NZ232389A - Thio ether derivatives of aminoalkoxyphenyl compounds and pharmaceutical compositions - Google Patents

Thio ether derivatives of aminoalkoxyphenyl compounds and pharmaceutical compositions

Info

Publication number
NZ232389A
NZ232389A NZ232389A NZ23238990A NZ232389A NZ 232389 A NZ232389 A NZ 232389A NZ 232389 A NZ232389 A NZ 232389A NZ 23238990 A NZ23238990 A NZ 23238990A NZ 232389 A NZ232389 A NZ 232389A
Authority
NZ
New Zealand
Prior art keywords
aminoalkoxyphenyl
image
group
compounds
radical
Prior art date
Application number
NZ232389A
Inventor
Jean Gubin
Pierre Chatelain
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of NZ232389A publication Critical patent/NZ232389A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

The invention relates to aminoalkoxyphenyl derivatives which are active, in particular, in the treatment of pathological syndromes of the cardiovascular system, corresponding to the general formula: <IMAGE> as well as their pharmaceutically acceptable salts, in which formula: B represents an -S-, -SO- or -SO2- group, R1 and R2, which are identical or different, each represent hydrogen, a methyl or ethyl radical or a halogen such as chlorine, bromine or iodine, A represents a linear or branched alkylene radical having from 2 to 5 carbon atoms or a 2-hydroxypropylene radical in which the hydroxyl is optionally substituted with a lower alkyl radical, Am represents a group: <IMAGE> and Cy represents a group of formula: <IMAGE>
NZ232389A 1989-02-06 1990-02-05 Thio ether derivatives of aminoalkoxyphenyl compounds and pharmaceutical compositions NZ232389A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30650089A 1989-02-06 1989-02-06

Publications (1)

Publication Number Publication Date
NZ232389A true NZ232389A (en) 1991-08-27

Family

ID=23185581

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ232389A NZ232389A (en) 1989-02-06 1990-02-05 Thio ether derivatives of aminoalkoxyphenyl compounds and pharmaceutical compositions

Country Status (9)

Country Link
EP (1) EP0382618B1 (en)
JP (1) JPH02250862A (en)
AT (1) ATE128137T1 (en)
AU (1) AU638692B2 (en)
CA (1) CA2008985A1 (en)
DE (1) DE69022442T2 (en)
NZ (1) NZ232389A (en)
PT (1) PT93044A (en)
ZA (1) ZA90865B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2642755B1 (en) * 1989-02-07 1993-11-05 Sanofi
FR2642756B1 (en) * 1989-02-07 1994-03-04 Sanofi CYCLOAMINOALKOXYPHENYL DERIVATIVES, THEIR PREPARATION METHOD AND THE PHARMACEUTICAL OR VETERINARY COMPOSITIONS CONTAINING THE SAME
FR2692578B1 (en) * 1992-06-23 1995-06-30 Sanofi Elf INDOLIZIN DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF FOR THE PREPARATION OF AMINOALKOXYBENZENESULFONYL-INDOLIZINE COMPOUNDS WITH PHARMACEUTICAL ACTIVITY.
FR2692574B1 (en) * 1992-06-23 1995-06-23 Sanofi Elf 4-HYDROXY BENZENETHIO DERIVATIVES, THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF AMINOALKOXYBENZENESULFONYL DERIVATIVES.
FR2708604B1 (en) * 1993-07-30 1995-10-20 Sanofi Elf Use of benzenesulfonyl-indole derivatives for the preparation of medicaments.
DE4422517A1 (en) * 1994-06-28 1996-01-04 Dresden Arzneimittel New (2- (3,4-dimethoxy-phenyl) -ethyl) - (2-phenoxy-ethyl) -amines, processes for their preparation and their use as medicines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117128A (en) * 1976-08-03 1978-09-26 Smithkline Corporation Sulfonyl benzofurans and benzothiophenes having coronary vasodilator activity
FR2594438B1 (en) * 1986-02-14 1990-01-26 Labaz Sanofi Nv INDOLIZINE DERIVATIVES, THEIR PREPARATION PROCESS AND THE COMPOSITIONS CONTAINING SAME
IL87181A (en) * 1987-08-07 1993-08-18 Sanofi Sa Aminoalkoxyphenyl derivatives, their preparation and pharmaceutical and veterinary compositions containing them
FR2642755B1 (en) * 1989-02-07 1993-11-05 Sanofi

Also Published As

Publication number Publication date
AU638692B2 (en) 1993-07-08
PT93044A (en) 1990-08-31
AU4909590A (en) 1990-08-09
JPH02250862A (en) 1990-10-08
DE69022442D1 (en) 1995-10-26
EP0382618A3 (en) 1991-11-13
EP0382618B1 (en) 1995-09-20
ATE128137T1 (en) 1995-10-15
EP0382618A2 (en) 1990-08-16
ZA90865B (en) 1991-10-30
DE69022442T2 (en) 1996-05-09
CA2008985A1 (en) 1990-08-06

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