NZ513502A - A method for introducing a nucleic acid into a mammalian neural stem cell or progenitor cell via the inherent transport mechanism of the cell - Google Patents

A method for introducing a nucleic acid into a mammalian neural stem cell or progenitor cell via the inherent transport mechanism of the cell

Info

Publication number
NZ513502A
NZ513502A NZ513502A NZ51350200A NZ513502A NZ 513502 A NZ513502 A NZ 513502A NZ 513502 A NZ513502 A NZ 513502A NZ 51350200 A NZ51350200 A NZ 51350200A NZ 513502 A NZ513502 A NZ 513502A
Authority
NZ
New Zealand
Prior art keywords
cell
nucleic acid
introducing
transport mechanism
neural stem
Prior art date
Application number
NZ513502A
Inventor
Peter Eriksson
Owe Orwar
Original Assignee
A & Science Invest Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A & Science Invest Ab filed Critical A & Science Invest Ab
Publication of NZ513502A publication Critical patent/NZ513502A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

A method for introducing a substance comprising a nucleic acid into a mammalian neural stem cell or progenitor cell, wherein the nucleic acid directly interacts with the cell membrane of the cell or a component within the cell membrane in vitro whereby the substance comprising the nucleic acid is taken up by the cell via the inherent transport mechanism of the cell, is disclosed. Also different applications of said method are disclosed.
NZ513502A 1999-01-15 2000-01-14 A method for introducing a nucleic acid into a mammalian neural stem cell or progenitor cell via the inherent transport mechanism of the cell NZ513502A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9900134A SE9900134D0 (en) 1999-01-15 1999-01-15 A method for introducing substances into cells, and using said method
PCT/SE2000/000073 WO2000042202A1 (en) 1999-01-15 2000-01-14 A method for introducing substances into cells, and use of said method

Publications (1)

Publication Number Publication Date
NZ513502A true NZ513502A (en) 2003-03-28

Family

ID=20414133

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ513502A NZ513502A (en) 1999-01-15 2000-01-14 A method for introducing a nucleic acid into a mammalian neural stem cell or progenitor cell via the inherent transport mechanism of the cell

Country Status (10)

Country Link
EP (1) EP1141340A1 (en)
JP (1) JP2002534126A (en)
CN (1) CN1179047C (en)
AU (1) AU751342B2 (en)
CA (1) CA2359349A1 (en)
IL (1) IL144104A0 (en)
NZ (1) NZ513502A (en)
SE (1) SE9900134D0 (en)
WO (1) WO2000042202A1 (en)
ZA (1) ZA200105749B (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750376A (en) * 1991-07-08 1998-05-12 Neurospheres Holdings Ltd. In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
SG54115A1 (en) * 1993-04-27 1998-11-16 Gerber Scient Products Inc Thermal printing apparatus with improved power supply
WO1996015811A1 (en) * 1994-11-17 1996-05-30 Imperial College Of Science, Technology & Medicine Internalisation of dna, using conjugates of poly-l-lysine and an integrin receptor ligand
US5753506A (en) * 1996-05-23 1998-05-19 Cns Stem Cell Technology, Inc. Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals

Also Published As

Publication number Publication date
CN1179047C (en) 2004-12-08
SE9900134D0 (en) 1999-01-15
CN1336959A (en) 2002-02-20
JP2002534126A (en) 2002-10-15
WO2000042202A1 (en) 2000-07-20
AU2337200A (en) 2000-08-01
AU751342B2 (en) 2002-08-15
IL144104A0 (en) 2002-05-23
ZA200105749B (en) 2004-01-12
EP1141340A1 (en) 2001-10-10
CA2359349A1 (en) 2000-07-20

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Legal Events

Date Code Title Description
ASS Change of ownership

Owner name: CELL THERAPEUTICS SCANDINAVIA AB, SE

Free format text: OLD OWNER(S): A + SCIENCE INVEST AB

PSEA Patent sealed
RENW Renewal (renewal fees accepted)
ASS Change of ownership

Owner name: CELLARTIS AB, SE

Free format text: OLD OWNER(S): CELL THERAPEUTICS SCANDINAVIA AB