NO991194L - Kontrollert-frigj°ring doseform av [R-(Z)-<alfa>-(metoksyimino)-<alfa>-(azabisyklo[2,2,2]okt-3-yl)acetonitril monohydroklorid - Google Patents

Kontrollert-frigj°ring doseform av [R-(Z)-<alfa>-(metoksyimino)-<alfa>-(azabisyklo[2,2,2]okt-3-yl)acetonitril monohydroklorid

Info

Publication number
NO991194L
NO991194L NO991194A NO991194A NO991194L NO 991194 L NO991194 L NO 991194L NO 991194 A NO991194 A NO 991194A NO 991194 A NO991194 A NO 991194A NO 991194 L NO991194 L NO 991194L
Authority
NO
Norway
Prior art keywords
alfa
methoxyimino
azabicyclo
oct
controlled
Prior art date
Application number
NO991194A
Other languages
English (en)
Norwegian (no)
Other versions
NO991194D0 (no
Inventor
Susan Marie Milosovich
William Muldoon
Joseph Sauer
James Albert Napper
Laurence Rousseau
Original Assignee
Smithkline Beecham Plc
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc, Smithkline Beecham Corp filed Critical Smithkline Beecham Plc
Publication of NO991194D0 publication Critical patent/NO991194D0/no
Publication of NO991194L publication Critical patent/NO991194L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
NO991194A 1996-09-12 1999-03-11 Kontrollert-frigj°ring doseform av [R-(Z)-<alfa>-(metoksyimino)-<alfa>-(azabisyklo[2,2,2]okt-3-yl)acetonitril monohydroklorid NO991194L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9619074.9A GB9619074D0 (en) 1996-09-12 1996-09-12 Composition
PCT/GB1997/002418 WO1998010762A2 (en) 1996-09-12 1997-09-08 Controlled release dosage form of r-(z)-alpha-methoxyimino-alpha-(1-azabicyclo2.2oct-c-yl)acetonitrile monohydrochloride

Publications (2)

Publication Number Publication Date
NO991194D0 NO991194D0 (no) 1999-03-11
NO991194L true NO991194L (no) 1999-03-11

Family

ID=10799833

Family Applications (1)

Application Number Title Priority Date Filing Date
NO991194A NO991194L (no) 1996-09-12 1999-03-11 Kontrollert-frigj°ring doseform av [R-(Z)-<alfa>-(metoksyimino)-<alfa>-(azabisyklo[2,2,2]okt-3-yl)acetonitril monohydroklorid

Country Status (22)

Country Link
EP (1) EP0929301A2 (de)
JP (1) JP2001500150A (de)
KR (1) KR20000036039A (de)
CN (2) CN1235544A (de)
AR (1) AR008176A1 (de)
AU (1) AU724086B2 (de)
BR (1) BR9711734A (de)
CA (1) CA2265661A1 (de)
CO (1) CO5031291A1 (de)
CZ (1) CZ83299A3 (de)
GB (1) GB9619074D0 (de)
HU (1) HUP9904401A3 (de)
ID (1) ID19589A (de)
IL (1) IL128781A0 (de)
MA (1) MA24359A1 (de)
NO (1) NO991194L (de)
NZ (1) NZ334268A (de)
PE (1) PE2499A1 (de)
PL (1) PL332074A1 (de)
TR (1) TR199900505T2 (de)
WO (1) WO1998010762A2 (de)
ZA (1) ZA978133B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2775597B1 (fr) * 1998-03-04 2001-04-20 Gattefosse Ets Sa Pellet administrable par voie orale apte a ameliorer la biodisponibilite de la substance active, procede de fabrication
PL342600A1 (en) 1998-03-11 2001-06-18 Smithkline Beecham Plc Composition
DE19918325A1 (de) * 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
FR2796840B1 (fr) * 1999-07-26 2003-06-20 Ethypharm Lab Prod Ethiques Comprimes faiblement doses et procede de preparation
US6733781B2 (en) * 2000-12-06 2004-05-11 Wyeth Fast dissolving tablet
PE20040134A1 (es) 2002-07-25 2004-03-06 Pharmacia Corp Forma de dosificacion de una vez al dia de pramipexol
US20060252820A1 (en) * 2003-04-25 2006-11-09 Tetsuya Suzuki Composition for oral administration containing alkylene dioxybenzene derivative
US20070009596A1 (en) * 2003-05-14 2007-01-11 Bruschi Stefano D L Controlled drug release composition resistant to in vivo mechanic stress
US20050142191A1 (en) * 2003-06-23 2005-06-30 Neurochem (International) Limited Pharmaceutical formulations of amyloid inhibiting compounds
JP2005272347A (ja) * 2004-03-24 2005-10-06 Ohara Yakuhin Kogyo Kk 固形製剤の製造方法
EP1778201B1 (de) * 2004-08-13 2014-07-16 Boehringer Ingelheim International GmbH Pramipexolhaltige pharmazeutische pelletzusammensetzungen mit verzögerter wirkstoffabgabe, deren herstellungsverfahren und anwendung
PL1789021T3 (pl) 2004-08-13 2012-04-30 Boehringer Ingelheim Int Preparat tabletkowy o przedłużonym uwalnianiu zawierający pramipeksol lub jego farmaceutycznie dopuszczalną sól
EP1970056A1 (de) * 2007-03-15 2008-09-17 Polichem S.A. Zeitspezifische Dosierformen mit verzögerter/pulsatiler Freisetzung
US9132096B1 (en) 2014-09-12 2015-09-15 Alkermes Pharma Ireland Limited Abuse resistant pharmaceutical compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2219636T3 (es) * 1989-04-13 2004-12-01 Beecham Group P.L.C. Nuevos compuestos.
GB9409718D0 (en) * 1994-05-14 1994-07-06 Smithkline Beecham Plc Novel compounds
GB9421472D0 (en) * 1994-10-25 1994-12-07 Smithkline Beecham Plc Novel methods
AR004178A1 (es) * 1995-07-29 1998-11-04 Smithkline Beecham Plc Procedimiento para la formulacion de un farmaco, una composicion farmaceutica obtenible mediante este procedimiento y el uso de la misma.

Also Published As

Publication number Publication date
WO1998010762A3 (en) 1998-06-04
NO991194D0 (no) 1999-03-11
CN1235544A (zh) 1999-11-17
CZ83299A3 (cs) 1999-08-11
CA2265661A1 (en) 1998-03-19
PL332074A1 (en) 1999-08-30
GB9619074D0 (en) 1996-10-23
BR9711734A (pt) 1999-08-24
KR20000036039A (ko) 2000-06-26
WO1998010762A2 (en) 1998-03-19
HUP9904401A2 (hu) 2000-06-28
IL128781A0 (en) 2000-01-31
CO5031291A1 (es) 2001-04-27
EP0929301A2 (de) 1999-07-21
AU4128897A (en) 1998-04-02
ID19589A (id) 1998-07-23
AU724086B2 (en) 2000-09-14
NZ334268A (en) 2000-10-27
AR008176A1 (es) 1999-12-09
PE2499A1 (es) 1999-03-24
HUP9904401A3 (en) 2001-03-28
TR199900505T2 (de) 1999-06-21
CN1446535A (zh) 2003-10-08
JP2001500150A (ja) 2001-01-09
MA24359A1 (fr) 1998-07-01
ZA978133B (en) 1999-04-12

Similar Documents

Publication Publication Date Title
NO991194L (no) Kontrollert-frigj°ring doseform av [R-(Z)-&lt;alfa&gt;-(metoksyimino)-&lt;alfa&gt;-(azabisyklo[2,2,2]okt-3-yl)acetonitril monohydroklorid
KR100246065B1 (en) Substituted 3-aminoquinuclidines
UA41355C2 (uk) Засіб для лікування нейро-сніду
NO995794L (no) Farmasoeytisk preparat inneholdende &#34;Lactobacillus casei rhamnosus&#34;
EE04854B1 (et) Oksabispidiinühendid, nende valmistamise meetod ning ravimvorm kasutamiseks südame arütmia raviks ja profülaktikaks
NO864336L (no) Fremgangsmaate for fremstilling av terapeutisk aktive n-substituerte-n-(3-(1,2,4-triazolo(4,3-6)pyridazin-6-yl)fenyl)alkanamider,-karbamater og -urinstoffer.
MX9200361A (es) Nuevo uso del antagonista de adenosina.
DE69713151D1 (de) Cyclosporinderivat, dessen herstellung und pharmazeutische zusammensetzung
BG103474A (en) Application of derivatives of 7-(2-oxa-5,8-diazobicyclo[4,3,0]non-8-8-yl)-quinoloncarboxylic acid and naphthyridoncarboxylic acid in the therapy of helicobacter pylor infections and the gastroduodenal diseases related to them
MY130208A (en) Quetiapine granules
NO922426L (no) Forbindelser med reninhemmende egenskaper, fremgangsmaate for fremstilling av disse og deres anvendelse
CA2123315A1 (en) Therapeutic agents which are antagonists or partial agonists of human interleukin 4
AU2002332488A8 (en) R-bambuterol, its preparation and therapeutic uses
NO983177L (no) Anvendelse av 1-enantiomeren av centkroman til fremstilling av et farmasaytisk preparat for behandling eller profylakse av brystkreft
MX9300927A (es) Compuestos terapeuticos de triazina y su empleo.
MXPA02006146A (es) Uso de metabolitos bioactivos de gepirona para el tratamiento de desordenes psicologicos.
TW349864B (en) Use of N-(pyridinyl)-1H-indol-a-amines for the preparation of a medicament for the treatment of obsessive-compulsive disorders
NO910372D0 (no) Fremgangsmaate for fremstilling av heksahydropyrrolo(2,3-b)indolkarbamater-, urea-, amider og beslektede forbindelser og deres anvendelse som medikamenter.
TR199900141T2 (xx) Bunama tedavisi ve/veya profilaksisi i�in form�lasyon.
ZA931099B (en) Heterocyclic compounds their use and preparation
NO943101L (no) 2,6-metano-2H-kinolizinderivat som 5-HT3-reseptorantagonist
WO1999015160A3 (en) Use of 6,7-substituted 2-aminotetralines suitable for preparing pharmaceutical composition for the therapeutic treatment of inflammatory and/or autoimmune pathologies
PE128999A1 (es) 1,2,4-triazolo[3,4-a]piridazina sustituida
NO914654L (no) Fremgangsmaate for fremstilling og anvendelse av beta-hydroksyetylaminer med 1,1-disubstituert cyklopropylrest
KR900007413A (ko) 에이즈 발병방지, 치료제 및 그 치료용 조성물