NZ332926A - Immunogenic non-naturally occurring peptides and molecules based on somatostatin that modulate the activity of hormones or their receptors peptides, antibodies, vaccines and uses thereof - Google Patents

Immunogenic non-naturally occurring peptides and molecules based on somatostatin that modulate the activity of hormones or their receptors peptides, antibodies, vaccines and uses thereof

Info

Publication number
NZ332926A
NZ332926A NZ332926A NZ33292697A NZ332926A NZ 332926 A NZ332926 A NZ 332926A NZ 332926 A NZ332926 A NZ 332926A NZ 33292697 A NZ33292697 A NZ 33292697A NZ 332926 A NZ332926 A NZ 332926A
Authority
NZ
New Zealand
Prior art keywords
peptides
somatostatin
activity
receptors
hormones
Prior art date
Application number
NZ332926A
Inventor
Norman L Gerraty
Simon L Westbrook
David J Kingston
Original Assignee
Northstar Biolog Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Northstar Biolog Pty Ltd filed Critical Northstar Biolog Pty Ltd
Priority to NZ337256A priority Critical patent/NZ337256A/en
Publication of NZ332926A publication Critical patent/NZ332926A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4743—Insulin-like growth factor binding protein
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Emergency Medicine (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

This application relates to immunogenic, non-naturally occurring peptides and immunologically reactive molecules thereto which modulate the activity of hormones or the receptors therefor. These peptides are based on portions of somatostatin, somatostatin receptors and insulin-like growth factor binding protein. Methods of modulating hormonal activity in an animal and compositions therefor are also contemplated.
NZ332926A 1996-05-22 1997-05-22 Immunogenic non-naturally occurring peptides and molecules based on somatostatin that modulate the activity of hormones or their receptors peptides, antibodies, vaccines and uses thereof NZ332926A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ337256A NZ337256A (en) 1996-05-22 1997-05-22 Pharmaceutical carrier derived from deep sea shark oil and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPN9990A AUPN999096A0 (en) 1996-05-22 1996-05-22 Peptides, antibodies, vaccines & uses thereof
PCT/AU1997/000312 WO1997044352A1 (en) 1996-05-22 1997-05-22 Modulating the activity of hormones or their receptors - peptides, antibodies, vaccines and uses thereof

Publications (1)

Publication Number Publication Date
NZ332926A true NZ332926A (en) 2000-08-25

Family

ID=3794302

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ332926A NZ332926A (en) 1996-05-22 1997-05-22 Immunogenic non-naturally occurring peptides and molecules based on somatostatin that modulate the activity of hormones or their receptors peptides, antibodies, vaccines and uses thereof

Country Status (8)

Country Link
EP (1) EP1012171A1 (en)
JP (1) JP2000512130A (en)
CN (1) CN1226896A (en)
AU (1) AUPN999096A0 (en)
BR (1) BR9709038A (en)
CA (1) CA2255888A1 (en)
NZ (1) NZ332926A (en)
WO (1) WO1997044352A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002094124A2 (en) * 2001-05-18 2002-11-28 Arkion Life Sciences Method of increasing uniformity in avians
KR101086533B1 (en) 2002-05-24 2011-11-23 쉐링 코포레이션 Neutralizing human anti-IGFR antibody, a method for producing it and a composition comprising it
JP2007535895A (en) 2003-05-01 2007-12-13 イムクローン システムズ インコーポレイティド Fully human antibody against human insulin-like growth factor-1 receptor
ATE514783T1 (en) 2003-11-12 2011-07-15 Schering Corp PLASMID SYSTEM FOR EXPRESSING MULTIPLE GENES
PE20050928A1 (en) 2003-11-21 2005-11-08 Schering Corp THERAPEUTIC COMBINATIONS OF ANTI-IGFR1 ANTIBODY
FR2874156B1 (en) * 2004-08-13 2007-04-06 Univ Rennes 1 Etablissement Pu FEED SUPPLEMENT FOR ANIMALS AND METHOD OF CARRYING OUT SAID METHOD
MX2007006640A (en) 2004-12-03 2007-06-19 Schering Corp Biomarkers for pre-selection of patients for anti-igf1r therapy.
EP2100614B8 (en) 2005-06-17 2013-11-20 ImClone LLC Antibody against PDGFR-alpha for use in the treatment of tumours
ES2937113T3 (en) * 2006-01-20 2023-03-24 Starpharma Pty Ltd modified macromolecule
EA017265B1 (en) 2006-02-03 2012-11-30 Имклоун Элэлси Use of imc-a12 antibody being igf-ir inhibitor for treatment of prostate cancer
MX2010014078A (en) * 2008-06-25 2011-04-11 Braasch Biotech Llc Compositions and methods for enhanced somatostatin immunogenicity.
WO2014110601A1 (en) 2013-01-14 2014-07-17 Xencor, Inc. Novel heterodimeric proteins
US11053316B2 (en) 2013-01-14 2021-07-06 Xencor, Inc. Optimized antibody variable regions
US10858417B2 (en) 2013-03-15 2020-12-08 Xencor, Inc. Heterodimeric proteins
ME03666B (en) 2014-03-28 2020-10-20 Xencor Inc Bispecific antibodies that bind to cd38 and cd3
US10259887B2 (en) 2014-11-26 2019-04-16 Xencor, Inc. Heterodimeric antibodies that bind CD3 and tumor antigens
KR20170084326A (en) 2014-11-26 2017-07-19 젠코어 인코포레이티드 Heterodimeric antibodies that bind cd3 and tumor antigens
CN108699136B (en) 2015-12-07 2022-03-18 Xencor股份有限公司 Heterodimeric antibodies that bind CD3 and PSMA
EP4257613A3 (en) 2016-06-14 2023-12-13 Xencor, Inc. Bispecific checkpoint inhibitor antibodies
EP3475304B1 (en) * 2016-06-28 2022-03-23 Xencor, Inc. Heterodimeric antibodies that bind somatostatin receptor 2
WO2021231976A1 (en) 2020-05-14 2021-11-18 Xencor, Inc. Heterodimeric antibodies that bind prostate specific membrane antigen (psma) and cd3
KR102607909B1 (en) 2020-08-19 2023-12-01 젠코어 인코포레이티드 Anti-CD28 composition
IL305736A (en) 2021-03-09 2023-11-01 Xencor Inc Heterodimeric antibodies that bind cd3 and cldn6
EP4305065A1 (en) 2021-03-10 2024-01-17 Xencor, Inc. Heterodimeric antibodies that bind cd3 and gpc3

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH647246A5 (en) * 1981-03-06 1985-01-15 Sandoz Ag Polypeptide derivatives, their preparation and pharmaceutical products which contain these polypeptide derivatives
CH679045A5 (en) * 1987-06-29 1991-12-13 Sandoz Ag
US5187151A (en) * 1991-02-12 1993-02-16 Genentech, Inc. Use of binding protein with igf-i as an anabolic growth promoting agent
US5436155A (en) * 1991-12-31 1995-07-25 Arch Development Corporation Isolated DNA encoding a somatostatin receptor
JPH0782162A (en) * 1993-09-10 1995-03-28 Pola Chem Ind Inc Dermatic agent for external use

Also Published As

Publication number Publication date
JP2000512130A (en) 2000-09-19
CA2255888A1 (en) 1997-11-27
CN1226896A (en) 1999-08-25
WO1997044352A1 (en) 1997-11-27
EP1012171A1 (en) 2000-06-28
BR9709038A (en) 2000-01-04
AUPN999096A0 (en) 1996-06-13

Similar Documents

Publication Publication Date Title
NZ332926A (en) Immunogenic non-naturally occurring peptides and molecules based on somatostatin that modulate the activity of hormones or their receptors peptides, antibodies, vaccines and uses thereof
ATE410441T1 (en) COMPOSITIONS AND METHODS FOR TREATING INFECTIONS USING INDOLICIDINE ANALOGUES
AU1750297A (en) Humanized green fluorescent protein genes and methods
NZ227788A (en) Peptide having growth hormone regulatory effects, and compositions
GR3035227T3 (en) Neuroactive peptides
TR199900666T2 (en) Antibody to human parathormone-related peptides.
ATE296642T1 (en) REVERSE PHASE COMPOSITION FOR CONNECTIVE TISSUE REPAIR
NZ227787A (en) Peptides and compositions having growth hormone regulatory effects
HK1041790A1 (en) Protein material for slow digestion and its use
IL127874A0 (en) Truncated soluble tumor necrosis factor type-I and type-II receptors
WO1997046585A3 (en) Fragments of leptin (ob protein)
IL125267A0 (en) Compositions and methods for modulating cell proliferation using growth factor-polysaccharide binding fusion proteins
EP0783521B8 (en) Polypeptide compounds containing d-2-alkyltryptophan capable of promoting the release of growth hormone
WO1998017626A3 (en) Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides
WO2004089973A3 (en) Peptides, polypeptides, and proteins of reduced immunogenicity and methods for their production
EP0956032A4 (en) Proteins and compositions for modulating mitosis
AP9801399A0 (en) Zona pellucida proteins for contraception.
WO1991013984A3 (en) Interleukin-4 binding proteins
MX9710291A (en) Ligand inhibitors of insulin-like growth factor binding proteins and methods of use therefor.

Legal Events

Date Code Title Description
RENW Renewal (renewal fees accepted)