NZ572012A - Anticancer treatment with a combination of taxanes and 13-deoxyanthracyclines - Google Patents
Anticancer treatment with a combination of taxanes and 13-deoxyanthracyclinesInfo
- Publication number
- NZ572012A NZ572012A NZ572012A NZ57201207A NZ572012A NZ 572012 A NZ572012 A NZ 572012A NZ 572012 A NZ572012 A NZ 572012A NZ 57201207 A NZ57201207 A NZ 57201207A NZ 572012 A NZ572012 A NZ 572012A
- Authority
- NZ
- New Zealand
- Prior art keywords
- composition
- taxane
- iponz
- alkyl
- received
- Prior art date
Links
- 229940123237 Taxane Drugs 0.000 title claims abstract 8
- 238000011394 anticancer treatment Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 claims abstract 8
- 229940045799 anthracyclines and related substance Drugs 0.000 claims abstract 7
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 claims abstract 6
- 230000001093 anti-cancer Effects 0.000 claims abstract 4
- RGVRUQHYQSORBY-JIGXQNLBSA-N (7s,9r)-7-[(2r,4s,5s,6s)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyethyl)-4-methoxy-8,10-dihydro-7h-tetracene-5,12-dione Chemical compound O([C@H]1C[C@](O)(CCO)CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 RGVRUQHYQSORBY-JIGXQNLBSA-N 0.000 claims abstract 3
- UHYFCDBUKBJSFA-JYFLSIMMSA-N 13-deoxycarminomycin Chemical compound O([C@H]1C[C@](CC2=C(O)C=3C(=O)C4=CC=CC(O)=C4C(=O)C=3C(O)=C21)(O)CC)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 UHYFCDBUKBJSFA-JYFLSIMMSA-N 0.000 claims abstract 3
- XAMIMZAWZUSOPA-JIGXQNLBSA-N 13-deoxydaunorubicin Chemical compound O([C@H]1C[C@](CC2=C(O)C=3C(=O)C4=CC=CC(OC)=C4C(=O)C=3C(O)=C21)(O)CC)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 XAMIMZAWZUSOPA-JIGXQNLBSA-N 0.000 claims abstract 3
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 claims abstract 3
- 229930012538 Paclitaxel Natural products 0.000 claims abstract 3
- 125000000217 alkyl group Chemical group 0.000 claims abstract 3
- 150000001875 compounds Chemical class 0.000 claims abstract 3
- 229960003668 docetaxel Drugs 0.000 claims abstract 3
- 229960001592 paclitaxel Drugs 0.000 claims abstract 3
- 150000003839 salts Chemical class 0.000 claims abstract 3
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims abstract 3
- 206010028980 Neoplasm Diseases 0.000 claims abstract 2
- 201000011510 cancer Diseases 0.000 claims abstract 2
- 241000220221 Rosales Species 0.000 claims 2
- WPJRFCZKZXBUNI-HCWXCVPCSA-N daunosamine Chemical group C[C@H](O)[C@@H](O)[C@@H](N)CC=O WPJRFCZKZXBUNI-HCWXCVPCSA-N 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 1
- 244000007835 Cyamopsis tetragonoloba Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/408,000 US7776832B2 (en) | 2006-04-21 | 2006-04-21 | Anticancer treatment with a combination of taxanes and 13-deoxyanthracyclines |
| PCT/US2007/067225 WO2007124489A2 (en) | 2006-04-21 | 2007-04-23 | Anticancer treatment with a combination of taxanes and 13-deoxyanthracyclines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ572012A true NZ572012A (en) | 2011-09-30 |
Family
ID=38620193
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ572012A NZ572012A (en) | 2006-04-21 | 2007-04-23 | Anticancer treatment with a combination of taxanes and 13-deoxyanthracyclines |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7776832B2 (pl) |
| EP (1) | EP2010191B1 (pl) |
| JP (1) | JP5011377B2 (pl) |
| KR (1) | KR101514336B1 (pl) |
| CN (1) | CN101426509A (pl) |
| AU (1) | AU2007240264B2 (pl) |
| CA (1) | CA2649753C (pl) |
| CO (1) | CO6190526A2 (pl) |
| DK (1) | DK2010191T3 (pl) |
| ES (1) | ES2840977T3 (pl) |
| IL (1) | IL194707A (pl) |
| MX (1) | MX2008013546A (pl) |
| MY (1) | MY148571A (pl) |
| NZ (1) | NZ572012A (pl) |
| PL (1) | PL2010191T3 (pl) |
| PT (1) | PT2010191T (pl) |
| RU (1) | RU2421224C2 (pl) |
| UA (1) | UA90597C2 (pl) |
| WO (1) | WO2007124489A2 (pl) |
| ZA (1) | ZA200808892B (pl) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20110111321A (ko) * | 2009-01-30 | 2011-10-10 | 이난타 파마슈티칼스, 인코포레이티드 | Ｃ형 간염을 예방하거나 치료하기 위한 사이클로스포린 유사체 |
| US8481483B2 (en) * | 2009-02-19 | 2013-07-09 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
| US8367053B2 (en) * | 2009-07-09 | 2013-02-05 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
| US8349312B2 (en) * | 2009-07-09 | 2013-01-08 | Enanta Pharmaceuticals, Inc. | Proline substituted cyclosporin analogues |
| US8685917B2 (en) * | 2009-07-09 | 2014-04-01 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
| US8623814B2 (en) * | 2010-02-23 | 2014-01-07 | Enanta Pharmaceuticals, Inc. | Antiviral agents |
| HRP20200793T1 (hr) | 2011-05-09 | 2020-10-16 | Mayo Foundation For Medical Education And Research | Liječenje raka |
| WO2014055415A1 (en) | 2012-10-01 | 2014-04-10 | Mayo Foundation For Medical Education And Research | Cancer treatments |
| EP3154586B1 (en) | 2014-06-13 | 2020-05-27 | Mayo Foundation for Medical Education and Research | Treating lymphomas |
| MX2016016617A (es) | 2014-06-16 | 2017-03-23 | Mayo Foundation | Tratamiento de mielomas. |
| US9446148B2 (en) | 2014-10-06 | 2016-09-20 | Mayo Foundation For Medical Education And Research | Carrier-antibody compositions and methods of making and using the same |
| EP3265059A4 (en) * | 2015-03-03 | 2018-08-29 | Cureport Inc. | Combination liposomal pharmaceutical formulations |
| TW201707725A (zh) | 2015-08-18 | 2017-03-01 | 美國馬友醫藥教育研究基金會 | 載體－抗體組合物及其製造及使用方法 |
| TW201713360A (en) | 2015-10-06 | 2017-04-16 | Mayo Foundation | Methods of treating cancer using compositions of antibodies and carrier proteins |
| EP3399861A4 (en) | 2016-01-07 | 2019-08-07 | Mayo Foundation for Medical Education and Research | METHOD FOR THE TREATMENT OF CANCER WITH INTERFERON |
| US11351254B2 (en) | 2016-02-12 | 2022-06-07 | Mayo Foundation For Medical Education And Research | Hematologic cancer treatments |
| CA3018341A1 (en) | 2016-03-21 | 2017-09-28 | Mayo Foundation For Medical Education And Research | Methods for reducing toxicity of a chemotherapeutic drug |
| CA3018340A1 (en) * | 2016-03-21 | 2017-09-28 | Mayo Foundation For Medical Education And Research | Methods for improving the therapeutic index for a chemotherapeutic drug |
| US10618969B2 (en) | 2016-04-06 | 2020-04-14 | Mayo Foundation For Medical Education And Research | Carrier-binding agent compositions and methods of making and using the same |
| KR20220151022A (ko) | 2016-09-01 | 2022-11-11 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 암 치료용 담체－ｐｄ－ｌ１ 결합제 조성물 |
| MX2019002473A (es) | 2016-09-01 | 2019-09-18 | Mayo Found Medical Education & Res | Métodos y composiciones para el direccionamiento de cánceres de células t. |
| US11590098B2 (en) | 2016-09-06 | 2023-02-28 | Mayo Foundation For Medical Education And Research | Methods of treating triple-negative breast cancer using compositions of antibodies and carrier proteins |
| CA3035653A1 (en) | 2016-09-06 | 2018-03-15 | Mayo Foundation For Medical Education And Research | Paclitaxel-albumin-binding agent compositions and methods for using and making the same |
| CA3035655A1 (en) | 2016-09-06 | 2018-03-15 | Mayo Foundation For Medical Education And Research | Methods of treating pd-l1 expressing cancer |
| US10450340B2 (en) * | 2017-02-16 | 2019-10-22 | Monopar Therapeutics Inc. | 3′-deamino-3′-(2″-pyrroline-1″-yl)-5-imino-13-deoxyanthracyclines and methods of preparation |
| RU2764724C2 (ru) * | 2017-03-16 | 2022-01-19 | ЭИСАЙ Р энд Д МЕНЕДЖМЕНТ КО., ЛТД. | Комбинированная терапия для лечения рака молочной железы |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1098211B (it) * | 1978-05-09 | 1985-09-07 | Farmaceutici Italia | Deossiantracicline antitumorali |
| US5948896A (en) | 1997-08-13 | 1999-09-07 | Gem Pharmaceuticals | Processes for preparing 13-deoxy anthracycline derivatives |
| US5942605A (en) | 1998-03-03 | 1999-08-24 | Gem Pharmaceuticals, Inc. | 5-imino-13-deoxy anthracycline derivatives, their uses, and processes for preparing them |
| PL350042A1 (en) | 1999-01-13 | 2002-10-21 | Genentech Inc | Serine protease inhibitors |
| GB9909925D0 (en) | 1999-04-29 | 1999-06-30 | Pharmacia & Upjohn Spa | Combined preparations comprising anthracycline derivatives |
| GB0003201D0 (en) * | 2000-02-11 | 2000-04-05 | Pharmacia & Upjohn Spa | Method to potentiate the therapeutic efficacy of taxane and derivatives thereof |
| MXPA04010640A (es) * | 2002-05-17 | 2005-08-16 | Aventis Pharma Sa | Uso de docetaxel/doxorrubicina/ciclofosfamida en la terapia adyuvante de cancer de mama y ovario. |
| US9904704B2 (en) | 2014-04-22 | 2018-02-27 | Openx Software Limited | System and method for controlling audience data and tracking |
-
2006
- 2006-04-21 US US11/408,000 patent/US7776832B2/en active Active
-
2007
- 2007-04-23 ES ES07761129T patent/ES2840977T3/es active Active
- 2007-04-23 MY MYPI20084183A patent/MY148571A/en unknown
- 2007-04-23 CN CNA2007800143431A patent/CN101426509A/zh active Pending
- 2007-04-23 UA UAA200813376A patent/UA90597C2/ru unknown
- 2007-04-23 PT PT77611291T patent/PT2010191T/pt unknown
- 2007-04-23 CA CA2649753A patent/CA2649753C/en active Active
- 2007-04-23 WO PCT/US2007/067225 patent/WO2007124489A2/en not_active Ceased
- 2007-04-23 NZ NZ572012A patent/NZ572012A/en not_active IP Right Cessation
- 2007-04-23 PL PL07761129T patent/PL2010191T3/pl unknown
- 2007-04-23 MX MX2008013546A patent/MX2008013546A/es unknown
- 2007-04-23 JP JP2009506812A patent/JP5011377B2/ja not_active Expired - Fee Related
- 2007-04-23 KR KR1020087027728A patent/KR101514336B1/ko not_active Expired - Fee Related
- 2007-04-23 RU RU2008141682/15A patent/RU2421224C2/ru not_active IP Right Cessation
- 2007-04-23 DK DK07761129.1T patent/DK2010191T3/da active
- 2007-04-23 AU AU2007240264A patent/AU2007240264B2/en not_active Ceased
- 2007-04-23 EP EP07761129.1A patent/EP2010191B1/en active Active
-
2008
- 2008-10-12 IL IL194707A patent/IL194707A/en active IP Right Grant
- 2008-10-17 ZA ZA200808892A patent/ZA200808892B/xx unknown
- 2008-10-21 CO CO08112386A patent/CO6190526A2/es not_active Application Discontinuation
-
2010
- 2010-08-17 US US12/857,852 patent/US8158591B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US7776832B2 (en) | 2010-08-17 |
| CA2649753C (en) | 2011-09-27 |
| ES2840977T3 (es) | 2021-07-07 |
| PT2010191T (pt) | 2021-01-04 |
| IL194707A (en) | 2015-10-29 |
| CO6190526A2 (es) | 2010-08-19 |
| KR20090010981A (ko) | 2009-01-30 |
| EP2010191A4 (en) | 2010-05-26 |
| PL2010191T3 (pl) | 2021-05-04 |
| IL194707A0 (en) | 2009-08-03 |
| WO2007124489A3 (en) | 2008-10-23 |
| AU2007240264A1 (en) | 2007-11-01 |
| DK2010191T3 (da) | 2020-12-14 |
| EP2010191A2 (en) | 2009-01-07 |
| ZA200808892B (en) | 2009-10-28 |
| CA2649753A1 (en) | 2007-11-01 |
| EP2010191B1 (en) | 2020-10-07 |
| MX2008013546A (es) | 2009-01-20 |
| RU2421224C2 (ru) | 2011-06-20 |
| KR101514336B1 (ko) | 2015-04-22 |
| BRPI0711256A2 (pt) | 2011-08-30 |
| US20100311679A1 (en) | 2010-12-09 |
| UA90597C2 (ru) | 2010-05-11 |
| MY148571A (en) | 2013-04-30 |
| US20070249547A1 (en) | 2007-10-25 |
| WO2007124489A2 (en) | 2007-11-01 |
| JP2009534426A (ja) | 2009-09-24 |
| CN101426509A (zh) | 2009-05-06 |
| US8158591B2 (en) | 2012-04-17 |
| RU2008141682A (ru) | 2010-05-27 |
| AU2007240264B2 (en) | 2012-11-01 |
| JP5011377B2 (ja) | 2012-08-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 23 APR 2017 BY CPA GLOBAL Effective date: 20140417 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 23 APR 2018 BY CPA GLOBAL Effective date: 20170311 |
|
| LAPS | Patent lapsed |