NZ510359A - Amelioration of apomorphine adverse effects for sexual dysfunction in males and females - Google Patents
Amelioration of apomorphine adverse effects for sexual dysfunction in males and femalesInfo
- Publication number
- NZ510359A NZ510359A NZ510359A NZ51035999A NZ510359A NZ 510359 A NZ510359 A NZ 510359A NZ 510359 A NZ510359 A NZ 510359A NZ 51035999 A NZ51035999 A NZ 51035999A NZ 510359 A NZ510359 A NZ 510359A
- Authority
- NZ
- New Zealand
- Prior art keywords
- apomorphine
- patient
- dose
- adverse effects
- sexual dysfunction
- Prior art date
Links
- VMWNQDUVQKEIOC-CYBMUJFWSA-N apomorphine Chemical compound C([C@H]1N(C)CC2)C3=CC=C(O)C(O)=C3C3=C1C2=CC=C3 VMWNQDUVQKEIOC-CYBMUJFWSA-N 0.000 title abstract 7
- 229960004046 apomorphine Drugs 0.000 title abstract 7
- 201000001880 Sexual dysfunction Diseases 0.000 title abstract 2
- 230000002411 adverse Effects 0.000 title abstract 2
- 230000000694 effects Effects 0.000 title abstract 2
- 231100000872 sexual dysfunction Toxicity 0.000 title abstract 2
- 238000011287 therapeutic dose Methods 0.000 abstract 3
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
- 230000018052 penile erection Effects 0.000 abstract 1
- 230000000737 periodic effect Effects 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Psychology (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/138,982 US5994363A (en) | 1998-08-24 | 1998-08-24 | Amelioration of apomorphine adverse effects |
| PCT/US1999/014965 WO2000010567A1 (en) | 1998-08-24 | 1999-07-01 | Amelioration of apomorphine adverse effects |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ510359A true NZ510359A (en) | 2003-06-30 |
Family
ID=22484576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ510359A NZ510359A (en) | 1998-08-24 | 1999-07-01 | Amelioration of apomorphine adverse effects for sexual dysfunction in males and females |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5994363A (enExample) |
| EP (1) | EP1105129A4 (enExample) |
| JP (1) | JP2002523370A (enExample) |
| CN (1) | CN1212841C (enExample) |
| AU (1) | AU764068B2 (enExample) |
| BR (1) | BR9913235A (enExample) |
| CA (1) | CA2341673A1 (enExample) |
| CZ (1) | CZ2001610A3 (enExample) |
| HU (1) | HUP0201212A3 (enExample) |
| IL (1) | IL141512A0 (enExample) |
| NO (1) | NO20010899L (enExample) |
| NZ (1) | NZ510359A (enExample) |
| PL (1) | PL346273A1 (enExample) |
| WO (1) | WO2000010567A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050065161A1 (en) * | 1996-02-02 | 2005-03-24 | Nitromed, Inc. | Nitrosated and nitrosylated alpha-adrenergic receptor antagonist compounds, compositions and their uses |
| US6472425B1 (en) | 1997-10-31 | 2002-10-29 | Nitromed, Inc. | Methods for treating female sexual dysfunctions |
| BR0005797A (pt) * | 2000-03-20 | 2001-10-16 | Abbott Lab | Métodos para o tratamento de disfunção sexual com apomorfina em nìveis de concentração plasmática especificados |
| IL151614A0 (en) | 2000-04-07 | 2003-04-10 | Tap Holdings Inc | Apomorphine derivatives and methods for their use |
| EP1284653B1 (en) * | 2000-05-09 | 2007-11-28 | Nitromed, Inc. | Infrared thermography and treatment of sexual dysfunctions |
| DE10053397A1 (de) | 2000-10-20 | 2002-05-02 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
| DE10043321B4 (de) * | 2000-08-24 | 2005-07-28 | Neurobiotec Gmbh | Verwendung eines transdermalen therapeutischen Systems zur Behandlung der Parkinsonschen Krankheit, zur Behandlung und Prävention des prämenstruellen Syndroms und zur Lactationshemmung |
| WO2002062315A1 (en) * | 2001-02-08 | 2002-08-15 | Pharmacia Corporation | Rapid-onset medicament for the treatment of sexual dysfunction |
| ES2180446B1 (es) * | 2001-07-02 | 2004-01-16 | Esteve Labor Dr | Empleo de derivados de acidos 2,5-dihidroxibencenosulfonicos en la elaboracion de un medicamento para potenciar el efecto de otros farmacos en el tratamiento de la disfuncion erectil. |
| KR100666520B1 (ko) * | 2002-02-07 | 2007-01-11 | 파마시아 코포레이션 | 점막 송달을 위한 약제학적 투약형 |
| EP1496915A1 (en) * | 2002-03-19 | 2005-01-19 | Brain 'N' Beyond Biotech | Glycoside and orthoester glycoside derivatives of apomorphine, analogs, and uses thereof |
| NZ536965A (en) * | 2002-05-31 | 2007-02-23 | Titan Pharmaceuticals Inc | Nonerodible polymeric matrix with buprenorphine encapsulated for the treatment of opiate addiction and pain |
| AU2003284005B2 (en) * | 2002-10-03 | 2009-12-17 | Forest Laboratories Holdings Limited | Dosage escalation and divided daily dose of anti-depressants to treat neurological disorders |
| MXPA05010450A (es) | 2003-03-31 | 2005-11-04 | Titan Pharmaceuticals Inc | Dispositivo polimerico implantable para la liberacion prolongada de agonistas de dopamina. |
| US20040204439A1 (en) * | 2003-04-14 | 2004-10-14 | Staniforth John Nicholas | Composition, device, and method for treating sexual dysfunction via inhalation |
| AU2004228757A1 (en) * | 2003-04-14 | 2004-10-21 | Vectura Ltd | Pharmaceutical compositions comprising apomorphine for pulmonary inhalation |
| CA2562465A1 (en) * | 2004-04-13 | 2005-10-27 | The Mclean Hospital Corporation | R(-)-11-hydroxyaporphine derivatives and uses thereof |
| US20060083724A1 (en) * | 2004-10-01 | 2006-04-20 | Hilst Todd W | Compositions for the treatment of femal sexual dysfunction |
| US7994220B2 (en) | 2005-09-28 | 2011-08-09 | Cypress Bioscience, Inc. | Milnacipran for the long-term treatment of fibromyalgia syndrome |
| WO2009003147A1 (en) * | 2007-06-26 | 2008-12-31 | Parkinson's Institute | Methods and compositions for the treatment of neurological disorders |
| US8431591B2 (en) * | 2007-07-12 | 2013-04-30 | The Mclean Hospital Corporation | R(−)-2-methoxy-11-hydroxyaporphine and derivatives thereof |
| GB0721394D0 (en) * | 2007-10-31 | 2007-12-12 | Vectura Group Plc | Compositions for trating parkinson's disease |
| PL2952191T3 (pl) | 2009-06-12 | 2019-02-28 | Sunovion Pharmaceuticals Inc. | Apomorfina w postaci do podawania podjęzykowego |
| CN103476372B (zh) | 2010-12-16 | 2016-04-27 | Cynapsus疗法有限公司 | 舌下薄膜 |
| EP2545905A1 (en) * | 2011-07-11 | 2013-01-16 | Britannia Pharmaceuticals Limited | A new therapeutical composition containing apomorphine as active ingredient |
| ES3015535T3 (en) | 2015-04-21 | 2025-05-06 | Sumitomo Pharma America Inc | Methods of treating parkinson's disease by administration of apomorphine to an oral mucosa |
| IT202100009857A1 (it) | 2021-04-19 | 2022-10-19 | Univ Degli Studi Di Torino | Formulazione a rilascio controllato e prolungato di apomorfina |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2818855A (en) * | 1954-02-11 | 1958-01-07 | Anthony P Miller | Surgical device |
| US3976780A (en) * | 1968-07-29 | 1976-08-24 | Societe D'etudes Scientifiques Et Industrielles L'ile-De-France | Methods of protection against emesis in mammals by administration of a 3-alkoxy-thianaphthene-2-carboxamide |
| US4127118B1 (en) * | 1977-03-16 | 1995-12-19 | Alvaro Latorre | Method of effecting and enhancing an erection |
| US4543256A (en) * | 1982-03-17 | 1985-09-24 | Northeastern University | (-)-10,1L Methylenedioxy-N-N-propylnoraporphine and methods employing it for inhibiting the effects of epileptic seizures and for prevention and treatment of duodenal ulcers |
| AU1508183A (en) * | 1982-06-04 | 1983-12-08 | Beecham Group Plc | Benzamide and anilide derivatives of 8-azabicyclo-(3.2.1)- -octane |
| US4687773A (en) * | 1983-03-28 | 1987-08-18 | Mclean Hospital | (+)-N-N-propylnorapomorphine and selective limbic activity |
| US4521421A (en) * | 1983-09-26 | 1985-06-04 | Eli Lilly And Company | Treatment of sexual dysfunction |
| US4624965A (en) * | 1984-11-15 | 1986-11-25 | Nastech Pharmaceutical Co., Inc. | Novel method of administering anti-nausea and anti-emetic pharmaceutical agents and novel dosage forms containing same |
| US4749700A (en) * | 1984-10-23 | 1988-06-07 | Nastech Pharmaceutical Co, Inc. | Novel methods of administering antihistamines, antinausea and antiemetic pharmaceutical agents and novel dosage forms containing same |
| US4772459A (en) * | 1986-09-09 | 1988-09-20 | Erbamont, Inc. | Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein |
| US4749686A (en) * | 1986-12-04 | 1988-06-07 | New York Medical College | Combinations of renal vasodilators and α1 -adrenergic or ganglionic blocking agents and methods for treating diseases |
| US4801587A (en) * | 1987-03-02 | 1989-01-31 | Gene Voss | Impotence ointment |
| US5102887A (en) * | 1989-02-17 | 1992-04-07 | Arch Development Corporation | Method for reducing emesis and nausea induced by the administration of an emesis causing agent |
| US5242391A (en) * | 1990-04-25 | 1993-09-07 | Alza Corporation | Urethral insert for treatment of erectile dysfunction |
| US5270323A (en) * | 1990-05-31 | 1993-12-14 | Pfizer Inc. | Method of treating impotence |
| US5166145A (en) * | 1990-09-10 | 1992-11-24 | Alza Corporation | Antiemetic therapy |
| DE69514794T2 (de) * | 1994-04-22 | 2000-07-27 | Pentech Pharmaceuticals, Inc. | Sublinguale dosierungsformen enthaltend apomorphin zur verwendung bei der behandlung von erektiler dysfunktion |
| US5562917A (en) * | 1994-12-23 | 1996-10-08 | Pentech Pharmaceuticals, Inc. | Transdermal administration of apomorphine |
-
1998
- 1998-08-24 US US09/138,982 patent/US5994363A/en not_active Expired - Fee Related
-
1999
- 1999-07-01 CA CA002341673A patent/CA2341673A1/en not_active Abandoned
- 1999-07-01 AU AU49651/99A patent/AU764068B2/en not_active Ceased
- 1999-07-01 BR BR9913235-4A patent/BR9913235A/pt not_active IP Right Cessation
- 1999-07-01 WO PCT/US1999/014965 patent/WO2000010567A1/en not_active Ceased
- 1999-07-01 JP JP2000565888A patent/JP2002523370A/ja active Pending
- 1999-07-01 CZ CZ2001610A patent/CZ2001610A3/cs unknown
- 1999-07-01 EP EP99933642A patent/EP1105129A4/en not_active Withdrawn
- 1999-07-01 CN CNB998125210A patent/CN1212841C/zh not_active Expired - Fee Related
- 1999-07-01 HU HU0201212A patent/HUP0201212A3/hu unknown
- 1999-07-01 PL PL99346273A patent/PL346273A1/xx not_active Application Discontinuation
- 1999-07-01 NZ NZ510359A patent/NZ510359A/xx unknown
- 1999-07-01 IL IL14151299A patent/IL141512A0/xx unknown
-
2001
- 2001-02-22 NO NO20010899A patent/NO20010899L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US5994363A (en) | 1999-11-30 |
| CN1324238A (zh) | 2001-11-28 |
| AU4965199A (en) | 2000-03-14 |
| BR9913235A (pt) | 2001-12-04 |
| CZ2001610A3 (cs) | 2002-03-13 |
| CN1212841C (zh) | 2005-08-03 |
| HUP0201212A2 (en) | 2002-08-28 |
| CA2341673A1 (en) | 2000-03-02 |
| IL141512A0 (en) | 2002-03-10 |
| HUP0201212A3 (en) | 2004-12-28 |
| AU764068B2 (en) | 2003-08-07 |
| NO20010899D0 (no) | 2001-02-22 |
| PL346273A1 (en) | 2002-01-28 |
| EP1105129A4 (en) | 2003-11-12 |
| JP2002523370A (ja) | 2002-07-30 |
| NO20010899L (no) | 2001-04-24 |
| WO2000010567A1 (en) | 2000-03-02 |
| EP1105129A1 (en) | 2001-06-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) | ||
| RENW | Renewal (renewal fees accepted) |