NZ713690B2 - Dispenser cap arrangement - Google Patents

Abstract

dispenser cap arrangement for enclosing a portion of a dispenser of a medicament. In particular, the present invention relates to a dispenser cap arrangement, a dispenser cap a dispenser cap closure device, a method of closing a dispenser, and a closure arrangement. The dispenser cap arrangement comprises a dispenser cap comprising a hollow body having a lower open end for engaging with a body portion of a dispenser, and an upper open end for receiving a cap closure device for closing the upper open end, the upper open end comprising an engageable portion; and a cap closure device, comprising: an upper cap closure portion for engaging with the upper open end of the dispenser cap to close the upper open end of the dispenser cap; a lower cap closure portion for engaging with the engageable portion to secure the cap closure device to the dispenser cap; and a bistable portion (111, 112, 113) connecting the upper cap portion and the lower cap closure portion, the bistable portion being switchable between a first stable form in which the bistable portion is extended, and a second stable form in which the bistable portion is collapsed, wherein, when the bistable portion is in the second stable form, the upper cap closure portion engages with the upper open end of the dispenser cap to close the dispenser cap. The lower closure portion comprises a plurality of protrusions (103) extending radially outwards having an upper surface for engaging with the engageable portion of the hollow body. A lower surface of the lower lid closure portion is engageable with a surface of an article to be enclosed. omprises a dispenser cap comprising a hollow body having a lower open end for engaging with a body portion of a dispenser, and an upper open end for receiving a cap closure device for closing the upper open end, the upper open end comprising an engageable portion; and a cap closure device, comprising: an upper cap closure portion for engaging with the upper open end of the dispenser cap to close the upper open end of the dispenser cap; a lower cap closure portion for engaging with the engageable portion to secure the cap closure device to the dispenser cap; and a bistable portion (111, 112, 113) connecting the upper cap portion and the lower cap closure portion, the bistable portion being switchable between a first stable form in which the bistable portion is extended, and a second stable form in which the bistable portion is collapsed, wherein, when the bistable portion is in the second stable form, the upper cap closure portion engages with the upper open end of the dispenser cap to close the dispenser cap. The lower closure portion comprises a plurality of protrusions (103) extending radially outwards having an upper surface for engaging with the engageable portion of the hollow body. A lower surface of the lower lid closure portion is engageable with a surface of an article to be enclosed.

Description

Dispenser Cap Arrangement FIELD OF THE INVENTION Thepresent invention relates to a dispenser cap arrangement for enclosing a portion of a dispenser of a medicament. In particular, the present ion relates to a dispenser closure device, a method of cap arrangement, a dispenser cap, a dispenser cap closing a dispenser, and a closure arrangement.

BACKQBQ: corms lNVENTlON In general, metered-dose inhalers (MDls) are devices for dispensing medicaments, e.g. in aerosol form, to the lungs. Broadly speaking dispensers such as MDls are comprised of two components: a container and a delivery device. The container holds the medication, e.g. dissolved or suspended in a propeliant under high pressure to maintain liquid phase. Additionally the container often comprises an al metering valve, which is designed to release a precisely ed, reproducible dose of medicament when the valve is actuated. The delivery device lly includes an actuator and a iece. The actuator, which can be triggered by the user, for example by inhalation or manual operation, typically interacts with the metering valve the container to induce release of a dose. The iece serves to direct the tion towards the user.

We have usly described a number of dispensers, see for e US 7,721,731.

However, it has been found that manufacturing tolerances mean that the length of a ner or substance source can vary from container to container. rmore, the length of the spout of the container may vary, too.

This can cause problems in dispenser devices wherein the aerosol can is stationary and another part is moved relative to the can to displace its valve and dispense medicament. Typically the other moving part can only move a certain distance (Le. a predetermined amount of travel) which means that it, for example a can or its valve is relatively the valve may not be fully displaced. As a result, a full dose of short, medicament may not be dispensed.

There have been different ches taken to overcoming this m. See, for example,‘W02003/0801 61 or W02007/029019.

In the above—mentioned previous approaches, the ser body and cap are a constant size and the canister is placed in the body at the same position in all dispensers. The variation in the resulting space between the end of the canister and the cap is taken by deformable materials placed atop the container. r, the above solutions do not always provide actory results, so we have iated need for an improved dispenser cap arrangement.

STATEMENT OF THE INVENTION The present ion therefore provides a dispenser cap arrangement for enclosing a portion of a dispenser of a medicament, the dispenser cap arrangement sing: a with a dispenser cap comprising a hollow body having a lower open end for engaging body portion of a dispenser, and an upper open end for receiving a cap closure device for closing the upper open end, the upper open end comprising an engageable portion; and a cap closure device, comprising: an upper cap closure portion for engaging with the upper open end of the dispenser cap to close the upper open end of the dispenser with the engageable portion to secure the cap; a lower cap closure portion for engaging and a le portion connecting the upper cap closure device to the dispenser cap; and lower cap closure cap closure portion the portion, the bistable portion being switchable between a first stable form in which the bistable portion is extended, and a second stable form in which the bistable portion: is collapsed, wherein,“ when the bistable portion is in the second stable form, the upper cap closure portion engages with the upper open end of the dispenser cap to close the dispenser cap.

The in combination with the closure device, provide a means of cap. enclosing a portion of a dispenser. Advantageousiy, the bistable n of the closure device that is switchable between two stable forms (extended and collapsed) enables the e device to be inserted and the cap closed when the closure device is in the desired position relative to the cap. Furthermore, the cap closure device, once in a stable form, requires a force to be applied to the upper closure portion to switch n the stable tOrms. As such, once in the collapsed form, the closure device is difficult to remove from the cap, thereby securing the closure device to the cap so that it cannot easily be removed. Furthermore, by using the above-mentioned cap closure device, a dispenser is able to be assembled where the medicament container of a dispenser can be fixed in the body in such a position that reliableand reproducible dosing can be achieved regardless of differences in the length of thespout and/or length of the container due to manufacturing tolerances. in embodiments of the dispenser cap arrangement, the bistable portion of the cap closure device comprises: a substantially rigid separator connected to the upper cap closure portion; and a resiliently deformable separator having first and second ends, the first end being connected to the substantially rigid separator via a resiliently deformable joint, and the second end being connected to the lower cap closure portion via a resiliently able joint, n the ently deformable separator is configured to resiliently deform upon application of a force to the upper cap closure portion and lower cap closure portion so as to permit a change of form of the ser cap closure device between the first stable form and second stable form. Such a configuration advantageously provides the cap closure device with the ability to be switched between the two stable forms.

Preferably, an angle defined n an outer surface of the substantially rigid separator and the resiliently deformable separator is acute when in the second stable form, and obtuse when in the first stable form. in further embodiments of the dispenser cap arrangement, the lower cap e portion comprises a plurality of protrusions extending radially outwards having an upper , surface for engaging with the engageable portion of the dispenser cap, and wherein a lower surface of the lower cap closure portion is engageable with a e of a medicament container in a dispenser. The plurality of sions extending from the lower cap e portion thus provide a means to secure the cap closure portion to the cap.

Preferably, the engageable portion of the dispenser cap comprises a ramped n, and wherein the ramped portion and the protrusions on the lower cap closure portion are configured such that on of the cap closure device causes the upper surface of the plurality of sions to ride along the ramped portion so as to draw the cap closure device further into the dispenser cap. Preferably, when the cap closure device is d, the riding of the upper surface of the protrusions along the ramped portion causes the lower surface of the lower cap closure portion to drive down onto a medicament ner in a dispenser.

By ing the ramped portions, the protrusions on the lower cap closure portion of the cap closure device may ride along the ramped portion and thus be drawn into the cap during rotation of the cap closure device. The position of the cap closure device relative to the cap may thus be adjusted prior to the bistable n being switched from the ed to the collapsed forms. As such, tolerances in the length of the container or the container spout in the dispenser may be accounted for prior to final assembly of the dispenser. ln embodiments with the ramped portion, the ramped portion comprises a plurality of ramped portions around the circumference of a lip of the dispenser cap, the plurality of ramped portions equalling the number of ity oi protrusions on the lower cap portion of the cap closure device. Preferably, the ramped portions are separated from one and other by a gap having a width that is r than or equal to the width of a sion on the lower cap closure portion. in further embodiments, of the dispenser cap arrangement, an Upper surface of the dispenser cap comprises a limiting means for preventing rotation of the cap closure device when in the second stable form. Preferably, the limiting means ses a plurality of teeth located on an upper surface of the dispenser cap, and wherein the dispenser cap closure device comprises a plurality of protrusions on a lower surface of the upper cap closure portion, the teeth and protrusions being configured to engage with one another so as to prevent on of the cap closure device when in the second stable form.

By providing a limiting means, further rotation of the cap closure device, once in the collapsed state, may be prevented. As such, the cap closure device is prevented from rotating further into, or out of the cap. The cap closure device is thus secured in place. in some embodiments, the dispenser cap may comprise one or more protrusions in the upper open end of the dispenser cap, the one or more protrusions being arranged engage with a correspondingly shaped recess in the upper cap closure portion when the ser cap is closed by the dispenser closure device. Such an arrangement helps retain the dispenser cap closure device in place once inserted into the end of the dispenser cap.

The present invention aiso provides a dispenser cap closure device for closing an end of a dispenser cap of a medicament dispenser, the cap closure device sing: an of a dispenser cap to upper cap e portion for engaging with an upper open end close an open end of a dispenser cap; a lower cap closure portion for engaging with a an engageable portion of the upper open end of a ser cap to secure the cap closure device to a dispenser cap; and a bistable portion connecting the upper cap e portion and the lower cap closure portion, the bistable portion being switchable n a first stable form in which the bistable portion is extended, and a second stable form in which the bistable portion is collapsed, wherein, when in the second stable form, the upper cap ciosure portion and lower cap ciosure portion are brought closer together.

The dispenser cap closure device advantageously comprises the bistable portion, which enables the cap closure device to be switched between two stable forms.

Furthermore, by using the above-mentioned cap closure , a dispenser is able to 2O be assembied where the medicament container of a dispenser can be fixed in the body in such a position that le and reproducible dosing can be achieved regardless of differences in the length of the spout and/or length of the container due to manufacturing toierances.

In embodiments of the dispenser cap e device, the bistable portion comprises: a substantially rigid separator connected to the upper cap portion; and a resiliently deformable separator having first and second ends, the first end being ted to the substantially rigid separator via a resiliently deformable joint, and the second end being connected to the lower cap e. portion via a resiliently deformabie joint, n the resiliently deformable separator is configured to resiliently deform upon application of an opposing force between the upper cap ciosure portion and lower cap closure n so as to permit a change of form of the dispenser cap closure device between the first stable form and second stabie form. Such a configuration advantageousiy provides the cap closure device with the ability to be switched between the two stable forms.

Preferably, surface the an angle defined between an outer of substantially rigid separator and the resiliently deformable separator is acute when in the second stable form. and obtuse when in the first stable form.

In further embodiments of the dispenser cap closure , the lower cap e outwards having an upper portion comprises a ity of protrusions extending ly surface for engaging with an engageable portion of a dispenser cap, and wherein a With a surface of a lower surface of the lower cap closure portion is engageable the are substantially medicament container in a dispenser. ably, sions equally-spaced circumferentially around the lower cap closure n. the dispenser cap closure In some embodiments of the dispenser cap closure device, of the upper cap closure device comprises a plurality of protrusions on a lower surface portion for engaging with correspondingly-spaced teeth on a dispenser cap for state. preventing rotation of the ser cap closure device when in the collapsed in the upper in further embodiments, the upper cap e portion comprises a recess e portion that is arranged to engage with a correspondingly shaped retain protrusion in an upper open end of a dispenser cap. Such an arrangement helps the dispenser cap closure device in place once inserted into the end of the dispenser cap.

The present invention also provides a dispenser cap for enclosing a portion of a dispenser of a medicament, the dispenser‘cap comprising: a hollow body having a lower open end for engaging with a body portion of a dispenser, and an upper open end for receiving a dispenser cap closure device for closing the upper open end, wherein "the upper open and comprises an engageable portion for engaging with a of the hollow body. For dispenser cap closure device for closing the upper open end above. e, the ser cap could be the dispenser cap as described closure device may be By using the above-mentioned dispenser cap. a dispenser cap medicament container of used such that a dispenser is able to be assembled where the a dispenser can be fixed in the body in such a position that reliable and reproducible dosing can be achieved regardless of differences in the length of the spout and/or length of the container due to manufacturing tolerances. in ments of the dispenser cap, the engageable portion comprises a plurality of ramped portions around the circumference of the dispenser cap. Preferably, each of the ramped portions is separated by a gap. in some embodiments, the dispenser cap has an upper surface of the dispenser cap that comprises a limiting means for preventing rotation of a dispenser cap closure device when engaged with the dispenser cap. in such embodiments, the limiting means comprises a piurality of teeth d on the upper open end of the dispenser cap, the teeth for ng with one or more protrusions on a dispenser cap closure device so as to prevent rotation of a dispenser cap closure device when engaged. in further embodiments, the dispenser cap may comprise one or more sions in the upper open end of the dispenser cap, the one or more protrusions being arranged to engage with a correspondingly shaped recess in an upper cap closure portion of a ser cap closure device for closing the dispenser cap. Such an arrangement helps retain the dispenser cap e device in ptace once inserted into the end. of the dispenser cap.

The present invention also provides a dispenser for dispensing a dose of medicament from a substance source, the dispenser comprising: a body for receiving a substance is dispensable; a source, the body having a iece through which a medicament substance source comprising a container containing a medicament to be dispensed; a dispenser cap arrangement as described above, wherein the dispenser cap arrangement is coupled to the body for ing the substance source. Such a dispenser may thus be closed using the cap closure device comprising the bistable n, such that it may not be opened by a user or tampered with once closed.

By using the above-mentioned cap closure , the dispenser can be led where the medicament container can be fixed in the body in such a position that reliable and reproducible dosing can be achieved regardless of differences in the length of the spout and/or length of the container due to manufacturing tolerances.

In embodiments oi the dispenser, the substance source is a pressurised metered-dose inhaler (pMDl).

In further embodiments of the ser, the dispenser further ses a dose counter for ting a number of actuations of the dispenser corresponding to a number of doses dispensed from the substance or, or a number of doses remaining Substance Advantageously, the dose counter enables the user to the source. determine how many doses remain in the dispenser so that the user knows when to obtain a replacement dispenser.

The present ion further provides a method of closing a dispenser for sing a dose of medicament from a substance source, the dispenser comprising: a body substance the body having a mouthpiece h which receiving source, a medicament is dispensable; a nce source comprising a container containing a medicament to be dispensed; and a dispenser cap arrangement for coupling to the 15 body for enclosing the substance source, the dispenser cap arrangement comprising a dispenser cap and dispenser cap closure device, the method sing the steps inserting the substance source into the body of the dispenser and affixing the dispenser cap to the body of the dispenser, or vice versa; inserting the dispenser cap closure , device into an upper open end of the dispenser cap; applying a force to the dispenser of the ser cap e device from cap closure device to switch a bistable portion a first stable form in which the bistable portion is extended, and a second stable form in which the bistable portion is collapsed, wherein, when the bistable portion is in the second stable form, the upper cap closure portion engages with the upper open end the dispenser cap to close the dispenser cap. The bistable portion of the cap closure device thus enables the dispenser to be closed. assembled By using the above-mentioned cap closure device, a dispenser is able to be where the medicament container of a dispenser can be fixed in the body in such a position that reliable and reproducible dosing can be achieved regardless of ences in the length of the spout and/or length of the container due to manufacturing tolerances.

In embodiments of the method, the method further comprises ng the dispenser that a closure device prior to the step of applying a force, such plurality of protrusions extending radially outwardly from a lower cap closure n of the dispenser cap closure device engage with a ramped portion on a lower lip of the upper is secured to the cap so open end of the dispenser cap. Thus the cap e portion that it cannot be removed.

The present invention also provides a closure arrangement for enclosing an e, the closure arrangement comprising: a hollow body for enclosing an article, having an for receiving a closure device for closing the upper open end, the upper open end closure device, comprising: upper open end comprising an engageable portionj and a the hollow body to an upper closure portion for engaging with the upper open end of close the upper open end of the hollow body; a lower closure n for engaging with the engageable portion to secure the closure device to the hollow body; and a bistable n connecting the upper closure portion and the tower closure portion, the bistable in which the bistable portion is _ portion being switchable between a first stable form extended, and a second stable form in which the bistable n is collapsed, wherein, when the bistable portion is in the second stable form, the upper closure portion the upper open end of the s with the upper open end of the hollow body to close hollow body such that an article in the hollow body is enclosed.

The hollow body, in combination with the closure device, provide a means of, enclosing that is switchable an article. Advantageously, the bistabte portion of the closure device n two stable forms ded and collapsed) enables the closure device to be inserted and hollow body closed when the closure device is in the desired position relative to the hollow body. Furthermore, the closure device, once in a stable form, requires a force to be applied between the upper and lower closure portions to switch between the stable forms. As such, once in the collapsed form, the closure device is difficult to remove from the hollow body, thereby securing the closure device to the hollow body so that it cannot easily be removed. Furthermore, by using the above- mentioned closure device, an article may be assembled where the a device of an article can be fixed in the body in such a position that reliable and ucible operation may be achieved regardless of differences in the length of the article due to manufacturing tolerances. in embodiments of the closure arrangement, the bistable portion of the e device comprises: a ntially rigid separator connected to the upper closure portion; and a resiliently deformable separator having first and second ends, the first end being and the connected to the substantially rigid separator via a resiliently deformable joint, second end being connected to the lower cap closure portion via a resiliently deformable joint, wherein the resiliently deformable separator is configured to resiliently deform upon application of a force to the upper closure portion so as to permit a change of form of the closure device n the first stable form and second stable between the two form. This configuration enables the bistable portion to be switchable stable forms. of the Preferably, an angle defined between an outer surface substantially rigid in the second stable separator and the resilientlyrdeformable separator is acute when form, and obtuse when in the first stable form. in some embodiments of the e arrangement, the lower closure portion comprises e for a plurality of protrusions extending radially outwards having an upper lower e engaging with the engageabie portion of the hollow body, and wherein a article to be of the lower lid closure portion is engageable with a surface of an enclosed. The piurality of protrusions extending from the lower e portion thus provide a means to secure the closure portion to the hollow body.

Preferably, the engageable portion comprises a ramped portion, and wherein such that ramped portion and sions on the lower closure portion are configured rotation of the closure device causes the upper surface of the plurality of protrusions into the hollow ride along the ramped portion so as to draw the closure device further body. Preferably, when the closure device is rotated, the riding of the upper e of lower closure the protrusions along the ramped portion causes the lower surface of the portion to drive down onto an article to be enclosed. of the By providing the ramped ns, the protrusions on the lower closure portion 3O closure device may ride along the ramped portion and thus be drawn into the hollow relative to body during rotation of the closure . The position of the closure device from the hollow body may thus be adjusted prior to the bistable portion being ed the ed to the collapsed form.

In embodiments of the closure arrangement, the ramped portion comprises a plurality the plurality of of ramped portions around the circumference of a lip of the hollow body, lid n ramped ns equalling the number of plurality of protrusions on the lower of the lid e device. Preferably, the ramped ns are separated from one another by a gap having a width that is greater than or equal to the width of a protrusion on the lower closure portion. r embodiments of the closure arrangement, an upper surface of the hollow in when in body comprises a limiting means for preventing rotation of the closure device the second stable form. once in the By providing a limiting means, further rotation of the closure device, collapsed state, may be prevented. As such, the closure device is prevented from rotating further into, or out of the hollow body. The e device is thus secured place.

Preferably, the limiting means comprises a pluraiity of teeth located on an upper surface of the hollow body, and wherein the closure device comprises a plurality protrusions on a lower surface of the Upper closure portion, the teeth and protrusions of the closure 2O being configured to engage with one another so as to prevent rotation device when in the second stable form. in the in some embodiments, the hollow body may se one or more protrusions upper open end of the hollow body, the one or more protrusions being ed to in the upper closure portion when the engage with a correspondingly shaped recess hollow body is closed by the closure device. Such an arrangement helps retain the closure device in place once inserted into the end of the hollow body.

The present invention also provides a closure device for sealing an opening in a body comprising: a first portion for sealing an g; a second portion, and a connecting portion ting the first and second portions, the second portion being adapted to to switch from a first secure the device to a body, the connecting portion being adapted configuration to a second configuration upon application of a force to the device, wherein in the first configuration the device can be appiied to and secured to a body and in the second configuration the first portion will seal an opening in the body.

By using the above-mentioned closure device, a dispenser is able to be assembled where the medicament container of a dispenser can be fixed in the body in such a position that retiable and reproducible dosing can be achieved regardless of differences in the length of the spout and/or length of the” container due to manufacturing tolerances.

Preferably, in the second configuration the first portion and the second portion are closer to each other than in the first configuration. further provides an enclosure arrangement for ing an The present invention e comprising: a hollow body for receiving an article and having an upper open end, said open end, wherein the hollow a closure device, as described above, for sealing body and the closure device have respective engageabie portions for securing the body and device together, and in the second uration the second portion of the closure device is adapted to contact an article in the body and the first portion of the closure device is adapted to seal the opening in the upper end of the body.

Preferably, the able portions are adapted to secure the hollow body and closure device together upon ve rotation of the body and device.

LIST OF FIGURES The present invention will now be described, by way of example only, and with reference to the drawings, in which: is a perspective view of a dispenser in a closed configuration; is a similar view of the dispenser in open configuration; is an ed view of a prior version of the dispenser; shows an upper portion of a preferred main body part of the ser; is an underside view of a preferred dispenser cap; is an upper—end view of the dispenser cap of is a ctive view of the dispenser cap of ; is a rough view of the dispenser cap of through axis X-X of is a preferred dispenser cap ciosure device; e device of is a rough View along the X-X line of the dispenser cap extended state; a is the dispenser cap closure device of in an b is the ser cap closure device of in a collapsed state; FIGs. 11a to 11f show a sequence of steps of the dispenser cap assembly; shows an alternative closure device.

DETAILED PTION OF THE PREFERRED EMBODIMENTS 1 to 3 are taken‘from our Referring first to FIGS. 1 to 4 of the drawings (of which figures 7,721,731), the dispenser has a body 1 with corresponding granted patent US a is formed as an mouthpiece 2 and a pivoted mouthpiece cover 3. The mouthpiece 6 ugh the skilled aperture 4 in a separate body part 5 clipped to a main body part reader would appreciate that this formation could be made using a single-moulded the mouthpiece part has piece). The main part 6 has upper and lower formations and formations which engage when the mouthpiece part is upper and lower complementary has a cutaway slid from below to engage with the main part. The separate body part with respect to the main body part 6, to define an air inlet 12 exposed by the cover 3 Immediately when this is opened. A medicament can C sits inside the body part 6. within the air inlet 12 is a guard 13 against fingers. between the two The cover 3 is pivoted about an axis A low in the body 6 at the joint shaft. The shaft carries a body parts. lntegrally moulded with the cover 3 is a C n with two fingers, at central cam arrangement 23, comprising two cam lobes, er one of a pair of discs, between which one and an outer one. The latter is integral with is bearingly supported by part circular ls in flanges are the cam lobes, the shaft integrally moulded within the main body part 6.

The body parts 5,6. and the cover 3 (with the shaft and cam arrangement) in can be described embodiments are of moulded polypropylene al, whereby they fitted together with a modicum of flexure.

The can C is held in an opening 31 at the upper end of the main body part 6, where the C. A body part extends completely around a valve crimp portion CP of the can surround and encase the dispenser cap (not shown) couples to the main body part 6 to is coupled to the main body part 6 upper d end of the can C. The dispenser cap be used so long as for example by means of protrusions 51. Other fixing means may that they do not come the main body part and dispenser cap are engaged together so apart easily.

A junction member 41 is slidably accommodated in the body. The junction member also is of moulded polypropylene. Centrally, the junction member has a socket for an outlet stem 8 of the can C. The socket is continued by a passage, which has a thin which is coupled to wall, kinkable portion and a nozzle end (moveable outlet member), a medicament sed from the can a nozzle. When the kinkable portion is unkinked, stem into the passage is released through the nozzle and into a mouthpiece of the dispenser. the cam 23 to in ion, rotation of the mouthpiece cover 3 about the axis A causes movement of impart an upward force on the junction member 41. The resulting upward which ses a dose the junction member 41 es the outlet stem 8 of the can, The dispenser is now of ment into the junction member and into the kink valve. primed and ready with a dose of medicament. the air inlet 12 Upon inhalation by a user through the mouthpiece 5, air drawn through member 41, impresses on the flap 61 causing the flap to move and release the junction which allows the kink valve to un-kink (due to the resilience of the passageway making of the medicament in the valve) to release the dose up the kink valve, and the pressure the close of medicament into the mouthpiece. Continued inhalation by the user causes the user. of medicament to be drawn out of the mouthpiece and delivered to After inhalation, the user closes the mouthpiece cover, and the junction member and flap Gt return to their initial, med, positions. other As discussed above, tolerances in the length of the can and its spout and in 30 components with which the can is in contact mean that the can is not always seated in in figures 1 to 4, the same position relative to the body and a dispenser cap (not shown main body part but the cap surrounds the upper portion of the can and is coupled to the 6). Since the can C is ably seated so that the movement of the junction member is able to effect dispensing of a precise dose of medicament, there is need of a device to take up the variabie height of the can 0 and/or its spout relative to the body.

We will now describe a dispenser cap arrangement, dispenser cap closure device and dispenser cap that has been designed to take up these tolerances and to allow the dispenser to work as intended.

With nce to figures 5 to 7, a dispenser cap 71 has a plurality of openings 73 shaped and configured to engage with the protrusions 51 on the main body part 6 so that the dispenser cap and main body part remain affixed to one another. The lower open end 72 (the dispenser cap is shown upside down in figure 5) is shaped and . dimensioned to receive the portion of the can that extends from the main body part when mounted in the main body part. The ser cap may also be shaped and ioned to e a counter mechanism between the dispenser cap and the can.

Before assembly with the dispenser cap closure device, the dispenser cap has an open upper end 74.

A plurality of teeth 81 is provided along an upper part of the dispenser cap. These teeth are configured to engage with the dispenser cap closure device to prevent rotation once the latter is in the correct position. Preferably, the teeth are provided at least partially around the circumference of the upper part of the dispenser cap. This will be described in more detail below. in preferred embodiments, there are three d ns around the ference of the upper part of the dispenser cap, with gaps 75 between each section. Each toothed section has a lower ramped surface 82. Again, this wiil be described in more detail with reference to the dispenser cap closure device.

One or more protrusions 91 may also be provided along an upper part of the dispenser of the cap 71, which are arranged to engage with a correspondingly shaped portion dispenser cap closure device 100 to help retain the dispenser cap closure device in 3O place once inserted into the end of the dispenser cap. in preferred embodiments, there is one protrusion 91 for each gap 75.

We will now describe a cap closure device (or ‘bung’) that works with the above- bed dispenser cap 71 to close the end of the ser, and take up any tolerances in the length of the container.

With reference to figures 8 to 10, the dispenser cap closure device 100 comprises an 102. The upper 101 and upper cap ciosure portion 101 and a lower cap closure portion 113. tower 102 cap closure portions are ted by a bistable portion 110, 111, 112, portion 101 comprises a ity of radial extending ribs The upper cap closure or ridges 104 located on an underside or lower surface of the upper cap closure portion 101. The upper cap closure portion 101 is configured to engage with the upper open end 74 of the dispenser cap 71 and to close the upper open end 74 when the two are engaged. sions in the form of radial extending ribs or ridges 104 are configured to engage with the teeth 81 on the upper lip of the dispenser cap 71 to prevent rotation of the dispenser cap closure device 100 when engaged with the dispenser cap Furthermore, ridge 121 in the ferential edge of the upper cap closure portion 101 is configured to engage with the protrusions 91 in the dispenser cap 71 to help retain the dispenser cap ciosure device in place once inserted into the end of the dispenser cap.

The lower cap closure portion 102 has a lower surface that is ured to contact end of a canister C in the dispenser when the dispenser cap closure device is d with the dispenser cap. A piuraiity of protrusions 103 are also located radially around the lower cap closure portion. The protrusions 103 are configured to engage with ramped n 82 of the dispenser cap 71 as will be described below.

The bistable portion 110, 111, 112, 113 cemprises a substantially rigid separator 110 and a resiliently deformable separator 111. The substantially rigid separator 110 is fixed to or integral with the upper cap closure portion 101. The resiliently able tor 111 is connected to the substantially rigid separator 110 at one end by means of a resiliently deformable joint 112, and the resiiiently deformabie tor 111 is connected to the tower cap closure portion 102 at the other end by means of a resiiiently deformable joint 113.

The structure of the resiliently able separator 111 and resiliently deformable switch or joints 112, 113 are configured to enable the dispenser cap ciosure device to invert between a first stable form in which the bistable portion is extended (shown F101. 10a) and a second stable form in which the bistable portion is collapsed (shown in b). The upper 101 and lower 102 portions of the dispenser cap closure device are brought closer together in the second stable form (Le. collapsed state). As can be seen in Fle. 10a and 10b, an angle between the outer surface of the substantially rigid separator 110 and the outer e of the resiliently deformable separator 111 is generally obtuse when the cap closure device is in the first stable form, and generally acute when the cap closure device is in the second stable form. The purpose of these two stable forms will be explained below.

The structure of the resiliently deformable separator 111 and resiliently able joints 112, 113 are configured such that the bistable portion, once in one of the two stable forms, remains in that stable form. A force applied to the upper 101 cap e portion is required to switch the bistable portion from the first to the second stable form. Effectively, the force required to switch the bistable portion is proportional to the force required to deform the resiliently deformable separator 111 sufficiently such that the resiliently deformable separator 111 may pass through a substantially horizontal position (for example see figures 9 and 10), which des with the shortest distance between the resiliently deformable joints 1 12, 1 13.

The dispenser cap assembly comprising the dispenser cap 71 and dispenser cap e device 100 will now be described with reference to Fle. 11a to 11f.

In a, the dispenser cap 71 is affixed to the main body part 6 of the dispenser (not shown). The upper open end of the dispenser cap is configured to receive the canister or ner C, which is inserted h the upper opening and the spout S is seated in the junction member 41 in the body (not shown). atively, the container C may be d before the dispenser cap 71 is affixed to the main body part 6.

In Fle. 11b, 11c and 11d (once the canister C is seated correctly), the dispenser cap closure device 100 (in its first stable form i.e. extended) is lowered into the upper open end of the dispenser cap 71 until the lower cap closure portion 102 is seated on the end of the canister C. In order for this to happen, each of the protrusions 103 on the lower portion 102 is aligned with a corresponding gap 75 n the toothed sections or the upper open end of the cap, which allows the cap closure device 100 to drop through to the canister C. in FiG 11s, the cap closure device 100 is rotated. in doing so, protrusions 103 engage 81. Each of the ramped with the ramped surface 82 under each of the toothed ns in one portions 82 are configured such that rotation of the cap closure device 100 direction drives the protrusions (and therefore the cap closure ) downwards which draws the cap closure device 100 further into the towards the canister C dispenser cap 71. Furthermore this downward drive pushes the lower cap closure initial portion 102 against the end of the canister C. Continued rotation beyond an and the end of the canister will contact between the protrusion 103, ramped portion 82 the canister. apply a positive force in a longitudinal axis of the dispenser against 100 is dependent upon the The amount of rotation of the dispenser cap closure device length of the er and/or its spout (i.e. the nces that are being d), and whether or not a positive pressure on the canister is desirable. During assembly, the amount of rotation can be determined in advance of the dispenser cap closure device of the canister 100being inserted (for example by measuring the height of the end be configured to turn the cap relative to the body), and the ly machinery could that the slope of the closure device a specific number of degrees of rotation (assuming could be used ramped portion 81 is known). Alternatively, a force measuring device the cap closure device 100 during assembiy to e a back force registering on in torque when it is being rotated (or an increase required to turn the cap ciosure rotation when a ered force device), with the machine being configured to stop reaches a threshold or desired level. in HQ. 111, and once the desired rotation of the cap e device 100 has been is pushed down towards the d, the upper portion 101 of the cap closure device canister such that is switches from the first stabie form (i.e. extended) to the second stable form (i.e. collapsed). In the second stable form (as shown), radially extending ribs or ridges 104 on the underside of the upper portion 101 engage with the teeth 71. Such engagement between the portions 81 on the upper end of the dispenser cap ribs or ridges 104 and teeth portions 81 prevent further rotation (in either ion) of closure device 100. Furthermore, protrusions 91 in the dispenser cap 71 the cap portion retain the engage with the ridge 121 in the upper cap closure 101 to help dispenser cap ciosure device in place once inserted into the end of the dispenser cap. the cap closure device Since rised containers C generally have concave ends, 100 may extend below the original level of the lower portion 102 into the concave portion of such ners. it will be noted that, since a force is required to deform the resiliently deformable separator 111 to overcome the horizontal position as described above (and ore switch the bistable portion from the second to the first stable form), the dispenser cap closure device 100 is prevented from g of its own accord. As such, once the dispenser cap closure device is in the second stable form, it is very difficult to undo or remove the device, which increases safety and security of the dispenser, since it ’ makes it difficult for the user to tamper or take the dispenser apart.

In preferred embodiments, the dispenser cap 71 is transparent so that a counter can be read from beneath the surface. Alternatively, a transparent portion defining a window 71 is made from may be provided on the dispenser cap. Preferably, the dispenser cap polypropylene (for example R7051 -1 ON).

In preferred embodiments, the ser cap closure device 100 is made from polypropylene (for example ELTEX ZOOCA25). in an alternative embodiment of the closure device, the closure device works in the opposite, way to the ways described above i.e. the e device engages in the extended form rather than the contracted form.

Figure 12 illustrates the alternative closure device. The lower cap closure portion 102’ 103‘ engages with the dispenser cap 71’ as described above is. with the sions riding on the lower surface of a ramped portion, and the lower cap closure portion 102' ting a container (not shown) in the dispenser. The cap closure device is rotated or screwed into the correct position (to allow for the variation in height of the container) as above.

A substantially rigid separator 110’ tes the lower closure portion 102’ from the upper closure portion 101, which comprises a resiliently deformable section 120. The figure shows the closure device in the first, collapsed, form. Once the closure device is in place, a force may be applied to the resiliently deformable section 120, which causes the section to switch from the first, collapsed, stable form to a second, extended, stable form. in the extended form, the length of the upper e portion is extended such 71' to close the upper that the upper closure n engages with the dispenser cap open end of the dispenser cap. protrusions may be located on a surface cf the As with the previous embodiments, with correspondingly-shaped teeth located on the upper closure portion 101’ to engage device when engaged dispenser cap 71‘ to prevent further rotation of the cap closure with the dispenser cap.

Whilst we have described the invention in the t of a dispenser cap closure arrangement, or the dispenser cap closure device, we also envisage uses for the device articles other than with closure arrangement and closure on medicament dispensers. store an article, For example, the closure arrangement could be adapted to enclose or in such uses, the for example to close a container into which es may be placed. the teeth 81 and container could be d to receive the closure device by ing ramped portions 82 at an upper open end of' the container to engage with the corresponding features of the closure device (as described above with nce to 2O dispenser).

Since the closure device in such an alternative usage might not come into contact with a body such as a medicament container (to provide a suitable abutment surface to enable the bistable portion to be switched from the first stable form to the second stable form), an alternative could be to provide a surface (for e a protruding or which the lower raised surface on an inner circumferential surface of the container) to portion of the closure device could abut to enable the bistable portion to be switched. close the container Furthermore, the surface could be configured to provide a seal to when the closure device is in place and in the second (Le. collapsed) stable form (Le. when the lower closure portion of the closure device abuts the protruding e). and the lower portion In some embodiments, the seal between the ding surface seal between of the closure device could be ed to provide a fluid and/or ght the inside and outside of the container. in such embodiments, the container could at a higher therefore be used to contain liquids and/or gasses at atmospheric pressure, pressure (for e carbonated drinks, sparkling wines and the like) or at a d pressure (for example, vacuum sealing).

Articles stored in such a ner at atmospheric, or reduced atmospheric air pressures, would not influence the cap closure device, since the bistable portion retains the e device in the second (collapsed) stable form where the teeth in the container are engaged with the ridges or fingers 104 on the closure device.

If the internal pressure of the ner is greater than atmospheric pressure, then the closwe device may need to be ed in order to remain in the collapsed configured when the closure arrangement is closed. In the above-described embodiments, the flay closure device has an open lower end exposing a portion of the bistabte n to the contents of the container being enclosed. if the internal pressure of the sealed container is sufficient enough to overcome the force required to switch the bistable portion from the collapsed to the extended positions, the closdre device would not work.

However, a modification to overcome this problem could be to provide a sufficiently rigid surface below the bistable portion on the lower closure portion to take the force of the pressure of the container, and prevent that pressure from ncing the le portion. Such a surface could be in line with the lower closure portion, or could extend below the lower closure portion.

The closure device may also be adapted to be openable by providing a handle attached to the upper closure portion in order to allow the user to pull the upper closure portion away from the container (thus switching the bistable n back to the first, extended form) and thus unscrew the closure device from the lid of the container. in order to make this type of e tamper resistant, or child proof, the handle could be removable, for example using a screw fixing, or a slide mechanism to attach the handle to the closure device.

We therefore envisage that the closure arrangement may be provided on items such as bottles for ning liquids, containers for containing artictes and the like.

While the invention has been exemplified by the above ption of specific be considered by the reader embodiments, and uses thereof, the foregoing should not which is defined in the appended claims. as a limitation on the scope of the invention, 1001761811

Claims (14)

CLAIMS :

1. A closure arrangement for enclosing an article, the closure arrangement comprising: a hollow body for enclosing an article, having an upper open end for receiving a closure device for closing the upper open end, the upper open end comprising an engageable portion; and a closure device, comprising: an upper closure portion for engaging with the upper open end of the 1O hollow body to close the upper open end of the hollow body; a lower closure portion for engaging with the engageable portion to secure the closure device to the hollow body; and a bistable portion connecting the upper closure portion and the lower closure n, the bistable n being switchable between a first stable form 15 in which the bistable n is extended, and a second stable form in which the le portion is collapsed, wherein, when the bistable portion is in the second stable form, the upper closure n engages with the upper open end of the hollow body to close the upper open end of the hollow body such that an article in the hollow body is enclosed; and 20 wherein the lower e portion comprises a plurality of protrusions extending radially outwards having an upper surface for engaging with the engageable portion of the hollow body, and wherein a lower e of the lower lid closure portion is able with a surface of an article to be enclosed. 25

2. A closure arrangement according to claim 1, wherein the bistable portion of the closure device comprises: a substantially rigid separator ted to the upper closure portion; and a resiliently deformable separator having first and second ends, the first end being connected to the substantially rigid separator via a resiliently deformable joint, 30 and the second end being connected to the lower cap closure portion via a resiliently deformable joint, wherein the resiliently deformable separator is configured to ently deform upon application of a force to the upper closure portion so as to permit a change of form of the closure device between the first stable form and second stable form. 1001761811

3. A closure ement according to claim 2, wherein an angle defined between an outer surface of the substantially rigid tor and the resiliently deformable separator is acute when in the second stable form, and obtuse when in the first stable form.

4. A closure ement according to any one of claims 1 to 3, wherein the able portion comprises a ramped portion, and wherein the ramped portion and protrusions on the lower closure portion are configured such that rotation of the closure device causes the upper surface of the plurality of protrusions to ride along the ramped 1O portion so as to draw the closure device r into the hollow body.

5. A closure arrangement according to claim 4, wherein, when the closure device is rotated, the riding of the upper surface of the protrusions along the ramped portion causes the lower surface of the lower e portion to drive down onto an e to be 15 enclosed.

6. A closure arrangement ing to claim 4 or 5, wherein the ramped portion comprises a plurality of ramped portions around the circumference of a lip of the hollow body, the plurality of ramped portions ing the number of plurality of protrusions on 20 the lower lid portion of the lid closure device.

7. A closure arrangement according to claim 6, wherein the ramped portions are separated from one another by a gap having a width that is greater than or equal to the width of a protrusion on the lower closure portion.

8. A closure arrangement according to any one of claims 1 to 7, wherein an upper surface of the hollow body comprises a limiting means for preventing rotation of the closure device when in the second stable form. 30

9. A closure arrangement according to claim 8, wherein the ng means comprises a plurality of teeth located on an upper surface of the hollow body, and wherein the closure device comprises a plurality of protrusions on a lower surface of the upper closure portion, the teeth and protrusions being configured to engage with one another so as to prevent rotation of the closure device when in the second stable 35 form. 1001761811

10. A closure arrangement according to any one of claims 1 to 9, wherein the hollow body comprises one or more protrusions in an upper open end of the hollow body, the one or more protrusions being arranged to engage with a correspondingly shaped recess in the upper closure portion when the hollow body is closed by the e device.

11. A closure device for sealing an opening in a hollow body comprising: a first portion for sealing an opening; 1O a second portion, and a bistable connecting portion connecting the first and second portions, the second portion being adapted to secure the device to a body, the ting portion being adapted to switch from a first configuration to a second uration upon application of a force to the device, 15 wherein the second portion comprises a plurality of protrusions extending radially outwards having an upper surface for ng with the engageable portion of the hollow body, and wherein a lower surface of the second portion is engageable with a e of an article to be ed by the hollow body; and wherein in the first configuration the device can be applied to and secured to the hollow 20 body and in the second uration the first portion will seal an opening in the hollow body.

12. A device according to claim 11, wherein in the second configuration the first portion and the second portion are closer to each other than in the first configuration.

13. An enclosure ement for ing an article comprising: a hollow body for receiving an article and having an upper open end; a closure device according to claim 11 or 12 for sealing said open end, wherein the hollow body and the closure device have respective engageable portions 30 for securing the body and device together, and in the second configuration the second portion of the closure device is adapted to contact an article in the body and the first portion of the closure device is adapted to seal the opening in the upper end of the body. 1001761811

14. An enclosure arrangement according to claim 13, wherein the able portions are adapted to secure the hollow body and closure device together upon relative rotation of the body and device.