NZ241538A - Electrochemiluminescent assay using magnetically responsive suspended particles, and apparatus - Google Patents
Electrochemiluminescent assay using magnetically responsive suspended particles, and apparatusInfo
- Publication number
- NZ241538A NZ241538A NZ24153892A NZ24153892A NZ241538A NZ 241538 A NZ241538 A NZ 241538A NZ 24153892 A NZ24153892 A NZ 24153892A NZ 24153892 A NZ24153892 A NZ 24153892A NZ 241538 A NZ241538 A NZ 241538A
- Authority
- NZ
- New Zealand
- Prior art keywords
- suspended particles
- magnetically responsive
- electrochemiluminescent assay
- responsive suspended
- electrochemiluminescent
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/30—Electrochemically active labels
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plasma & Fusion (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65242791A | 1991-02-06 | 1991-02-06 | |
US82726992A | 1992-02-03 | 1992-02-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ241538A true NZ241538A (en) | 1993-02-25 |
Family
ID=27096296
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ24153892A NZ241538A (en) | 1991-02-06 | 1992-02-05 | Electrochemiluminescent assay using magnetically responsive suspended particles, and apparatus |
Country Status (7)
Country | Link |
---|---|
JP (2) | JP3013937B2 (en) |
CN (1) | CN1107863C (en) |
AU (1) | AU1530492A (en) |
IE (1) | IE69371B1 (en) |
IL (1) | IL100866A (en) |
NZ (1) | NZ241538A (en) |
WO (1) | WO1992014138A1 (en) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5466416A (en) * | 1993-05-14 | 1995-11-14 | Ghaed; Ali | Apparatus and methods for carrying out electrochemiluminescence test measurements |
JPH07271865A (en) | 1994-04-01 | 1995-10-20 | Mitsubishi Corp | Method for managing copyright of data base |
US7036019B1 (en) | 1994-04-01 | 2006-04-25 | Intarsia Software Llc | Method for controlling database copyrights |
US6744894B1 (en) | 1994-04-01 | 2004-06-01 | Mitsubishi Corporation | Data management system |
EP1691315A1 (en) | 1994-10-27 | 2006-08-16 | Intarsia Software LLC | Data copyright management system |
US6424715B1 (en) | 1994-10-27 | 2002-07-23 | Mitsubishi Corporation | Digital content management system and apparatus |
DE69532434T2 (en) | 1994-10-27 | 2004-11-11 | Mitsubishi Corp. | Device for file copyright management system |
US5744367A (en) * | 1994-11-10 | 1998-04-28 | Igen International, Inc. | Magnetic particle based electrochemiluminescent detection apparatus and method |
US5538687A (en) * | 1994-12-16 | 1996-07-23 | Behringer Mannheim Gmbh | Apparatus for generating optically detectable signals by applying electrical potentials to sample liquids |
US6319670B1 (en) * | 1995-05-09 | 2001-11-20 | Meso Scale Technology Llp | Methods and apparatus for improved luminescence assays using microparticles |
AU5920696A (en) * | 1995-05-18 | 1996-11-29 | Igen, Inc. | Method for derivitizing electrodes and assay methods using s uch derivitized electrodes |
US8595502B2 (en) | 1995-09-29 | 2013-11-26 | Intarsia Software Llc | Data management system |
US7801817B2 (en) | 1995-10-27 | 2010-09-21 | Makoto Saito | Digital content management system and apparatus |
EP0859230A1 (en) * | 1997-02-10 | 1998-08-19 | Cranfield University | Detection of analytes using electrochemistry |
EP0859229A1 (en) * | 1997-02-10 | 1998-08-19 | Gist-Brocades B.V. | Detection of analytes using electrochemistry |
US6100045A (en) * | 1997-02-10 | 2000-08-08 | Dsm N.V. | Detection of analytes using electrochemistry |
US6146838A (en) * | 1997-03-18 | 2000-11-14 | Igen International, Inc. | Detecting water-borne parasites using electrochemiluminescence |
DE19803528A1 (en) * | 1998-01-30 | 1999-08-05 | Roche Diagnostics Gmbh | Method for analyzing a sample using an electrochemiluminescence binding reaction test |
GB9815042D0 (en) | 1998-07-10 | 1998-09-09 | Imperial College | Detector |
JP4763866B2 (en) | 1998-10-15 | 2011-08-31 | インターシア ソフトウェア エルエルシー | Method and apparatus for protecting digital data by double re-encryption |
JP2003504642A (en) * | 1999-07-16 | 2003-02-04 | ダブリューエム・マーシュ・ライス・ユニバーシティー | Metallic fine shell for biosensing applications |
US6136268A (en) * | 1999-08-17 | 2000-10-24 | Orion Diagnostica | Method for luminescence measurements |
AU2002211363A1 (en) * | 2000-10-10 | 2002-04-22 | Aviva Biosciences Corporation | Individually addressable micro-electromagnetic unit array chips in horizontal configurations |
US6518747B2 (en) * | 2001-02-16 | 2003-02-11 | Quantum Design, Inc. | Method and apparatus for quantitative determination of accumulations of magnetic particles |
US7497827B2 (en) | 2004-07-13 | 2009-03-03 | Dexcom, Inc. | Transcutaneous analyte sensor |
US10022078B2 (en) | 2004-07-13 | 2018-07-17 | Dexcom, Inc. | Analyte sensor |
JP2006514264A (en) * | 2002-05-08 | 2006-04-27 | イサム リサーチ デベロップメント カンパニー オブ ザ ヘブルー ユニバーシティ オブ エルサレム | Measurement of specimens in liquid solvents |
CN100538362C (en) * | 2002-11-07 | 2009-09-09 | 株式会社三菱化学药得论 | Be used to collect the magnetic material and the application thereof of magnetic-particle |
US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
AT413153B (en) * | 2004-03-11 | 2005-11-15 | Christian Doppler Labor Fuer S | METHOD AND DEVICE FOR DETECTING MARKED MICROPARTICLES |
BRPI0708677A2 (en) | 2006-03-09 | 2011-06-21 | Hoffmann La Roche | anti-drug antibody assay |
GB2436616A (en) * | 2006-03-29 | 2007-10-03 | Inverness Medical Switzerland | Assay device and method |
ES2428876T3 (en) | 2006-09-12 | 2013-11-12 | F. Hoffmann-La Roche Ag | Antipharmaceutical Antibody Assay |
CA2856143C (en) * | 2007-02-09 | 2016-11-01 | Advanced Liquid Logic, Inc. | Droplet actuator devices and methods employing magnetic beads |
CN101617228A (en) | 2007-02-27 | 2009-12-30 | 霍夫曼-拉罗奇有限公司 | Be used to assess method at the inhibition activity of the antibody of insulin-like growth factor I receptor |
GB0812679D0 (en) * | 2008-07-10 | 2008-08-20 | Sec Dep For Innovation Universities | Sample carrier for effecting chemical assays |
WO2009077127A1 (en) | 2007-12-15 | 2009-06-25 | F. Hoffmann-La Roche Ag | Distinguishing assay |
US8614297B2 (en) | 2008-12-22 | 2013-12-24 | Hoffmann-La Roche Inc. | Anti-idiotype antibody against an antibody against the amyloid β peptide |
WO2012022774A1 (en) | 2010-08-19 | 2012-02-23 | Roche Diagnostics Gmbh | An assay for measurement of antibodies binding to a therapeutic monoclonal antibody |
JP5481326B2 (en) * | 2010-09-08 | 2014-04-23 | 株式会社日立製作所 | Measuring apparatus and measuring method using biomaterial detection element |
WO2012143380A1 (en) | 2011-04-20 | 2012-10-26 | F. Hoffmann-La Roche Ag | Microwaves for immunohistochemical analysis |
US20130011394A1 (en) | 2011-06-22 | 2013-01-10 | Hoffmann-La Roche Inc. | Complexes comprising mhc class i fusion polypeptides and antigen-specific antibodies and methods of use |
BR112014011535A2 (en) | 2011-12-19 | 2017-05-09 | Hoffmann La Roche | method for in vitro and immunological determination of the presence and / or amount of a binding partner, in vitro method and use of an antibody |
WO2013113663A1 (en) | 2012-02-01 | 2013-08-08 | F. Hoffmann-La Roche Ag | Method for the detection of a binding partner of a multispecific binder |
EP2634579B1 (en) * | 2012-03-03 | 2014-12-17 | Astrium GmbH | Method for performing immuno-assays in zero gravity |
KR102084805B1 (en) | 2012-03-08 | 2020-03-04 | 에프. 호프만-라 로슈 아게 | Multiplexed chromatography-immunoassay method for the characterization of circulating immune complexes |
US9964539B2 (en) | 2012-07-06 | 2018-05-08 | Hitachi High-Technologies Corporation | Analysis device and analysis method |
WO2014009474A1 (en) | 2012-07-13 | 2014-01-16 | F. Hoffmann-La Roche Ag | Method for the detection of a multispecific binder |
PL2935328T3 (en) | 2012-12-21 | 2019-02-28 | Hoffmann La Roche | Disulfide-linked multivalent mhc class i comprising multi-function proteins |
RU2674996C2 (en) | 2013-07-04 | 2018-12-14 | Ф. Хоффманн-Ля Рош Аг | Immunoassay method with interference suppression for determination of antibodies for drugs in serum samples |
CN103954664A (en) * | 2014-04-10 | 2014-07-30 | 深圳普门科技有限公司 | Electrode disk, preparation method thereof and electrochemical flow cell based on same |
MX2018005036A (en) | 2015-10-29 | 2018-08-01 | Hoffmann La Roche | Anti-variant fc-region antibodies and methods of use. |
JP6807944B2 (en) | 2015-11-30 | 2021-01-06 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | Immunoassay method for measuring Fc region-modified antibody |
JP7168230B2 (en) * | 2017-06-06 | 2022-11-09 | ノースウエスタン ユニバーシティ | Trans-interfacial magnetic separation |
MX2020004921A (en) | 2017-11-29 | 2020-08-27 | Hoffmann La Roche | Target interference suppressed anti-drug antibody assay. |
CN113272327A (en) | 2018-12-30 | 2021-08-17 | 豪夫迈·罗氏有限公司 | Anti-rabbit CD19 antibodies and methods of use thereof |
EP3969907A1 (en) | 2019-05-13 | 2022-03-23 | F. Hoffmann-La Roche AG | Interference-suppressed pharmacokinetic immunoassay |
EP4085251B1 (en) | 2020-01-02 | 2024-07-31 | F. Hoffmann-La Roche AG | Method for determining the amount of a therapeutic antibody in the brain |
IL298923A (en) | 2020-06-16 | 2023-02-01 | Hoffmann La Roche | Method for determining the free antigen of an antibody in a sample |
EP4320444A1 (en) | 2021-04-09 | 2024-02-14 | F. Hoffmann-La Roche AG | Process for selecting cell clones expressing a heterologous polypeptide |
EP4388014A1 (en) | 2021-08-19 | 2024-06-26 | F. Hoffmann-La Roche AG | Multivalent anti-variant fc-region antibodies and methods of use |
EP4416301A1 (en) | 2021-12-21 | 2024-08-21 | F. Hoffmann-La Roche AG | Method for the determination of hydrolytic activity |
WO2024044622A1 (en) | 2022-08-24 | 2024-02-29 | Amgen Inc. | Anti-drug antibody assays |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0030087A1 (en) * | 1979-11-13 | 1981-06-10 | Technicon Instruments Company Limited | Immunoassay method and apparatus and kit for carrying out the method |
DE3013765A1 (en) * | 1980-04-10 | 1981-10-15 | Philips Patentverwaltung Gmbh, 2000 Hamburg | DETECTOR ARRANGEMENT, ESPECIALLY FOR LIQUID CHROMATOGRAPHY |
US4652533A (en) * | 1983-04-28 | 1987-03-24 | Pandex Laboratories, Inc. | Method of solid phase immunoassay incorporating a luminescent label |
US4628037A (en) * | 1983-05-12 | 1986-12-09 | Advanced Magnetics, Inc. | Binding assays employing magnetic particles |
US5238808A (en) * | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
GB8507706D0 (en) * | 1985-03-25 | 1985-05-01 | Genetics Int Inc | Magnetic nucleic acid sequences |
CA1339465C (en) * | 1986-04-30 | 1997-09-16 | Richard J. Massey | Electrochemiluminescent assays |
US5093268A (en) * | 1988-04-28 | 1992-03-03 | Igen, Inc. | Apparatus for conducting a plurality of simultaneous measurements of electrochemiluminescent phenomena |
US5061445A (en) * | 1988-11-03 | 1991-10-29 | Igen, Inc. | Apparatus for conducting measurements of electrochemiluminescent phenomena |
US5068088A (en) * | 1988-11-03 | 1991-11-26 | Igen, Inc. | Method and apparatus for conducting electrochemiluminescent measurements |
-
1992
- 1992-02-04 IL IL10086692A patent/IL100866A/en not_active IP Right Cessation
- 1992-02-05 JP JP4507261A patent/JP3013937B2/en not_active Expired - Lifetime
- 1992-02-05 IE IE920381A patent/IE69371B1/en not_active IP Right Cessation
- 1992-02-05 WO PCT/US1992/000982 patent/WO1992014138A1/en active Application Filing
- 1992-02-05 NZ NZ24153892A patent/NZ241538A/en not_active IP Right Cessation
- 1992-02-05 AU AU15304/92A patent/AU1530492A/en not_active Abandoned
- 1992-02-07 CN CN 92101900 patent/CN1107863C/en not_active Expired - Lifetime
-
1998
- 1998-07-15 JP JP10233430A patent/JP3128541B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU1530492A (en) | 1992-09-07 |
IE920381A1 (en) | 1992-08-12 |
WO1992014138A1 (en) | 1992-08-20 |
JPH11125601A (en) | 1999-05-11 |
CN1065339A (en) | 1992-10-14 |
IL100866A (en) | 1995-10-31 |
JP3128541B2 (en) | 2001-01-29 |
JPH06508203A (en) | 1994-09-14 |
CN1107863C (en) | 2003-05-07 |
IE69371B1 (en) | 1996-09-04 |
JP3013937B2 (en) | 2000-02-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RENW | Renewal (renewal fees accepted) | ||
ASS | Change of ownership |
Owner name: BIOVERIS CORPORATION, US Free format text: OLD OWNER(S): IGEN INTERNATIONAL, INC.; EISAI COMPANY LTD Owner name: EISAI COMPANY LTD, JP Free format text: OLD OWNER(S): IGEN INTERNATIONAL, INC.; EISAI COMPANY LTD |
|
RENW | Renewal (renewal fees accepted) | ||
EXPY | Patent expired |