NZ332809A - Immunogenic complex comprising a oligo- or polysaccharide epitope and a carrier protein with a portion of an OmpA-type outer membrane protein of a bacterial and vaccines of such complexes containing same - Google Patents
Immunogenic complex comprising a oligo- or polysaccharide epitope and a carrier protein with a portion of an OmpA-type outer membrane protein of a bacterial and vaccines of such complexes containing sameInfo
- Publication number
- NZ332809A NZ332809A NZ332809A NZ33280997A NZ332809A NZ 332809 A NZ332809 A NZ 332809A NZ 332809 A NZ332809 A NZ 332809A NZ 33280997 A NZ33280997 A NZ 33280997A NZ 332809 A NZ332809 A NZ 332809A
- Authority
- NZ
- New Zealand
- Prior art keywords
- oligo
- ompa
- outer membrane
- vaccines
- bacterial
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0275—Salmonella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
The specification describes an immunogenic complex, characterised in that it contains at least one oligo- or polysaccharide epitope naturally present in bacteria, coupled with a carrier protein. The carrier protein comprises at least a fragment of an OmpA-type outer membrane protein of a gram-negative bacterium capable of enhancing the immunogenicity of the oligo-or polysaccharide epitope.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9605692A FR2748476B1 (en) | 1996-05-07 | 1996-05-07 | IMMUNOGENIC COMPLEX, ITS USE, ITS PREPARATION METHOD AND VACCINE CONTAINING THE SAME |
PCT/FR1997/000800 WO1997041888A1 (en) | 1996-05-07 | 1997-05-06 | Immunogenic complex, use, method of preparation thereof and vaccine containing same |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ332809A true NZ332809A (en) | 2000-05-26 |
Family
ID=9491907
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ332809A NZ332809A (en) | 1996-05-07 | 1997-05-06 | Immunogenic complex comprising a oligo- or polysaccharide epitope and a carrier protein with a portion of an OmpA-type outer membrane protein of a bacterial and vaccines of such complexes containing same |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0914152A1 (en) |
JP (1) | JP2000509707A (en) |
CN (1) | CN1221348A (en) |
AU (1) | AU733845B2 (en) |
BR (1) | BR9708979A (en) |
CA (1) | CA2254084A1 (en) |
FR (1) | FR2748476B1 (en) |
NZ (1) | NZ332809A (en) |
WO (1) | WO1997041888A1 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2776521B1 (en) * | 1998-03-27 | 2000-12-15 | Pf Medicament | USE OF P40 ACTIVE CONJUGATES BY NASAL |
FR2785542B1 (en) * | 1998-11-06 | 2001-02-09 | Pf Medicament | USE OF AN ENTEROMACTERY OmpA PROTEIN FOR THE SPECIFIC TARGETING OF A BIOLOGICALLY ACTIVE SUBSTANCE THAT IS ASSOCIATED WITH CELLS PRESENTING ANTIGENS SUCH AS HUMAN DENDRITIC CELLS |
US6146902A (en) * | 1998-12-29 | 2000-11-14 | Aventis Pasteur, Inc. | Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions |
FR2789588B1 (en) * | 1999-02-17 | 2001-05-04 | Pf Medicament | USE OF AN OMPA ENTEROBACTERIA PROTEIN ASSOCIATED WITH AN ANTIGEN IN A PHARMACEUTICAL COMPOSITION FOR GENERATING OR INCREASING ANTIVIRAL, PEST CONTROL OR ANTITUMOR CYTOTOXIC RESPONSE |
FR2789902A1 (en) * | 1999-02-24 | 2000-08-25 | Pf Medicament | Use of enterobacterial outer membrane protein as immunogenic carrier, particularly for contraceptive and anti-cancer vaccines, provides strong humoral response |
FR2790959B1 (en) * | 1999-03-15 | 2003-06-27 | Pf Medicament | USE OF BACTERIAL MEMBRANARY FRACTIONS WITH ADJUVANT EFFECT, THEIR PREPARATION METHODS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM |
FR2828106A1 (en) * | 2001-08-02 | 2003-02-07 | Pf Medicament | Composition containing peptide from low molecular weight outer membrane protein, useful for preparing vaccines against infections or cancer |
WO2007084856A2 (en) * | 2006-01-13 | 2007-07-26 | Baxter International Inc. | Method for purifying polysaccharides |
CN107184972B (en) * | 2017-06-20 | 2020-12-01 | 康希诺生物股份公司 | Mycobacterium tuberculosis OS-tb oligosaccharide conjugate and preparation method and application thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1331355C (en) * | 1986-04-21 | 1994-08-09 | Bioenterprises Pty. Ltd | Immunopotentation |
FR2682388B1 (en) * | 1991-10-10 | 1995-06-09 | Pasteur Merieux Serums Vacc | PROCESS FOR THE PREPARATION OF AN OLIGOSIDE BY DEPOLYMERIZATION OF A POLYOSIDE DERIVED FROM A PATHOGENIC AGENT, OLIGOSIDE THUS OBTAINED AND ITS USE IN PARTICULAR AS A VACCINE AGENT. |
US6153406A (en) * | 1993-07-23 | 2000-11-28 | North American Vaccine, Inc. | Method for the high level expression, purification and refolding of the outer membrane protein P2 from Haemophilus influenzae type B |
FR2718452B1 (en) * | 1994-04-06 | 1996-06-28 | Pf Medicament | Element of immunogen, immunogenic agent, pharmaceutical composition and method of preparation. |
FR2726471B1 (en) * | 1994-11-07 | 1997-01-31 | Pf Medicament | PROCESS FOR IMPROVING THE IMMUNOGENICITY OF AN IMMUNOGENIC COMPOUND OR A HAPTENA AND APPLICATION TO THE PREPARATION OF VACCINES |
FR2726472B1 (en) * | 1994-11-07 | 1997-01-31 | Pf Medicament | CARRIER WITH ADJUVANT EFFECT, IMMUNOGENIC COMPLEX CONTAINING THE SAME, PREPARATION METHOD THEREOF, NUCLEOTIDE SEQUENCE AND VACCINE |
-
1996
- 1996-05-07 FR FR9605692A patent/FR2748476B1/en not_active Expired - Fee Related
-
1997
- 1997-05-06 CA CA002254084A patent/CA2254084A1/en not_active Abandoned
- 1997-05-06 EP EP97923139A patent/EP0914152A1/en not_active Withdrawn
- 1997-05-06 NZ NZ332809A patent/NZ332809A/en unknown
- 1997-05-06 JP JP9539595A patent/JP2000509707A/en active Pending
- 1997-05-06 WO PCT/FR1997/000800 patent/WO1997041888A1/en not_active Application Discontinuation
- 1997-05-06 BR BR9708979A patent/BR9708979A/en not_active Application Discontinuation
- 1997-05-06 CN CN97195397A patent/CN1221348A/en active Pending
- 1997-05-06 AU AU29019/97A patent/AU733845B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
WO1997041888A1 (en) | 1997-11-13 |
JP2000509707A (en) | 2000-08-02 |
EP0914152A1 (en) | 1999-05-12 |
BR9708979A (en) | 1999-08-03 |
AU733845B2 (en) | 2001-05-31 |
CA2254084A1 (en) | 1997-11-13 |
CN1221348A (en) | 1999-06-30 |
FR2748476A1 (en) | 1997-11-14 |
FR2748476B1 (en) | 1998-08-14 |
AU2901997A (en) | 1997-11-26 |
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