NZ190723A - Acyl (bicyclic aryl) amino alkanoic acids pharmaceutical compositions - Google Patents

Acyl (bicyclic aryl) amino alkanoic acids pharmaceutical compositions

Info

Publication number
NZ190723A
NZ190723A NZ190723A NZ19072379A NZ190723A NZ 190723 A NZ190723 A NZ 190723A NZ 190723 A NZ190723 A NZ 190723A NZ 19072379 A NZ19072379 A NZ 19072379A NZ 190723 A NZ190723 A NZ 190723A
Authority
NZ
New Zealand
Prior art keywords
bicyclic aryl
signifies
liver
acyl
pharmaceutical compositions
Prior art date
Application number
NZ190723A
Inventor
W Krastinat
R Riedel
H Wolf
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of NZ190723A publication Critical patent/NZ190723A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/12Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group, wherein Cn means a carbon skeleton not containing a ring; Thio analogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Agronomy & Crop Science (AREA)
  • Biophysics (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Acyl (bicyclic aryl) - aminoalkanoic acids of the general formula I <IMAGE> in which R<1> signifies an aliphatic or alicyclic hydrocarbon radical or an optionally substituted phenyl group, A signifies an optionally substituted and/or hydrogenated bicyclic aryl radical and n signifies 3, 4 or 5, as well as their salts of inorganic or organic bases exert in warm-blooded animals a protective action on the stomach and an increase in the pancreatic secretion, and in addition they exert an action on the liver and bile. Furthermore, they bring about an inhibition of the formation of glucose from lactate and pyruvate in the liver. They are suitable for the treatment and prophylaxis of diseases which a@ attributed to disorders of the stomach or intestine or to reduced performances of the pancreas, bile and/or liver, or the treatment of diabetes. Processes for the production of the compounds and suitable pharmaceutical products are given.
NZ190723A 1978-06-14 1979-06-14 Acyl (bicyclic aryl) amino alkanoic acids pharmaceutical compositions NZ190723A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH650578 1978-06-14

Publications (1)

Publication Number Publication Date
NZ190723A true NZ190723A (en) 1981-12-15

Family

ID=4310667

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ190723A NZ190723A (en) 1978-06-14 1979-06-14 Acyl (bicyclic aryl) amino alkanoic acids pharmaceutical compositions

Country Status (17)

Country Link
EP (1) EP0006217B1 (en)
JP (1) JPS554375A (en)
AT (1) ATE797T1 (en)
AU (1) AU525311B2 (en)
BE (1) BE876934A (en)
DE (2) DE2923698A1 (en)
DK (1) DK245079A (en)
ES (1) ES481493A1 (en)
FR (1) FR2432502A1 (en)
GB (1) GB2024814A (en)
GR (1) GR65664B (en)
HU (1) HU180209B (en)
IL (1) IL57553A0 (en)
NZ (1) NZ190723A (en)
PL (1) PL216291A1 (en)
PT (1) PT69763A (en)
ZA (1) ZA792944B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4440941A (en) * 1980-12-22 1984-04-03 Usv Pharmaceutical Corporation Aroyl-aminoacids, amides and esters thereof
US4521607A (en) * 1981-02-27 1985-06-04 Takeda Chemical Industries, Ltd. Chromanyl glycines
US4686232A (en) * 1983-02-28 1987-08-11 Sumitomo Chemical Company, Limited Fungicidal aniline derivatives
JPS61185140A (en) * 1985-02-08 1986-08-18 ゼニヤ海洋サ−ビス株式会社 Apparatus for preventing generation of red tide
ATE99698T1 (en) * 1985-10-14 1994-01-15 Nippon Zoki Pharmaceutical Co PEPTIDES.
JPS62205095A (en) * 1986-03-04 1987-09-09 Toyo Jozo Co Ltd Novel physiologically active substance aldostatin and production thereof
JPH0226466U (en) * 1988-08-03 1990-02-21

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697563A (en) * 1970-06-29 1972-10-10 Inst Chemioterapico Italiano S (3,4,5-trimethoxy-benzamido)-alkanoic acids for prophylaxis and treatment of cardiac disorders

Also Published As

Publication number Publication date
ZA792944B (en) 1980-06-25
GB2024814A (en) 1980-01-16
BE876934A (en) 1979-12-12
PL216291A1 (en) 1980-03-24
DE2962385D1 (en) 1982-05-06
ES481493A1 (en) 1980-03-01
EP0006217A1 (en) 1980-01-09
FR2432502A1 (en) 1980-02-29
PT69763A (en) 1979-07-01
JPS554375A (en) 1980-01-12
IL57553A0 (en) 1979-10-31
EP0006217B1 (en) 1982-03-31
HU180209B (en) 1983-02-28
ATE797T1 (en) 1982-04-15
DE2923698A1 (en) 1980-01-03
AU525311B2 (en) 1982-10-28
DK245079A (en) 1979-12-15
AU4797779A (en) 1979-12-20
GR65664B (en) 1980-10-16

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