NZ550284A - Multiple promoter expression cassettes for simultaneous delivery of RNAi agents - Google Patents

Multiple promoter expression cassettes for simultaneous delivery of RNAi agents

Info

Publication number
NZ550284A
NZ550284A NZ550284A NZ55028405A NZ550284A NZ 550284 A NZ550284 A NZ 550284A NZ 550284 A NZ550284 A NZ 550284A NZ 55028405 A NZ55028405 A NZ 55028405A NZ 550284 A NZ550284 A NZ 550284A
Authority
NZ
New Zealand
Prior art keywords
rnai
promoter
expression
sequences
viral
Prior art date
Application number
NZ550284A
Other languages
English (en)
Inventor
David A Suhy
Petrus W Roelvink
Alexander A Kolykhalov
Original Assignee
Benitec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Benitec Ltd filed Critical Benitec Ltd
Publication of NZ550284A publication Critical patent/NZ550284A/en

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C12N15/111—General methods applicable to biologically active non-coding nucleic acids
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/53—Physical structure partially self-complementary or closed
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2330/00—Production
    • C12N2330/30—Production chemically synthesised

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  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NZ550284A 2004-03-05 2005-03-04 Multiple promoter expression cassettes for simultaneous delivery of RNAi agents NZ550284A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US55050404P 2004-03-05 2004-03-05
US55392004P 2004-03-17 2004-03-17
PCT/US2005/007447 WO2005087926A2 (en) 2004-03-05 2005-03-04 Multiple promoter expression cassettes for simultaneous delivery of rnai agents

Publications (1)

Publication Number Publication Date
NZ550284A true NZ550284A (en) 2009-04-30

Family

ID=34963938

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ550284A NZ550284A (en) 2004-03-05 2005-03-04 Multiple promoter expression cassettes for simultaneous delivery of RNAi agents

Country Status (13)

Country Link
US (3) US7727970B2 (enExample)
EP (2) EP2363483A3 (enExample)
JP (1) JP4763681B2 (enExample)
KR (2) KR101246862B1 (enExample)
CN (1) CN103060324B (enExample)
AT (1) ATE508190T1 (enExample)
AU (1) AU2005222084B2 (enExample)
CA (1) CA2558771C (enExample)
DE (1) DE602005027820D1 (enExample)
DK (1) DK1725660T3 (enExample)
IL (1) IL177862A (enExample)
NZ (1) NZ550284A (enExample)
WO (1) WO2005087926A2 (enExample)

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US20050197313A1 (en) 2005-09-08
CN103060324A (zh) 2013-04-24
US8691967B2 (en) 2014-04-08
KR101337579B1 (ko) 2013-12-06
WO2005087926A2 (en) 2005-09-22
AU2005222084A1 (en) 2005-09-22
DK1725660T3 (da) 2011-08-29
EP1725660B1 (en) 2011-05-04
US8283461B2 (en) 2012-10-09
ATE508190T1 (de) 2011-05-15
WO2005087926A3 (en) 2006-03-16
US20130171726A1 (en) 2013-07-04
DE602005027820D1 (de) 2011-06-16
JP2007527244A (ja) 2007-09-27
AU2005222084B2 (en) 2010-04-22
CA2558771C (en) 2013-01-08
KR20120008094A (ko) 2012-01-25
JP4763681B2 (ja) 2011-08-31
CA2558771A1 (en) 2005-09-22
EP1725660A2 (en) 2006-11-29
EP2363483A2 (en) 2011-09-07
IL177862A0 (en) 2006-12-31
IL177862A (en) 2014-05-28
CN103060324B (zh) 2015-04-01
US20110003378A1 (en) 2011-01-06
EP2363483A3 (en) 2014-07-16
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US7727970B2 (en) 2010-06-01

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