NZ538346A - Use of antiprogestins for prophylaxis and treatment of hormone-dependent diseases - Google Patents

Use of antiprogestins for prophylaxis and treatment of hormone-dependent diseases

Info

Publication number
NZ538346A
NZ538346A NZ538346A NZ53834601A NZ538346A NZ 538346 A NZ538346 A NZ 538346A NZ 538346 A NZ538346 A NZ 538346A NZ 53834601 A NZ53834601 A NZ 53834601A NZ 538346 A NZ538346 A NZ 538346A
Authority
NZ
New Zealand
Prior art keywords
antiprogestin
antiestrogen
treatment
breast cancer
cancer
Prior art date
Application number
NZ538346A
Other languages
English (en)
Inventor
Jens Hoffmann
Rosemarie Lichtner
Gerhard Siemeister
Martin Schneider
Ulrike Fuhrmann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NZ538346A publication Critical patent/NZ538346A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NZ538346A 2000-10-18 2001-10-17 Use of antiprogestins for prophylaxis and treatment of hormone-dependent diseases NZ538346A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24099800P 2000-10-18 2000-10-18
EP00250341 2000-10-18

Publications (1)

Publication Number Publication Date
NZ538346A true NZ538346A (en) 2007-03-30

Family

ID=26072951

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ538346A NZ538346A (en) 2000-10-18 2001-10-17 Use of antiprogestins for prophylaxis and treatment of hormone-dependent diseases

Country Status (26)

Country Link
US (1) US7378406B2 (https=)
EP (1) EP1328276B1 (https=)
JP (2) JP2004511522A (https=)
KR (1) KR100632908B1 (https=)
CN (1) CN1512886A (https=)
AT (1) ATE310522T1 (https=)
AU (2) AU1824302A (https=)
BG (1) BG107743A (https=)
BR (1) BR0114665A (https=)
CA (1) CA2423017C (https=)
CY (1) CY1104981T1 (https=)
CZ (1) CZ299942B6 (https=)
DE (1) DE60115274T2 (https=)
DK (1) DK1328276T3 (https=)
EE (1) EE05259B1 (https=)
ES (1) ES2253443T3 (https=)
HR (1) HRP20030387A2 (https=)
HU (1) HUP0301460A3 (https=)
IL (2) IL154975A0 (https=)
MX (1) MXPA03002954A (https=)
NO (1) NO20031740L (https=)
NZ (1) NZ538346A (https=)
PL (1) PL360151A1 (https=)
SI (1) SI1328276T1 (https=)
SK (1) SK287124B6 (https=)
WO (1) WO2002032430A1 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY27301A1 (es) * 2001-05-25 2003-02-28 Schering Ag Uso y composiciones de antiprogestinas para el tratamiento de enfermedades de la próstata
DE10159217A1 (de) 2001-11-27 2003-06-05 Schering Ag 17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate
US20040242551A1 (en) * 2003-05-28 2004-12-02 Schering Ag Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases
US9517240B2 (en) * 2006-09-26 2016-12-13 The Regents Of The University Of California Methods and compositions for cancer prevention and treatment
US20080261929A1 (en) * 2007-04-23 2008-10-23 Jens Hoffmann Combination of progesterone-receptor antagonist together with an aromatase inhibitor for use in brca mediated diseases
EP2136796A2 (en) * 2007-04-23 2009-12-30 Bayer Schering Pharma Aktiengesellschaft Progesterone-receptor antagonist for use in brca-mediated cancer alone or as combination with antiestrogen
US20080268041A1 (en) * 2007-04-23 2008-10-30 Jens Hoffmann Combination of progesterone-receptor antagonist together with none-steroidal antiestrogen for use in brca mediated diseases
TWI539953B (zh) * 2008-04-28 2016-07-01 瑞波若斯治療學公司 用於治療乳癌之組成物和方法
TWI477276B (zh) * 2008-04-28 2015-03-21 Repros Therapeutics Inc 抗黃體素給藥方案
DE102009034366A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034367A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034368A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034362A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034526A1 (de) 2009-07-21 2011-02-10 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034525A1 (de) 2009-07-21 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102010007719A1 (de) 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
DE102010007722A1 (de) 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
EP3865502A1 (en) * 2010-03-22 2021-08-18 Allergan Pharmaceuticals International Limited Compositions and methods for non-toxic delivery of cdb-2914
SG11201407397WA (en) 2012-05-31 2014-12-30 Repros Therapeutics Inc Formulations and methods for vaginal delivery of antiprogestins
ES2688821T3 (es) 2012-11-02 2018-11-07 Repros Therapeutics Inc. Métodos y composiciones para tratar afecciones dependientes de la progesterona

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3733478A1 (de) * 1987-10-01 1989-04-13 Schering Ag Antigestagen- und antioestrogenwirksame verbindungen zur geburtseinleitung und zum schwangerschaftsabbruch sowie zur behandlung gynaekologischer stoerungen und hormonabhaengiger tumore
DE19706061A1 (de) 1997-02-07 1998-08-13 Schering Ag Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette

Also Published As

Publication number Publication date
JP2010077158A (ja) 2010-04-08
IL154975A (en) 2007-05-15
EP1328276A1 (en) 2003-07-23
SK287124B6 (sk) 2009-12-07
BR0114665A (pt) 2004-01-13
CA2423017A1 (en) 2002-04-25
SI1328276T1 (sl) 2006-04-30
IL154975A0 (en) 2003-10-31
CZ299942B6 (cs) 2008-12-29
JP2004511522A (ja) 2004-04-15
ATE310522T1 (de) 2005-12-15
EE05259B1 (et) 2010-02-15
KR20030044007A (ko) 2003-06-02
HRP20030387A2 (en) 2005-04-30
DK1328276T3 (da) 2006-04-03
HUP0301460A2 (hu) 2003-10-28
KR100632908B1 (ko) 2006-10-13
CY1104981T1 (el) 2010-03-03
CN1512886A (zh) 2004-07-14
NO20031740D0 (no) 2003-04-15
CA2423017C (en) 2009-01-06
DE60115274T2 (de) 2006-07-27
US20040048841A1 (en) 2004-03-11
AU1824302A (en) 2002-04-29
PL360151A1 (en) 2004-09-06
AU2002218243B2 (en) 2006-07-13
MXPA03002954A (es) 2003-08-07
EP1328276B1 (en) 2005-11-23
HUP0301460A3 (en) 2010-01-28
US7378406B2 (en) 2008-05-27
NO20031740L (no) 2003-06-17
EE200300155A (et) 2003-08-15
BG107743A (bg) 2004-01-30
DE60115274D1 (de) 2005-12-29
SK4742003A3 (en) 2004-09-08
ES2253443T3 (es) 2006-06-01
WO2002032430A1 (en) 2002-04-25

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AU2002218243A1 (en) Use of antiprogestins for prophylaxis and treatment of hormone-dependent diseases
US20070238714A1 (en) Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases
AU2002223619B2 (en) Use of antiprogestins for the induction of apoptosis in a cell
AU2002223619A1 (en) Use of antiprogestins for the induction of apoptosis in a cell
US20040072811A1 (en) Use of antiprogestins for the induction of apoptosis in a cell
ZA200303793B (en) Use of antiprogestins for prophylaxis and treatment of hormone-dependent diseases.
US20080268041A1 (en) Combination of progesterone-receptor antagonist together with none-steroidal antiestrogen for use in brca mediated diseases
US20080261929A1 (en) Combination of progesterone-receptor antagonist together with an aromatase inhibitor for use in brca mediated diseases
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Legal Events

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