NO993438L - Ultrasound contrast agents - Google Patents
Ultrasound contrast agentsInfo
- Publication number
- NO993438L NO993438L NO993438A NO993438A NO993438L NO 993438 L NO993438 L NO 993438L NO 993438 A NO993438 A NO 993438A NO 993438 A NO993438 A NO 993438A NO 993438 L NO993438 L NO 993438L
- Authority
- NO
- Norway
- Prior art keywords
- sensitivity
- types
- contrast agents
- microparticle
- acoustic energy
- Prior art date
Links
- 239000002961 echo contrast media Substances 0.000 title 1
- 239000011859 microparticle Substances 0.000 abstract 5
- 230000035945 sensitivity Effects 0.000 abstract 5
- 238000002604 ultrasonography Methods 0.000 abstract 2
- 239000002872 contrast media Substances 0.000 abstract 1
- 238000012285 ultrasound imaging Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Acoustics & Sound (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Kontrastmidler til ultralydavbilding som inneholder to eller flere typer gassinneholdende mikropartikler som har forskjellig følsomhet overfor ultralydtrykk. Mikropartikkeltyper med' relativt lav følsomhet overfor ultralydtrykk gir en respons på høy akustisk energi i nærfeltet der mikropartikkeltyper med relativt høy følsomhet har lett for å bli ødelagt. Mikropartikkeltyper med høyere følsomhet er effektive i fjernfeltets miljø med lavere akustisk energi, der mikropartikkeltyper med lavere følsomhet ikke gir særlig respons.Ultrasound imaging contrast agents containing two or more types of gas-containing microparticles having different ultrasound pressure sensitivity. Microparticle types with 'relatively low sensitivity to ultrasound pressure provide a response to high acoustic energy in the near field where microparticle types with relatively high sensitivity are easily destroyed. Higher sensitivity microparticle types are effective in the far field environment with lower acoustic energy, where microparticle types with lower sensitivity give no particular response.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9701237.1A GB9701237D0 (en) | 1997-01-22 | 1997-01-22 | Improvements in or relating to contrast agents |
| PCT/GB1998/000189 WO1998032468A1 (en) | 1997-01-22 | 1998-01-22 | Contrast agents containing two types of gas filled microbubbles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO993438D0 NO993438D0 (en) | 1999-07-13 |
| NO993438L true NO993438L (en) | 1999-07-13 |
Family
ID=10806374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO993438A NO993438L (en) | 1997-01-22 | 1999-07-13 | Ultrasound contrast agents |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0966305A1 (en) |
| JP (1) | JP2001508454A (en) |
| CN (1) | CN1244131A (en) |
| AU (1) | AU5674098A (en) |
| CA (1) | CA2278750A1 (en) |
| GB (1) | GB9701237D0 (en) |
| NO (1) | NO993438L (en) |
| WO (1) | WO1998032468A1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999013916A2 (en) * | 1997-09-18 | 1999-03-25 | Nycomed Imaging As | Methods and compositions for medical imaging |
| DE602004029010D1 (en) | 2003-02-04 | 2010-10-21 | Bracco Suisse Sa | ULTRASONIC CONTRASTING AGENT AND METHOD OF CREATION |
| EP1701745B1 (en) | 2003-12-22 | 2014-12-10 | Bracco Suisse S.A. | Gas-filled microvesicle assembly for contrast imaging |
| US9248204B2 (en) | 2004-08-18 | 2016-02-02 | Bracco Suisse S.A. | Gas-filled microvesicles composition for contrast imaging |
| CN102112176B (en) * | 2008-07-23 | 2015-08-12 | 皇家飞利浦电子股份有限公司 | The drug delivery of ultrasonic mediation |
| KR101647164B1 (en) | 2008-09-26 | 2016-08-09 | 암브룩스, 인코포레이티드 | Modified animal erythropoietin polypeptides and their uses |
| CN109529033A (en) * | 2018-07-09 | 2019-03-29 | 彭盛 | A kind of stable oxygen carrier microvesicle and its preparation method and application |
| CN113521317B (en) * | 2021-07-01 | 2023-03-31 | 中国科学院深圳先进技术研究院 | Ultrasonic molecular composite imaging method for double-targeting tumor |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5585112A (en) * | 1989-12-22 | 1996-12-17 | Imarx Pharmaceutical Corp. | Method of preparing gas and gaseous precursor-filled microspheres |
| DE4100470A1 (en) * | 1991-01-09 | 1992-07-16 | Byk Gulden Lomberg Chem Fab | Echo contrast agent |
| PT711179E (en) * | 1993-07-30 | 2005-03-31 | Imcor Pharmaceutical Company | STABILIZED MICROBOLHES COMPOSITIONS FOR ULTRASOUND |
| GB9417941D0 (en) * | 1994-09-06 | 1994-10-26 | Nycomed Imaging As | Improvements in or relating to contrast agents |
-
1997
- 1997-01-22 GB GBGB9701237.1A patent/GB9701237D0/en active Pending
-
1998
- 1998-01-22 AU AU56740/98A patent/AU5674098A/en not_active Abandoned
- 1998-01-22 WO PCT/GB1998/000189 patent/WO1998032468A1/en active Application Filing
- 1998-01-22 CN CN 98801948 patent/CN1244131A/en active Pending
- 1998-01-22 EP EP98900940A patent/EP0966305A1/en not_active Ceased
- 1998-01-22 CA CA002278750A patent/CA2278750A1/en not_active Abandoned
- 1998-01-22 JP JP53172098A patent/JP2001508454A/en not_active Ceased
-
1999
- 1999-07-13 NO NO993438A patent/NO993438L/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2278750A1 (en) | 1998-07-30 |
| GB9701237D0 (en) | 1997-03-12 |
| EP0966305A1 (en) | 1999-12-29 |
| JP2001508454A (en) | 2001-06-26 |
| AU5674098A (en) | 1998-08-18 |
| NO993438D0 (en) | 1999-07-13 |
| CN1244131A (en) | 2000-02-09 |
| WO1998032468A1 (en) | 1998-07-30 |
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