NZ183462A - Prostanoic ergolin-8-ylalkyl esters, thioesters and amides: preparation and pharmaceutical compositions - Google Patents

Prostanoic ergolin-8-ylalkyl esters, thioesters and amides: preparation and pharmaceutical compositions

Info

Publication number
NZ183462A
NZ183462A NZ183462A NZ18346277A NZ183462A NZ 183462 A NZ183462 A NZ 183462A NZ 183462 A NZ183462 A NZ 183462A NZ 18346277 A NZ18346277 A NZ 18346277A NZ 183462 A NZ183462 A NZ 183462A
Authority
NZ
New Zealand
Prior art keywords
ergolin
ylalkyl
prostanoic
thioesters
amides
Prior art date
Application number
NZ183462A
Inventor
R Wenger
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of NZ183462A publication Critical patent/NZ183462A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/70Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32Nitrogen atom
    • C07D473/34Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NZ183462A 1976-04-27 1977-02-28 Prostanoic ergolin-8-ylalkyl esters, thioesters and amides: preparation and pharmaceutical compositions NZ183462A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH526876 1976-04-27

Publications (1)

Publication Number Publication Date
NZ183462A true NZ183462A (en) 1979-10-25

Family

ID=4290745

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ183462A NZ183462A (en) 1976-04-27 1977-02-28 Prostanoic ergolin-8-ylalkyl esters, thioesters and amides: preparation and pharmaceutical compositions

Country Status (13)

Country Link
JP (1) JPS52131600A (en)
BE (1) BE852055A (en)
DE (1) DE2707915A1 (en)
DK (1) DK75177A (en)
FI (1) FI770572A (en)
FR (2) FR2353549A1 (en)
GB (1) GB1577647A (en)
IL (1) IL51561A0 (en)
NL (1) NL7702221A (en)
NZ (1) NZ183462A (en)
PT (1) PT66269B (en)
SU (1) SU741794A3 (en)
ZA (1) ZA771215B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196598B (en) * 1986-04-25 1988-12-28 Richter Gedeon Vegyeszet Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds

Also Published As

Publication number Publication date
DK75177A (en) 1977-10-28
NL7702221A (en) 1977-10-31
DE2707915A1 (en) 1977-11-17
IL51561A0 (en) 1977-04-29
PT66269A (en) 1977-04-01
GB1577647A (en) 1980-10-29
BE852055A (en) 1977-09-05
SU741794A3 (en) 1980-06-15
ZA771215B (en) 1978-10-25
FI770572A (en) 1977-10-28
PT66269B (en) 1978-11-07
FR2353549A1 (en) 1977-12-30
FR2355837A1 (en) 1978-01-20
JPS52131600A (en) 1977-11-04

Similar Documents

Publication Publication Date Title
IL51450A (en) Cefuroxime esters,their preparation and pharmaceutical compositions containing them
NZ185986A (en) 2-oxa-bicyclic prostag-landins and pharmaceutical compositions
IL52258A (en) Monic acid esters,their preparation and pharmaceutical compositions containing them
NZ183551A (en) Aminochromanols and pharmaceutical compositions containingthem
NZ183150A (en) 7-aminothiazolyl-iminoa-cetamido-cephalosporin derivatives and pharmaceutical compositions
NZ185358A (en) Spiro-hydantoins and pharmaceutical compositions
NZ187849A (en) Prostaglandin i derivatives and pharmaceutical compositions
PH16512A (en) N-(phenylalkylamino-alkyl)-dihydroisoquinolinones,pharmaceutical compositions and methods employing them
NZ184428A (en) N-acyl-l-alanyl-aminoacyl-amides untermediates and pharmaceutical compositions
IL49325A0 (en) Novel prostaglandin derivatives,their preparation and pharmaceutical compositions containing them
NZ184263A (en) N-(amino-alkyl-amino)-benzamides and pharmaceutical compositions
NZ186119A (en) 7-alkoxycarbonyl-6-alkyl/halo-17-hydoxy-3-oxo-17 -pregn-4-ene-21-carboxylic acid derivatives and pharmaceutical compositions
NZ184755A (en) 2-benzylpyrrolidine derivatives and pharmaceutical compositions
NZ184912A (en) 2-phenylamino-imidazolines and pharmaceutical compositions
IL51428A (en) 3-substituted-4-aminoalkoxy-5,6-condensed ring-(2h)-pyran-2-ones,their preparation and pharmaceutical compositions containing them
NZ184102A (en) Derivatives of benzenesulphonylurea,and pharmaceutical compositions
NZ184103A (en) Fenzodioxole derivatives and pharmaceutical compositions
NZ185539A (en) Cis-4a-aryl-2-substituted-2,3,4,4a,5,6,7,7a-octa hydro-1h-2-pyrindines and pharmaceutical compositions
NZ183549A (en) Amidinopencillanoyloxy-alkyl-amoxycillinates and pharmaceutical compositions
NZ186059A (en) 3-sulphamoyl-5-pyrrolylal-kylbenzoic acid derivatives and pharmaceutical compositions
IL53552A (en) 1-piperazinopropanol esters,their preparation and pharmaceutical compositions containing them
NZ183462A (en) Prostanoic ergolin-8-ylalkyl esters, thioesters and amides: preparation and pharmaceutical compositions
IL53342A (en) Monocyclic -lactams,their preparation and pharmaceutical compositions containing -lactams having anitbacterial activite
NZ183756A (en) Bis-penicillanoyloxy-alkanes and pharmaceutical compositions
NZ184367A (en) 2-vinyl-chromone derivatives and pharmaceutical compositions