NZ219779A - 3-methyl-5-(3-(4,4-diphenylpiperid-1-yl)-propyl)(+)-1,4 -dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5 dicarboxylate, its salts, preparation and medicaments - Google Patents

3-methyl-5-(3-(4,4-diphenylpiperid-1-yl)-propyl)(+)-1,4 -dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5 dicarboxylate, its salts, preparation and medicaments

Info

Publication number
NZ219779A
NZ219779A NZ219779A NZ21977987A NZ219779A NZ 219779 A NZ219779 A NZ 219779A NZ 219779 A NZ219779 A NZ 219779A NZ 21977987 A NZ21977987 A NZ 21977987A NZ 219779 A NZ219779 A NZ 219779A
Authority
NZ
New Zealand
Prior art keywords
diphenylpiperid
dicarboxylate
nitrophenyl
medicaments
dihydro
Prior art date
Application number
NZ219779A
Inventor
Manfrid Eltze
Dieter Flockerzi
Kurt Klemm
Bernhard Kohl
Norbert Kolassa
Karl Sanders
Christian Schudt
Wolf-Rudiger Ulrich
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of NZ219779A publication Critical patent/NZ219779A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NZ219779A 1986-03-27 1987-03-26 3-methyl-5-(3-(4,4-diphenylpiperid-1-yl)-propyl)(+)-1,4 -dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5 dicarboxylate, its salts, preparation and medicaments NZ219779A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH126386 1986-03-27

Publications (1)

Publication Number Publication Date
NZ219779A true NZ219779A (en) 1990-03-27

Family

ID=4206306

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ219779A NZ219779A (en) 1986-03-27 1987-03-26 3-methyl-5-(3-(4,4-diphenylpiperid-1-yl)-propyl)(+)-1,4 -dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5 dicarboxylate, its salts, preparation and medicaments

Country Status (12)

Country Link
EP (1) EP0240828A1 (en)
JP (1) JPS62270528A (en)
KR (1) KR870008872A (en)
CN (1) CN87102402A (en)
AU (1) AU574604B2 (en)
DK (1) DK142287A (en)
FI (1) FI871327A (en)
HU (1) HU196791B (en)
NO (1) NO871284L (en)
NZ (1) NZ219779A (en)
PT (1) PT84566B (en)
ZA (1) ZA872189B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0296316B1 (en) * 1987-03-27 1993-09-01 Byk Gulden Lomberg Chemische Fabrik GmbH 1,4-dihydropyridine enantiomers
HU206181B (en) * 1988-02-19 1992-09-28 Byk Gulden Lomberg Chem Fab Process for producing pharmaceutical compositions comprising optically pure r-(+)-niguldipin and its derivatives and suitable for treating tumoros diseases
DE4125271A1 (en) * 1991-07-31 1993-02-11 Bayer Ag NEW N-ALKYLATED 1,4-DIHYDROPYRIDINDICARBONIC ACID ESTERS
US6015819A (en) 1992-11-13 2000-01-18 Synaptic Pharmaceutical Corporation Use of alpha-1C specific compounds to treat benign prostatic hyperplasia
GB9405833D0 (en) * 1994-03-24 1994-05-11 Pfizer Ltd Separation of the enantiomers of amlodipine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2935451A1 (en) * 1979-09-01 1981-03-19 Bayer Ag, 5090 Leverkusen OPTICALLY ACTIVE 1,4-DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT
US4603135A (en) * 1983-10-17 1986-07-29 Takeda Chemical Industries, Ltd. Substituted piperazinyl alkyl esters of 2-amino-4-aryl-1,4-dihydro-6-alkyl-3,5-pyridinedicarboxylates
FI83957C (en) * 1984-09-28 1991-09-25 Byk Gulden Lomberg Chem Fab FOERFARANDE FOER FRAMSTAELLNING AV NYA, TERAPEUTISKT ANVAENDBARA DIARYLFOERENINGAR.
DK114587A (en) * 1986-03-12 1987-09-13 Byk Gulden Lomberg Chem Fab MONOCYCLIC ESTER DERIVATIVES

Also Published As

Publication number Publication date
EP0240828A1 (en) 1987-10-14
DK142287D0 (en) 1987-03-19
KR870008872A (en) 1987-10-21
FI871327A (en) 1987-09-28
PT84566B (en) 1989-11-30
AU7052587A (en) 1987-12-10
AU574604B2 (en) 1988-07-07
ZA872189B (en) 1987-11-25
FI871327A0 (en) 1987-03-26
JPS62270528A (en) 1987-11-24
NO871284L (en) 1987-09-28
HU196791B (en) 1989-01-30
CN87102402A (en) 1987-10-07
HUT43588A (en) 1987-11-30
NO871284D0 (en) 1987-03-26
PT84566A (en) 1987-04-01
DK142287A (en) 1987-09-28

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