NO996496L - (S) 2-methylamino-2-phenyl-n-butyl 3,4,5-trimethoxybenzoate and its use in the treatment of chronic pain - Google Patents

(S) 2-methylamino-2-phenyl-n-butyl 3,4,5-trimethoxybenzoate and its use in the treatment of chronic pain

Info

Publication number
NO996496L
NO996496L NO996496A NO996496A NO996496L NO 996496 L NO996496 L NO 996496L NO 996496 A NO996496 A NO 996496A NO 996496 A NO996496 A NO 996496A NO 996496 L NO996496 L NO 996496L
Authority
NO
Norway
Prior art keywords
trimethoxybenzoate
methylamino
phenyl
butyl
treatment
Prior art date
Application number
NO996496A
Other languages
Norwegian (no)
Other versions
NO996496D0 (en
Inventor
Svein Gunwald Dahl
Henri Jacobelli
Agnes Grouhel
Francois Joseph Roman
Original Assignee
Parke Davis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parke Davis filed Critical Parke Davis
Publication of NO996496D0 publication Critical patent/NO996496D0/en
Publication of NO996496L publication Critical patent/NO996496L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C219/14—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Det er beskrevet optisk rent (S) 2-metylamino-2-fenyl-n-butyl 3,4,5- trimetoksybenzoat for anvendelse ved behandling av kronisk smerte og som har formel (I). Det er også beskrevet fremgangsmåte for anvendelse av forbindelsene av formel (l) og farmasøytisk preparater som inneholder forbindelsen av formel (I).Optically pure (S) 2-methylamino-2-phenyl-n-butyl 3,4,5-trimethoxybenzoate is disclosed for use in the treatment of chronic pain and having formula (I). Methods are also disclosed for using the compounds of formula (I) and pharmaceutical compositions containing the compound of formula (I).

NO996496A 1997-06-30 1999-12-27 (S) 2-methylamino-2-phenyl-n-butyl 3,4,5-trimethoxybenzoate and its use in the treatment of chronic pain NO996496L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9708323A FR2765218B1 (en) 1997-06-30 1997-06-30 2 (METHYLAMINO-2-PHENYL-N- BUTYL) 3,4,5-TRIMETHOXYBENZOATE (S), ITS APPLICATION TO THE TREATMENT OF CHRONIC PAIN
PCT/EP1998/003825 WO1999001417A1 (en) 1997-06-30 1998-06-23 (S) 2-METHYLAMINO-2-PHENYL-n-BUTYL 3,4,5-TRIMETHOXYBENZOATE, ITS APPLICATION TO THE TREATMENT OF CHRONIC PAIN

Publications (2)

Publication Number Publication Date
NO996496D0 NO996496D0 (en) 1999-12-27
NO996496L true NO996496L (en) 1999-12-27

Family

ID=9508729

Family Applications (1)

Application Number Title Priority Date Filing Date
NO996496A NO996496L (en) 1997-06-30 1999-12-27 (S) 2-methylamino-2-phenyl-n-butyl 3,4,5-trimethoxybenzoate and its use in the treatment of chronic pain

Country Status (16)

Country Link
EP (1) EP0993436A1 (en)
JP (1) JP2002508776A (en)
KR (1) KR20010014294A (en)
AU (1) AU731887B2 (en)
BR (1) BR9810387A (en)
CA (1) CA2285479A1 (en)
FR (1) FR2765218B1 (en)
HU (1) HUP0003023A3 (en)
IL (1) IL133398A0 (en)
IS (1) IS5324A (en)
MX (1) MXPA99009120A (en)
NO (1) NO996496L (en)
NZ (1) NZ500212A (en)
PL (1) PL337665A1 (en)
WO (1) WO1999001417A1 (en)
ZA (1) ZA985668B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1110549A1 (en) 1999-12-23 2001-06-27 Warner-Lambert Company Use of trimebutine for treating pain
FR2927076B1 (en) 2008-01-31 2010-03-26 Oroxcell 2-AMINO-2-PHENYL-ALKANOL DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2948660B1 (en) 2009-07-30 2011-08-19 Oroxcell 2-AMINO-2-PHENYL-ALKANOL DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
AU2013203698A1 (en) * 2012-03-12 2013-10-03 Gicare Pharma Inc. Novel sulfonate-based trimebutine salts
RU2752086C1 (en) * 2020-04-27 2021-07-22 Общество С Ограниченной Ответственностью "Валента-Интеллект" New [2-(dimethylamino)-2-phenylbutyl]-3,4,5-trimetoxybenzoate 4-methyl-2h-chromen-2-on-7-ilsulphate compound and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1434826A (en) * 1973-11-14 1976-05-05 Gallardo Antonio Sa Esters and carbamates of aminoalkanols

Also Published As

Publication number Publication date
BR9810387A (en) 2000-09-05
AU8540598A (en) 1999-01-25
JP2002508776A (en) 2002-03-19
PL337665A1 (en) 2000-08-28
KR20010014294A (en) 2001-02-26
MXPA99009120A (en) 2005-01-10
ZA985668B (en) 1999-01-25
NO996496D0 (en) 1999-12-27
CA2285479A1 (en) 1999-01-14
HUP0003023A2 (en) 2001-01-29
FR2765218A1 (en) 1998-12-31
EP0993436A1 (en) 2000-04-19
AU731887B2 (en) 2001-04-05
HUP0003023A3 (en) 2001-12-28
FR2765218B1 (en) 1999-08-13
NZ500212A (en) 2001-07-27
WO1999001417A1 (en) 1999-01-14
IS5324A (en) 1999-12-28
IL133398A0 (en) 2001-04-30

Similar Documents

Publication Publication Date Title
TR199800585T2 (en) (Methylsulfonyl)Phenyl-2-(5H)-Furanons as COX-2 Inhibitors.
ATE148130T1 (en) TYPE IV DIPEPTIDYL AMINOOPEPTIDASE INHIBITORS
SE9604786D0 (en) New compounds
GEP20012578B (en) (54) Heteroaryl Succinamides, Pharmaceutical Compositions Containing the Same and Methods for Treatment of the Diseases Caused by Metalloproteinase Activity
BR9806752A (en) Phthalazinones.
DE69735442D1 (en) ANTIDIABETIC AGENTS
WO1997030677A3 (en) Pentafluorobenzenesulfonamides and analogs
DE69523436D1 (en) Lactate dehydrogenase inhibitors containing cosmetic compositions
BR9805544C1 (en) Use of a compound.
MX9605741A (en) (r)-(-)-2-{n-[4-(1,1-dioxide-3-oxo-2,3-dihydro-benzisotiazole-2-yl)-buty l]-aminomethyl}-cromane crystalline chlorhydrate.
YU66000A (en) Antipicornaviral compounds, their preparation and use
WO1992019617A3 (en) Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
ATE267187T1 (en) DIHYDROBENZOFURANES AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS
DE69405919D1 (en) Compositions for the treatment of keratin fibers
NO995431L (en) Substituted 3,3-diamino-2-propenitriles, their preparation and use
CA2266759A1 (en) 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase
NO20000519L (en) 2-acylaminopropanamines as tachykinin receptor antagonists
NO996496L (en) (S) 2-methylamino-2-phenyl-n-butyl 3,4,5-trimethoxybenzoate and its use in the treatment of chronic pain
DE69613395D1 (en) SULFUR-CONTAINING DI-TER-BUTYLPHENOL COMPOUNDS USED AS AN ANTI-FLAMMING AGENT
BR0012921A (en) Calcally Compounds
WO1996031208A3 (en) Use of substituted piperidine or pyrrolidine compounds for treating sigma-receptor modulated disorders
IT1288399B1 (en) MEDICATION FOR THE THERAPEUTIC TREATMENT OF AGE-RELATED MACULOPATHY, NON-AGE-RELATED MACULOPATHY AND FOR PROPHYLAXIS
NO982562D0 (en) Composition for the treatment of pain
NO923266L (en) Hexahydrobenzo (F) QUINOLINONER
ES2170377T3 (en) COMPOSITION CONTAINING QUITOSANA.

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application