NO996173L - Overhauser magnetisk resonans avbildningsmetode som omfatter ex-vivo polarisering av et MRI kontrastmiddel - Google Patents
Overhauser magnetisk resonans avbildningsmetode som omfatter ex-vivo polarisering av et MRI kontrastmiddelInfo
- Publication number
- NO996173L NO996173L NO996173A NO996173A NO996173L NO 996173 L NO996173 L NO 996173L NO 996173 A NO996173 A NO 996173A NO 996173 A NO996173 A NO 996173A NO 996173 L NO996173 L NO 996173L
- Authority
- NO
- Norway
- Prior art keywords
- magnetic resonance
- contrast agent
- resonance imaging
- imaging method
- mri contrast
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/20—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations containing free radicals, e.g. trityl radical for overhauser
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/62—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using double resonance
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Signal Processing (AREA)
- High Energy & Nuclear Physics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9712984.5A GB9712984D0 (en) | 1997-06-19 | 1997-06-19 | Method |
GBGB9800158.9A GB9800158D0 (en) | 1998-01-05 | 1998-01-05 | Method |
PCT/GB1998/001814 WO1998058272A1 (en) | 1997-06-19 | 1998-06-19 | Overhauser magnetic resonance imaging (ormi) method comprising ex vivo polarization of a magnetic resonance (mr) imaging agent |
Publications (2)
Publication Number | Publication Date |
---|---|
NO996173D0 NO996173D0 (no) | 1999-12-14 |
NO996173L true NO996173L (no) | 2000-02-15 |
Family
ID=26311767
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO996173A NO996173L (no) | 1997-06-19 | 1999-12-14 | Overhauser magnetisk resonans avbildningsmetode som omfatter ex-vivo polarisering av et MRI kontrastmiddel |
Country Status (8)
Country | Link |
---|---|
US (1) | US6311086B1 (no) |
EP (1) | EP0990168A1 (no) |
JP (1) | JP2002508687A (no) |
CN (1) | CN1269015A (no) |
AU (1) | AU8119298A (no) |
CA (1) | CA2290808A1 (no) |
NO (1) | NO996173L (no) |
WO (1) | WO1998058272A1 (no) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6346229B1 (en) | 1998-03-18 | 2002-02-12 | Medi-Physics, Inc. | Methods for imaging pulmonary and cardiac vasculature and evaluating blood flow using dissolved polarized 129Xe |
EP1445622A3 (en) | 1998-06-17 | 2004-12-15 | Medi-Physics, Inc. | Hyperpolarized gas transport device |
US6286319B1 (en) | 1998-09-30 | 2001-09-11 | Medi-Physics, Inc. | Meted hyperpolarized noble gas dispensing methods and associated devices |
US6237363B1 (en) | 1998-09-30 | 2001-05-29 | Medi-Physics, Inc. | Hyperpolarized noble gas extraction methods masking methods and associated transport containers |
US6523356B2 (en) | 1998-09-30 | 2003-02-25 | Medi-Physics, Inc. | Meted hyperpolarized noble gas dispensing methods and associated devices |
US6284222B1 (en) | 1998-11-03 | 2001-09-04 | Medi--Physics, Inc. | Hyperpolarized helium-3 microbubble gas entrapment methods |
AU4686899A (en) | 1999-02-23 | 2000-09-14 | Medi-Physics, Inc. | Portable system for monitoring the polarization level of a hyperpolarized gas during transport |
DE19911043A1 (de) * | 1999-03-12 | 2000-09-14 | Philips Corp Intellectual Pty | MR-Verfahren |
AU4598600A (en) * | 1999-05-19 | 2000-12-12 | Nycomed Imaging As | Methods of magnetic resonance imaging (mri) using contract agent solutions formed from the dissolution of hyperpolarised materials |
WO2000072031A1 (en) * | 1999-05-19 | 2000-11-30 | Nycomed Imaging As | Methods of magnetic resonance imaging (mri) using contract agent solutions formed from the dissolution of hyperpolarised materials |
US6295834B1 (en) | 1999-06-30 | 2001-10-02 | Medi-Physics, Inc. | NMR polarization monitoring coils, hyperpolarizers with same, and methods for determining the polarization level of accumulated hyperpolarized noble gases during production |
JP2003526437A (ja) | 2000-03-13 | 2003-09-09 | メディ−フィジックス・インコーポレイテッド | ガス状過分極129Xeの直接注射を使用する診断処置並びに関連するシステムおよび生成物 |
GB0009353D0 (en) | 2000-04-14 | 2000-05-31 | Nycomed Imaging As | Method |
GB0014463D0 (en) * | 2000-06-14 | 2000-08-09 | Nycomed Amersham Plc | NMR Method |
JP2002071596A (ja) * | 2000-08-25 | 2002-03-08 | Yamagata Public Corp For The Development Of Industry | 電子スピン共鳴の計測方法および計測装置 |
ES2269507T3 (es) * | 2000-11-03 | 2007-04-01 | Amersham Health As | Procedimiento y dispositivo de disolucion de material solido hiperpolarizado para analisis de rmn. |
GB0122049D0 (en) * | 2001-09-12 | 2001-10-31 | Nycomed Imaging As | Method |
US6946835B1 (en) * | 2002-02-09 | 2005-09-20 | Intematix Corporation | Spatially resolved spin resonance detection |
US7148683B2 (en) | 2001-10-25 | 2006-12-12 | Intematix Corporation | Detection with evanescent wave probe |
US6693426B1 (en) * | 2002-02-09 | 2004-02-17 | Intematix Corporation | Spatially resolved spin resonance detection |
NO20023357D0 (no) | 2002-04-19 | 2002-07-11 | Amersham Health As | Blanding |
GB0219953D0 (en) * | 2002-08-29 | 2002-10-02 | Amersham Health R & D Ab | An arrangement and a method for providing contrast agents |
DE10249239A1 (de) * | 2002-10-23 | 2004-05-06 | Philips Intellectual Property & Standards Gmbh | Magnetresonanz-Bildgerät mit elektrischer Zusatzeinrichtung |
NO20025124D0 (no) | 2002-10-25 | 2002-10-25 | Amersham Health As | Metode |
JP4890242B2 (ja) * | 2003-04-15 | 2012-03-07 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 検査エリアにおける状態変数の空間分解を決定する装置及び方法 |
US7351402B2 (en) * | 2003-08-21 | 2008-04-01 | Massachusetts Institute Of Technology | Polarizing agents for dynamic nuclear polarization |
US9023320B2 (en) | 2004-07-30 | 2015-05-05 | Ge Healthcare As | Method of producing a composition, composition and its use |
US7199584B2 (en) * | 2005-06-07 | 2007-04-03 | Research Foundation Of The City University Of New York | Method and apparatus for high resolution nuclear magnetic resonance imaging and spectroscopy |
US20070025918A1 (en) * | 2005-07-28 | 2007-02-01 | General Electric Company | Magnetic resonance imaging (MRI) agents: water soluble carbon-13 enriched fullerene and carbon nanotubes for use with dynamic nuclear polarization |
EP1940475A4 (en) | 2005-09-28 | 2010-05-26 | Harvard College | HYPERPOLARIZED SOLID MATERIALS WITH LONG SPIN RECOVERY TIMES FOR USE AS IMAGING MEANS IN MAGNETIC RESONANCE TOMOGRAPHY |
WO2007044867A2 (en) * | 2005-10-11 | 2007-04-19 | Huntington Medical Research Institutes | Imaging agents and methods of use thereof |
ES2375089T3 (es) * | 2005-12-01 | 2012-02-24 | Ge Healthcare As | Procedimiento de la polarización nuclear dinámica(dnp) que usa un radical tritilo y un ión metálico paramagnético. |
CN101325977A (zh) | 2005-12-08 | 2008-12-17 | 皇家飞利浦电子股份有限公司 | 使用Overhauser增强的NMR监测体内药物释放的系统和方法 |
US8703102B2 (en) | 2008-04-04 | 2014-04-22 | Millikelvin Technologies Llc | Systems and methods for producing hyperpolarized materials and mixtures thereof |
EP1986702A4 (en) | 2006-02-21 | 2012-12-12 | Avrum Belzer | METHODS, SYSTEMS AND COMPOSITIONS FOR HYPERPORALIZATION |
CA2650272C (en) * | 2006-05-11 | 2012-08-28 | Bell Helicopter Textron Inc. | Device and method for repairing structural components |
WO2008048714A2 (en) * | 2006-05-12 | 2008-04-24 | Massachusetts Institute Of Technology | Biradical polarizing agents for dynamic nuclear polarization |
WO2007134160A2 (en) * | 2006-05-12 | 2007-11-22 | Massachusetts Institute Of Technology | Temperature-jump dynamic nuclear polarization |
KR101502180B1 (ko) | 2006-08-30 | 2015-03-12 | 지이 헬스케어 에이에스 | 동적 핵 분극화 방법 및 이러한 방법에서 사용되는 화합물 및 조성물 |
WO2008086534A1 (en) | 2007-01-11 | 2008-07-17 | Huntington Medical Research Institutes | Imaging agents and methods of use thereof |
US7519492B2 (en) * | 2007-05-02 | 2009-04-14 | General Electric Company | Apparatus and method for fully automated closed system quality control of a substance |
GB0713074D0 (en) | 2007-07-05 | 2007-08-15 | Univ London | A method of hyperpolarising a magnetic resonance agent |
WO2009046457A2 (en) * | 2007-10-05 | 2009-04-09 | Huntington Medical Research Institutes | Imaging of genetic material with magnetic resonance |
EP2072061A1 (en) | 2007-12-19 | 2009-06-24 | GE Healthcare Limited | Composition and method for generating a metabolic profile using 13C-MR detection |
WO2009129265A1 (en) * | 2008-04-14 | 2009-10-22 | Huntington Medical Research Institutes | Methods and apparatus for pasadena hyperpolarization |
CN102083470B (zh) | 2008-05-02 | 2015-05-20 | 通用电气公司 | 应用超极化13c-丙酮酸盐,通过13c-mr检测测定丙氨酸转氨酶(alt)活性的方法 |
US20110274626A1 (en) | 2008-12-10 | 2011-11-10 | University Of York | Pulse sequencing with hyperpolarisable nuclei |
MX2011010294A (es) | 2009-04-02 | 2012-01-27 | Ge Healthcare Ltd | Uso de un medio de formacion de imagenes de resonancia magnetica que comprende 13c piruvato hiperpolarizado para la deteccion de inflamacion o infeccion. |
SG178927A1 (en) * | 2009-08-31 | 2012-04-27 | Millikelvin Technologies Llc | Systems and methods for producing hyperpolarized materials and mixtures thereof |
CA2772489A1 (en) | 2009-08-31 | 2011-03-03 | Brain Watch Ltd. | Isotopically labeled neurochemical agents and uses thereof for diagnosing conditions and disorders |
WO2011029854A1 (en) | 2009-09-10 | 2011-03-17 | Ge Healthcare Limited | 13c-mr detection using hyperpolarised 13c-fructose |
EP2348327B1 (en) * | 2010-01-18 | 2013-11-27 | Bruker BioSpin AG | Method for NMR measurements using dissolution dynamic nuclear polarization (DNP) with elimination of free radicals |
US9694090B2 (en) | 2010-04-08 | 2017-07-04 | Bracco Imaging S.P.A. | Process for preparing hyperpolarized substrates and method for MRI |
US8970217B1 (en) | 2010-04-14 | 2015-03-03 | Hypres, Inc. | System and method for noise reduction in magnetic resonance imaging |
KR101858269B1 (ko) | 2010-05-03 | 2018-05-15 | 지이 헬쓰케어 리미티드 | 락테이트 탈수소효소 활성의 측정을 위한 과분극화된 락테이트 조영제 |
EP2766050B1 (en) | 2011-10-12 | 2018-09-05 | Bracco Imaging S.p.A | Process for the preparation of hyperpolarized derivatives for use in mri analysis |
EP2788035B1 (en) | 2011-12-05 | 2016-03-09 | Bracco Imaging S.p.A | Composition comprising acetic anhydride and a gadolinium complex, and method for the use in hyperpolarisation mri analysis |
US8715621B2 (en) | 2012-03-15 | 2014-05-06 | Massachusetts Institute Of Technology | Radical polarizing agents for dynamic nuclear polarization |
WO2013167587A1 (en) | 2012-05-07 | 2013-11-14 | Albeda Innovation Aps | Intra-operative cancer diagnosis based on a hyperpolarized marker |
US9381257B2 (en) | 2012-07-13 | 2016-07-05 | Bracco Imaging S.P.A. | Triarylmethyl radicals |
CN102879754B (zh) * | 2012-09-19 | 2015-07-22 | 中国科学院电工研究所 | 一种用于质子电子双共振成像的磁场循环装置 |
US9874622B2 (en) | 2013-09-27 | 2018-01-23 | General Electric Company | Hyperpolarized media transport vessel |
US11498912B2 (en) | 2017-08-04 | 2022-11-15 | Ohio State Innovation Foundation | Radical compounds and methods of using thereof |
JP6789585B2 (ja) | 2017-08-23 | 2020-11-25 | 国立大学法人大阪大学 | 原子核スピンの高偏極化方法及び高偏極化装置 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8819754D0 (en) * | 1988-08-19 | 1988-09-21 | Nycomed As | Apparatus & method |
US5479925A (en) * | 1994-06-23 | 1996-01-02 | General Electric Company | Magnetic resonance (MR) angiography in a low-field imaging magnet |
GB9614139D0 (en) * | 1996-07-05 | 1996-09-04 | Nycomed Imaging As | Method |
-
1998
- 1998-06-19 EP EP98930914A patent/EP0990168A1/en not_active Ceased
- 1998-06-19 WO PCT/GB1998/001814 patent/WO1998058272A1/en not_active Application Discontinuation
- 1998-06-19 CN CN98806372.7A patent/CN1269015A/zh active Pending
- 1998-06-19 AU AU81192/98A patent/AU8119298A/en not_active Abandoned
- 1998-06-19 CA CA002290808A patent/CA2290808A1/en not_active Abandoned
- 1998-06-19 JP JP50400399A patent/JP2002508687A/ja active Pending
-
1999
- 1999-12-13 US US09/460,094 patent/US6311086B1/en not_active Expired - Lifetime
- 1999-12-14 NO NO996173A patent/NO996173L/no unknown
Also Published As
Publication number | Publication date |
---|---|
AU8119298A (en) | 1999-01-04 |
CA2290808A1 (en) | 1998-12-23 |
NO996173D0 (no) | 1999-12-14 |
US6311086B1 (en) | 2001-10-30 |
CN1269015A (zh) | 2000-10-04 |
WO1998058272A1 (en) | 1998-12-23 |
EP0990168A1 (en) | 2000-04-05 |
JP2002508687A (ja) | 2002-03-19 |
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