NZ623384A - Antimicrobial compounds and methods of making and using the same - Google Patents

Antimicrobial compounds and methods of making and using the same

Info

Publication number
NZ623384A
NZ623384A NZ623384A NZ62338410A NZ623384A NZ 623384 A NZ623384 A NZ 623384A NZ 623384 A NZ623384 A NZ 623384A NZ 62338410 A NZ62338410 A NZ 62338410A NZ 623384 A NZ623384 A NZ 623384A
Authority
NZ
New Zealand
Prior art keywords
making
methods
compounds
same
antimicrobial compounds
Prior art date
Application number
NZ623384A
Inventor
Ashoke Bhattacharjee
Marco Devivo
Yanming Du
Sandra Sinishtaj
Hardwin O’Dowd
Yuanqing Tang
Erin M Duffy
Brian T Wimberly
Original Assignee
Melinta Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Melinta Therapeutics Inc filed Critical Melinta Therapeutics Inc
Priority to NZ713357A priority Critical patent/NZ713357A/en
Priority claimed from NZ599290A external-priority patent/NZ599290A/en
Publication of NZ623384A publication Critical patent/NZ623384A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Vascular Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Materials For Medical Uses (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The present disclosure relates generally to the field of antimicrobial Pyrimidinone and other heterocyclic compounds and to methods of making and using them. These compounds are useful for treating, preventing, and reducing the risk of microbial infections in humans and animals. Compounds of the invention include: 1-(S-{ 4-[(3-Amino-propylamino)-methyl]-phenyl} -4-oxo-1,4-dihydro-pyrimidin-2-yl)-3-(2-trifluoromethoxy-phenyl)-urea
NZ623384A 2009-10-16 2010-10-15 Antimicrobial compounds and methods of making and using the same NZ623384A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ713357A NZ713357A (en) 2009-10-16 2010-10-15 Antimicrobial compounds and methods of making and using the same

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25247809P 2009-10-16 2009-10-16
US31428710P 2010-03-16 2010-03-16
US35820110P 2010-06-24 2010-06-24
NZ599290A NZ599290A (en) 2009-10-16 2010-10-15 Antimicrobial compounds and methods of making and using the same

Publications (1)

Publication Number Publication Date
NZ623384A true NZ623384A (en) 2016-06-24

Family

ID=43876906

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ713357A NZ713357A (en) 2009-10-16 2010-10-15 Antimicrobial compounds and methods of making and using the same
NZ623384A NZ623384A (en) 2009-10-16 2010-10-15 Antimicrobial compounds and methods of making and using the same

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NZ713357A NZ713357A (en) 2009-10-16 2010-10-15 Antimicrobial compounds and methods of making and using the same

Country Status (9)

Country Link
JP (6) JP2016121171A (en)
KR (3) KR20120101392A (en)
CN (5) CN107266470A (en)
AR (3) AR080559A1 (en)
EA (1) EA201500913A1 (en)
MY (2) MY165011A (en)
NZ (2) NZ713357A (en)
SG (3) SG10201406635QA (en)
TW (8) TW201825495A (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2777741A1 (en) 2009-10-16 2011-04-21 Rib-X Pharmaceuticals, Inc. Antimicrobial compounds and methods of making and using the same
AU2010306647B9 (en) 2009-10-16 2016-11-17 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
SG10201406635QA (en) * 2009-10-16 2014-11-27 Melinta Therapeutics Inc Antimicrobial compounds and methods of making and using the same
HUE036755T2 (en) * 2011-04-15 2018-07-30 Melinta Therapeutics Inc Antimicrobial compounds and methods of making and using the same
US9937183B2 (en) 2013-09-09 2018-04-10 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
WO2015035426A1 (en) 2013-09-09 2015-03-12 Melinta Therapeutics, Inc. Antimicrobial compunds and methods of making and using the same
US10947237B2 (en) 2015-03-11 2021-03-16 BioVersys AG Antimicrobial compounds and methods of making and using the same
CN110312722A (en) 2016-05-06 2019-10-08 生物验证系统股份公司 Antimicrobial and its preparation and application

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US3673184A (en) * 1970-09-02 1972-06-27 Dainippon Pharmaceutical Co Certain 2-substituted-5,8-dihydro-5-oxopyrido{8 2,3-d{9 pyrimidine-6-carboxylic acid derivatives
EP0067610A1 (en) * 1981-06-16 1982-12-22 Beecham Group Plc Penicillins, a process for their preparation and compositions containing them
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US6451968B1 (en) * 1991-05-24 2002-09-17 Isis Pharmaceuticals, Inc. Peptide nucleic acids
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US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
IT1263804B (en) * 1993-01-22 1996-09-03 Luso Farmaco Inst PYRIMIDINONIC DERIVATIVES MELT WITH NITROGEN HETEROCYCLES ACTIVATED IN II ANTAGONIST
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Also Published As

Publication number Publication date
JP2019038808A (en) 2019-03-14
JP2016153405A (en) 2016-08-25
AR080558A1 (en) 2012-04-18
JP2016172733A (en) 2016-09-29
TW201630914A (en) 2016-09-01
JP2018024653A (en) 2018-02-15
TWI621439B (en) 2018-04-21
TWI629277B (en) 2018-07-11
SG10201406634VA (en) 2014-11-27
TW201731849A (en) 2017-09-16
TW201124417A (en) 2011-07-16
CN104628729A (en) 2015-05-20
TW201125566A (en) 2011-08-01
NZ713357A (en) 2017-05-26
CN107266470A (en) 2017-10-20
CN108456211A (en) 2018-08-28
EA201500913A1 (en) 2015-12-30
KR101857694B1 (en) 2018-06-19
TW201726630A (en) 2017-08-01
AR080559A1 (en) 2012-04-18
TWI589294B (en) 2017-07-01
MY161870A (en) 2017-05-15
JP2018039784A (en) 2018-03-15
SG10201406631TA (en) 2014-11-27
SG10201406635QA (en) 2014-11-27
CN104628729B (en) 2018-11-06
KR20120101392A (en) 2012-09-13
TW201825495A (en) 2018-07-16
TW201622725A (en) 2016-07-01
JP2016121171A (en) 2016-07-07
AR080617A1 (en) 2012-04-25
KR20120099435A (en) 2012-09-10
KR20120099436A (en) 2012-09-10
TWI612048B (en) 2018-01-21
MY165011A (en) 2018-02-28
CN107445976A (en) 2017-12-08
TWI618707B (en) 2018-03-21
TW201125564A (en) 2011-08-01
CN105646370A (en) 2016-06-08

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