acid, ulmic
acid, nucleic acids, cyclodextrin, humic acid, pyrophosphate. However, those
skilled in the art will appreciate that it is possible to utilize other chelating or
complexing or sesquitering agents without departing from the scope of the present
invention.
According to an embodiment, the penetrants which are used in the liquid
composition include, but not limited to one or more of alcohol, glycol, glycol ether,
ester, amine, alkanolamine, amine oxide, quaternary ammonium compound,
triglyceride, fatty acid ester, fatty acid ether, N-methyl pyrrolidone,
dimethylformamide, dimethylacetamide, or dimethyl sulfoxide, polyoxyethylene
trimethylolpropanemonooleate, polyoxyethylene trimethylolpropanedioleate,
polyoxyethylenetrimethylolpropanetrioleate, polyoxyethylenesorbitanmonooleate,
polyoxyethylene sorbitol hexaoleate. However, those skilled in the art will
appreciate that it is possible to utilize different penetrants without departing from
the scope of the present invention.
According to an embodiment, the ultraviolet absorbent which are used in the
agrochemical composition include, but not limited to one or more of 2-(2'-hydroxy-
'-methylphenyl)benzotriazole, 2-ethoxy-2'-ethyloxazalic acid bisanilide, succinic
acid dimethyl(2-hydroxyethyl)hydroxy-2,2,6,6-tetramethylpiperidine
polycondensate, benzotriazole compounds such as 2-(2′-hydroxy-5′-
methylphenyl)benzotriazole and 2-(2′-hydroxy-4′-n-octoxyphenyl)benzotriazole;
Amended Specification
benzophenone compounds such as 2-hydroxymethoxybenzophenone and 2-
hydroxyn-octoxybenzophenone; salicylic acid compounds such as phenyl
salicylate and p-t-butylphenyl salicylate; 2-ethylhexyl 2-cyano-3,3-diphenyl
acrylate, 2-ethoxy-2′-ethyl oxalic bisanilide, and dimethyl succinate(2-
hydroxyethyl)hydroxy-2,2,6,6-tetramethylpiperidine polycondensate or
derivatives or the like. However, those skilled in the art will appreciate that it is
possible to utilize different ultraviolet absorbents, without departing from the scope
of the present invention.
According to an embodiment, the UV ray scattering agents which are used in the
agrochemical composition include, but not limited to titanium dioxide or the like
may be used. However, those skilled in the art will appreciate that it is possible to
utilize different UV ray scattering agents or mixtures thereof without departing
from the scope of the present invention.
According to an embodiment, the humectants which are used in the agrochemical
composition include, but not limited to one or more of
polyoxyethylene/polyoxypropylene copolymers, particularly block copolymers,
such as the Synperonic PE series of copolymers available from Uniqema or salts,
derivatives thereof. Other humectants are propylene glycol, monoethylene glycol,
hexylene glycol, butylene glycol, ethylene glycol, diethylene glycol, poly (ethylene
glycol), poly (propylene glycol), glycerol and the like; polyhydric alcohol
compounds such as propylene glycol ether, derivatives thereof. Also other
humectants include aloe vera gel, alpha hydroxyl acids such as lactic acid, glyceryl
triacetate, honey, lithium chloride, etc. The non-ionic surfactants mentioned above
also act as humectants. However, those skilled in the art will appreciate that it is
possible to utilize other conventionally known humectants without departing from
the scope of the present invention.
According to an embodiment, the humectant is present in the range of 0.1% to 90%
w/w of the total composition. According to an embodiment, the humectant is
Amended Specification
present in the range of 0.1% to 70% w/w of the total composition. According to an
embodiment, the humectant is present in the range of 0.1% to 60% w/w of the total
composition. According to an embodiment, the humectant is present in the range of
0.1% to 50% w/w of the total composition. According to an embodiment, the
humectant is present in the range of 0.1% to 30% w/w of the total composition.
According to an embodiment, the humectant is present in the range of 0.1% to 10%
w/w of the total composition.
According to an embodiment, the organic fluids which are used in agrochemical
composition include, but not limited to one or more of aromatic and non-aromatic
hydrocarbons, halogenated aromatic and non- aromatic hydrocarbons, aromatic and
non-aromatic ethers, esters or amides and oils. According to further embodiment
the oils include but not limited to, one or more of a mineral oil, petroleum oil,
vegetable oil or animal oil or derivatives or mixtures thereof. However, those
skilled in the art will appreciate that it is possible to utilize other oils without
departing from the scope of the present invention.
According to an embodiment, the mineral oil or petroleum oil include, but not
limited to one or more of aliphatic or isoparaffinic series and mixtures of aromatic
and aliphatic hydrocarbons; halogenated aromatic or aliphatic hydrocarbons.
Paraffinic oil includes, but not limited to one or more of linear or branched C8 to
C30 paraffins for example such as octane, nonane, decane, undecane, dodecane,
tridecane, tetradecane, pentadecane, hexadecane or their mixtures and mixtures
thereof with higher boiling homologs, such as hepta-, octa-, nona-decane, eicosane,
heneicosane, docosane, tricosane, tetracosane, pentacosane, and the branched chain
isomers thereof, unsubstituted or substituted aromatic or cycloaliphatic C7 to C18
hydrocarbon compounds such as mono- or polyalkyl-substituted benzenes, or
mono- or polyalkyl-substituted naphthalenes, or transesterification products
thereof, liquid esters of C1 to C12 alcohols such as butanol, n-octanol, i-octanol,
dodecanoi, cyclopentanol, cyclohexanol, cyclooctanol, ethylene glycol or
propylene glycol with C2 to C12 carboxylic or polycarboxylic acids, such as
Amended Specification
caproic acid, capric acid, caprylic acid, peiargonic acid, succinic acid and glutaric
acid; or with aromatic carboxylic acids such as benzoic acid, toluic acid, salicylic
acid and phthalic acid , liquid amides of C1 to C5 amines, alkylamines or
alkanolamines with C6 to C18 carboxylic acids, or derivatives thereof. Esters which
are used in the oil dispersions of the invention include, but not limited to one or
more of benzyl acetate, caproic acid ethyl ester, peiargonic acid ethyl ester, benzoic
acid methyl or ethyl ester, salicylic acid methyl, propyl, or butyl ester, diesters of
phthalic acid with saturated aliphatic or alicyclic C1 to C12 alcohols, such as
phthalic acid dimethyl ester, dibutyl ester, diisooctyt ester, or liquid amides of C1-
C3 amines, alkylamines or alkanolamines with C6 - C18 carboxylic acids or
derivatives and mixtures thereof. However, those skilled in the art will appreciate
that it is possible to utilize other mineral or petroleum oils without departing from
the scope of the present invention.
According to an embodiment, the vegetable oils include, but not limited to one or
more of seed oil. The vegetable oils include but not limited to, one or more of soy
bean oil, rape seed oil, olive oil, castor oil, sunflower seed oil, coconut oil, corn oil,
cotton seed oil, linseed oil, palm oil, peanut oil, saffiower oil, sesame oil, kapok oil,
papaya oil, camellia oil, rice bran oil, tung oil and the like; and esters of the above
vegetable oils, or transesterification products thereof such as soy bean oil methyl
esters, ethyl esters, propyl esters, butyl esters or derivatives thereof. The animal oils
include, but not limited to one or more of whale oil, cod-liver oil, or mink oil.
However, those skilled in the art will appreciate that it is possible to utilize other
vegetable or animal oils without departing from the scope of the present invention.
The inventors have further determined that the composition of the present invention
has excellent physical properties of dispersibility, suspensibility, flowability,
disintegration, wetting time, viscosity, stability, pourability, provides ease of
handling and also reduces the loss of material while handling the product at the time
of packaging as well as during field application.
Amended Specification
Dispersibility of the water dispersible, micro granular agrochemical composition is
a measure of percent dispersion. Dispersibility is calculated by the minimum
percent dispersion. Dispersibility is defined as the ability of the granules to disperse
upon addition to a liquid such as water or a solvent. To determine dispersibility of
the granular composition as per the standard CIPAC test, MT 174, a known amount
of the granular composition was added to a defined volume of water and mixed by
stirring to form a suspension. After standing for a short period, the top nine-tenths
are drawn off and the remaining tenth dried and determined gravimetrically. The
method is virtually a shortened test of suspensibility and is appropriate for
establishing the ease with which the granular composition dispersed uniformly in
water.
According to an embodiment, the agrochemical composition in the form of solid
especially water dispersible granules and micro granules exhibits almost
instantaneous dispersion thus making the actives readily available to the crops.
According to an embodiment, the agrochemical composition has a dispersibility of
at least 30%. According to an embodiment, the agrochemical composition has a
dispersibility of at least 40%. According to an embodiment, the agrochemical
composition has a dispersibility of at least 50%. According to an embodiment, the
agrochemical composition has a dispersibility of at least 60%. According to an
embodiment, the agrochemical composition has a dispersibility of at least 70%.
According to an embodiment, the agrochemical composition has a dispersibility of
at least 80%. According to an embodiment, the agrochemical composition has a
dispersibility of at least 90%. According to an embodiment, the agrochemical
composition has a dispersibility of at least 99%. According to an embodiment, the
agrochemical composition has a dispersibility of 100%.
Disintegration is defined as the complete breakdown exhibited by the granules on
coming in contact with soil moisture or water. The Samples can be tested for
disintegration time as per the CIPAC Handbook, "MT 197 for Disintegration of
Amended Specification
tablets”. To carry out the test one entire water disintegrable granule is added to a
defined volume of CIPAC standard water and mixed by gentle stirring for the
specified disintegration time of the tablet. The suspension is then passed through a
2000μm sieve. The absence of a residue on the screen indicates complete
disintegration of the tablet.
According to an embodiment, the agrochemical composition in the form of water
disintegrable granules or broadcast granules exhibits superior properties of
disintegration. According to an embodiment, the disintegration time exhibited by
the agrochemical composition is at least 120 minutes. According to an embodiment,
the disintegration time exhibited by the agrochemical composition is at least 90
minutes. According to an embodiment, the disintegration time exhibited by the
agrochemical composition is at least 70 minutes. According to an embodiment, the
disintegration time exhibited by the agrochemical composition is at least 50
minutes. According to an embodiment, the disintegration time exhibited by the
agrochemical composition is at least 30 minutes. According to an embodiment, the
disintegration time exhibited by the agrochemical composition is at least 20
minutes. According to an embodiment, the disintegration time exhibited by the
agrochemical composition is at least 10 minutes. According to an embodiment, the
disintegration time exhibited by the agrochemical composition is at least 5 minutes.
It is possible that the agrochemical composition of the present invention can be
formulated in a manner such that it readily disintegrates and can even disintegrate
in less than 5 minutes. The disintegration time is estimated by disintegration testing
equipments such as the ones provided by Electrolab Edutec, Arentek and Shimadzu.
According to an embodiment, the agrochemical composition exhibits good
suspensibility. Suspensibility is defined as the amount of active ingredient
suspended after a given time in a column of liquid, of stated height, expressed as a
percentage of the amount of active ingredient in the original suspension. The water
dispersible granules can be tested for suspensibility as per the CIPAC Handbook,
"MT 184 Test for Suspensibility” whereby a suspension of known concentration
Amended Specification
of the composition in CIPAC Standard Water was prepared and placed in a
prescribed measuring cylinder at a constant temperature, and allowed to remain
undisturbed for a specified time. The top 9/10ths were drawn off and the remaining
1/10th was then assayed chemically, gravimetrically, or by solvent extraction, and
the suspensibility was calculated.
The suspensibility of the liquid suspension is the amount of active ingredient
suspended after a given time in a column of liquid, of stated height, expressed as a
percentage of the amount of active ingredient in the original suspension. The
suspensibility of liquid suspension concentrate is determined as per CIPAC MT-
161 by preparing 250 ml of diluted suspension, allowing it to stand in a measuring
cylinder under defined conditions, and removing the top nine-tenths. The remaining
tenth is then assayed chemically, gravimetrically or by solvent extraction, and the
suspensibility is calculated.
According to an embodiment, the agrochemical composition has a suspensibility of
at least 30%. According to an embodiment, the agrochemical composition of at least
40%. According to an embodiment, the agrochemical composition has a
suspensibility of at least 50%. According to an embodiment, the agrochemical
composition has a suspensibility of at least 60%. According to an embodiment, the
agrochemical composition has a suspensibility of at least 70%. According to an
embodiment, the agrochemical composition has a suspensibility of at least 80%.
According to an embodiment, the agrochemical composition has a suspensibility of
at least 90%. According to an embodiment, the agrochemical composition has a
suspensibility of at least 99%. According to an embodiment, the agrochemical
composition has a suspensibility of 100%.
According to an embodiment, the agrochemical composition demonstrates superior
stability towards heat, light, temperature and caking. The composition does not
form a hard cake and exhibits enhanced stability even at extended storage under
higher temperatures which in turn results in superior field performance. According
Amended Specification
to further embodiment, the stability exhibited by the agrochemical composition is
at least 3 years. According to further embodiment, the stability exhibited by the
agrochemical composition is at least 2 years. According to further embodiment, the
stability exhibited by the agrochemical composition is at least 1 year. According to
further embodiment, the stability exhibited by the agrochemical composition is at
least 6 months.
Wettability is the condition or the state of being wettable and can be defined as the
degree to which a solid is wetted by a liquid, measured by the force of adhesion
between the solid and liquid phases. The wettability of the granular composition is
measured using the Standard CIPAC Test MT-53 which describes a procedure for
the determination of the time of complete wetting of wettable formulations. A
weighed amount of the granular composition is dropped on water in a beaker from
a specified height and the time for complete wetting was determined. According to
another embodiment, the agrochemical composition in the form of water dispersible
granules, micro granules and broadcast granules has wettability of less than 2
minutes. According to another embodiment, the agrochemical composition in the
form of water dispersible granules, micro granules and broadcast granules has
wettability of less than 1 minute. According to another embodiment, the
agrochemical composition in the form of water dispersible granules, micro granules
and broadcasrt granules has wettability of less than 30 seconds.
According to an embodiment, the agrochemical composition passes the wet sieve
retention test. The test is used to determine the amount of non-dispersible material
in formulations that are applied as dispersions in water. The wet sieve retention
value of the agrochemical composition in the form of liquid suspension and water
dispersible granules is measured by using the Standard CIPAC Test MT-185 which
describes a procedure for the measuring the amount of material retained on the
sieve. A sample of the formulation is dispersed in water and the suspension formed
is transferred to a sieve and washed. The amount of the material retained on the
sieve is determined by drying and weighing.
Amended Specification
According to an embodiment, the agrochemical composition has a wet sieve
retention value on a 75 micron sieve of less than 10%. According to an embodiment,
the agrochemical composition has a wet sieve retention value on a 75 micron sieve
of less than 7%. According to an embodiment, the agrochemical composition has a
wet sieve retention value on a 75 micron sieve of less than 5%. According to an
embodiment, the agrochemical composition has a wet sieve retention value on a 75
micron sieve of less than 2%.
According to an embodiment, viscosity of the liquid composition is determined as
per CIPAC MT-192. A sample is transferred to a standard measuring system. The
measurement is carried out under different shear conditions and the apparent
viscosities are determined. During the test, the temperature of the liquid is kept
constant. According to an embodiment, the agrochemical composition has a
viscosity at 25° C. of about 10 cps to about 3000 cps. According to an embodiment,
the agrochemical composition has a viscosity at 25° C. of about 10 cps to about
2500 cps. According to an embodiment, the agrochemical composition has a
viscosity at 25° C. of about 10 cps to about 2000 cps. According to an embodiment,
the agrochemical composition has a viscosity at 25° C. of about 10 cps to about
1500 cps. According to an embodiment, the agrochemical composition has a
viscosity at 25° C. of about 10 cps to about 1200 cps. According to an embodiment,
the agrochemical composition has viscosity at 25° C. of about 10 cps to about 500
cps. According to an embodiment, the agrochemical composition has a viscosity at
° C. of about less than 500 cps. According to an embodiment, the agrochemical
composition has viscosity at 25° C. of about 10 cps to about 400 cps. According to
an embodiment, the agrochemical composition has viscosity at 25° C. of about 10
cps to about 300 cps.
According to an embodiment, the agrochemical composition demonstrates superior
stability in terms of suspensibility under accelerated storage condition (ATS).
According to an embodiment, the agrochemical composition demonstrates
Amended Specification
suspensibility of more than 90% under ATS. According to an embodiment, the
agrochemical composition demonstrates suspensibility of more than 80% under
ATS. According to an embodiment, the agrochemical composition demonstrates
suspensibility of more than 70% under ATS. According to an embodiment, the
agrochemical composition demonstrates suspensibility of more than 60% under
ATS. According to an embodiment, the agrochemical composition demonstrates
suspensibility of more than 50% under ATS. According to an embodiment, the
agrochemical composition demonstrates suspensibility of more than 40% under
ATS. According to an embodiment, the agrochemical composition demonstrates
suspensibility of more than 30% under ATS.
According to an embodiment, the invention relates to a process for preparing the
agrochemical composition comprising a complex formed with at least one of
elemental zinc or its salt or derivative thereof and at least one of eugenol or a source
thereof; and at least one agrochemical excipient.
According to an embodiment, the process for preparing the agrochemical
composition further includes at least one of nutrient, biostimulants, pesticidal
actives, plant growth regulators, microbes, algae, bacteriospores, fertilizers or salts
or complexes or derivatives or mixtures thereof.
According to further embodiment, the complex formed with at least one of
elemental zinc or its salt or derivative thereof and at least one of eugenol or a source
thereof; as per the invention may be prepared as outlined below. Briefly one of the
complex formation technique; wherein zinc is in the form of zinc oxide involves
reacting one mole of zinc oxide to 2 moles of eugenol in presence of one or more
of accelerator or plasticizer such as zinc stearate, zinc acetate; wherein the ratio of
zinc oxide to eugenol is 19:79. Alternatively, the process may be varied by keeping
the ratio of zinc oxide to eugenol is 44:55. However, those skilled in the art will
appreciate that it is possible to utilize other techniques without departing from the
scope of the present invention.
Amended Specification
According to further embodiment, the invention relates to a process for preparing
the agrochemical composition, wherein the composition is in the form of
suspoemulsion, emulsion in water, oil dispersion or suspension, water dispersible
granules, broadcast granules, water disintegrable granules, micro granules, liquid
suspension, aqueous suspension, suspension concentrate, wettable powder,
emulsifiable concentrate and seed dressing or emulsions for seed treatment and
combinations thereof.
The agrochemical composition of the present invention is made by various means
depending on the nature of the formulation to which the present invention relates.
According to another embodiment, the invention relates to a process for preparing
the solid agrochemical composition in the form of water dispersible granules,
broadcast granules, water disintegrable granules, micro granules, wettable powder.
According to another embodiment, the agrochemical composition in the form of
water dispersible granules, broadcast granules, water disintegrable granules, micro
granules is made by various techniques such as spray drying, fluidized bed
granulation, pan granulation, extrusion, freeze drying etc.
According to an embodiment, the process of preparing a water dispersible granular
or micro granular composition involves milling a blend of a complex formed with
at least one of elemental zinc or its salt or derivative thereof and at least one of
eugenol or a source thereof; with at least one agrochemical excipient to obtain slurry
or a wet mix. The wet mix obtained is then dried, for instance in a spray dryer, fluid
bed dryer or any suitable granulating equipment, followed by sieving to remove the
undersized and oversized granules to obtain water dispersible granules or
microgranules of the desired size if required. However, those skilled in the art will
appreciate that it is possible to modify or alter or change the process or process
Amended Specification
parameters to obtain water dispersible granular or micro granular composition
without departing from the scope of the present invention.
According to another embodiment, the agrochemical composition in the form of
water dispersible granules or micro granules is also made by dry milling a complex
formed with at least one of elemental zinc or its salt or derivative thereof and at
least one of eugenol or a source thereof; and at least one agrochemical excipient in
an air mill or a jet mill to obtain the desired particle size in the range of 0.1 to 50
microns. Water is added to the dry powder and the mixture is blended to obtain a
dough or paste, which is then extruded through an extruder to obtain the granules
of desired size. The granules can also be formed with low melt extrusion. However,
those skilled in the art will appreciate that it is possible to modify or alter or change
the process or process parameters to obtain water dispersible granular or micro
granular composition without departing from the scope of the present invention.
According to an embodiment, the process of preparing a wettable powder
composition involves milling a blend of a complex formed with at least one of
elemental zinc or its salt or derivative thereof and at least one of eugenol or a source
thereof; with at least one agrochemical excipient to obtain wettable powder
composition with desired particle size. Further, broadcast granules, water
disintegrable granules can be made by various processes such as pelletization,
compaction, agglomeration or other techniques known in the art. However, those
skilled in the art will appreciate that it is possible to modify or alter or change the
process or process parameters to obtain wettable powder, broadcast granular, water
disintegrable granular composition without departing from the scope of the present
invention.
According to another embodiment, the invention relates to a process for preparing
the liquid agrochemical composition in the form of suspoemulsion, emulsion in
water, oil dispersion or suspension, liquid suspension, aqueous suspension,
Amended Specification
suspension concentrate, emulsifiable concentrate and seed dressing or emulsions
for seed treatment and combinations thereof.
According to an embodiment, the process of preparing the liquid suspension,
aqueous suspension, suspension concentrate involves homogenization of one or
more of excipients by feeding them into a vessel provided with stirring facilities.
The complex formed with at least one of elemental zinc or its salt or derivative
thereof and at least one of eugenol or a source thereof; are added to the
homogenized blend and stirred continuously for about 5 to 10 minutes until the total
mixture becomes homogeneous. Subsequently, the suspension obtained is passed
through the wet mill to obtain a desired particle size in the range of 0.1 to 50
microns. Then, requisite quantity of the structuring agent is added to the obtained
suspension, under continuous homogenization. However, those skilled in the art
will appreciate that it is possible to modify or alter or change the process or process
parameters to obtain liquid suspension, aqueous suspension, suspension concentrate
composition without departing from the scope of the present invention.
The liquid suspension, aqueous suspension, suspension concentrate composition
can be further mixed with aqueous emulsion containing at least one fertilizer,
nutrients, pesticidal actives, biostimulants, plant growth regulators, algae,
microbes, bacteriospores, salts, derivatives, complexes or mixtures thereof in
presence of at least one agrochemical excipient; to obtain suspoemulsion
composition of desired size. However, those skilled in the art will appreciate that it
is possible to modify or alter or change the process or process parameters to obtain
suspoemulsion composition without departing from the scope of the present
invention.
According to an embodiment, the gel composition of the present invention is
prepared by adding more amounts of viscosity modifiers to the suspension
concentrate composition. However, those skilled in the art will appreciate that it is
Amended Specification
possible to modify or alter or change the process or process parameters to obtain
gel composition without departing from the scope of the present invention.
According to an embodiment, the invention further relates to the process of
preparation of the agrochemical composition in the form of oil dispersion. The
process involves mixing an oil, a complex formed with at least one of elemental
zinc or its salt or derivative thereof and at least one of eugenol or a source thereof;
one or more of emulsifier or surfactant and optionally one or more other
agrochemical excipients such as rheology modifiers under high shear, thereby
grinding the sample to desired particle size to obtain the oil dispersion composition.
However, those skilled in the art will appreciate that it is possible to modify or alter
or change the process or process parameters to obtain oil dispersion composition
without departing from the scope of the present invention.
According to an embodiment, the composition of the present invention is at least
one of a pesticide composition, a nutrient composition, a crop strengthener
composition, a crop protection, a yield enhancer composition, a fungicide
composition, a bactericide composition and a fertilizer composition.
According to an embodiment, the invention further relates to a method of protecting
the crop, improving the crop health and growth, enhancing the crop yield,
strengthening the plant, increasing crop defense, protecting crops from biotic and
abiotic stresses or conditioning the soil; the method comprising treating at least one
of seeds, seedling, crops, a plant, plant propagation material, locus, parts thereof or
to the surrounding soil with effective amount of the agrochemical composition
which includes a complex formed with at least one of elemental zinc or its salt or
derivative thereof and at least one of eugenol or a source thereof; with at least one
agrochemical excipient.
The composition is applied through a variety of methods. Methods of applying to
the soil include any suitable method, which ensures that the composition penetrates
Amended Specification
the soil, for example nursery tray application, in furrow application, soil drenching,
soil injection, drip irrigation, sprinker irrigation, seed treatment, seed painting and
such other methods. The composition also is applied in the form of a foliar spray.
The rates of application or the dosage of the composition depends on the type of
use, the type of crops, or the specific active ingredients in the composition but is
such that the agrochemical active ingredient, in an effective amount to provide the
desired action.
According to an embodiment, the composition of the present invention is effective
in controlling growth of plant pathogens such as bacteria, fungi, nematodes,
protists, virus as well as pests such as insects, acarids, and the like.
A. PREPARATION EXAMPLES:
The following examples illustrate the basic methodology and versatility of the
composition of the invention. Sources of zinc, eugenol are exemplified in the
preparatory examples and can be replaced by any other sources of zinc, eugenol. It
should be noted that this invention is not limited to these exemplifications and can
be extrapolated to overall claimed concentration range of the components.
A. Solid Agrochemical composition of a complex containing zinc and eugenol.
Example 1: Water dispersible granular composition comprising 40% complex
formed using zinc oxide and eugenol: Water dispersible granular composition was
prepared by blending 40 parts of a complex, 30 parts of naphthalene sulphonate
condensate, 20 parts of sodium lingo sulfonate, 10 parts of kaolin to obtain a blend.
The blend obtained was milled to get a powder of less than 50 microns particle size.
The powder was mixed with water in a suitable mixing equipment to form a slurry
or wet mix.
Amended Specification
The slurry obtained was wet ground in suitable wet grinding equipment. The wet
milled slurry obtained was spray dried at an inlet temperature less than 140°C and
outlet temperature less than 90°C to get a granular powder. The composition had
the following particle size distribution: D10 less than 2.5 microns; D50 less than
6.5 microns and D90 less than 18.1 microns. The granule size of the composition
was in the range of 0.1-2.5 mm. The composition had a dispersibility of 70%,
suspensibility of 75%, wet sieve retention value of 1.5%, wettability of less than 28
sec. The composition further demonstrated suspensibility of about 69% under
accelerated storage condition.
Example 2: Micro Granular composition comprising 80% complex formed using
zinc oxide and clove oil: This composition was prepared similar to Example 1 using
80 parts of complex, 11 parts of naphthalene sulfonic acid, 6 parts of starch and 3
parts of silica. The composition had the following particle size distribution: D10
less than 1.8 micron; D50 less than 5.2 microns and D90 less than 16.5 microns.
The granule size of the composition was in the range of 0.1-1.5 mm. The
composition had a dispersibility of 96%, suspensibility of 91%, wet sieve retention
value of 0.3% and wettability of less than 40 sec. The composition further
demonstrated suspensibility of about 85% under accelerated storage condition.
Example 3: Broadcast Granular composition of 65% complex formed using zinc
carbonate and combination of clove, cinnamon oil: This composition was prepared
using 65 parts of complex, 12 parts of sodium naphthalene formaldehyde
condensate, 10 parts of kaolin, 13 parts of cross linked carboxymethyl cellulose.
The composition had the following particle size distribution: D10 less than 3.5
microns; D50 less than 6.8 microns and D90 less than 20 microns. The granule size
of the composition was in the range of 0.1-5 mm. The composition had a
disintegration time of 10 minutes, wettability of less than 45 sec.
B. Liquid Agrochemical composition of a complex containing zinc and eugenol.
Amended Specification
Example 4: Liquid Suspension composition of 50% complex formed using zinc
oxide and eugenol: Liquid suspension composition was prepared by mixing 50 parts
of complex, 6 parts of naphthalene sulfonate condensate, 5 parts of propylene
glycol, 37 parts of water and homogenised by feeding them into a vessel provided
with stirring facilities until the total mixture was homogeneous. Subsequently, the
suspension obtained was passed through the wet mill to obtain a suspension with a
particle size of 0.1 to 50 microns. Then, 2 part of gum arabic (3%) was added under
continuous homogenization to obtain the suspension concentrate. The composition
had the particle size distribution of about D10 less than 2 microns; D50 less than
3.8 microns and D90 less than 8.5 microns. The sample had suspensibility of about
80%, viscosity of about 850 cps. The composition had suspensibility of about 75%
under accelerated storage condition.
Example 5: Liquid Suspension composition of 25% complex formed using
elemental zinc and clove oil: This composition was prepared similar to Example 6
using 25 parts of complex, 16 parts of naphthalene sulphonate condensate, 5 parts
of glycerol monolaurate, 14 parts of polyethylene glycol, 4 parts of 3% solution of
gum Arabic and 36 parts of water. The composition had the particle size distribution
of about D10 less than 3.0 microns; D50 less than 4.8 microns and D90 less than
10 microns. The sample had suspensibility of about 96%, viscosity of about 480
cps. The composition had suspensibility of about 92% under accelerated storage
condition.
Example 6: Suspoemulsion composition of 40% complex formed using zinc
carbonate and combination of clove oil, pepper oil: The liquid suspension
composition was prepared using 40 parts of complex, 4 parts of sodium alkyl
benzene sulfonate, 2 parts of sodium salt of polycarboxylic acid, 2 parts of perlite
and 30 parts of water. The said composition was blended with emulsifiable
concentrate composition prepared by using 15% pyraclostrobin in 7% petroleum
solvent to obtain suspoemulsion formulation. The composition had the following
particle size distribution: D10 less than 2.0 microns; D50 less than 5 microns and
Amended Specification
D90 less than 12 microns. The sample had suspensibility of about 91%, viscosity
of about 600 cps. The composition had suspensibility of about 86% under
accelerated storage condition.
Example 7: Oil Dispersion composition of 10% complex made using zinc oxide and
eugenol: The oil dispersion composition was obtained by heating 82 parts of methyl
Soyate, 1% silica at 80 -85 C. The resultant mixture was cooled, blended with 10
parts of complex, 6 parts of EO/PO Block Co-Polymer and homogenised by feeding
them into a vessel provided with stirring facilities until the total mixture was
homogeneous. Subsequently, the suspension obtained was passed twice through the
wet mill. Then, 1 part of silica was added under continuous homogenization to
obtain an oil dispersion composition with particle size less than 35 microns. The
sample had suspensibility of about 76%, viscosity of about 800 cps. The
composition had suspensibility of about 71% under accelerated storage condition.
FIELD STUDY:
To study effect of agrochemical composition of a complex according to an
embodiment of the present invention:
Experiment No. 1: Lab Trial (in-vivo anti-fungal test) was conducted for the
evaluation of an efficacy of the composition of the present invention on strains of
various fungal pathogens such as Rhizoctonia spps. causing root rot disease,
Fusarium oxysporum causing wilt disease, Aspergillus niger causing collar rot
disease, Colletorichium spps causing anthracnose disease, Sclerotium rolfsii
causing stem rot disease at different concentrations of the composition.
The treatments (T1 and T2) with the compositions of the present invention as
mentioned below were screened by the “Agar Plate Assay method” at
concentrations of 1000 ppm, 2000 ppm and 5000 ppm respectively against the fungi
pathogens as mentioned above. The observations on average colony diameter of
Amended Specification
fungal pathogen were recorded and presented in Table 1 in form of % inhibition of
the mycelial growth.
Table 1: Evaluation of the composition of present embodiment against pathogenic
fungi in vitro.
T1: 25% SC composition of complex as per the embodiment of the present
invention;
T2: 40% WDG composition of complex as per the embodiment of the present
invention;
% Inhibition of mycelial growth of different pathogenic fungi
Fusariu
Rhizocto
Concentrations of
m Aspergillu Colletoric Sclerotium
active ingredient
oxysporu s niger hium spps rolfsii
solani
(a.i.)
1000 ppm 60.7 77.0 30.3 52.7 68.3
T1 2000 ppm 100.0 100.0 87.3 95.7 100.0
5000 ppm 100.0 100.0 100.0 100.0 100.0
1000 ppm 53.7 44.0 51.3 80.3 56.7
T2 2000 ppm 100.0 87.3 92.0 100.0 100.0
5000 ppm 100.0 100.0 100.0 100.0 100.0
It was noted that treatments T1 and T2 according to an embodiment of the present
invention appear as effective treatments to control the pathogen Rhizoctoni a spps.
Amended Specification
It can be seen from Table 1 that the % growth control with T1 and T2 according to
an embodiment of the present invention at an active ingredient concentration of
1000 ppm was about 60.7% and 53.7% respectively whereas at a concentration of
2000 ppm, 5000 ppm, it was about 100% for both the treatments. Thus, the
composition of the complex in the form of water dispersible granules and
suspension concentrate illustrates excellent effect against tested fungus at a dosage
of 2000 ppm and 5000 ppm. Further, it was observed that the compositions of the
present invention T1, T2 show incremental efficacy when tested from 1000 to 5000
ppm of the active ingredient complex.
Similarly, as can be seen from the Table 1, the composition of the present invention
was found to be efficacious in controlling the other tested fungus.
Experiment No. 2: To assess the effect of composition of complex of the present
invention against Citrus Canker disease (a bacterial disease) on Lemon.
Evaluation of efficacy of agrochemical composition of the present invention in the
form of water dispersible granules as well as suspension concentrate against Citrus
Canker disease in Lemon was done at Akola in Maharashtra
Field Experiment Methodology:
The trial was laid out during kharif season in Randomized Block Design (RBD) for
treatments as described below including untreated control, replicated three times.
Example-1: 25% SC composition of Complex as per the embodiment of the present
invention;
Example-2: 40% WDG composition of Complex as per the embodiment of the
present invention
Amended Specification
For each treatment, three plants were tagged and replicated thrice. The treatments
as per treatment details mentioned below were applied as foliar spray twice at the
interval of 15 days between two sprays. First spray was started immediately after
occurrence of initial disease symptoms on plant leaves and fruits. Twenty infected
leaves and fruit selected randomly were tagged and labeled just before application
of treatment in each plot/plants.
Details of experiment
a) Trial Location : Akola (Maharashtra)
b) Crop : Citrus
c) Experiment season : Rabi 2018-19 (July to October)
d) Trial Design : Randomized Block Design
e) Replications : Three
f) Treatment : Seven
g) No of plant /treat. : Three
st nd
h) Date of Applications: 1 =29.07.2018; 2 = 14.08.2018
j) Method of application: Foliar spray using 5 L water per plant
The progress of the disease on both leaves and fruits was recorded 20 days after
2nd spray using 0-5 rating scale and calculated percent disease control over
untreated plot is presented in Table 2. The fruit yield data was also recorded from
each picking and total yield from each plot was presented in Table 2. The percent
disease control was calculated using following formula.
Disease Control (%) = [Plant mortality in control plant – Plant mortality in treated
plant) / Plant Mortality in control plant] X 100
Table 2: Effect of composition of complex of the present invention against citrus
canker disease on Lemon.
Amended Specification
Treatments Dose (g.a.i./L % Disease control Marketable
water) Leaves Fruits Fruit yield
(kg/plant)
T1-Example-1 0.5 22.3 17.8 18.3
T2-Example-1 1.0 55.7 35.3 19.8
T3-Example-1 2.0 80.4 63.1 22.1
T4-Example-2 0.5 31.5 21.9 17.9
T5-Example-2 1.0 49.6 44.3 20.1
T6-Example-2 2.0 88.3 69.4 22.3
T7-Untreated - 0.0 0.0 15.3
check
From the data represented in Table 2, it was observed that treatment T3, according
to an embodiment of the present invention shows 80.4% and 63.1% disease control
in leaves and fruits respectively when compared with untreated control. Similarly,
treatment T6 according to an embodiment of the present invention shows 88.3%
and 69.4% diseases control in leaves and fruits respectively when compared with
untreated control, thus illustrating the highly efficacious nature of the compositions
of the present invention in terms of controlling bacterial disease.
The % disease control was superior at a dosage of 2 grams of active ingredient per
liter of water (as can be seen from T3 and T6), followed by % disease control at a
dosage of 1 gram of active ingredient per liter of water (as can be seen from T2 and
T5).
Further, it was also noticed that the compositions of the present invention at
different concentrations in the form of water dispersible granules and suspension
Amended Specification
concentrates depict significantly higher yields as compared to the untreated control
in lemon crop. For instance, T1-T6 as per the embodiment of the present invention
depicted fruit yield in range of about 17.9 kg/plant to 22.3 kg/plant whereas with
treatment T7 (untreated) the fruit yield was 15.3kg/plant.
Thus, it has been observed that the compositions of the present invention,
demonstrate enhanced, efficacious and superior results in the fields.
Further, it was observed that addition of other nutrients, pesticides, bio stimulants,
plant growth regulators, microbes, algae, bactereospores, fertilizer to the
composition of the present invention, apart from improving pesticidal activity may
further enhance crop characteristics, crop yield and add to nutritional value of the
crop.
The present invention can also be used to improve crop qualities such as good plant
growth, biotic and abiotic stress management, support in nutrient uptake by plant,
manage the root and shoot growth, increase branching, flowering, prevent flower
and fruit shedding etc. and other advantages familiar to a person skilled in the art.
It was thus noted that the composition of the present invention helps to improve not
only quantitative characteristic of the crop such as yield but also the qualitative
parameters such as number of tillers, panicle length etc. as compared to untreated
control.
Also, the compositions of the present invention are suitable for drip irrigation or
sprinkler irrigation in addition to other methods of applications of the agricultural
compositions. The composition is highly safe to the user and to the environment.
From the foregoing, it will be observed that numerous modifications and variations
can be effectuated without departing from the true spirit and scope of the novel
concepts of the present invention. It is to be understood that no limitation with
respect to the specific embodiments illustrated is intended or should be inferred
Amended Claims-Marked up Copy
Claims (17)
1. An agrochemical composition comprising: i. a complex formed with: a. at least one of elemental zinc or its salt thereof, b. at least one of eugenol or a source thereof; and ii. at least one agrochemical excipient; wherein the composition comprises particles in the size range of from 0.1 micron to 50 microns.
2. The agrochemical composition as claimed in claim 1, wherein the composition has a suspensibility of at least 30%.
3. The agrochemical composition as claimed in claim 1, wherein the complex is present in a concentration range of from 1-95% w/w of the total composition, preferably in the range of from 5- 95% w/w of the total composition.
4. The agrochemical composition as claimed in claim 1, wherein the composition is in the form of a solid or a liquid or a gel.
5. The agrochemical composition as claimed in claim 4, wherein the solid composition is in the form of water dispersible granules, broadcast granules, water disintegrable granules, wettable powder or micro granules.
6. The agrochemical composition as claimed in claim 5, wherein the water dispersible granules, water disintegrable granules, broadcast granules are in the size range of from 0.1 to 6 mm.
7. The agrochemical composition as claimed in claim 5, wherein the micro granules are in the size range of from 0.1 to 2.5 mm. Amended Claims-Marked up Copy
8. The agrochemical composition as claimed in claim 4, wherein the liquid composition is in the form of suspoemulsion, emulsion in water, oil dispersion, liquid suspension, aqueous suspension, suspension concentrate, emulsifiable concentrate, seed dressing or emulsions for seed treatment and combinations thereof
9. The agrochemical composition as claimed in claim 1, wherein the zinc salt comprises one or more of water soluble zinc salts, water insoluble zinc salts; and mixtures thereof.
10. The agrochemical composition as claimed in claim 9, wherein the water insoluble zinc salt comprises one or more of zinc oxide, zinc carbonate, zinc hydroxides, zinc stearate and mixtures thereof.
11. The agrochemical composition as claimed in claim 9, wherein the water soluble zinc salt comprises one or more of zinc acetate, zinc chloride, zinc nitrate, zinc sulfate, zinc bromide, sodium zincate, zinc iodide and mixtures thereof.
12. The agrochemical composition as claimed in claim 1, wherein the source of eugenol is one or more of essential oil, plant extract and mixtures thereof.
13. The agrochemical composition as claimed in claim 12, wherein the essential oil or plant extract includes one or more of clove, nutmeg, cinnamon, basil, bay leaf, ginger, celery, vanilla, lemon balm, dill, japnese star anise, cinnamomum, wormwood and mixtures thereof.
14. The agrochemical composition as claimed in claim 1, wherein the composition further comprises at least one of nutrients selected from macronutrients, micro nutrients; biostimulants; pesticidal actives; plant growth regulators; microbes; algae; bactereospores; fertilizer selected from nitrogen fertilizer, phosphorous, potassium fertilizers, sulfur fertilizers; salts or complexes or derivatives and mixtures thereof.
15. The agrochemical composition as claimed in claim 1, wherein the agrochemically acceptable excipient is selected from one or more of fillers or carriers or diluents, spreading agents, colorants, binders, buffers or pH adjusters or neutralizing agents, antifoaming agents or defoamers, anti-settling agents, water miscible solvents, penetrants, preservatives, ultraviolet absorbents, UV ray scattering agents, stabilizers, surfactants, dispersing agents, emulsifiers, wetting agents, structuring agents, disintegrating agents, thickeners, chelating or complexing or sequestering agents, viscosity modifiers, tackifiers, suspension aid, rheology modifiers, anti-settling agents, humectants, anti-freezing agent, sticking agents and mixtures thereof.
16. The agrochemical composition as claimed in claim 1, wherein the composition is at least one of a crop protection composition, a pesticide composition, a fungicide composition, a bactericide composition, a fertilizer composition, a nutrient composition, a crop strengthener composition.
17. A method of protecting the crop, improving its health and growth or enhancing the crop yield, the said method comprising treating at least one of a plant, crop, plant propagation material, locus or parts thereof, a seed, seedling or surrounding soil with the composition as claimed in claim 1.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN201721026745 | 2017-07-27 | ||
PCT/IB2018/055632 WO2019021250A1 (en) | 2017-07-27 | 2018-07-27 | Novel crop fortification, nutrition and crop protection composition |
PCT/IB2019/056402 WO2020021506A1 (en) | 2017-07-27 | 2019-07-26 | An agrochemical composition |
Publications (2)
Publication Number | Publication Date |
---|---|
NZ771810A NZ771810A (en) | 2021-11-26 |
NZ771810B2 true NZ771810B2 (en) | 2022-03-01 |
Family
ID=
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2019311391B2 (en) | An agrochemical composition | |
CA3104970C (en) | Novel agricultural composition | |
EP3810562B1 (en) | Novel crop nutrition and fortification composition | |
AU2021348415B2 (en) | Pesticidal composition comprising elemental sulphur and flupyradifurone | |
AU2021327950B2 (en) | Pesticidal composition comprising elemental sulphur and choline salt of pelargonic acid | |
NZ771810B2 (en) | An agrochemical composition | |
WO2021191915A1 (en) | Pesticidal composition comprising elemental sulphur and anthranilic diamide insecticide | |
AU2022289516B2 (en) | Novel pesticidal composition | |
AU2022331219B2 (en) | Novel pesticidal composition | |
WO2023047294A1 (en) | Novel pesticidal composition | |
WO2023223348A1 (en) | Novel pesticidal composition | |
NZ769951B2 (en) | Novel crop nutrition and fortification composition |