NZ222110A - Therapeutic powder form of spray-dried acetaminophen which includes ethyl cellulose and colloidal silica, and solid pharmaceutical dosage forms comprising the powder - Google Patents
Therapeutic powder form of spray-dried acetaminophen which includes ethyl cellulose and colloidal silica, and solid pharmaceutical dosage forms comprising the powderInfo
- Publication number
- NZ222110A NZ222110A NZ222110A NZ22211087A NZ222110A NZ 222110 A NZ222110 A NZ 222110A NZ 222110 A NZ222110 A NZ 222110A NZ 22211087 A NZ22211087 A NZ 22211087A NZ 222110 A NZ222110 A NZ 222110A
- Authority
- NZ
- New Zealand
- Prior art keywords
- powder
- spray
- dosage forms
- colloidal silica
- ethyl cellulose
- Prior art date
Links
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 title abstract 6
- 239000000843 powder Substances 0.000 title abstract 4
- 229960005489 paracetamol Drugs 0.000 title abstract 3
- 239000001856 Ethyl cellulose Substances 0.000 title abstract 2
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 title abstract 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008119 colloidal silica Substances 0.000 title abstract 2
- 239000002552 dosage form Substances 0.000 title abstract 2
- 229920001249 ethyl cellulose Polymers 0.000 title abstract 2
- 235000019325 ethyl cellulose Nutrition 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title 1
- 239000007910 chewable tablet Substances 0.000 abstract 1
- 238000001694 spray drying Methods 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Glanulating (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/921,558 US4771077A (en) | 1986-10-21 | 1986-10-21 | Spray dried acetaminophen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ222110A true NZ222110A (en) | 1989-07-27 |
Family
ID=25445622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ222110A NZ222110A (en) | 1986-10-21 | 1987-10-09 | Therapeutic powder form of spray-dried acetaminophen which includes ethyl cellulose and colloidal silica, and solid pharmaceutical dosage forms comprising the powder |
Country Status (14)
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946684A (en) * | 1989-06-20 | 1990-08-07 | American Home Products Corporation | Fast dissolving dosage forms |
| US5037658A (en) * | 1989-09-14 | 1991-08-06 | Hoechst-Roussel Pharmaceuticals, Inc. | Direct dry compressible acetaminophen composition |
| US5198228A (en) * | 1989-09-14 | 1993-03-30 | Hoechst-Roussel Pharmaceuticals Inc. | Direct dry compressible acetaminophen tablet |
| US5130140A (en) * | 1989-09-14 | 1992-07-14 | Hoeschst-Roussel Pharmaceuticals Inc. | Method of making direct dry compressible acetaminophen composition |
| EP0421582A1 (en) * | 1989-10-03 | 1991-04-10 | Warner-Lambert Company | Chewable spray dried spheroidal microcapsules and polymer coated microcapsules and method for preparing same |
| US5251430A (en) | 1990-08-10 | 1993-10-12 | Honda Giken Kogyo Kabushiki Kaisha | Cutter and housing assembly for lawn mower |
| GB2257363B (en) * | 1991-01-30 | 1994-09-28 | Wellcome Found | Water dispersible tablets containing acyclovir |
| US5629016A (en) * | 1991-01-30 | 1997-05-13 | Glaxo Wellcome Inc. | Water-dispersible tablets |
| GB9215908D0 (en) * | 1992-07-27 | 1992-09-09 | Wellcome Found | Water dispersible tablets |
| EP1166801A1 (en) * | 1993-06-04 | 2002-01-02 | Warner-Lambert Company | Preparations containing silicon dioxide to improve the taste thereof |
| US5698226A (en) * | 1993-07-13 | 1997-12-16 | Glaxo Wellcome Inc. | Water-dispersible tablets |
| CA2169371A1 (en) * | 1993-08-13 | 1995-02-23 | Thomas A. Alexander | Hydrolyzed gelatin as a flavor enhancer in a chewable tablet |
| AUPO637197A0 (en) * | 1997-04-23 | 1997-05-15 | F.H. Faulding & Co. Limited | Taste-masked pharmaceutical compositions |
| AUPN940796A0 (en) * | 1996-04-23 | 1996-05-16 | F.H. Faulding & Co. Limited | Taste masked pharmaceutical compositions |
| AU751497B2 (en) * | 1996-04-23 | 2002-08-15 | Mayne Pharma International Pty Ltd | Taste masked pharmaceutical compositions |
| US20040162273A1 (en) * | 2003-01-23 | 2004-08-19 | The Procter & Gamble Company | Powder pharmaceutical compositions |
| JP5026675B2 (ja) * | 2005-03-08 | 2012-09-12 | 洋文 竹内 | 錠剤、およびその製造方法 |
| US20060292214A1 (en) * | 2005-06-03 | 2006-12-28 | Elan Pharma International Limited | Nanoparticulate acetaminophen formulations |
| GB2443793B (en) * | 2006-04-05 | 2010-12-01 | Reckitt Benckiser Healthcare | Product, method of manufacture and use |
| US11931227B2 (en) | 2013-03-15 | 2024-03-19 | Cook Medical Technologies Llc | Bimodal treatment methods and compositions for gastrointestinal lesions with active bleeding |
| US20210106717A1 (en) * | 2019-10-10 | 2021-04-15 | Cook Medical Technologies Llc | Bonded powders for the treatment of bodily lesions |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5420572B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1973-04-27 | 1979-07-24 | ||
| US4013785A (en) * | 1975-03-21 | 1977-03-22 | Bristol-Myers Company | Apap tablet containing fumed silica and process for manufacturing same |
| IE45770B1 (en) * | 1976-10-06 | 1982-11-17 | Wyeth John & Brother Ltd | Pharmaceutical dosage forms |
| ATE17650T1 (de) * | 1980-05-20 | 1986-02-15 | Mallinckrodt Inc | Trockenpulverisierte n-acetyl-p-aminophenolzusammensetzungenund verfahren zu deren herstellung. |
| JPS58172311A (ja) * | 1982-04-02 | 1983-10-11 | Kodama Kk | 持続性製剤及びその製法 |
| DE3306012A1 (de) * | 1983-02-22 | 1984-08-23 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung eines freifliessenden paracetamol-granulats |
| US4600579A (en) * | 1983-06-07 | 1986-07-15 | Mallinckrodt, Inc. | N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same |
| US4533674A (en) * | 1983-10-24 | 1985-08-06 | Basf Wyandotte Corporation | Process for preparing a sugar and starch free spray-dried vitamin C powder containing 90 percent ascorbic acid |
| KR850700213A (ko) * | 1984-02-08 | 1985-12-26 | 제이.데스몬드 다비스 | 아세트 아미노펜 젤라틴 캡슐 |
| US4710519A (en) * | 1985-09-30 | 1987-12-01 | Basf Corporation | Process for preparing spray dried acetaminophen powder and the powder prepared thereby |
-
1986
- 1986-10-21 US US06/921,558 patent/US4771077A/en not_active Expired - Lifetime
-
1987
- 1987-10-07 ZA ZA877542A patent/ZA877542B/xx unknown
- 1987-10-09 NZ NZ222110A patent/NZ222110A/xx unknown
- 1987-10-09 AU AU79510/87A patent/AU590980B2/en not_active Expired
- 1987-10-09 CA CA000548996A patent/CA1298199C/en not_active Expired - Lifetime
- 1987-10-13 IE IE274987A patent/IE61950B1/en not_active IP Right Cessation
- 1987-10-20 ES ES198787309253T patent/ES2032295T3/es not_active Expired - Lifetime
- 1987-10-20 JP JP62266140A patent/JP2550363B2/ja not_active Expired - Fee Related
- 1987-10-20 KR KR1019870011624A patent/KR950013752B1/ko not_active Expired - Fee Related
- 1987-10-20 EP EP87309253A patent/EP0265226B1/en not_active Expired - Lifetime
- 1987-10-20 DE DE8787309253T patent/DE3778825D1/de not_active Expired - Lifetime
- 1987-10-20 AT AT87309253T patent/ATE75602T1/de not_active IP Right Cessation
- 1987-10-21 PH PH35967A patent/PH24376A/en unknown
-
1992
- 1992-06-29 GR GR920401373T patent/GR3005045T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0265226A3 (en) | 1989-07-19 |
| AU590980B2 (en) | 1989-11-23 |
| ZA877542B (en) | 1989-05-30 |
| AU7951087A (en) | 1988-04-28 |
| JP2550363B2 (ja) | 1996-11-06 |
| IE61950B1 (en) | 1994-11-30 |
| KR950013752B1 (ko) | 1995-11-15 |
| GR3005045T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-05-24 |
| DE3778825D1 (de) | 1992-06-11 |
| US4771077A (en) | 1988-09-13 |
| JPS63112515A (ja) | 1988-05-17 |
| IE872749L (en) | 1988-04-21 |
| ES2032295T3 (es) | 1993-02-01 |
| PH24376A (en) | 1990-06-13 |
| KR880004805A (ko) | 1988-06-27 |
| EP0265226B1 (en) | 1992-05-06 |
| EP0265226A2 (en) | 1988-04-27 |
| CA1298199C (en) | 1992-03-31 |
| ATE75602T1 (de) | 1992-05-15 |
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