NO995858D0 - New class of cationic nucleic acid transfer agents - Google Patents

New class of cationic nucleic acid transfer agents

Info

Publication number
NO995858D0
NO995858D0 NO995858A NO995858A NO995858D0 NO 995858 D0 NO995858 D0 NO 995858D0 NO 995858 A NO995858 A NO 995858A NO 995858 A NO995858 A NO 995858A NO 995858 D0 NO995858 D0 NO 995858D0
Authority
NO
Norway
Prior art keywords
nucleic acid
transfer agents
new class
acid transfer
cationic
Prior art date
Application number
NO995858A
Other languages
Norwegian (no)
Other versions
NO314147B1 (en
NO995858L (en
Inventor
Michel Bessodes
Daniel Scherman
Jean Herscovici
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of NO995858D0 publication Critical patent/NO995858D0/en
Publication of NO995858L publication Critical patent/NO995858L/en
Publication of NO314147B1 publication Critical patent/NO314147B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18Acyclic radicals, substituted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids

Abstract

The invention concerns a novel class of nucleic acid cationic transfecting agents, characterised in that the transfecting agents comprise at least a lipophilic region associated with a cationic hydrophilic region, said cationic hydrophilic region consisting of a heterocycle with 5 or 6 atoms substituted by amino groups.
NO19995858A 1997-06-06 1999-11-30 Cationic Nucleic Acid Transfection Agents, Preparations Containing Their Use and Preparation NO314147B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9707014A FR2764304B1 (en) 1997-06-06 1997-06-06 NEW CLASS OF CATIONIC NUCLEIC ACID TRANSFECTANTS
PCT/FR1998/001112 WO1998055490A1 (en) 1997-06-06 1998-06-03 Novel class of nucleic acid cationic transfecting agents

Publications (3)

Publication Number Publication Date
NO995858D0 true NO995858D0 (en) 1999-11-30
NO995858L NO995858L (en) 1999-11-30
NO314147B1 NO314147B1 (en) 2003-02-03

Family

ID=9507684

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19995858A NO314147B1 (en) 1997-06-06 1999-11-30 Cationic Nucleic Acid Transfection Agents, Preparations Containing Their Use and Preparation

Country Status (18)

Country Link
EP (1) EP0986568B1 (en)
JP (1) JP2002504815A (en)
KR (1) KR20010013312A (en)
CN (1) CN1259134A (en)
AT (1) ATE214708T1 (en)
AU (1) AU737579B2 (en)
BR (1) BR9809953A (en)
CA (1) CA2292837A1 (en)
DE (1) DE69804302T2 (en)
DK (1) DK0986568T3 (en)
ES (1) ES2174445T3 (en)
FR (1) FR2764304B1 (en)
HU (1) HUP0004577A3 (en)
NO (1) NO314147B1 (en)
PL (1) PL337177A1 (en)
PT (1) PT986568E (en)
WO (1) WO1998055490A1 (en)
ZA (1) ZA984845B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999012945A2 (en) * 1997-09-08 1999-03-18 Valentis,Inc. Hydrophobic glycosylamine derivatives, compositions, and methods for use
DE19942864A1 (en) * 1999-09-08 2001-03-15 Knoell Hans Forschung Ev New O-aminoalkyl monosaccharide derivatives useful for control of bacterial, especially mycobacterial, and fungal infections
JP4629333B2 (en) * 2001-08-29 2011-02-09 アベンティス・ファーマ・ソシエテ・アノニム Lipid derivatives of aminoglycosides
FR2829136B1 (en) * 2001-08-29 2006-11-17 Aventis Pharma Sa LIPID DERIVATIVES OF AMINOGLYCOSIDES
WO2008045015A1 (en) 2005-06-08 2008-04-17 Amicus Therapeutics, Inc. Imino and amino sugar purification
JPWO2008081686A1 (en) * 2006-12-28 2010-04-30 コニカミノルタホールディングス株式会社 Cholesterol derivative, liposome, liposome formation method and X-ray contrast agent
EP3423438A4 (en) * 2016-03-01 2020-05-06 Molecular Transfer, Inc. Plant virus movement proteins and methods of using the same
SG11202101429YA (en) 2018-08-23 2021-03-30 Seagen Inc Anti-tigit antibodies

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2774417B2 (en) * 1991-08-07 1998-07-09 株式会社ディ・ディ・エス研究所 Branched-chain saccharide complex having peptide skeleton and fine particle carrier
DE4329093A1 (en) * 1993-08-30 1995-03-02 Bayer Ag Substituted aminoalkylglycosides
WO1996024334A1 (en) * 1995-02-10 1996-08-15 Nexstar Pharmaceuticals, Inc. Lipid constructs for cytoplasmic delivery of agents

Also Published As

Publication number Publication date
HUP0004577A1 (en) 2001-04-28
ZA984845B (en) 1998-12-29
FR2764304B1 (en) 1999-07-16
NO314147B1 (en) 2003-02-03
DE69804302D1 (en) 2002-04-25
DE69804302T2 (en) 2002-10-17
AU737579B2 (en) 2001-08-23
CA2292837A1 (en) 1998-12-10
HUP0004577A3 (en) 2003-03-28
CN1259134A (en) 2000-07-05
FR2764304A1 (en) 1998-12-11
BR9809953A (en) 2000-08-01
PT986568E (en) 2002-08-30
EP0986568A1 (en) 2000-03-22
KR20010013312A (en) 2001-02-26
JP2002504815A (en) 2002-02-12
PL337177A1 (en) 2000-08-14
ES2174445T3 (en) 2002-11-01
AU8025098A (en) 1998-12-21
NO995858L (en) 1999-11-30
ATE214708T1 (en) 2002-04-15
WO1998055490A1 (en) 1998-12-10
DK0986568T3 (en) 2002-06-10
EP0986568B1 (en) 2002-03-20

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