NO994821L - Method of inactivating pathogens, especially viruses, in a biological material - Google Patents

Method of inactivating pathogens, especially viruses, in a biological material

Info

Publication number
NO994821L
NO994821L NO994821A NO994821A NO994821L NO 994821 L NO994821 L NO 994821L NO 994821 A NO994821 A NO 994821A NO 994821 A NO994821 A NO 994821A NO 994821 L NO994821 L NO 994821L
Authority
NO
Norway
Prior art keywords
biological material
inactivating pathogens
especially viruses
mmol
incubation
Prior art date
Application number
NO994821A
Other languages
Norwegian (no)
Other versions
NO994821D0 (en
Inventor
Hans-Peter Schwarz
Gerold Zerlauth
Peter Turecek
Original Assignee
Baxter Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Ag filed Critical Baxter Ag
Publication of NO994821D0 publication Critical patent/NO994821D0/en
Publication of NO994821L publication Critical patent/NO994821L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0017—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Det er beskrevet en fremgangsmåte for inaktivering av patogener, spesielt virus, i et biologisk mate-riale ved inkubering med et kjemisk middel, som er kjennetegnet ved at inkuberingen foretas i nærvær av et eluotropt salt tilsvarende en NaCl-konsen-trasjon på minst 200 mmol/1, fortrinnsvis minst 3 00 mmol/1, samt et kromatografisk renset preparat som inneholder protrombinkompleks.A method is described for inactivating pathogens, especially viruses, in a biological material by incubation with a chemical agent, which is characterized by the fact that the incubation is carried out in the presence of an eluotropic salt corresponding to a NaCl concentration of at least 200 mmol /1, preferably at least 300 mmol/1, as well as a chromatographically purified preparation containing prothrombin complex.

NO994821A 1997-04-08 1999-10-04 Method of inactivating pathogens, especially viruses, in a biological material NO994821L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0059497A AT405608B (en) 1997-04-08 1997-04-08 METHOD FOR INACTIVATING PATHOGENS, ESPECIALLY VIRUSES, IN A BIOLOGICAL MATERIAL
PCT/AT1998/000090 WO1998044941A1 (en) 1997-04-08 1998-04-06 Method for inactivating pathogens, especially viruses, in a biological material

Publications (2)

Publication Number Publication Date
NO994821D0 NO994821D0 (en) 1999-10-04
NO994821L true NO994821L (en) 1999-12-02

Family

ID=3494721

Family Applications (1)

Application Number Title Priority Date Filing Date
NO994821A NO994821L (en) 1997-04-08 1999-10-04 Method of inactivating pathogens, especially viruses, in a biological material

Country Status (14)

Country Link
EP (1) EP0973543B1 (en)
JP (1) JP2001519790A (en)
AT (1) AT405608B (en)
AU (1) AU739845B2 (en)
BR (1) BR9807938A (en)
CA (1) CA2285976A1 (en)
DE (1) DE59810716D1 (en)
DK (1) DK0973543T3 (en)
ES (1) ES2214701T3 (en)
HU (1) HUP0000825A3 (en)
NO (1) NO994821L (en)
PT (1) PT973543E (en)
SK (1) SK138999A3 (en)
WO (1) WO1998044941A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10012732A1 (en) * 2000-03-18 2001-09-20 Aventis Behring Gmbh Thrombin composition, for use as hemostatic or as a component of fibrin glues, comprises non-covalently bonded inhibitor for stabilization
JP4855074B2 (en) * 2003-09-30 2012-01-18 一般財団法人化学及血清療法研究所 High-purity blood coagulation factor IX preparation and purification method thereof
PL1711513T3 (en) * 2003-12-01 2014-12-31 Novo Nordisk Healthcare Ag Nanofiltration of factor vii solutions to remove virus
US9493744B2 (en) 2012-06-20 2016-11-15 Genentech, Inc. Methods for viral inactivation and other adventitious agents

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT368883B (en) * 1980-07-22 1982-11-25 Immuno Ag METHOD FOR PRODUCING A NEW HUMAN PROTEIN-BASED PREPARATION PROCESSING BLOOD
ATE36457T1 (en) * 1983-05-02 1988-09-15 Immuno Ag METHOD OF INACTIVATING REPRODUCTIVE pathogens.
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
US4673733A (en) * 1985-04-11 1987-06-16 Sudhish Chandra Treatment of biological and pharmaceutical products adsorbed on a solid phase with virus and pyrogen inactivating agents
DE3730533A1 (en) * 1987-09-11 1989-03-30 Biotest Pharma Gmbh METHOD FOR STERILIZING PLASMA OR PLASMA FACTIONS
US5156973A (en) * 1988-11-23 1992-10-20 Edward Shanbrom Antiviral blood sampling process and apparatus
JP3145696B2 (en) * 1990-10-05 2001-03-12 日本ケミカルリサーチ株式会社 Method for producing secretory immunoglobulin A preparation
AT398079B (en) * 1991-11-04 1994-09-26 Immuno Ag PREPARATION WITH THROMBINE ACTIVITY AND METHOD FOR THEIR PRODUCTION
ZA93587B (en) * 1992-01-27 1994-07-07 Cryopharm Corp Method of freezing cells and cell like material
DE19506633A1 (en) * 1995-02-25 1996-08-29 Octapharma Ag Process for the preparation of factor IX from biological sources
FI952196A0 (en) * 1995-05-08 1995-05-08 Suomen Punainen Risti Veripalv Immunoglobulin production
DE19531637A1 (en) * 1995-08-28 1997-03-06 Immuno Ag Pharmaceutical composition for the treatment of blood coagulation disorders, method for the production thereof and their use
US6686191B1 (en) * 1995-09-22 2004-02-03 Bayer Healthcare Llc Preparation of virally inactivated intravenously injectable immune serum globulin

Also Published As

Publication number Publication date
AT405608B (en) 1999-10-25
HUP0000825A1 (en) 2000-07-28
NO994821D0 (en) 1999-10-04
EP0973543B1 (en) 2004-02-04
DK0973543T3 (en) 2004-05-24
ES2214701T3 (en) 2004-09-16
EP0973543A1 (en) 2000-01-26
AU6711898A (en) 1998-10-30
HUP0000825A3 (en) 2001-12-28
AU739845B2 (en) 2001-10-18
CA2285976A1 (en) 1998-10-15
ATA59497A (en) 1999-02-15
BR9807938A (en) 2000-02-22
DE59810716D1 (en) 2004-03-11
JP2001519790A (en) 2001-10-23
PT973543E (en) 2004-06-30
WO1998044941A1 (en) 1998-10-15
SK138999A3 (en) 2000-06-12

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application