AU4909590A - Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same - Google Patents

Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same

Info

Publication number
AU4909590A
AU4909590A AU49095/90A AU4909590A AU4909590A AU 4909590 A AU4909590 A AU 4909590A AU 49095/90 A AU49095/90 A AU 49095/90A AU 4909590 A AU4909590 A AU 4909590A AU 4909590 A AU4909590 A AU 4909590A
Authority
AU
Australia
Prior art keywords
image
group
radical
formula
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU49095/90A
Other versions
AU638692B2 (en
Inventor
Pierre Chatelain
Jean Gubin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of AU4909590A publication Critical patent/AU4909590A/en
Application granted granted Critical
Publication of AU638692B2 publication Critical patent/AU638692B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

The invention relates to aminoalkoxyphenyl derivatives which are active, in particular, in the treatment of pathological syndromes of the cardiovascular system, corresponding to the general formula: <IMAGE> as well as their pharmaceutically acceptable salts, in which formula: B represents an -S-, -SO- or -SO2- group, R1 and R2, which are identical or different, each represent hydrogen, a methyl or ethyl radical or a halogen such as chlorine, bromine or iodine, A represents a linear or branched alkylene radical having from 2 to 5 carbon atoms or a 2-hydroxypropylene radical in which the hydroxyl is optionally substituted with a lower alkyl radical, Am represents a group: <IMAGE> and Cy represents a group of formula: <IMAGE>
AU49095/90A 1989-02-06 1990-02-05 Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same Ceased AU638692B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30650089A 1989-02-06 1989-02-06
US306500 1989-02-06

Publications (2)

Publication Number Publication Date
AU4909590A true AU4909590A (en) 1990-08-09
AU638692B2 AU638692B2 (en) 1993-07-08

Family

ID=23185581

Family Applications (1)

Application Number Title Priority Date Filing Date
AU49095/90A Ceased AU638692B2 (en) 1989-02-06 1990-02-05 Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same

Country Status (9)

Country Link
EP (1) EP0382618B1 (en)
JP (1) JPH02250862A (en)
AT (1) ATE128137T1 (en)
AU (1) AU638692B2 (en)
CA (1) CA2008985A1 (en)
DE (1) DE69022442T2 (en)
NZ (1) NZ232389A (en)
PT (1) PT93044A (en)
ZA (1) ZA90865B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU621191B2 (en) * 1989-02-07 1992-03-05 Sanofi Aminalkoxyphenyl derivatives, process for their preparation and compositions containing them
AU624475B2 (en) * 1989-02-07 1992-06-11 Sanofi Cycloaminoalkoxyphenyl derivatives, a process for their preparation as well as the compositions containing them

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2692574B1 (en) * 1992-06-23 1995-06-23 Sanofi Elf 4-HYDROXY BENZENETHIO DERIVATIVES, THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF AMINOALKOXYBENZENESULFONYL DERIVATIVES.
FR2692578B1 (en) * 1992-06-23 1995-06-30 Sanofi Elf INDOLIZIN DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF FOR THE PREPARATION OF AMINOALKOXYBENZENESULFONYL-INDOLIZINE COMPOUNDS WITH PHARMACEUTICAL ACTIVITY.
FR2708604B1 (en) * 1993-07-30 1995-10-20 Sanofi Elf Use of benzenesulfonyl-indole derivatives for the preparation of medicaments.
DE4422517A1 (en) * 1994-06-28 1996-01-04 Dresden Arzneimittel New (2- (3,4-dimethoxy-phenyl) -ethyl) - (2-phenoxy-ethyl) -amines, processes for their preparation and their use as medicines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117128A (en) * 1976-08-03 1978-09-26 Smithkline Corporation Sulfonyl benzofurans and benzothiophenes having coronary vasodilator activity
FR2594438B1 (en) * 1986-02-14 1990-01-26 Labaz Sanofi Nv INDOLIZINE DERIVATIVES, THEIR PREPARATION PROCESS AND THE COMPOSITIONS CONTAINING SAME
IL87181A (en) * 1987-08-07 1993-08-18 Sanofi Sa Aminoalkoxyphenyl derivatives, their preparation and pharmaceutical and veterinary compositions containing them
FR2642755B1 (en) * 1989-02-07 1993-11-05 Sanofi

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU621191B2 (en) * 1989-02-07 1992-03-05 Sanofi Aminalkoxyphenyl derivatives, process for their preparation and compositions containing them
AU624475B2 (en) * 1989-02-07 1992-06-11 Sanofi Cycloaminoalkoxyphenyl derivatives, a process for their preparation as well as the compositions containing them

Also Published As

Publication number Publication date
CA2008985A1 (en) 1990-08-06
DE69022442D1 (en) 1995-10-26
EP0382618B1 (en) 1995-09-20
EP0382618A2 (en) 1990-08-16
EP0382618A3 (en) 1991-11-13
AU638692B2 (en) 1993-07-08
ZA90865B (en) 1991-10-30
JPH02250862A (en) 1990-10-08
DE69022442T2 (en) 1996-05-09
NZ232389A (en) 1991-08-27
ATE128137T1 (en) 1995-10-15
PT93044A (en) 1990-08-31

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