NZ530604A - Pharmaceutical preparations comprising ion exchange resins with active substance loading - Google Patents
Pharmaceutical preparations comprising ion exchange resins with active substance loadingInfo
- Publication number
- NZ530604A NZ530604A NZ530604A NZ53060402A NZ530604A NZ 530604 A NZ530604 A NZ 530604A NZ 530604 A NZ530604 A NZ 530604A NZ 53060402 A NZ53060402 A NZ 53060402A NZ 530604 A NZ530604 A NZ 530604A
- Authority
- NZ
- New Zealand
- Prior art keywords
- ion exchanger
- pharmaceutical preparation
- active substance
- loaded
- preparation according
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title claims abstract description 35
- 239000000825 pharmaceutical preparation Substances 0.000 title claims abstract description 20
- 239000003456 ion exchange resin Substances 0.000 title description 15
- 229920003303 ion-exchange polymer Polymers 0.000 title description 15
- 238000011068 loading method Methods 0.000 title description 3
- 150000002500 ions Chemical class 0.000 claims abstract description 41
- 239000002245 particle Substances 0.000 claims abstract description 31
- 150000001768 cations Chemical class 0.000 claims abstract description 9
- 239000000725 suspension Substances 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 229920001429 chelating resin Polymers 0.000 claims description 9
- 230000002378 acidificating effect Effects 0.000 claims description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 5
- 239000011324 bead Substances 0.000 claims description 5
- 239000008213 purified water Substances 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- SPFYMRJSYKOXGV-UHFFFAOYSA-N Baytril Chemical compound C1CN(CC)CCN1C(C(=C1)F)=CC2=C1C(=O)C(C(O)=O)=CN2C1CC1 SPFYMRJSYKOXGV-UHFFFAOYSA-N 0.000 claims description 3
- 229960000740 enrofloxacin Drugs 0.000 claims description 3
- 230000007935 neutral effect Effects 0.000 claims description 3
- 229910002016 Aerosil® 200 Inorganic materials 0.000 claims description 2
- 239000013020 final formulation Substances 0.000 claims description 2
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- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 1
- KYGZCKSPAKDVKC-UHFFFAOYSA-N Oxolinic acid Chemical group C1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC2=C1OCO2 KYGZCKSPAKDVKC-UHFFFAOYSA-N 0.000 claims 1
- 239000003306 quinoline derived antiinfective agent Substances 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- -1 cation ion Chemical group 0.000 abstract description 15
- 238000002360 preparation method Methods 0.000 description 18
- 239000000203 mixture Substances 0.000 description 16
- 239000000126 substance Substances 0.000 description 16
- 238000000227 grinding Methods 0.000 description 15
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 description 14
- 241001465754 Metazoa Species 0.000 description 13
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- 235000002639 sodium chloride Nutrition 0.000 description 6
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
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- GSDSWSVVBLHKDQ-UHFFFAOYSA-N 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid Chemical compound FC1=CC(C(C(C(O)=O)=C2)=O)=C3N2C(C)COC3=C1N1CCN(C)CC1 GSDSWSVVBLHKDQ-UHFFFAOYSA-N 0.000 description 2
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- 239000004322 Butylated hydroxytoluene Substances 0.000 description 2
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 2
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- LOUPRKONTZGTKE-WZBLMQSHSA-N Quinine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-WZBLMQSHSA-N 0.000 description 2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10134719A DE10134719A1 (de) | 2001-07-17 | 2001-07-17 | Pharmazeutische Zubereitungen enthaltend wirkstoffbeladene Ionentauscherharze |
| PCT/EP2002/007417 WO2003007995A2 (de) | 2001-07-17 | 2002-07-04 | Pharmazeutische zubereitungen enthaltend fluorochinolonbeladene ionentauscherharze |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ530604A true NZ530604A (en) | 2006-09-29 |
Family
ID=7692081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ530604A NZ530604A (en) | 2001-07-17 | 2002-07-04 | Pharmaceutical preparations comprising ion exchange resins with active substance loading |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20040247560A1 (https=) |
| EP (1) | EP1411894A2 (https=) |
| JP (1) | JP2005500332A (https=) |
| AR (1) | AR034777A1 (https=) |
| AU (1) | AU2002345086B2 (https=) |
| BR (1) | BR0211149A (https=) |
| CA (1) | CA2453616A1 (https=) |
| DE (1) | DE10134719A1 (https=) |
| MX (1) | MXPA04000332A (https=) |
| NO (1) | NO20040205L (https=) |
| NZ (1) | NZ530604A (https=) |
| WO (1) | WO2003007995A2 (https=) |
| ZA (1) | ZA200400269B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10224086A1 (de) * | 2002-05-31 | 2003-12-11 | Bayer Ag | Pharmazeutische Zubereitungen zur oralen Anwendung enthaltend wirkstoffbeladene Ionentauscherharze sowie strukturviskose Gelbildner als Verdicker |
| DE102006049520A1 (de) | 2006-10-20 | 2008-04-24 | Bayer Healthcare Ag | Verfahren zur Herstellung von Pradofloxacin |
| EP2343089A4 (en) | 2008-09-23 | 2013-05-01 | Jaer S A Lab | USE OF XYLITOL OR DERIVATIVES THEREOF FOR MASKING THE TASTE OF CHEMOTHERAPEUTIC MEDICAMENTS OF THE CHINOLO-N-NAPHTHYRIDONE-CARBOXYLIC ACID GROUP FOR PIG DICULTINATION |
| DE102012021559A1 (de) | 2012-11-02 | 2014-05-08 | Technische Universität Bergakademie Freiberg | Verfahren zur Herstellung von submikronen makroporösen Ionenaustauschermaterialien durch mechansiche Zerkleinerung |
| US9669010B2 (en) | 2012-12-06 | 2017-06-06 | Bio Health Solutions, Llc | Treatment for chronic kidney disease |
| DK2928461T3 (da) * | 2012-12-06 | 2019-11-25 | Bio Health Solutions Llc | Behandling til kronisk nyresygdom |
| EP2808319A1 (en) * | 2013-05-31 | 2014-12-03 | Arevipharma GmbH | 3-[3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex |
| CA3098060A1 (en) | 2018-04-25 | 2019-10-31 | Bayer Animal Health Gmbh | Process for the hydrolysis of quinolone carboxylic esters |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA804914B (en) * | 1979-08-29 | 1981-08-26 | Rohm & Haas | The production of powdered resin and the powdered resin so produced |
| DE3719764A1 (de) * | 1987-06-13 | 1988-12-22 | Bayer Ag | Ionenaustauscherharze beladen mit chinoloncarbonsaeurederivaten, ihre herstellung und verwendung |
-
2001
- 2001-07-17 DE DE10134719A patent/DE10134719A1/de not_active Withdrawn
-
2002
- 2002-07-04 BR BR0211149-7A patent/BR0211149A/pt not_active IP Right Cessation
- 2002-07-04 NZ NZ530604A patent/NZ530604A/en unknown
- 2002-07-04 JP JP2003513600A patent/JP2005500332A/ja not_active Withdrawn
- 2002-07-04 US US10/483,635 patent/US20040247560A1/en not_active Abandoned
- 2002-07-04 AU AU2002345086A patent/AU2002345086B2/en not_active Ceased
- 2002-07-04 MX MXPA04000332A patent/MXPA04000332A/es not_active Application Discontinuation
- 2002-07-04 WO PCT/EP2002/007417 patent/WO2003007995A2/de not_active Ceased
- 2002-07-04 CA CA002453616A patent/CA2453616A1/en not_active Abandoned
- 2002-07-04 EP EP02743262A patent/EP1411894A2/de not_active Ceased
- 2002-07-12 AR ARP020102629A patent/AR034777A1/es not_active Application Discontinuation
-
2004
- 2004-01-14 ZA ZA2004/00269A patent/ZA200400269B/en unknown
- 2004-01-16 NO NO20040205A patent/NO20040205L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BR0211149A (pt) | 2004-06-29 |
| CA2453616A1 (en) | 2003-01-30 |
| EP1411894A2 (de) | 2004-04-28 |
| ZA200400269B (en) | 2005-03-30 |
| AU2002345086B2 (en) | 2007-05-24 |
| US20040247560A1 (en) | 2004-12-09 |
| DE10134719A1 (de) | 2003-02-06 |
| WO2003007995A2 (de) | 2003-01-30 |
| WO2003007995A3 (de) | 2003-07-31 |
| JP2005500332A (ja) | 2005-01-06 |
| MXPA04000332A (es) | 2005-04-19 |
| NO20040205L (no) | 2004-01-16 |
| AR034777A1 (es) | 2004-03-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |