NZ579478A - Epha3 antibodies for the treatment of solid tumors - Google Patents
Epha3 antibodies for the treatment of solid tumorsInfo
- Publication number
- NZ579478A NZ579478A NZ579478A NZ57947808A NZ579478A NZ 579478 A NZ579478 A NZ 579478A NZ 579478 A NZ579478 A NZ 579478A NZ 57947808 A NZ57947808 A NZ 57947808A NZ 579478 A NZ579478 A NZ 579478A
- Authority
- NZ
- New Zealand
- Prior art keywords
- treatment
- solid tumors
- epha3 antibodies
- epha3
- antibodies
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 101150016325 EPHA3 gene Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
- A61K51/1033—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants against receptors for cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Optics & Photonics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89384807P | 2007-03-08 | 2007-03-08 | |
| PCT/US2008/003149 WO2008112192A2 (en) | 2007-03-08 | 2008-03-10 | Epha3 antibodies for the treatment of solid tumors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ579478A true NZ579478A (en) | 2012-08-31 |
Family
ID=39689392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ579478A NZ579478A (en) | 2007-03-08 | 2008-03-10 | Epha3 antibodies for the treatment of solid tumors |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8637016B2 (Direct) |
| EP (2) | EP2136838B1 (Direct) |
| JP (1) | JP5311060B2 (Direct) |
| CN (1) | CN101641115B (Direct) |
| AU (1) | AU2008226905C1 (Direct) |
| CA (1) | CA2679986C (Direct) |
| DK (1) | DK3199180T3 (Direct) |
| ES (1) | ES2910298T3 (Direct) |
| IL (1) | IL200764A (Direct) |
| NZ (1) | NZ579478A (Direct) |
| PL (1) | PL3199180T3 (Direct) |
| PT (1) | PT3199180T (Direct) |
| WO (1) | WO2008112192A2 (Direct) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8680019B2 (en) | 2007-08-10 | 2014-03-25 | Protelica, Inc. | Universal fibronectin Type III binding-domain libraries |
| US8470966B2 (en) | 2007-08-10 | 2013-06-25 | Protelica, Inc. | Universal fibronectin type III binding-domain libraries |
| AU2008287426B2 (en) | 2007-08-10 | 2014-06-26 | Protelica, Inc. | Universal fibronectin type III binding-domain libraries |
| US8834870B2 (en) * | 2009-03-06 | 2014-09-16 | Kalobios Pharmaceuticals, Inc. | Treatment of leukemias and chronic myeloproliferative diseases with antibodies to EphA3 |
| WO2011053465A1 (en) * | 2009-10-14 | 2011-05-05 | Kalobios Pharmaceuticals, Inc. | Antibodies to epha3 |
| WO2011123819A2 (en) * | 2010-04-01 | 2011-10-06 | Kalobios Pharmaceuticals, Inc. | Epha3 antibodies for the treatment of multiple myeloma |
| WO2011160132A2 (en) * | 2010-06-18 | 2011-12-22 | Kalobios Pharmaceuticals, Inc. | Detection of epha3 as a marker of the presence of a solid tumor |
| RU2592672C9 (ru) * | 2010-12-08 | 2016-11-27 | СтемСентРкс, Инк. | Новые модуляторы и способы их применения |
| JP6400470B2 (ja) | 2011-05-16 | 2018-10-03 | ジェネロン（シャンハイ）コーポレイション リミテッド | 多重特異性Ｆａｂ融合タンパク質および使用法 |
| JP2014527054A (ja) * | 2011-08-12 | 2014-10-09 | カロバイオス ファーマシューティカルズ インコーポレイティッド | 骨髄内の異常血管系上に発現したＥｐｈＡ３を標的とすることによる、血液増殖性疾患を処置する方法 |
| CA2930243A1 (en) | 2013-11-11 | 2015-05-14 | Wake Forest University Health Sciences | Epha3 and multi-valent targeting of tumors |
| US10870701B2 (en) | 2016-03-15 | 2020-12-22 | Generon (Shanghai) Corporation Ltd. | Multispecific fab fusion proteins and use thereof |
| EP3847196A4 (en) | 2018-09-07 | 2023-01-04 | ITabMed (HK) Limited | BISPECIFIC ANTIGEN BINDING PROTEINS AND USES THEREOF |
| IL291937A (en) * | 2019-10-09 | 2022-06-01 | Council Queensland Inst Medical Res | Targeting epha3 and uses thereof |
Family Cites Families (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4997913A (en) * | 1986-06-30 | 1991-03-05 | Oncogen | pH-sensitive immunoconjugates and methods for their use in tumor therapy |
| DE3883899T3 (de) | 1987-03-18 | 1999-04-22 | Sb2, Inc., Danville, Calif. | Geänderte antikörper. |
| US5677425A (en) | 1987-09-04 | 1997-10-14 | Celltech Therapeutics Limited | Recombinant antibody |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| DE69133476T2 (de) | 1990-08-29 | 2006-01-05 | GenPharm International, Inc., Palo Alto | Transgene Mäuse fähig zur Produktion heterologer Antikörper |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| JP3955316B2 (ja) | 1991-06-21 | 2007-08-08 | ザ・ワルター・アンド・エリザ・ホール・インスティテュート・オヴ・メディカル・リサーチ | 新規レセプター型チロシンキナーゼ及びその用途 |
| US5714350A (en) | 1992-03-09 | 1998-02-03 | Protein Design Labs, Inc. | Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region |
| EP0640094A1 (en) | 1992-04-24 | 1995-03-01 | The Board Of Regents, The University Of Texas System | Recombinant production of immunoglobulin-like domains in prokaryotic cells |
| NO175798C (no) | 1992-07-22 | 1994-12-07 | Sinvent As | Fremgangsmåte og anordning til aktiv stöydemping i et lokalt område |
| US5885573A (en) | 1993-06-01 | 1999-03-23 | Arch Development Corporation | Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies |
| US6121022A (en) | 1995-04-14 | 2000-09-19 | Genentech, Inc. | Altered polypeptides with increased half-life |
| US5869046A (en) | 1995-04-14 | 1999-02-09 | Genentech, Inc. | Altered polypeptides with increased half-life |
| US5811097A (en) * | 1995-07-25 | 1998-09-22 | The Regents Of The University Of California | Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling |
| US5770380A (en) | 1996-09-13 | 1998-06-23 | University Of Pittsburgh | Synthetic antibody mimics--multiple peptide loops attached to a molecular scaffold |
| US6277375B1 (en) | 1997-03-03 | 2001-08-21 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
| US6342220B1 (en) * | 1997-08-25 | 2002-01-29 | Genentech, Inc. | Agonist antibodies |
| US6194551B1 (en) | 1998-04-02 | 2001-02-27 | Genentech, Inc. | Polypeptide variants |
| US6864227B1 (en) | 1998-04-13 | 2005-03-08 | California Institute Of Technology | Artery-and vein-specific proteins and uses therefor |
| DK1071700T3 (da) | 1998-04-20 | 2010-06-07 | Glycart Biotechnology Ag | Glykosylerings-modifikation af antistoffer til forbedring af antistofafhængig cellulær cytotoksicitet |
| GB9809951D0 (en) | 1998-05-08 | 1998-07-08 | Univ Cambridge Tech | Binding molecules |
| SI1135153T1 (Direct) | 1998-11-20 | 2005-08-31 | Genentech Inc | |
| EP1051432B1 (en) | 1998-12-08 | 2007-01-24 | Biovation Limited | Method for reducing immunogenicity of proteins |
| US7115396B2 (en) | 1998-12-10 | 2006-10-03 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| US6818418B1 (en) | 1998-12-10 | 2004-11-16 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
| EP2364997A3 (en) | 1999-01-15 | 2012-07-04 | Genentech, Inc. | Polypeptide variants with altered effector function |
| EP1163339A1 (en) | 1999-04-01 | 2001-12-19 | Innogenetics N.V. | A polypeptide structure for use as a scaffold |
| ES2420835T3 (es) | 1999-04-09 | 2013-08-27 | Kyowa Hakko Kirin Co., Ltd. | Procedimiento para controlar la actividad de las moléculas inmunofuncionales |
| US20040018199A1 (en) | 1999-10-15 | 2004-01-29 | Raj Bandaru | Compositions and methods of use for an ephrin receptor |
| EP1094110A1 (en) | 1999-10-21 | 2001-04-25 | Leadd B.V. | Apoptosis inducing proteinaceous substance |
| MXPA03000105A (es) | 2000-06-28 | 2004-09-13 | Glycofi Inc | Metodo para producir glicoproteinas modificadas. |
| US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
| EP3263702A1 (en) | 2000-10-06 | 2018-01-03 | Kyowa Hakko Kirin Co., Ltd. | Cells producing antibody compositions |
| AU2001294175A1 (en) | 2000-10-06 | 2002-04-22 | Kyowa Hakko Kogyo Co. Ltd. | Method of purifying antibody |
| AU2002248184C1 (en) | 2000-12-12 | 2018-01-04 | Board Of Regents, The University Of Texas System | Molecules with extended half-lives, compositions and uses thereof |
| US7041302B2 (en) * | 2001-01-09 | 2006-05-09 | Biother Corporation | Therapeutic modulation of the tumor inflammatory response |
| US6652853B2 (en) * | 2001-03-08 | 2003-11-25 | Ludwig Institute For Cancer Research | Method for treating cancer using A33 specific antibodies and chemotherapeutic agents |
| WO2002076499A2 (en) * | 2001-03-23 | 2002-10-03 | Aphton Corporation | Combination treatment of pancreatic cancer |
| US20050049194A1 (en) | 2001-11-09 | 2005-03-03 | Jonas Frisen | Use of ephrins and related molecules to regulate cellular proliferation |
| US7317091B2 (en) | 2002-03-01 | 2008-01-08 | Xencor, Inc. | Optimized Fc variants |
| KR101060361B1 (ko) | 2002-03-19 | 2011-08-29 | 스티칭 디엔스트 랜드보위쿤디그 온데조에크 | 식물에서 글리칸 프로세싱의 최적화 |
| CA2499580A1 (en) | 2002-09-24 | 2004-04-08 | The Burnham Institute | Novel agents that modulate eph receptor activity |
| DK2364996T3 (en) | 2002-09-27 | 2017-02-06 | Xencor Inc | Optimized Fc variants and methods for their formation |
| AU2003900541A0 (en) | 2003-02-07 | 2003-02-20 | Ludwig Institute For Cancer Research | Modulation of cell adhesion and tumour cell metastasis |
| WO2005021710A2 (en) | 2003-06-02 | 2005-03-10 | University Of Miami | Chimeric molecules and methods of use |
| JP4782700B2 (ja) | 2004-01-20 | 2011-09-28 | カロバイオス ファーマシューティカルズ インコーポレイティッド | 最低限必須な結合決定基を用いた抗体特異性の移入 |
| CA2577329A1 (en) | 2004-08-16 | 2006-03-02 | Medimmune, Inc. | Eph receptor fc variants with enhanced antibody dependent cell-mediated cytotoxicity activity |
| WO2006052409A2 (en) | 2004-10-23 | 2006-05-18 | Case Western Reserve University | Peptide and small molecule agonists of epha and their uses |
| EP1809326A4 (en) * | 2004-10-27 | 2009-11-04 | Medimmune Inc | MODULATION OF ANTIBODY SPECIFICITY BY MEASURING ADAPTATION OF ITS AFFINITY TO AN APPARENT ANTIGEN |
| US20060134098A1 (en) | 2004-11-16 | 2006-06-22 | Kalobios, Inc. | Immunoglobulin variable region cassette exchange |
| NZ598048A (en) | 2006-01-17 | 2013-05-31 | Synthon Biopharmaceuticals Bv | Compositions and methods for humanization and optimization of n-glycans in plants |
| US7846724B2 (en) | 2006-04-11 | 2010-12-07 | Hoffmann-La Roche Inc. | Method for selecting CHO cell for production of glycosylated antibodies |
-
2008
- 2008-03-10 DK DK17159714.9T patent/DK3199180T3/da active
- 2008-03-10 JP JP2009552761A patent/JP5311060B2/ja active Active
- 2008-03-10 WO PCT/US2008/003149 patent/WO2008112192A2/en not_active Ceased
- 2008-03-10 AU AU2008226905A patent/AU2008226905C1/en active Active
- 2008-03-10 ES ES17159714T patent/ES2910298T3/es active Active
- 2008-03-10 US US12/045,589 patent/US8637016B2/en active Active
- 2008-03-10 PT PT171597149T patent/PT3199180T/pt unknown
- 2008-03-10 CN CN2008800076268A patent/CN101641115B/zh active Active
- 2008-03-10 EP EP08726647.4A patent/EP2136838B1/en active Active
- 2008-03-10 PL PL17159714.9T patent/PL3199180T3/pl unknown
- 2008-03-10 EP EP17159714.9A patent/EP3199180B1/en active Active
- 2008-03-10 NZ NZ579478A patent/NZ579478A/xx not_active IP Right Cessation
- 2008-03-10 CA CA2679986A patent/CA2679986C/en active Active
-
2009
- 2009-09-06 IL IL200764A patent/IL200764A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008226905A1 (en) | 2008-09-18 |
| PL3199180T3 (pl) | 2022-08-08 |
| EP3199180B1 (en) | 2022-01-05 |
| AU2008226905C1 (en) | 2014-11-06 |
| IL200764A (en) | 2017-01-31 |
| EP2136838A2 (en) | 2009-12-30 |
| CN101641115A (zh) | 2010-02-03 |
| US8637016B2 (en) | 2014-01-28 |
| ES2910298T3 (es) | 2022-05-12 |
| WO2008112192A2 (en) | 2008-09-18 |
| AU2008226905B2 (en) | 2014-05-01 |
| EP2136838B1 (en) | 2017-03-08 |
| JP2010520290A (ja) | 2010-06-10 |
| WO2008112192A3 (en) | 2008-11-13 |
| IL200764A0 (en) | 2010-05-17 |
| PT3199180T (pt) | 2022-04-01 |
| JP5311060B2 (ja) | 2013-10-09 |
| CN101641115B (zh) | 2013-04-24 |
| CA2679986A1 (en) | 2008-09-18 |
| EP3199180A1 (en) | 2017-08-02 |
| DK3199180T3 (da) | 2022-03-21 |
| CA2679986C (en) | 2018-03-06 |
| US20080286272A1 (en) | 2008-11-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ579478A (en) | Epha3 antibodies for the treatment of solid tumors | |
| HUS2100051I1 (hu) | Kompozíciók és eljárások sejtproliferációs rendellenességek kezelésére | |
| WO2008124660A3 (en) | Methods and compositions for the treatment of cancer | |
| MX2009008430A (es) | Anticuerpos anti-robo4 y sus usos. | |
| AU2016204376A1 (en) | MicroRNA-based methods and compositions for the diagnosis and treatment of ovarian cancer | |
| MX345909B (es) | Anticuerpos anti-fgfr3 y métodos que los utilizan. | |
| TW200732349A (en) | Anti-OX40L antibodies and methods using same | |
| MY148635A (en) | Anti-tat226 antibodies and immunoconjugates | |
| MX2010006576A (es) | Composiciones y metodos para producir isopreno. | |
| EP1893196A4 (en) | DIARYLHYDANTOIN CONNECTIONS | |
| MX2009003938A (es) | Anticuerpos e inmunoconjugados y sus usos. | |
| IL244803A0 (en) | Human anti-beta7 antibodies and their use | |
| MX2009008347A (es) | Oxabicicloheptanos y oxabicicloheptenos, su preparacion y uso. | |
| PH12013502230A1 (en) | Multispecific antibodies | |
| PH12015500550A1 (en) | Anti-notch1 nrr antibodies and methods using same | |
| MX2020005214A (es) | Formulaciones de anticuerpos. | |
| PL1765391T3 (pl) | Kompozycje bakteryjne do leczenia nowotworów | |
| MX2012012966A (es) | Indoles. | |
| WO2007053573A3 (en) | Treatment of cancer with sorafenib | |
| WO2008027600A3 (en) | Imatinib compositions | |
| MX2009013170A (es) | Particulas de silice y metodos para prepararlas y utilizarlas. | |
| TW200738751A (en) | Anti-EphrinB2 antibodies and methods using same | |
| PH12013502194A1 (en) | Antibodies to egfl7 and methods for their use | |
| WO2007081751A9 (en) | Compositions and methods for the treatment of cancer | |
| MY150643A (en) | Methods and compositions for targeting hepsin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ASS | Change of ownership |
Owner name: LUDWIG INSTITUTE FOR CANCER RESEARCH, US Free format text: OLD OWNER(S): KALOBIOS PHARMACEUTICALS, INC.; MONASH UNIVERSITY; LUDWIG INSTITUTE FOR CANCER RESEARCH LIMITED; MARTIN LACKMANN; ANDREW MARK SCOTT; CARMELINA MURONE; CATHERINE TO; MONASH UNIVERSITY; LUDWIG INSTITUTE FOR CANCER RESEARCH; KALOBIOS PHARMACEUTICALS, INC. Owner name: MONASH UNIVERSITY, AU Free format text: OLD OWNER(S): KALOBIOS PHARMACEUTICALS, INC.; MONASH UNIVERSITY; LUDWIG INSTITUTE FOR CANCER RESEARCH LIMITED; MARTIN LACKMANN; ANDREW MARK SCOTT; CARMELINA MURONE; CATHERINE TO; MONASH UNIVERSITY; LUDWIG INSTITUTE FOR CANCER RESEARCH; KALOBIOS PHARMACEUTICALS, INC. Owner name: KALOBIOS PHARMACEUTICALS, INC., US Free format text: OLD OWNER(S): KALOBIOS PHARMACEUTICALS, INC.; MONASH UNIVERSITY; LUDWIG INSTITUTE FOR CANCER RESEARCH LIMITED; MARTIN LACKMANN; ANDREW MARK SCOTT; CARMELINA MURONE; CATHERINE TO; MONASH UNIVERSITY; LUDWIG INSTITUTE FOR CANCER RESEARCH; KALOBIOS PHARMACEUTICALS, INC. |
|
| S883 | Correction of error according to section 88(3) (mistake in register caused on part of patentee or applicant) |
Free format text: CORRECTION TO APPLICANT CHAIN OF TITLE (71) |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 10 MAR 2016 BY CPA GLOBAL Effective date: 20150205 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 10 MAR 2017 BY CPA GLOBAL Effective date: 20160304 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 10 MAR 2018 BY AJ PARK Effective date: 20170303 |
|
| LAPS | Patent lapsed |