NZ504104A - Novel tricyclic compounds and their use in medicine, a process for their preparation, pharmaceutical compositions containing them, and their use in the manufacture of a medicament for treating diseases in which insulin is the underlying pathophysiological mechanism - Google Patents
Novel tricyclic compounds and their use in medicine, a process for their preparation, pharmaceutical compositions containing them, and their use in the manufacture of a medicament for treating diseases in which insulin is the underlying pathophysiological mechanismInfo
- Publication number
- NZ504104A NZ504104A NZ504104A NZ50410498A NZ504104A NZ 504104 A NZ504104 A NZ 504104A NZ 504104 A NZ504104 A NZ 504104A NZ 50410498 A NZ50410498 A NZ 50410498A NZ 504104 A NZ504104 A NZ 504104A
- Authority
- NZ
- New Zealand
- Prior art keywords
- optionally substituted
- group
- represents hydrogen
- hydrogen
- aralkyl
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Novel hypolipidemic, antihyperglycemic compounds of formula (I) and its compositions wherein: R1, R2, R3 and R4 are the same or different and represent hydrogen, halogen, hydroxy, nitro, cyano, formyl or optionally substituted groups as described in the complete specification; Ring A represents a 5-6 membered carbocyclic structure which may optionally be substituted and may be saturated or contain one or more double bonds or may be aromatic; X represents a heteroatom selected from oxygen, sulfur, or NR9 where R9 is hydrogen, alkyl, aryl, aralkyl, acyl, alkoxycarbonyl, aryloxycarbonyl or aralkoxycarbonyl; Ar represents an optionally substituted divalent single or fused aromatic or heterocyclic group; R5 represents hydrogen, hydroxy, alkoxy, halogen, lower alkyl, optionally substituted aralkyl group or forms a bond together with the adjacent R6; R6 represents hydrogen, hydroxy, alkoxy, halogen, lower alkyl group, acyl, optionally substituted aralkyl or forms a bond with R5; R7 represents hydrogen, or a optionally substituted group as described in the complete specification; R8 represents hydrogen or an optionally substituted group as described in the complete specification; Y represents oxygen or NR10 where R10 represents hydrogen, alkyl, aryl, hydroxyalkyl or aralkyl groups or R8 and R10 together form a 5 or 6 membered cyclic structure containing carbon atoms which may optionally contain one or more heteroatoms selected from oxygen, sulfur or nitrogen; n is an integer ranging from 1-4 and m is an integer 0 or 1.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ504104A NZ504104A (en) | 1998-01-23 | 1998-01-23 | Novel tricyclic compounds and their use in medicine, a process for their preparation, pharmaceutical compositions containing them, and their use in the manufacture of a medicament for treating diseases in which insulin is the underlying pathophysiological mechanism |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1998/001397 WO1999019313A1 (en) | 1997-10-27 | 1998-01-23 | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
NZ504104A NZ504104A (en) | 1998-01-23 | 1998-01-23 | Novel tricyclic compounds and their use in medicine, a process for their preparation, pharmaceutical compositions containing them, and their use in the manufacture of a medicament for treating diseases in which insulin is the underlying pathophysiological mechanism |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ504104A true NZ504104A (en) | 2003-03-28 |
Family
ID=19927850
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ504104A NZ504104A (en) | 1998-01-23 | 1998-01-23 | Novel tricyclic compounds and their use in medicine, a process for their preparation, pharmaceutical compositions containing them, and their use in the manufacture of a medicament for treating diseases in which insulin is the underlying pathophysiological mechanism |
Country Status (1)
Country | Link |
---|---|
NZ (1) | NZ504104A (en) |
-
1998
- 1998-01-23 NZ NZ504104A patent/NZ504104A/en unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ASS | Change of ownership |
Owner name: DR. REDDY S LABORATORIES LIMITED, IN Free format text: OLD OWNER(S): REDDY-CHEMINOR, INC.; DR. REDDY S RESEARCH FOUNDATION |
|
PSEA | Patent sealed | ||
RENW | Renewal (renewal fees accepted) | ||
RENW | Renewal (renewal fees accepted) |