NZ307592A - N-alkyl-n-glycosyl derivatives of alkyl esters of antifungal antibiotics of polyene macrolides - Google Patents

N-alkyl-n-glycosyl derivatives of alkyl esters of antifungal antibiotics of polyene macrolides

Info

Publication number
NZ307592A
NZ307592A NZ307592A NZ30759296A NZ307592A NZ 307592 A NZ307592 A NZ 307592A NZ 307592 A NZ307592 A NZ 307592A NZ 30759296 A NZ30759296 A NZ 30759296A NZ 307592 A NZ307592 A NZ 307592A
Authority
NZ
New Zealand
Prior art keywords
alkyl
antifungal antibiotics
polyene macrolides
glycosyl derivatives
alkyl esters
Prior art date
Application number
NZ307592A
Inventor
Edward Borowski
Jolanta Grzybowska
Pawel Sowinski
Jerzy Gumieniak
Andrzej Czerwinski
Original Assignee
British Tech Group
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Tech Group filed Critical British Tech Group
Publication of NZ307592A publication Critical patent/NZ307592A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ307592A 1995-05-13 1996-05-10 N-alkyl-n-glycosyl derivatives of alkyl esters of antifungal antibiotics of polyene macrolides NZ307592A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PL95308583A PL180253B1 (en) 1995-05-13 1995-05-13 N-methyl n-glycoside derivatives of methyl esters of antibiotic from the group of polyene macrolydes and their salts, method of obtaining them and using them in medical care
PCT/GB1996/001144 WO1996035701A1 (en) 1995-05-13 1996-05-10 Antibiotics

Publications (1)

Publication Number Publication Date
NZ307592A true NZ307592A (en) 1999-01-28

Family

ID=20065009

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ307592A NZ307592A (en) 1995-05-13 1996-05-10 N-alkyl-n-glycosyl derivatives of alkyl esters of antifungal antibiotics of polyene macrolides

Country Status (11)

Country Link
EP (1) EP0825995A1 (en)
JP (1) JPH11504647A (en)
KR (1) KR19990014843A (en)
AU (1) AU716883B2 (en)
CA (1) CA2220771A1 (en)
IL (1) IL118233A0 (en)
MX (1) MX9708637A (en)
NZ (1) NZ307592A (en)
PL (1) PL180253B1 (en)
WO (1) WO1996035701A1 (en)
ZA (1) ZA963787B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981721A (en) * 1997-10-23 1999-11-09 Karykion Corporation Polyene macrolide schiff bases, their alkyl esters and processes for preparing polyene macrolide alkyl ester salts thereof
EP1278527A4 (en) 2000-01-14 2003-04-09 Intrabiotics Pharmaceuticals Derivatives of polyene macrolides and preparation and use thereof
KR100687748B1 (en) * 2005-06-23 2007-02-27 한국전자통신연구원 Method and System for Fast Handover being independent of Mobile Node
GB0712881D0 (en) 2007-07-03 2007-08-15 Biosergen As Compounds
US9447136B2 (en) 2012-03-09 2016-09-20 Blirt S.A. Semisynthetic derivatives of Nystatin A1
JP2015519389A (en) * 2012-06-15 2015-07-09 ブリート スポルカ アクシヤ N-substituted second generation derivatives of the antifungal antibiotic amphotericin B and methods for their preparation and application
SG11201610162XA (en) 2014-06-12 2017-01-27 Shionogi & Co Polyene macrolide derivative
WO2016168568A1 (en) * 2015-04-15 2016-10-20 Revolution Medicines, Inc. Derivatives of amphotericin b
CN112920238B (en) * 2021-01-27 2022-09-30 河南农业大学 Sugar amine Amadori derivative and preparation method and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI60877C (en) * 1971-08-13 1982-04-13 Politechnika Gdanska PROTECTION OF THERAPEUTIC ACTIVITIES OF THERAPEUTIC ACTIVITIES WITH A DISPENSABLE POLYENMACROLIDANTIBIOTICS-N-GLYCOSYL DERIVATIVES
US4002741A (en) * 1974-04-24 1977-01-11 Valter Osvaldovich Kulbakh Meglumine complex fungicidal polyene macrolide antibiotic compositions and treatment method
US4195172A (en) * 1976-04-22 1980-03-25 Politechnika Gdanska Salts of N-glycosyl derivatives of polyene macrolides, especially N-methylglucamine salts as well as the method of their preparation
US4144328A (en) * 1977-02-28 1979-03-13 Vainshtein Viktor A N,N,N-Trimethyl derivatives of polyene amphoteric antibiotics, process of producing same and pharmaceutical composition
FR2654339B1 (en) * 1989-11-14 1994-10-28 Mayoly Spindler Laboratoires NOVEL SOLUBLE AND NON-TOXIC DERIVATIVES OF BASIC POLYENIC MACROLIDES, THEIR PREPARATION AND THEIR APPLICATIONS.

Also Published As

Publication number Publication date
PL308583A1 (en) 1996-11-25
IL118233A0 (en) 1996-09-12
EP0825995A1 (en) 1998-03-04
CA2220771A1 (en) 1996-11-14
AU716883B2 (en) 2000-03-09
KR19990014843A (en) 1999-02-25
ZA963787B (en) 1997-11-13
PL180253B1 (en) 2001-01-31
AU5698396A (en) 1996-11-29
WO1996035701A1 (en) 1996-11-14
MX9708637A (en) 1998-02-28
JPH11504647A (en) 1999-04-27

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