NZ248627A - Pharmaceutical adsorbate composition: pyridine derivative as the active agent together with silica, an inert auxiliary and optionally starch - Google Patents

Pharmaceutical adsorbate composition: pyridine derivative as the active agent together with silica, an inert auxiliary and optionally starch

Info

Publication number
NZ248627A
NZ248627A NZ248627A NZ24862793A NZ248627A NZ 248627 A NZ248627 A NZ 248627A NZ 248627 A NZ248627 A NZ 248627A NZ 24862793 A NZ24862793 A NZ 24862793A NZ 248627 A NZ248627 A NZ 248627A
Authority
NZ
New Zealand
Prior art keywords
pharmaceutical
silica
active agent
pyridine derivative
agent together
Prior art date
Application number
NZ248627A
Other languages
English (en)
Inventor
Theophil Hornykiewytsch
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NZ248627A publication Critical patent/NZ248627A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
NZ248627A 1992-09-11 1993-09-09 Pharmaceutical adsorbate composition: pyridine derivative as the active agent together with silica, an inert auxiliary and optionally starch NZ248627A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4230371 1992-09-11

Publications (1)

Publication Number Publication Date
NZ248627A true NZ248627A (en) 1995-01-27

Family

ID=6467712

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ248627A NZ248627A (en) 1992-09-11 1993-09-09 Pharmaceutical adsorbate composition: pyridine derivative as the active agent together with silica, an inert auxiliary and optionally starch

Country Status (13)

Country Link
EP (1) EP0587137A1 (enrdf_load_stackoverflow)
JP (1) JPH06192093A (enrdf_load_stackoverflow)
KR (1) KR940006583A (enrdf_load_stackoverflow)
AU (1) AU663000B2 (enrdf_load_stackoverflow)
CA (1) CA2105913A1 (enrdf_load_stackoverflow)
FI (1) FI933954A7 (enrdf_load_stackoverflow)
HU (1) HUT67577A (enrdf_load_stackoverflow)
IL (1) IL106953A0 (enrdf_load_stackoverflow)
MX (1) MX9305578A (enrdf_load_stackoverflow)
NO (1) NO933237L (enrdf_load_stackoverflow)
NZ (1) NZ248627A (enrdf_load_stackoverflow)
TW (1) TW222585B (enrdf_load_stackoverflow)
ZA (1) ZA936695B (enrdf_load_stackoverflow)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2160368A1 (en) * 1993-06-04 1994-12-22 Stanley J. Lech Preparations containing silicon dioxide to improve the taste thereof
US5626878A (en) * 1995-01-10 1997-05-06 Warner Lambert Company Reduction of electrostatic forces between magnesium trisilicate adsorbates
ATE254907T1 (de) * 1998-12-18 2003-12-15 Abbott Lab Natriumhydrogendivalproat-formulierungen mit gesteuerter freigabe
CN101001613B (zh) * 2004-06-28 2010-09-29 生命周期药物公司 作为液体制剂载体的多孔片剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2879161A (en) * 1956-05-14 1959-03-24 American Cyanamid Co Stable dry powder compositions containing choline chloride and methods of preparing same
DE3409063A1 (de) * 1984-03-13 1985-09-19 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von fliessfaehigen cholinchlorid-kieselsaeure-pulvern
DE3924093A1 (de) * 1989-07-20 1991-02-07 Hoechst Ag N,n'-bis(alkoxy-alkyl)-pyridin-2,4-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
DE4020570A1 (de) * 1990-06-28 1992-01-02 Hoechst Ag 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung
GB9025251D0 (en) * 1990-11-20 1991-01-02 Solomon Montague C Nifedipine dosage forms

Also Published As

Publication number Publication date
NO933237D0 (no) 1993-09-10
FI933954A0 (fi) 1993-09-09
CA2105913A1 (en) 1994-03-12
HUT67577A (en) 1995-04-28
JPH06192093A (ja) 1994-07-12
FI933954L (fi) 1994-03-12
EP0587137A1 (de) 1994-03-16
AU4626293A (en) 1994-03-17
IL106953A0 (en) 1993-12-28
MX9305578A (es) 1994-03-31
NO933237L (no) 1994-03-14
FI933954A7 (fi) 1994-03-12
HU9302555D0 (en) 1993-11-29
KR940006583A (ko) 1994-04-25
TW222585B (enrdf_load_stackoverflow) 1994-04-21
ZA936695B (en) 1994-04-05
AU663000B2 (en) 1995-09-21

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