NO994160L - Basic aluminum magnesium carbonate, process for its preparation and its use as a pharmaceutical preparation for the treatment of gastric acidity - Google Patents

Basic aluminum magnesium carbonate, process for its preparation and its use as a pharmaceutical preparation for the treatment of gastric acidity

Info

Publication number
NO994160L
NO994160L NO994160A NO994160A NO994160L NO 994160 L NO994160 L NO 994160L NO 994160 A NO994160 A NO 994160A NO 994160 A NO994160 A NO 994160A NO 994160 L NO994160 L NO 994160L
Authority
NO
Norway
Prior art keywords
preparation
magnesium carbonate
whose
aluminum magnesium
basic aluminum
Prior art date
Application number
NO994160A
Other languages
Norwegian (no)
Other versions
NO994160D0 (en
Inventor
Rafael Foguet
Santiago Gubert
Aurelio Sacristan
Josep M Castell
Jose A Ortiz
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of NO994160L publication Critical patent/NO994160L/en
Publication of NO994160D0 publication Critical patent/NO994160D0/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01FCOMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
    • C01F7/00Compounds of aluminium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10Carbonates; Bicarbonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01FCOMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
    • C01F7/00Compounds of aluminium
    • C01F7/78Compounds containing aluminium and two or more other elements, with the exception of oxygen and hydrogen
    • C01F7/784Layered double hydroxide, e.g. comprising nitrate, sulfate or carbonate ions as intercalating anions
    • C01F7/785Hydrotalcite
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01PINDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00Crystal-structural characteristics
    • C01P2002/70Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data
    • C01P2002/72Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data by d-values or two theta-values, e.g. as X-ray diagram
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01PINDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00Crystal-structural characteristics
    • C01P2002/70Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data
    • C01P2002/77Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data by unit-cell parameters, atom positions or structure diagrams
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01PINDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00Crystal-structural characteristics
    • C01P2002/80Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70
    • C01P2002/82Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70 by IR- or Raman-data
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01PINDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00Crystal-structural characteristics
    • C01P2002/80Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70
    • C01P2002/88Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70 by thermal analysis data, e.g. TGA, DTA, DSC
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01PINDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00Particle morphology
    • C01P2004/50Agglomerated particles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Geology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)

Abstract

Det er beskrevet et nytt basisk aluminium-magnesiumkarbonat av formelen (I) og med rhombohedrisk krystallisasjon, hvis nettparametre er a=b=3,046 Å, c-22,79 Å, a=B=90°; y=120° og cellevolum = 183 Å3, hvis røntgendiffraksjonsspektrum viser følgende d(Å) verdier: 7,597; 3,798; 2,6202; 2,5698; 2,5322; 2,2830, 1,93545, 1,72447; l 623930; 1,52289; 1,49318; 1,46002; 1,41351; 1,38528 og 1,31011; hvis infrarøde spektrum viser karakteristiske bånd ved 1361, 785 og 449 cm'1 (figur 1) og hvis differensielle sveipkalorimetri (DSC) er vist i figur 2. Denne forbindelsen anvendes som terapeutisk middel som et antacid og gastro- beskyttende middel.There is disclosed a new basic aluminum magnesium carbonate of formula (I) and with rhombohedric crystallization, whose mesh parameters are a = b = 3.046 Å, c-22.79 Å, a = B = 90 °; y = 120 ° and cell volume = 183 Å3, whose X-ray diffraction spectrum shows the following d (Å) values: 7.597; 3798; 2.6202; 2.5698; 2.5322; 2.2830, 1.93545, 1.72447; l 623930; 1.52289; 1.49318; 1.46002; 1.41351; 1.38528 and 1.31011; whose infrared spectrum shows characteristic bands at 1361, 785 and 449 cm -1 (Figure 1) and whose differential sweep calorimetry (DSC) is shown in Figure 2. This compound is used as a therapeutic agent as an antacid and gastroprotective agent.

NO994160A 1997-12-30 1999-08-27 Basic aluminum magnesium carbonate, process for its preparation and its use as a pharmaceutical preparation for the treatment of gastric acidity NO994160D0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009702717A ES2133136B1 (en) 1997-12-30 1997-12-30 NEW BASIC ALBUMINUM AND MAGNESIUM CARBONATE.
PCT/EP1998/008498 WO1999035088A1 (en) 1997-12-30 1998-12-29 Basic aluminum magnesium carbonate, method for the preparation thereof and its use as a pharmaceutical composition for treating stomach acidity

Publications (2)

Publication Number Publication Date
NO994160L true NO994160L (en) 1999-08-27
NO994160D0 NO994160D0 (en) 1999-08-27

Family

ID=8301660

Family Applications (1)

Application Number Title Priority Date Filing Date
NO994160A NO994160D0 (en) 1997-12-30 1999-08-27 Basic aluminum magnesium carbonate, process for its preparation and its use as a pharmaceutical preparation for the treatment of gastric acidity

Country Status (15)

Country Link
EP (1) EP0968133A1 (en)
JP (1) JP2001516328A (en)
KR (1) KR20000075839A (en)
AR (1) AR007232A1 (en)
AU (1) AU742544B2 (en)
BR (1) BR9807275A (en)
CA (1) CA2282361A1 (en)
ES (1) ES2133136B1 (en)
IL (1) IL131573A0 (en)
NO (1) NO994160D0 (en)
PA (1) PA8464401A1 (en)
PL (1) PL335464A1 (en)
RU (1) RU2168464C1 (en)
WO (1) WO1999035088A1 (en)
ZA (1) ZA9811216B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4338470B2 (en) * 2003-08-12 2009-10-07 日鉄鉱業株式会社 Hydrotalcite particles and method for producing the same
RU2540635C2 (en) * 2012-11-22 2015-02-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Национальный минерально-сырьевой университет "Горный" Production of alkaline metal hydrocarboaluminate from natural magnesium-bearing stock
CN108159072A (en) * 2017-12-04 2018-06-15 上海裕英生物医药科技有限公司 The preparation process of almagate
RU2678007C1 (en) * 2017-12-05 2019-01-22 Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр "Кольский научный центр Российской академии наук" (ФИЦ КНЦ РАН) Method of obtaining layered hydroxide of magnesium and aluminum

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3539306A (en) * 1966-07-25 1970-11-10 Kyowa Chem Ind Co Ltd Process for the preparation of hydrotalcite
US4904457A (en) * 1974-03-30 1990-02-27 Aluminum Company Of America Synthetic hydrotalcite
GB1598375A (en) * 1978-02-17 1981-09-16 Anphar Sa Aluminium magnesium carbonate
DE3306822C2 (en) * 1983-02-26 1985-01-03 Giulini Chemie Gmbh, 6700 Ludwigshafen Crystalline, basic aluminum-magnesium carbonate
WO1996005140A1 (en) * 1994-08-15 1996-02-22 Aluminum Company Of America Two powder synthesis of hydrotalcite and hydrotalcite-like compounds

Also Published As

Publication number Publication date
AU2276799A (en) 1999-07-26
IL131573A0 (en) 2001-01-28
AU742544B2 (en) 2002-01-03
AR007232A1 (en) 1999-10-27
ES2133136A1 (en) 1999-08-16
KR20000075839A (en) 2000-12-26
RU2168464C1 (en) 2001-06-10
JP2001516328A (en) 2001-09-25
ZA9811216B (en) 1999-07-14
ES2133136B1 (en) 2000-04-01
BR9807275A (en) 2000-05-02
NO994160D0 (en) 1999-08-27
WO1999035088A1 (en) 1999-07-15
PA8464401A1 (en) 2000-09-29
PL335464A1 (en) 2000-04-25
CA2282361A1 (en) 1999-07-15
EP0968133A1 (en) 2000-01-05

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