NZ272476A - Pharmaceutical composition comprising methotrexate, use in attenuating lung capillary leak - Google Patents

Pharmaceutical composition comprising methotrexate, use in attenuating lung capillary leak

Info

Publication number
NZ272476A
NZ272476A NZ272476A NZ27247695A NZ272476A NZ 272476 A NZ272476 A NZ 272476A NZ 272476 A NZ272476 A NZ 272476A NZ 27247695 A NZ27247695 A NZ 27247695A NZ 272476 A NZ272476 A NZ 272476A
Authority
NZ
New Zealand
Prior art keywords
methotrexate
administration
interleukin
administered
capillary leak
Prior art date
Application number
NZ272476A
Other languages
English (en)
Inventor
Shirvasu Kerwar Suresh
Marcel Wick Michael
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of NZ272476A publication Critical patent/NZ272476A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NZ272476A 1994-07-01 1995-06-30 Pharmaceutical composition comprising methotrexate, use in attenuating lung capillary leak NZ272476A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/269,702 US5593671A (en) 1994-07-01 1994-07-01 Method of attenuating lung capillary leak in a mammal

Publications (1)

Publication Number Publication Date
NZ272476A true NZ272476A (en) 1997-06-24

Family

ID=23028336

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ272476A NZ272476A (en) 1994-07-01 1995-06-30 Pharmaceutical composition comprising methotrexate, use in attenuating lung capillary leak

Country Status (9)

Country Link
US (1) US5593671A (cg-RX-API-DMAC10.html)
EP (1) EP0692251A1 (cg-RX-API-DMAC10.html)
JP (1) JPH0826998A (cg-RX-API-DMAC10.html)
KR (1) KR960003728A (cg-RX-API-DMAC10.html)
AU (1) AU2335195A (cg-RX-API-DMAC10.html)
CA (1) CA2152981A1 (cg-RX-API-DMAC10.html)
HU (1) HUT74245A (cg-RX-API-DMAC10.html)
NZ (1) NZ272476A (cg-RX-API-DMAC10.html)
TW (1) TW294596B (cg-RX-API-DMAC10.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200100590T2 (tr) 1998-08-28 2001-07-23 Biomedicines, Inc. Olumsuz interleukin-2 etkilerinin hafifletilmesi metodu
US6544504B1 (en) 1999-07-28 2003-04-08 Schering Corporation Combined use of interleukin 10 and methotrexate for immuno-modulatory therapy
MXPA03001247A (es) * 2000-08-10 2003-10-15 Uab Research Foundation Composiciones que contienen inhibidor de dihidrofolato reductasa y folato.
KR20070003934A (ko) * 2004-03-05 2007-01-05 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 치료제의 환자 내약성을 예측하기 위한 시험관 내 테스트시스템
DE102006033837A1 (de) 2006-07-21 2008-01-31 Medac Gesellschaft für klinische Spezialpräparate m.b.H Konzentrierte Methotrexat-Lösungen
GB201419261D0 (en) 2014-10-29 2014-12-10 Therakind Ltd Formulations

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK86988A (da) * 1987-02-25 1988-08-26 Takeda Chemical Industries Ltd Liposompraeparat og anvendelse deraf

Also Published As

Publication number Publication date
TW294596B (cg-RX-API-DMAC10.html) 1997-01-01
KR960003728A (ko) 1996-02-23
US5593671A (en) 1997-01-14
EP0692251A1 (en) 1996-01-17
HU9501980D0 (en) 1995-08-28
JPH0826998A (ja) 1996-01-30
AU2335195A (en) 1996-01-18
CA2152981A1 (en) 1996-01-02
HUT74245A (en) 1996-11-28

Similar Documents

Publication Publication Date Title
EP0911033B2 (en) Use of consensus interferon for reducing the side effects of interferon treatment in viral hepatitis.
Baldwin et al. Granulocyte-macrophage colony-stimulating factor enhances neutrophil function in acquired immunodeficiency syndrome patients.
US5534545A (en) Parenteral amino acid formulations for the inhibition of systemic hypotension associated with nitric oxide production
EP0493468B1 (en) Anti-tumor preparation comprising interleukin-2 and histamine, analogs thereof or h2-receptor agonists
CA1297005C (en) Pharmaceutical agent for the treatment of myelogenous leukemia
EP0344880A2 (en) Pharmaceutical compositions with anti-cancer activity
EP0553294B1 (en) The manufacture of compositions for the treatment of cell proliferation disorders
US5593671A (en) Method of attenuating lung capillary leak in a mammal
EP0663826B1 (en) Amino acids containing parenteral formulations for the treatment of hypotension and related pathologies
Atkinson et al. GM‐CSF after allogeneic bone marrow transplantation: accelerated recovery of neutrophils, monocytes and lymphocytes
US6267968B1 (en) MDP derivatives and conjugates having haematipoietic function stimulating activity, and compositions containing same
US5026544A (en) Methods and compositions for inhibiting the growth of neoplastic cells
JP3459268B2 (ja) 抗癌剤
EP0369079B1 (en) Pharmaceutical compositions with anti-cancer activity and method for the treatment of cancer
Kitayama et al. Granulocyte colony-stimulating factor in allogeneic bone marrow transplantation
EP0394542A1 (en) Bone marrow cell recovery with synthetic csf inducers
JPH05271095A (ja) 抗癌剤
AU2024353689A1 (en) Therapeutic agent for rheumatoid arthritis
US5264418A (en) Hemolymphopoietic growth factors, process for purifying and producing hemolymphopoietic growth factors and pharmaceutical compositions made therefrom
JPH06504767A (ja) B−細胞悪性疾患の治療のための薬剤組成物
Clutterbuck et al. The response of human myeloid leukaemia xenografts to human recombinant tumour necrosis factor
HK1010340B (en) The manufacture of compositions for the treatment of cell proliferation disorders
Yee Colony-stimulating factors and tomorrow's pharmacy: Why we must be ready
HK1018595B (en) Use of consensus interferon for reducing the side effects of interferon treatment in viral hepatitis
JPH08169842A (ja) 白血球増多促進剤