NZ595691A - Drug delivery composition - Google Patents
Drug delivery compositionInfo
- Publication number
- NZ595691A NZ595691A NZ595691A NZ59569110A NZ595691A NZ 595691 A NZ595691 A NZ 595691A NZ 595691 A NZ595691 A NZ 595691A NZ 59569110 A NZ59569110 A NZ 59569110A NZ 595691 A NZ595691 A NZ 595691A
- Authority
- NZ
- New Zealand
- Prior art keywords
- coating
- group
- medicament
- particles
- surface stabilizer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Disclosed is a composition comprising: a semipermeable coating; particles of a medicament having an effective average particle size of less than or about 2 um (micrometres) and a surface stabilizer adsorbed on the surface of the medicament particles; and a solubilizing agent. Semi-permeable coatings can be selected from the group consisting of a controlled-porosity microporous coating, a water swellable coating. Surface stabilizer is selected from the group consisting of hydroxypropyl methylcellulose (HPMC), dioctyl sodium sulfosuccinate (DOSS), sodium lauryl sulfate (SLS), hydroxypropyl cellulose, polyvinylpyrrolidone, sodium deoxycholate, block copolymers based on ethylene oxide and propylene oxide, copolymers of vinylpyrrolidone and vinyl acetate, lecithin, polyoxyethylene sorbitan fatty acid esters, albumin, lysozyme, gelatin, macrogol 15 hydroxystearate, tyloxapol, and polyethoxylated castor oil.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16804009P | 2009-04-09 | 2009-04-09 | |
PCT/US2010/030387 WO2010118228A1 (en) | 2009-04-09 | 2010-04-08 | Drug delivery composition |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ595691A true NZ595691A (en) | 2013-06-28 |
Family
ID=42934579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ595691A NZ595691A (en) | 2009-04-09 | 2010-04-08 | Drug delivery composition |
Country Status (15)
Country | Link |
---|---|
US (3) | US20100260858A1 (en) |
EP (2) | EP2416782A1 (en) |
JP (4) | JP2012523427A (en) |
KR (1) | KR20120022895A (en) |
CN (2) | CN102448447A (en) |
AU (2) | AU2010234339B2 (en) |
BR (2) | BRPI1010511A2 (en) |
CA (2) | CA2758258A1 (en) |
IL (1) | IL215608A0 (en) |
MX (2) | MX2011010621A (en) |
NZ (1) | NZ595691A (en) |
RU (3) | RU2589823C2 (en) |
SG (1) | SG175137A1 (en) |
TW (2) | TWI546088B (en) |
WO (2) | WO2010118228A1 (en) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100260858A1 (en) * | 2009-04-09 | 2010-10-14 | Elan Pharma International Limited | Drug delivery composition |
EP2424581B1 (en) | 2009-04-28 | 2017-03-01 | SurModics, Inc. | Devices and methods for delivery of bioactive agents |
CA2786819A1 (en) | 2010-01-13 | 2011-07-21 | Jazz Pharmaceuticals Plc | Method for titrating clozapine |
WO2011146583A2 (en) | 2010-05-19 | 2011-11-24 | Elan Pharma International Limited | Nanoparticulate cinacalcet formulations |
US10010514B2 (en) * | 2010-07-08 | 2018-07-03 | Wellesley Pharmaceuticals, Llc | Pharmaceutical formulation for reducing frequency of urination and method of use thereof |
US9861727B2 (en) | 2011-05-20 | 2018-01-09 | Surmodics, Inc. | Delivery of hydrophobic active agent particles |
US9757497B2 (en) * | 2011-05-20 | 2017-09-12 | Surmodics, Inc. | Delivery of coated hydrophobic active agent particles |
US10213529B2 (en) * | 2011-05-20 | 2019-02-26 | Surmodics, Inc. | Delivery of coated hydrophobic active agent particles |
CN104853749A (en) * | 2012-09-17 | 2015-08-19 | 塔瑞克斯制药有限公司 | Oral formulations of angiotensin |
JP6438406B2 (en) | 2012-11-05 | 2018-12-12 | サーモディクス,インコーポレイテッド | Compositions and methods for delivering hydrophobic bioactive agents |
US11246963B2 (en) | 2012-11-05 | 2022-02-15 | Surmodics, Inc. | Compositions and methods for delivery of hydrophobic active agents |
EP2968359B1 (en) * | 2013-03-12 | 2021-01-20 | Celltaxis, LLC | Methods of inhibiting leukotriene a4 hydrolase |
EP2968264A4 (en) | 2013-03-14 | 2016-11-02 | Celtaxsys Inc | Inhibitors of leukotriene a4 hydrolase |
TW201503912A (en) * | 2013-03-19 | 2015-02-01 | Novartis Ag | Pharmaceutical compositions comprising everolimus |
AU2014306759B2 (en) | 2013-08-12 | 2018-04-26 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
EP3169315B1 (en) | 2014-07-17 | 2020-06-24 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
US20160106737A1 (en) | 2014-10-20 | 2016-04-21 | Pharmaceutical Manufacturing Research Services, Inc. | Extended Release Abuse Deterrent Liquid Fill Dosage Form |
KR102274297B1 (en) * | 2014-11-06 | 2021-07-07 | 주식회사 엘지생활건강 | Cosmetic composition containing octylgallate |
WO2016185443A1 (en) | 2015-05-20 | 2016-11-24 | Novartis Ag | Pharmaceutical combination of everolimus with dactolisib |
KR101884230B1 (en) * | 2016-02-29 | 2018-08-01 | 주식회사 유영제약 | Formulation containing esomeprazole |
SG11201811351WA (en) * | 2016-07-05 | 2019-01-30 | Timilon Tech Acquisitions Llc | Compositions and methods for forming stable, liquid metal oxide/hydroxide formulations |
ES2960331T3 (en) * | 2016-09-17 | 2024-03-04 | Intas Pharmaceuticals Ltd | Clozapine Extended Release Pharmaceutical Composition |
US11534404B2 (en) * | 2016-10-06 | 2022-12-27 | Sucampo Ag | Multilayer beads for pharmaceutical use |
BR112019010470A2 (en) | 2016-11-23 | 2019-09-10 | Novartis Ag | immune response enhancement methods with everolimus, dactolisib or both |
US10898446B2 (en) | 2016-12-20 | 2021-01-26 | Surmodics, Inc. | Delivery of hydrophobic active agents from hydrophilic polyether block amide copolymer surfaces |
US11534397B2 (en) * | 2017-11-09 | 2022-12-27 | The Board Of Regents Of The University Of Oklahoma | Nanocrystal microparticles of poorly soluble drugs and methods of production and use thereof |
US10596165B2 (en) | 2018-02-12 | 2020-03-24 | resTORbio, Inc. | Combination therapies |
CN108371728B (en) * | 2018-03-09 | 2020-12-18 | 西南交通大学 | Preparation method of mussel-like contact antibacterial hydrogel for tissue repair |
CN108295264A (en) * | 2018-03-28 | 2018-07-20 | 五邑大学 | The application of polyvinylpyrrolidone k12 |
US11672781B2 (en) | 2018-05-07 | 2023-06-13 | Prana Biosciences Inc | Metaxalone formulations |
AU2019278935A1 (en) | 2018-05-31 | 2020-12-10 | Celltaxis, Llc | Method of reducing pulmonary exacerbations in respiratory disease patients |
CN109602952B (en) * | 2018-12-27 | 2021-05-18 | 上海北陆医药科技有限公司 | Long-acting slow-release cell scaffold and preparation method and application thereof |
US11918590B2 (en) * | 2021-12-15 | 2024-03-05 | Intas Pharmaceuticals Ltd. | Stable extended release pharmaceutical composition of clozapine |
Family Cites Families (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3173876A (en) * | 1960-05-27 | 1965-03-16 | John C Zobrist | Cleaning methods and compositions |
NL271831A (en) * | 1960-11-29 | |||
US3276586A (en) * | 1963-08-30 | 1966-10-04 | Rosaen Filter Co | Indicating means for fluid filters |
US3546142A (en) * | 1967-01-19 | 1970-12-08 | Amicon Corp | Polyelectrolyte structures |
DE1720701A1 (en) * | 1967-08-22 | 1971-07-15 | Bayer Ag | Crosslinkable lacquer resins |
FR2000803A1 (en) * | 1968-01-26 | 1969-09-12 | Kalle Ag | |
US3541006A (en) * | 1968-07-03 | 1970-11-17 | Amicon Corp | Ultrafiltration process |
US3615024A (en) * | 1968-08-26 | 1971-10-26 | Amicon Corp | High flow membrane |
BE758820A (en) * | 1969-11-13 | 1971-05-12 | Celanese Corp | PROCESS FOR THE PRODUCTION OF OPEN-CELL MICROPOROUS FILMS |
FR2105306A5 (en) * | 1970-08-07 | 1972-04-28 | Rhone Poulenc Sa | |
CA984567A (en) * | 1972-02-16 | 1976-03-02 | Albert E. Smith | Microporous polymer sheets |
US3852224A (en) * | 1972-09-14 | 1974-12-03 | Tee Pak Inc | Microporous films |
US4014334A (en) * | 1976-02-02 | 1977-03-29 | Alza Corporation | Laminated osmotic system for dispensing beneficial agent |
DE3000979A1 (en) * | 1980-01-12 | 1981-07-23 | Dr. Karl Thomae Gmbh, 7950 Biberach | NEW DIPYRIDAMOL RETARD FORMS AND METHOD FOR THEIR PRODUCTION |
US4576604A (en) * | 1983-03-04 | 1986-03-18 | Alza Corporation | Osmotic system with instant drug availability |
US4624847A (en) * | 1985-04-22 | 1986-11-25 | Alza Corporation | Drug delivery device for programmed delivery of beneficial drug |
US4971790A (en) * | 1986-02-07 | 1990-11-20 | Alza Corporation | Dosage form for lessening irritation of mocusa |
US4801461A (en) * | 1987-01-28 | 1989-01-31 | Alza Corporation | Pseudoephedrine dosage form |
GB8717168D0 (en) * | 1987-07-21 | 1987-08-26 | Roussel Lab Ltd | Controlled-release device |
US4946686A (en) * | 1987-09-24 | 1990-08-07 | Merck & Co., Inc. | Solubility modulated drug delivery system |
US5324280A (en) * | 1990-04-02 | 1994-06-28 | Alza Corporation | Osmotic dosage system for delivering a formulation comprising liquid carrier and drug |
US5145684A (en) * | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
US5260068A (en) * | 1992-05-04 | 1993-11-09 | Anda Sr Pharmaceuticals Inc. | Multiparticulate pulsatile drug delivery system |
DK0621032T3 (en) * | 1993-04-23 | 2000-10-23 | Novartis Ag | Medicinal product with controlled release |
US5558879A (en) * | 1995-04-28 | 1996-09-24 | Andrx Pharmaceuticals, Inc. | Controlled release formulation for water soluble drugs in which a passageway is formed in situ |
DE69709646T2 (en) * | 1996-03-12 | 2002-08-14 | Alza Corp | COMPOSITION AND DOSAGE WITH AN OPIOID ANTAGONIST |
DE19635676A1 (en) * | 1996-09-03 | 1998-03-05 | Basf Ag | Solid foamed active ingredient preparations |
US6110498A (en) * | 1996-10-25 | 2000-08-29 | Shire Laboratories, Inc. | Osmotic drug delivery system |
US5788987A (en) * | 1997-01-29 | 1998-08-04 | Poli Industria Chimica Spa | Methods for treating early morning pathologies |
US6045829A (en) * | 1997-02-13 | 2000-04-04 | Elan Pharma International Limited | Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers |
AU1534699A (en) * | 1997-12-05 | 1999-06-28 | Alza Corporation | Osmotic dosage form comprising first and second coats |
WO1999034751A1 (en) * | 1998-01-06 | 1999-07-15 | Sceusa Nicholas A | A drug dosage form based on the teorell-meyer gradient |
US6004584A (en) * | 1998-03-02 | 1999-12-21 | The Procter & Gamble Company | Highly absorbent body powders |
WO2000018374A1 (en) * | 1998-10-01 | 2000-04-06 | Elan Pharma International, Ltd. | Controlled release nanoparticulate compositions |
DK1126826T6 (en) * | 1998-11-02 | 2019-06-24 | Alkermes Pharma Ireland Ltd | Multiparticulate modified release of methylphenidate |
ATE260642T1 (en) * | 1998-12-17 | 2004-03-15 | Alza Corp | CONVERSION OF LIQUID-FILLED GELATIN CAPSULES INTO SYSTEMS WITH CONTROLLED ACTIVE RELEASE THROUGH MULTIPLE COATINGS |
US6267989B1 (en) * | 1999-03-08 | 2001-07-31 | Klan Pharma International Ltd. | Methods for preventing crystal growth and particle aggregation in nanoparticulate compositions |
JP2003513033A (en) * | 1999-10-29 | 2003-04-08 | メルク エンド カムパニー インコーポレーテッド | Osmotic controlled release drug delivery device |
US20030180352A1 (en) * | 1999-11-23 | 2003-09-25 | Patel Mahesh V. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
EP1269994A3 (en) * | 2001-06-22 | 2003-02-12 | Pfizer Products Inc. | Pharmaceutical compositions comprising drug and concentration-enhancing polymers |
US20030068356A1 (en) * | 2001-07-10 | 2003-04-10 | Pather S. Indiran | Sequential drug delivery systems |
US8329217B2 (en) * | 2001-11-06 | 2012-12-11 | Osmotica Kereskedelmi Es Szolgaltato Kft | Dual controlled release dosage form |
TW200302748A (en) * | 2002-02-01 | 2003-08-16 | Pfizer Prod Inc | Osmotic delivery system |
AU2003234452A1 (en) * | 2002-05-06 | 2003-11-11 | Elan Pharma International Ltd. | Nanoparticulate nystatin formulations |
US20080220074A1 (en) * | 2002-10-04 | 2008-09-11 | Elan Corporation Plc | Gamma radiation sterilized nanoparticulate docetaxel compositions and methods of making same |
US7611728B2 (en) * | 2003-09-05 | 2009-11-03 | Supernus Pharmaceuticals, Inc. | Osmotic delivery of therapeutic compounds by solubility enhancement |
WO2005063206A1 (en) * | 2003-12-23 | 2005-07-14 | Alza Corporation | Methods and dosage forms for increasing solubility of drug compositions for controlled delivery |
US20050196446A1 (en) * | 2004-03-05 | 2005-09-08 | Huang Hai Y. | Polymeric compositions and dosage forms comprising the same |
US7728015B2 (en) * | 2004-04-22 | 2010-06-01 | Mor Research Applications Ltd. | Compositions for weight management |
JP2008524239A (en) * | 2004-12-15 | 2008-07-10 | エラン ファーマ インターナショナル リミティド | Nanoparticulate tacrolimus formulation |
CN101132768A (en) * | 2004-12-15 | 2008-02-27 | 伊兰制药国际有限公司 | Nanoparticulate tacrolimus formulations |
US20080254114A1 (en) * | 2005-03-03 | 2008-10-16 | Elan Corporation Plc | Controlled Release Compositions Comprising Heterocyclic Amide Derivative Nanoparticles |
WO2007022501A2 (en) * | 2005-08-18 | 2007-02-22 | Microbia, Inc. | Useful indole compounds |
EA017290B1 (en) * | 2005-11-28 | 2012-11-30 | Домейн Раша Инвестментс Лимитед | Ganaxolone-based formulations |
EP1976492B8 (en) * | 2006-01-27 | 2018-07-04 | Adare Pharmaceuticals, Inc. | Drug delivery systems comprising weakly basic drugs and organic acids |
ES2531215T3 (en) * | 2006-01-27 | 2015-03-11 | Aptalis Pharmatech Inc | Drug delivery systems comprising a weakly basic serotonin 5-HT3 selective blocking agent and organic acids |
CA2661683C (en) * | 2006-08-31 | 2015-11-24 | Eurand, Inc | Drug delivery systems comprising solid solutions of weakly basic drugs |
US20090004281A1 (en) * | 2007-06-26 | 2009-01-01 | Biovail Laboratories International S.R.L. | Multiparticulate osmotic delivery system |
US8133506B2 (en) * | 2008-03-12 | 2012-03-13 | Aptalis Pharmatech, Inc. | Drug delivery systems comprising weakly basic drugs and organic acids |
TWI519322B (en) * | 2008-04-15 | 2016-02-01 | 愛戴爾製藥股份有限公司 | Compositions comprising weakly basic drugs and controlled-release dosage forms |
RU2403041C2 (en) * | 2008-12-18 | 2010-11-10 | Автономная некоммерческая организация "Институт молекулярной диагностики" (АНО "ИнМоДи") | D-cycloserin-based medication of plolonged action with dosed release in target organs for treatment of resistant forms of tuberculosis |
US20100260858A1 (en) * | 2009-04-09 | 2010-10-14 | Elan Pharma International Limited | Drug delivery composition |
-
2010
- 2010-04-08 US US12/757,005 patent/US20100260858A1/en not_active Abandoned
- 2010-04-08 EP EP10762437A patent/EP2416782A1/en not_active Withdrawn
- 2010-04-08 KR KR1020117026643A patent/KR20120022895A/en not_active Application Discontinuation
- 2010-04-08 CN CN201080023470XA patent/CN102448447A/en active Pending
- 2010-04-08 US US12/757,024 patent/US20100260859A1/en not_active Abandoned
- 2010-04-08 AU AU2010234339A patent/AU2010234339B2/en not_active Ceased
- 2010-04-08 CA CA2758258A patent/CA2758258A1/en not_active Abandoned
- 2010-04-08 WO PCT/US2010/030387 patent/WO2010118228A1/en active Application Filing
- 2010-04-08 JP JP2012504860A patent/JP2012523427A/en active Pending
- 2010-04-08 RU RU2011145279/15A patent/RU2589823C2/en not_active IP Right Cessation
- 2010-04-08 BR BRPI1010511-5A patent/BRPI1010511A2/en not_active IP Right Cessation
- 2010-04-08 CA CA2757979A patent/CA2757979A1/en not_active Abandoned
- 2010-04-08 WO PCT/US2010/030393 patent/WO2010118232A1/en active Application Filing
- 2010-04-08 SG SG2011073517A patent/SG175137A1/en unknown
- 2010-04-08 MX MX2011010621A patent/MX2011010621A/en not_active Application Discontinuation
- 2010-04-08 BR BRPI1010301A patent/BRPI1010301A2/en not_active IP Right Cessation
- 2010-04-08 EP EP10762434.8A patent/EP2416764A4/en not_active Withdrawn
- 2010-04-08 CN CN201610091458.1A patent/CN105581984A/en active Pending
- 2010-04-08 NZ NZ595691A patent/NZ595691A/en not_active IP Right Cessation
- 2010-04-08 RU RU2011145278/15A patent/RU2011145278A/en not_active Application Discontinuation
- 2010-04-08 MX MX2011010620A patent/MX2011010620A/en unknown
- 2010-04-08 AU AU2010234343A patent/AU2010234343A1/en not_active Abandoned
- 2010-04-08 JP JP2012504864A patent/JP2012523428A/en not_active Withdrawn
- 2010-04-08 RU RU2016120727A patent/RU2016120727A/en not_active Application Discontinuation
- 2010-04-09 TW TW099111212A patent/TWI546088B/en not_active IP Right Cessation
- 2010-04-09 TW TW099111214A patent/TW201039867A/en unknown
-
2011
- 2011-10-06 IL IL215608A patent/IL215608A0/en unknown
-
2014
- 2014-09-08 JP JP2014182031A patent/JP5934312B2/en not_active Expired - Fee Related
-
2015
- 2015-06-22 US US14/746,035 patent/US20150283092A1/en not_active Abandoned
-
2016
- 2016-05-06 JP JP2016092931A patent/JP2016138136A/en not_active Withdrawn
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NZ595691A (en) | Drug delivery composition | |
ES2189232T5 (en) | Gastrically protected omeprazole microgranules, procedure for obtaining and pharmaceutical preparations | |
EA033370B1 (en) | Formulations of rifaximin and uses thereof | |
HRP20151357T1 (en) | The use of solid carrier particles to improve the processability of a pharmaceutical agent | |
KR20100014629A (en) | Modified dosage forms of tacrolimus | |
UA102885C2 (en) | Pharmaceutical composition for oral administration | |
JP5524624B2 (en) | Aqueous film coating solution, film coated granule, and tablet using the same | |
JP2014208655A5 (en) | ||
WO2012075015A2 (en) | Oral metronidazole pharmaceutical compositions | |
IL260229B2 (en) | St-246 (tecovirimat monohydrate) suspension formulations | |
MX2013000284A (en) | Orally disintegrating tablet. | |
US20080069870A1 (en) | Controlled Release Compositions Comprising a Cephalosporin for the Treatment of a Bacterial Infection | |
WO2012020301A3 (en) | Oral controlled release pharmaceutical compositions of blonanserin | |
WO2011045774A2 (en) | Extended release pharmaceutical compositions of paliperidone and processes of preparation thereof | |
WO2018229784A1 (en) | Pharmaceutical compositions of dabigatran | |
US20100209500A1 (en) | Controlled release budesonide minitablets | |
JP4771956B2 (en) | Composition of a quaternary ammonium compound containing a bioavailability enhancer | |
TW201332591A (en) | Pharmaceutical composition for the prolonged release of trimetazidine | |
US8945616B2 (en) | Controlled release budesonide minitablets | |
AU2006209212B2 (en) | Controlled release compositions comprising an antipsychotic agent | |
PH12014502609B1 (en) | Multilayer coating form of orally administered pharmaceutical composition containing omega-3 fatty acid or alkyl ester thereof and statin based drug | |
WO2011080570A8 (en) | Extended release pharmaceutical composition comprising linezolid and process for preparing the same | |
JP2016504390A5 (en) | ||
CA2433915A1 (en) | Improved controlled release oral dosage form | |
EP3848037A1 (en) | Solid pharmaceutical composition containing 1,3,5-triazine derivative or salt thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PSEA | Patent sealed | ||
RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 08 APR 2017 BY COMPUTER PACKAGES INC Effective date: 20140429 |
|
LAPS | Patent lapsed |